fumonisin b1 is a lipid of Sphingolipids (SP) class. Fumonisin b1 is associated with abnormalities such as Infection, Kidney Diseases, Liver diseases, DERMATITIS HERPETIFORMIS, FAMILIAL and Malnutrition. The involved functions are known as Gene Expression, Anabolism, Signal, Biosynthetic Pathways and Regulation. Fumonisin b1 often locates in Body tissue, Microsomes, microsomal membrane, Protoplasm and Mitochondria. The associated genes with fumonisin b1 are Genome, P4HTM gene, FATE1 gene, BCL2 gene and TMEM132D gene. The related lipids are dihydroceramide, ceramide 1-phosphate, Sphingolipids, Fatty Acids and Palmitates.
To understand associated biological information of fumonisin b1, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
fumonisin b1 is suspected in Infection, Kidney Diseases, Liver diseases, DERMATITIS HERPETIFORMIS, FAMILIAL, Malnutrition, Celiac Disease and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
---|
We collected disease MeSH terms mapped to the references associated with fumonisin b1
Lipid pathways are not clear in current pathway databases. We organized associated pathways with fumonisin b1 through full-text articles, including metabolic pathways or pathways of biological mechanisms.
Pathway name | Related literatures |
---|
Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
---|
Function | Cross reference | Weighted score | Related literatures |
---|
Lipid concept | Cross reference | Weighted score | Related literatures |
---|
Gene | Cross reference | Weighted score | Related literatures |
---|
There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
---|---|---|---|---|
Voss KA et al. | An overview of rodent toxicities: liver and kidney effects of fumonisins and Fusarium moniliforme. | 2001 | Environ. Health Perspect. | pmid:11359694 |
Gelderblom WC et al. | Toxicity of culture material of Fusarium verticillioides strain MRC 826 to nonhuman primates. | 2001 | Environ. Health Perspect. | pmid:11359695 |
Howard PC et al. | Fumonisin b1 carcinogenicity in a two-year feeding study using F344 rats and B6C3F1 mice. | 2001 | Environ. Health Perspect. | pmid:11359696 |
Merrill AH et al. | Sphingolipid metabolism: roles in signal transduction and disruption by fumonisins. | 2001 | Environ. Health Perspect. | pmid:11359697 |
Gelderblom WC et al. | Fumonisin-induced hepatocarcinogenesis: mechanisms related to cancer initiation and promotion. | 2001 | Environ. Health Perspect. | pmid:11359698 |
Howard PC et al. | Compensatory regeneration as a mechanism for renal tubule carcinogenesis of fumonisin B1 in the F344/N/Nctr BR rat. | 2001 | Environ. Health Perspect. | pmid:11359700 |
Jones C et al. | Analysis of fumonisin B1-induced apoptosis. | 2001 | Environ. Health Perspect. | pmid:11359701 |
Miller JD | Factors that affect the occurrence of fumonisin. | 2001 | Environ. Health Perspect. | pmid:11359702 |
Bacon CW et al. | Biological control of Fusarium moniliforme in maize. | 2001 | Environ. Health Perspect. | pmid:11359703 |
Saunders DS et al. | Control of fumonisin: effects of processing. | 2001 | Environ. Health Perspect. | pmid:11359704 |
Duvick J | Prospects for reducing fumonisin contamination of maize through genetic modification. | 2001 | Environ. Health Perspect. | pmid:11359705 |
Shirima CP et al. | A prospective study of growth and biomarkers of exposure to aflatoxin and fumonisin during early childhood in Tanzania. | 2015 | Environ. Health Perspect. | pmid:25325363 |
Ridenour JB et al. | UBL1 of Fusarium verticillioides links the N-end rule pathway to extracellular sensing and plant pathogenesis. | 2014 | Environ. Microbiol. | pmid:24237664 |
Mary VS et al. | The aflatoxin B -fumonisin B toxicity in BRL-3A hepatocytes is associated to induction of cytochrome P450 activity and arachidonic acid metabolism. | 2017 | Environ. Toxicol. | pmid:28181396 |
Bezuidenhout CC et al. | Multiplex PCR-based detection of potential fumonisin-producing Fusarium in traditional African vegetables. | 2006 | Environ. Toxicol. | pmid:16841320 |
Goldfinger M et al. | Protein synthesis in plasma cells is regulated by crosstalk between endoplasmic reticulum stress and mTOR signaling. | 2011 | Eur. J. Immunol. | pmid:21268018 |
Sjögren B et al. | Cholesterol depletion reduces serotonin binding and signaling via human 5-HT(7(a)) receptors. | 2006 | Eur. J. Pharmacol. | pmid:17064686 |
Wispriyono B et al. | A role for the de novo sphingolipids in apoptosis of photosensitized cells. | 2002 | Exp. Cell Res. | pmid:12213223 |
Suzuki A et al. | Sequential operation of ceramide synthesis and ICE cascade in CPT-11-initiated apoptotic death signaling. | 1997 | Exp. Cell Res. | pmid:9184074 |
Isogai C et al. | Analysis of bax protein in sphingosine-induced apoptosis in the human leukemic cell line TF1 and its bcl-2 transfectants. | 1998 | Exp. Hematol. | pmid:9808050 |