fumonisin b1
fumonisin b1 is a lipid of Sphingolipids (SP) class. Fumonisin b1 is associated with abnormalities such as Infection, Kidney Diseases, Liver diseases, DERMATITIS HERPETIFORMIS, FAMILIAL and Malnutrition. The involved functions are known as Gene Expression, Anabolism, Signal, Biosynthetic Pathways and Regulation. Fumonisin b1 often locates in Body tissue, Microsomes, microsomal membrane, Protoplasm and Mitochondria. The associated genes with fumonisin b1 are Genome, P4HTM gene, FATE1 gene, BCL2 gene and TMEM132D gene. The related lipids are dihydroceramide, ceramide 1-phosphate, Sphingolipids, Fatty Acids and Palmitates.
Cross Reference
Introduction
To understand associated biological information of fumonisin b1, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with fumonisin b1?
fumonisin b1 is suspected in Infection, Kidney Diseases, Liver diseases, DERMATITIS HERPETIFORMIS, FAMILIAL, Malnutrition, Celiac Disease and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with fumonisin b1
PubChem Associated disorders and diseases
What pathways are associated with fumonisin b1
Lipid pathways are not clear in current pathway databases. We organized associated pathways with fumonisin b1 through full-text articles, including metabolic pathways or pathways of biological mechanisms.
Related references are published most in these journals:
| Pathway name | Related literatures |
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PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with fumonisin b1?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
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What functions are associated with fumonisin b1?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
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What lipids are associated with fumonisin b1?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
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What genes are associated with fumonisin b1?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
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What common seen animal models are associated with fumonisin b1?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with fumonisin b1
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Osuchowski MF et al. | Fumonisin B1-induced neurodegeneration in mice after intracerebroventricular infusion is concurrent with disruption of sphingolipid metabolism and activation of proinflammatory signaling. | 2005 | Neurotoxicology | pmid:15713342 |
| Saucedo-GarcÃa M et al. | MPK6, sphinganine and the LCB2a gene from serine palmitoyltransferase are required in the signaling pathway that mediates cell death induced by long chain bases in Arabidopsis. | 2011 | New Phytol. | pmid:21534970 |
| Wolf G | Inhibition of cellular uptake of folate by blocking synthesis of the membrane folate receptor. | 1998 | Nutr. Rev. | pmid:9564182 |
| Wolf G | Mechanism of the mitogenic and carcinogenic action of fumonisin B1, a mycotoxin. | 1994 | Nutr. Rev. | pmid:8090377 |
| White-Gilbertson S et al. | Ceramide synthase 6 modulates TRAIL sensitivity and nuclear translocation of active caspase-3 in colon cancer cells. | 2009 | Oncogene | pmid:19137010 |
| Kellerman TS et al. | Leukoencephalomalacia in two horses induced by oral dosing of fumonisin B1. | 1990 | Onderstepoort J. Vet. Res. | pmid:2293136 |
| Marasas WF et al. | Leukoencephalomalacia in a horse induced by fumonisin B1 isolated from Fusarium moniliforme. | 1988 | Onderstepoort J. Vet. Res. | pmid:3217091 |
| Hwang D et al. | Effects of ceramide inhibition on experimental radiation-induced oral mucositis. | 2005 | Oral Surg Oral Med Oral Pathol Oral Radiol Endod | pmid:16122660 |
| Nogueira TC et al. | Involvement of phosphatidylinositol-3 kinase/AKT/PKCzeta/lambda pathway in the effect of palmitate on glucose-induced insulin secretion. | 2008 | Pancreas | pmid:18815554 |
| Mazzoni E et al. | Field control of Fusarium ear rot, Ostrinia nubilalis (Hübner), and fumonisins in maize kernels. | 2011 | Pest Manag. Sci. | pmid:21394878 |
| Demirel G et al. | Role of fumonisin B1 on DNA methylation changes in rat kidney and liver cells. | 2015 | Pharm Biol | pmid:25858139 |
| Eichele K et al. | R(+)-methanandamide-induced apoptosis of human cervical carcinoma cells involves a cyclooxygenase-2-dependent pathway. | 2009 | Pharm. Res. | pmid:19015962 |
| Atroshi F et al. | Fumonisin B1-induced DNA damage in rat liver and spleen: effects of pretreatment with coenzyme Q10, L-carnitine, alpha-tocopherol and selenium. | 1999 | Pharmacol. Res. | pmid:10660942 |
| Atroshi F et al. | Effects of tamoxifen, melatonin, coenzyme Q10, and L-carnitine supplementation on bacterial growth in the presence of mycotoxins. | 1998 | Pharmacol. Res. | pmid:9774492 |
| Dutton MF | Fumonisins, mycotoxins of increasing importance: their nature and their effects. | 1996 | Pharmacol. Ther. | pmid:8843466 |
| He Q et al. | Pharmacological antagonism of fumonisin B1 cytotoxicity in porcine renal epithelial cells (LLC-PK1): a model for reducing fumonisin-induced nephrotoxicity in vivo. | 2002 | Pharmacol. Toxicol. | pmid:12076308 |
| Boppana NB et al. | Ceramide synthase inhibitor fumonisin B1 inhibits apoptotic cell death in SCC17B human head and neck squamous carcinoma cells after Pc4 photosensitization. | 2014 | Photochem. Photobiol. Sci. | pmid:25266739 |
| Szabó A et al. | Oral administration of fumonisin B and T-2 individually and in combination affects hepatic total and mitochondrial membrane lipid profile of rabbits. | 2016 | Physiol Int | pmid:28229635 |
| Arias SL et al. | Toxin distribution and sphingoid base imbalances in Fusarium verticillioides-infected and fumonisin B1-watered maize seedlings. | 2016 | Phytochemistry | pmid:26903312 |
| Abbas HK et al. | Biological activities of synthetic analogues of Alternaria alternata toxin (AAL-toxin) and fumonisin in plant and mammalian cell cultures. | 1995 | Phytochemistry | pmid:8590636 |