fumonisin b1 is a lipid of Sphingolipids (SP) class. Fumonisin b1 is associated with abnormalities such as Infection, Kidney Diseases, Liver diseases, DERMATITIS HERPETIFORMIS, FAMILIAL and Malnutrition. The involved functions are known as Gene Expression, Anabolism, Signal, Biosynthetic Pathways and Regulation. Fumonisin b1 often locates in Body tissue, Microsomes, microsomal membrane, Protoplasm and Mitochondria. The associated genes with fumonisin b1 are Genome, P4HTM gene, FATE1 gene, BCL2 gene and TMEM132D gene. The related lipids are dihydroceramide, ceramide 1-phosphate, Sphingolipids, Fatty Acids and Palmitates.
To understand associated biological information of fumonisin b1, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
fumonisin b1 is suspected in Infection, Kidney Diseases, Liver diseases, DERMATITIS HERPETIFORMIS, FAMILIAL, Malnutrition, Celiac Disease and other diseases in descending order of the highest number of associated sentences.
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We collected disease MeSH terms mapped to the references associated with fumonisin b1
Lipid pathways are not clear in current pathway databases. We organized associated pathways with fumonisin b1 through full-text articles, including metabolic pathways or pathways of biological mechanisms.
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Associated locations are in red color. Not associated locations are in black.
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Gene | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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Bondy GS et al. | Toxicity of fumonisin B1 to B6C3F1 mice: a 14-day gavage study. | 1997 Oct-Nov | Food Chem. Toxicol. | pmid:9463532 |
Hlywka JJ et al. | The use of the chicken embryo screening test and brine shrimp (Artemia salina) bioassays to assess the toxicity of fumonisin B1 mycotoxin. | 1997 Oct-Nov | Food Chem. Toxicol. | pmid:9463533 |
Akiyama H et al. | Quantitation of fumonisins in corn by HPLC with o-phthalaldehyde postcolumn derivatization and their identification by LC/MS. | 1997-1998 | Mycopathologia | pmid:9735014 |
Bondy GS et al. | Gavage administration of the fungal toxin fumonisin B1 to female Sprague-Dawley rats. | 1998 | J. Toxicol. Environ. Health Part A | pmid:9444317 |
Sweeney MJ and Dobson AD | Mycotoxin production by Aspergillus, Fusarium and Penicillium species. | 1998 | Int. J. Food Microbiol. | pmid:9801191 |
Collins TF et al. | Effects of fumonisin B1 in pregnant rats. | 1998 | Food Chem. Toxicol. | pmid:9662415 |
Atroshi F et al. | Effects of tamoxifen, melatonin, coenzyme Q10, and L-carnitine supplementation on bacterial growth in the presence of mycotoxins. | 1998 | Pharmacol. Res. | pmid:9774492 |
Dugyala RR et al. | Tumor necrosis factor-alpha as a contributor in fumonisin B1 toxicity. | 1998 | J. Pharmacol. Exp. Ther. | pmid:9536027 |
Wieder T et al. | Induction of ceramide-mediated apoptosis by the anticancer phospholipid analog, hexadecylphosphocholine. | 1998 | J. Biol. Chem. | pmid:9556584 |
Abeywickrama K et al. | Effects of Fusarium moniliforme culture extracts and fumonisin B1 on DNA, RNA and protein synthesis by baby hamster kidney cells. | 1998 | Mycopathologia | pmid:10205886 |
Rösner H | Significance of gangliosides in neuronal differentiation of neuroblastoma cells and neurite growth in tissue culture. | 1998 | Ann. N. Y. Acad. Sci. | pmid:9668353 |
Hatch GM and McClarty G | Phospholipid composition of purified Chlamydia trachomatis mimics that of the eucaryotic host cell. | 1998 | Infect. Immun. | pmid:9673255 |
Schmelz EM et al. | Induction of apoptosis by fumonisin B1 in HT29 cells is mediated by the accumulation of endogenous free sphingoid bases. | 1998 | Toxicol. Appl. Pharmacol. | pmid:9473533 |
Voss KA et al. | In vivo effects of fumonisin B1-producing and fumonisin B1-nonproducing Fusarium moniliforme isolates are similar: fumonisins B2 and B3 cause hepato- and nephrotoxicity in rats. | 1998 | Mycopathologia | pmid:9725030 |
Auzenne E et al. | Cytotoxic effects of sphingolipids as single or multi-modality agents on human melanoma and soft tissue sarcoma in vitro. | 1998 | Melanoma Res. | pmid:9664144 |
Tsunoda M et al. | Early fumonisin B1 toxicity in relation to disrupted sphingolipid metabolism in male BALB/c mice. | 1998 | J. Biochem. Mol. Toxicol. | pmid:9664234 |
Humpf HU et al. | Acylation of naturally occurring and synthetic 1-deoxysphinganines by ceramide synthase. Formation of N-palmitoyl-aminopentol produces a toxic metabolite of hydrolyzed fumonisin, AP1, and a new category of ceramide synthase inhibitor. | 1998 | J. Biol. Chem. | pmid:9668088 |
Abel S and Gelderblom WC | Oxidative damage and fumonisin B1-induced toxicity in primary rat hepatocytes and rat liver in vivo. | 1998 | Toxicology | pmid:9928627 |
van der Westhuizen L et al. | Inhibition of sphingolipid biosynthesis in rat primary hepatocyte cultures by fumonisin B1 and other structurally related compounds. | 1998 | Food Chem. Toxicol. | pmid:9674957 |
Kutuzov MA et al. | Expression and characterization of PP7, a novel plant protein Ser/Thr phosphatase distantly related to RdgC/PPEF and PP5. | 1998 | FEBS Lett. | pmid:9862444 |