fumonisin b1 is a lipid of Sphingolipids (SP) class. Fumonisin b1 is associated with abnormalities such as Infection, Kidney Diseases, Liver diseases, DERMATITIS HERPETIFORMIS, FAMILIAL and Malnutrition. The involved functions are known as Gene Expression, Anabolism, Signal, Biosynthetic Pathways and Regulation. Fumonisin b1 often locates in Body tissue, Microsomes, microsomal membrane, Protoplasm and Mitochondria. The associated genes with fumonisin b1 are Genome, P4HTM gene, FATE1 gene, BCL2 gene and TMEM132D gene. The related lipids are dihydroceramide, ceramide 1-phosphate, Sphingolipids, Fatty Acids and Palmitates.
To understand associated biological information of fumonisin b1, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
fumonisin b1 is suspected in Infection, Kidney Diseases, Liver diseases, DERMATITIS HERPETIFORMIS, FAMILIAL, Malnutrition, Celiac Disease and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
---|
We collected disease MeSH terms mapped to the references associated with fumonisin b1
Lipid pathways are not clear in current pathway databases. We organized associated pathways with fumonisin b1 through full-text articles, including metabolic pathways or pathways of biological mechanisms.
Pathway name | Related literatures |
---|
Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
---|
Function | Cross reference | Weighted score | Related literatures |
---|
Lipid concept | Cross reference | Weighted score | Related literatures |
---|
Gene | Cross reference | Weighted score | Related literatures |
---|
There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
---|---|---|---|---|
Rentz SS et al. | Inhibition of sphingolipid biosynthesis decreases phosphorylated ERK2 in LLC-PK1 cells. | 2005 | Food Chem. Toxicol. | pmid:15582204 |
Liu C et al. | Occurrence of fumonisins B1 and B2 in asparagus from Shandong province, PR China. | 2005 | Food Addit Contam | pmid:16019842 |
Piva A et al. | Activated carbon does not prevent the toxicity of culture material containing fumonisin B1 when fed to weanling piglets. | 2005 | J. Anim. Sci. | pmid:16024715 |
Hwang D et al. | Effects of ceramide inhibition on experimental radiation-induced oral mucositis. | 2005 | Oral Surg Oral Med Oral Pathol Oral Radiol Endod | pmid:16122660 |
Deshmukh S et al. | Effects of Fusarium moniliforme culture material containing known levels of fumonisin B1 on progress of Salmonella Gallinarum infection in Japanese quail: clinical signs and hematologic studies. | 2005 | Avian Dis. | pmid:16094834 |
Kuroyanagi M et al. | Vacuolar processing enzyme is essential for mycotoxin-induced cell death in Arabidopsis thaliana. | 2005 | J. Biol. Chem. | pmid:16043487 |
Taranu I et al. | Mycotoxin fumonisin B1 alters the cytokine profile and decreases the vaccinal antibody titer in pigs. | 2005 | Toxicol. Sci. | pmid:15659571 |
Osuchowski MF et al. | Fumonisin B1-induced neurodegeneration in mice after intracerebroventricular infusion is concurrent with disruption of sphingolipid metabolism and activation of proinflammatory signaling. | 2005 | Neurotoxicology | pmid:15713342 |
Castoria R et al. | Occurrence of mycotoxin in Farro samples from southern Italy. | 2005 | J. Food Prot. | pmid:15726990 |
Paepens C et al. | Development of a liquid chromatography/tandem mass spectrometry method for the quantification of fumonisin B1, B2 and B3 in cornflakes. | 2005 | Rapid Commun. Mass Spectrom. | pmid:15973649 |
