fumonisin b1 is a lipid of Sphingolipids (SP) class. Fumonisin b1 is associated with abnormalities such as Infection, Kidney Diseases, Liver diseases, DERMATITIS HERPETIFORMIS, FAMILIAL and Malnutrition. The involved functions are known as Gene Expression, Anabolism, Signal, Biosynthetic Pathways and Regulation. Fumonisin b1 often locates in Body tissue, Microsomes, microsomal membrane, Protoplasm and Mitochondria. The associated genes with fumonisin b1 are Genome, P4HTM gene, FATE1 gene, BCL2 gene and TMEM132D gene. The related lipids are dihydroceramide, ceramide 1-phosphate, Sphingolipids, Fatty Acids and Palmitates.
To understand associated biological information of fumonisin b1, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
fumonisin b1 is suspected in Infection, Kidney Diseases, Liver diseases, DERMATITIS HERPETIFORMIS, FAMILIAL, Malnutrition, Celiac Disease and other diseases in descending order of the highest number of associated sentences.
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We collected disease MeSH terms mapped to the references associated with fumonisin b1
Lipid pathways are not clear in current pathway databases. We organized associated pathways with fumonisin b1 through full-text articles, including metabolic pathways or pathways of biological mechanisms.
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Associated locations are in red color. Not associated locations are in black.
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Gene | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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Schroeder JJ et al. | Disruption of sphingolipid metabolism and stimulation of DNA synthesis by fumonisin B1. A molecular mechanism for carcinogenesis associated with Fusarium moniliforme. | 1994 | J. Biol. Chem. | pmid:8106389 |
Shephard GS et al. | Determination of the mycotoxin fumonisin B1 and identification of its partially hydrolysed metabolites in the faeces of non-human primates. | 1994 | Food Chem. Toxicol. | pmid:8132161 |
Riley RT et al. | Dietary fumonisin B1 induces disruption of sphingolipid metabolism in Sprague-Dawley rats: a new mechanism of nephrotoxicity. | 1994 | J. Nutr. | pmid:8145083 |
Floss JL et al. | Developmental toxicity in hamsters of an aqueous extract of Fusarium moniliforme culture material containing known quantities of fumonisin B1. | 1994 | Vet Hum Toxicol | pmid:8154103 |
Dombrink-Kurtzman MA et al. | Lymphocyte cytotoxicity and erythrocytic abnormalities induced in broiler chicks by fumonisins B1 and B2 and moniliformin from Fusarium proliferatum. | 1993 | Mycopathologia | pmid:8159217 |
Chu FS and Li GY | Simultaneous occurrence of fumonisin B1 and other mycotoxins in moldy corn collected from the People's Republic of China in regions with high incidences of esophageal cancer. | 1994 | Appl. Environ. Microbiol. | pmid:8161178 |
Voss KA et al. | A preliminary investigation on renal and hepatic toxicity in rats fed purified fumonisin B1. | 1993 | Nat. Toxins | pmid:8167938 |
Norred WP et al. | Distribution and excretion of [14C]fumonisin B1 in male Sprague-Dawley rats. | 1993 | Nat. Toxins | pmid:8167955 |
Plumlee KH and Galey FD | Neurotoxic mycotoxins: a review of fungal toxins that cause neurological disease in large animals. | 1994 Jan-Feb | J. Vet. Intern. Med. | pmid:8176663 |
Dombrink-Kurtzman MA et al. | An optimized MTT bioassay for determination of cytotoxicity of fumonisins in turkey lymphocytes. | 1994 Mar-Apr | J AOAC Int | pmid:8199486 |
Scott PM and Lawrence GA | Stability and problems in recovery of fumonisins added to corn-based foods. | 1994 Mar-Apr | J AOAC Int | pmid:8199487 |
Visconti A and Doko MB | Survey of fumonisin production by Fusarium isolated from cereals in Europe. | 1994 Mar-Apr | J AOAC Int | pmid:8199488 |
Shephard GS et al. | Biliary excretion of the mycotoxin fumonisin B1 in rats. | 1994 | Food Chem. Toxicol. | pmid:8206448 |
Christley RM et al. | Leukoencephalomalacia in horses. | 1993 | Aust. Vet. J. | pmid:8216085 |
Merrill AH et al. | Fumonisin B1 inhibits sphingosine (sphinganine) N-acyltransferase and de novo sphingolipid biosynthesis in cultured neurons in situ. | 1993 | J. Biol. Chem. | pmid:8262970 |
Chamberlain WJ et al. | Levels of fumonisin B1 in corn naturally contaminated with aflatoxins. | 1993 | Food Chem. Toxicol. | pmid:8282284 |
Javed T et al. | Mortality in broiler chicks on feed amended with Fusarium proliferatum culture material or with purified fumonisin B1 and moniliformin. | 1993 | Mycopathologia | pmid:8302366 |
Javed T et al. | Embryopathic and embryocidal effects of purified fumonisin B1 or Fusarium proliferatum culture material extract on chicken embryos. | 1993 | Mycopathologia | pmid:8302367 |
Gelderblom WC et al. | Fumonisin B1 dosimetry in relation to cancer initiation in rat liver. | 1994 | Carcinogenesis | pmid:8313510 |
Harel R and Futerman AH | Inhibition of sphingolipid synthesis affects axonal outgrowth in cultured hippocampal neurons. | 1993 | J. Biol. Chem. | pmid:8314804 |