fumonisin b1 is a lipid of Sphingolipids (SP) class. Fumonisin b1 is associated with abnormalities such as Infection, Kidney Diseases, Liver diseases, DERMATITIS HERPETIFORMIS, FAMILIAL and Malnutrition. The involved functions are known as Gene Expression, Anabolism, Signal, Biosynthetic Pathways and Regulation. Fumonisin b1 often locates in Body tissue, Microsomes, microsomal membrane, Protoplasm and Mitochondria. The associated genes with fumonisin b1 are Genome, P4HTM gene, FATE1 gene, BCL2 gene and TMEM132D gene. The related lipids are dihydroceramide, ceramide 1-phosphate, Sphingolipids, Fatty Acids and Palmitates.
To understand associated biological information of fumonisin b1, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
fumonisin b1 is suspected in Infection, Kidney Diseases, Liver diseases, DERMATITIS HERPETIFORMIS, FAMILIAL, Malnutrition, Celiac Disease and other diseases in descending order of the highest number of associated sentences.
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We collected disease MeSH terms mapped to the references associated with fumonisin b1
Lipid pathways are not clear in current pathway databases. We organized associated pathways with fumonisin b1 through full-text articles, including metabolic pathways or pathways of biological mechanisms.
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Associated locations are in red color. Not associated locations are in black.
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Lipid concept | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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Dantzer WR et al. | Fumonisin B1 production by Fusarium proliferatum strain M5991 in a modified Myro liquid medium. | 1996 | Nat. Toxins | pmid:8887947 |
Rotter BA and Oh YN | Mycotoxin fumonisin B1 stimulates nitric oxide production in a murine macrophage cell line. | 1996 | Nat. Toxins | pmid:9029555 |
Li FQ et al. | Mycotoxins (trichothecenes, zearalenone and fumonisins) in cereals associated with human red-mold intoxications stored since 1989 and 1991 in China. | 1999 | Nat. Toxins | pmid:10647510 |
Wild CP et al. | Absence of a synergistic effect between fumonisin B1 and N-nitrosomethylbenzylamine in the induction of oesophageal papillomas in the rat. | 1997 | Nat. Toxins | pmid:9285918 |
Voss KA et al. | A preliminary investigation on renal and hepatic toxicity in rats fed purified fumonisin B1. | 1993 | Nat. Toxins | pmid:8167938 |
Norred WP et al. | Distribution and excretion of [14C]fumonisin B1 in male Sprague-Dawley rats. | 1993 | Nat. Toxins | pmid:8167955 |
Proctor RH et al. | Biosynthetic and genetic relationships of B-series fumonisins produced by Gibberella fujikuroi mating population A. | 1999 | Nat. Toxins | pmid:11122515 |
Picco M et al. | Aflatoxin B1 and fumosin B1 in mixed cultures of Aspergillus flavus and Fusarium proliferatum on maize. | 1999 | Nat. Toxins | pmid:11122525 |
Toxicology and carcinogenesis studies of fumonisin B1 (cas no. 116355-83-0) in F344/N rats and B6C3F1 mice (feed studies). | 2001 | Natl Toxicol Program Tech Rep Ser | pmid:11852482 | |
Galvano F et al. | DNA damage in astrocytes exposed to fumonisin B1. | 2002 | Neurochem. Res. | pmid:11958538 |
Callihan P et al. | Distinct generation, pharmacology, and distribution of sphingosine 1-phosphate and dihydrosphingosine 1-phosphate in human neural progenitor cells. | 2012 | Neuropharmacology | pmid:22016110 |
Plo I et al. | Involvement of de novo ceramide biosynthesis in lymphotoxin-induced oligodendrocyte death. | 1999 | Neuroreport | pmid:10439466 |
Yang MS et al. | Sphingomyelinase but not ceramide induces nitric oxide synthase expression in rat brain microglia. | 2001 | Neurosci. Lett. | pmid:11567796 |
Domijan AM et al. | Impact of fumonisin B1 on glutamate toxicity and low magnesium-induced seizure activity in neuronal primary culture. | 2012 | Neuroscience | pmid:22178271 |
Kwon OS et al. | Biochemical and morphological effects of fumonisin B(1) on primary cultures of rat cerebrum. | 2000 Jul-Aug | Neurotoxicol Teratol | pmid:10974595 |
Kwon OS et al. | Effects of fumonisin B1 treatment on blood-brain barrier transfer in developing rats. | 1997 Mar-Apr | Neurotoxicol Teratol | pmid:9136132 |
Poersch AB et al. | Fumonisin B1 facilitates seizures induced by pentylenetetrazol in mice. | Neurotoxicol Teratol | pmid:26342287 | |
Osuchowski MF et al. | Fumonisin B1-induced neurodegeneration in mice after intracerebroventricular infusion is concurrent with disruption of sphingolipid metabolism and activation of proinflammatory signaling. | 2005 | Neurotoxicology | pmid:15713342 |
Osuchowski MF and Sharma RP | Fumonisin B1 induces necrotic cell death in BV-2 cells and murine cultured astrocytes and is antiproliferative in BV-2 cells while N2A cells and primary cortical neurons are resistant. | 2005 | Neurotoxicology | pmid:16005069 |
Monnet-Tschudi F et al. | The naturally occurring food mycotoxin fumonisin B1 impairs myelin formation in aggregating brain cell culture. | 1999 | Neurotoxicology | pmid:10091857 |