Halloy DJ et al. | Oral exposure to culture material extract containing fumonisins predisposes swine to the development of pneumonitis caused by Pasteurellamultocida. | 2005 | Toxicology | pmid:15979225 |
Osuchowski MF and Sharma RP | Fumonisin B1 induces necrotic cell death in BV-2 cells and murine cultured astrocytes and is antiproliferative in BV-2 cells while N2A cells and primary cortical neurons are resistant. | 2005 | Neurotoxicology | pmid:16005069 |
Javed T et al. | Comparative pathologic changes in broiler chicks on feed amended with Fusarium proliferatum culture material or purified fumonisin B1 and moniliformin. | 2005 | Mycopathologia | pmid:15983742 |
Rossi F et al. | Effect of Bt corn on broiler growth performance and fate of feed-derived DNA in the digestive tract. | 2005 | Poult. Sci. | pmid:16050119 |
Stone JM et al. | Arabidopsis AtSPL14, a plant-specific SBP-domain transcription factor, participates in plant development and sensitivity to fumonisin B1. | 2005 | Plant J. | pmid:15703061 |
Sakamoto H et al. | Host sphingolipid biosynthesis as a target for hepatitis C virus therapy. | 2005 | Nat. Chem. Biol. | pmid:16408072 |
Miazzo R et al. | Efficacy of sodium bentonite as a detoxifier of broiler feed contaminated with aflatoxin and fumonisin. | 2005 | Poult. Sci. | pmid:15685935 |
Bluhm BH and Woloshuk CP | Amylopectin induces fumonisin B1 production by Fusarium verticillioides during colonization of maize kernels. | 2005 | Mol. Plant Microbe Interact. | pmid:16478053 |
Del Bianchi M et al. | Effects of prolonged oral administration of aflatoxin B1 and fumonisin B1 in broiler chickens. | 2005 | Poult. Sci. | pmid:16479938 |
Cvetnić Z et al. | Toxigenic potential of Fusarium species isolated from non-harvested maize. | 2005 | Arh Hig Rada Toksikol | pmid:16180614 |
Chivasa S et al. | Extracellular ATP functions as an endogenous external metabolite regulating plant cell viability. | 2005 | Plant Cell | pmid:16199612 |
Cetin Y and Bullerman LB | Cytotoxicity of Fusarium mycotoxins to mammalian cell cultures as determined by the MTT bioassay. | 2005 | Food Chem. Toxicol. | pmid:15778016 |
Kouadio JH et al. | Comparative study of cytotoxicity and oxidative stress induced by deoxynivalenol, zearalenone or fumonisin B1 in human intestinal cell line Caco-2. | 2005 | Toxicology | pmid:16019124 |
He Q et al. | Myriocin prevents fumonisin B1-induced sphingoid base accumulation in mice liver without ameliorating hepatotoxicity. | 2005 | Food Chem. Toxicol. | pmid:15811577 |
Soriano JM et al. | Mechanism of action of sphingolipids and their metabolites in the toxicity of fumonisin B1. | 2005 | Prog. Lipid Res. | pmid:16266752 |
Tani M et al. | Mechanisms of sphingosine and sphingosine 1-phosphate generation in human platelets. | 2005 | J. Lipid Res. | pmid:16061940 |
He Q and Sharma RP | Inhibition of tumor necrosis factor alpha signaling by anti-tumor necrosis factor alpha antibodies and pentoxifylline is unable to prevent fumonisin hepatotoxicity in mice. | 2005 | Toxicon | pmid:16054185 |
Petrache I et al. | Ceramide upregulation causes pulmonary cell apoptosis and emphysema-like disease in mice. | 2005 | Nat. Med. | pmid:15852018 |
Tran ST et al. | Chronic effects of fumonisin B1 on ducks. | 2005 | Poult. Sci. | pmid:15685938 |
Gelineau-van Waes J et al. | Maternal fumonisin exposure and risk for neural tube defects: mechanisms in an in vivo mouse model. | 2005 | Birth Defects Res. Part A Clin. Mol. Teratol. | pmid:15959874 |
Sharma RP et al. | Lupus-prone NZBWF1/J mice, defective in cytokine signaling, are resistant to fumonisin hepatotoxicity despite accumulation of liver sphinganine. | 2005 | Toxicology | pmid:16159691 |
Cavaglieri LR et al. | Rhizobacteria and their potential to control Fusarium verticillioides: effect of maize bacterisation and inoculum density. | 2005 | Antonie Van Leeuwenhoek | pmid:15803383 |
Lerda D et al. | Fumonisins in foods from Cordoba (Argentina), presence and genotoxicity. | 2005 | Food Chem. Toxicol. | pmid:15778008 |
Shimamoto S et al. | Changes in ganglioside content affect the binding of Clostridium perfringens epsilon-toxin to detergent-resistant membranes of Madin-Darby canine kidney cells. | 2005 | Microbiol. Immunol. | pmid:15781998 |
Pagliuca G et al. | Simple method for the simultaneous isolation and determination of fumonisin B1 and its metabolite aminopentol-1 in swine liver by liquid chromatography--fluorescence detection. | 2005 | J. Chromatogr. B Analyt. Technol. Biomed. Life Sci. | pmid:15797527 |
Cortez-Rocha MO et al. | Occurrence of fumonisin B1 and hydrolyzed fumonisin B1 in Mexican nixtamalized cornmeal. | 2005 | Bull Environ Contam Toxicol | pmid:15768501 |
He Q et al. | Fumonisin B1 hepatotoxicity in mice is attenuated by depletion of Kupffer cells by gadolinium chloride. | 2005 | Toxicology | pmid:15590129 |
Becker KP et al. | Selective inhibition of juxtanuclear translocation of protein kinase C betaII by a negative feedback mechanism involving ceramide formed from the salvage pathway. | 2005 | J. Biol. Chem. | pmid:15546881 |
Pepeljnjak S et al. | Toxic effects of Ustilago maydis and fumonisin B1 in rats. | 2005 | Acta Pharm | pmid:16375823 |
Xia QZ et al. | [Spontaneous and induced programmed cell death in suspension cell cultures of cotton (Gossypium hirsutum L.)]. | 2005 | Shi Yan Sheng Wu Xue Bao | pmid:16231696 |
Cavaglieri L et al. | In vitro influence of bacterial mixtures on Fusarium verticillioides growth and fumonisin B1 production: effect of seeds treatment on maize root colonization. | 2005 | Lett. Appl. Microbiol. | pmid:16238641 |
Shephard GS et al. | Fumonisin mycotoxins in traditional Xhosa maize beer in South Africa. | 2005 | J. Agric. Food Chem. | pmid:16302789 |
Desjardins AE et al. | Identification and heritability of fumonisin insensitivity in Zea mays. | 2005 | Phytochemistry | pmid:16198380 |
Cavaglieri L et al. | Biocontrol of Bacillus subtilis against Fusarium verticillioides in vitro and at the maize root level. | 2005 Jun-Jul | Res. Microbiol. | pmid:15950130 |
Sjögren B et al. | Cholesterol depletion reduces serotonin binding and signaling via human 5-HT(7(a)) receptors. | 2006 | Eur. J. Pharmacol. | pmid:17064686 |
Giussani P et al. | Sphingosine-1-phosphate phosphohydrolase regulates endoplasmic reticulum-to-golgi trafficking of ceramide. | 2006 | Mol. Cell. Biol. | pmid:16782891 |
Luongo D et al. | Interactive effects of fumonisin B1 and alpha-zearalenol on proliferation and cytokine expression in Jurkat T cells. | 2006 | Toxicol In Vitro | pmid:16899350 |
Tessari EN et al. | Effects of aflatoxin B1 and fumonisin B1 on body weight, antibody titres and histology of broiler chicks. | 2006 | Br. Poult. Sci. | pmid:16787861 |
Voss KA et al. | The role of tumor necrosis factor alpha and the peroxisome proliferator-activated receptor alpha in modulating the effects of fumonisin in mouse liver. | 2006 | Toxicology | pmid:16574297 |
Itoh Y et al. | Involvement of de novo ceramide synthesis in radiocontrast-induced renal tubular cell injury. | 2006 | Kidney Int. | pmid:16408118 |