fumonisin b1
fumonisin b1 is a lipid of Sphingolipids (SP) class. Fumonisin b1 is associated with abnormalities such as Infection, Kidney Diseases, Liver diseases, DERMATITIS HERPETIFORMIS, FAMILIAL and Malnutrition. The involved functions are known as Gene Expression, Anabolism, Signal, Biosynthetic Pathways and Regulation. Fumonisin b1 often locates in Body tissue, Microsomes, microsomal membrane, Protoplasm and Mitochondria. The associated genes with fumonisin b1 are Genome, P4HTM gene, FATE1 gene, BCL2 gene and TMEM132D gene. The related lipids are dihydroceramide, ceramide 1-phosphate, Sphingolipids, Fatty Acids and Palmitates.
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Introduction
To understand associated biological information of fumonisin b1, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with fumonisin b1?
fumonisin b1 is suspected in Infection, Kidney Diseases, Liver diseases, DERMATITIS HERPETIFORMIS, FAMILIAL, Malnutrition, Celiac Disease and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with fumonisin b1
PubChem Associated disorders and diseases
What pathways are associated with fumonisin b1
Lipid pathways are not clear in current pathway databases. We organized associated pathways with fumonisin b1 through full-text articles, including metabolic pathways or pathways of biological mechanisms.
Related references are published most in these journals:
| Pathway name | Related literatures |
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PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with fumonisin b1?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
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What functions are associated with fumonisin b1?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
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What lipids are associated with fumonisin b1?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
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What genes are associated with fumonisin b1?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
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What common seen animal models are associated with fumonisin b1?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with fumonisin b1
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Véret J et al. | Ceramide synthase 4 and de novo production of ceramides with specific N-acyl chain lengths are involved in glucolipotoxicity-induced apoptosis of INS-1 β-cells. | 2011 | Biochem. J. | pmid:21592087 |
| Luttgeharm KD et al. | Substrate specificity, kinetic properties and inhibition by fumonisin B1 of ceramide synthase isoforms from Arabidopsis. | 2016 | Biochem. J. | pmid:26635357 |
| Gueguen G et al. | A lysophosphatidic acid analogue is revealed as a potent inhibitor of phosphatidylcholine synthesis, inducing apoptosis. | 2002 | Biochem. J. | pmid:12197836 |
| Lee JY et al. | Cell-cycle-dependent changes in ceramide levels preceding retinoblastoma protein dephosphorylation in G2/M. | 1998 | Biochem. J. | pmid:9716505 |
| Grenier B et al. | The low intestinal and hepatic toxicity of hydrolyzed fumonisin Bâ‚ correlates with its inability to alter the metabolism of sphingolipids. | 2012 | Biochem. Pharmacol. | pmid:22366513 |
| Loiseau N et al. | Fumonisin B1 exposure and its selective effect on porcine jejunal segment: sphingolipids, glycolipids and trans-epithelial passage disturbance. | 2007 | Biochem. Pharmacol. | pmid:17499218 |
| Paila YD et al. | Metabolic depletion of sphingolipids impairs ligand binding and signaling of human serotonin1A receptors. | 2010 | Biochemistry | pmid:20170167 |
| Babenko NA and Kharchenko VS | Effects of inhibitors of key enzymes of sphingolipid metabolism on insulin-induced glucose uptake and glycogen synthesis in liver cells of old rats. | 2015 | Biochemistry Mosc. | pmid:25754045 |
| Soeda S et al. | Daunorubicin attenuates tumor necrosis factor-alpha-induced biosynthesis of plasminogen activator inhibitor-1 in human umbilical vein endothelial cells. | 2001 | Biochim. Biophys. Acta | pmid:11336794 |
| Yin JJ et al. | Effects of fumonisin B1 on lipid peroxidation in membranes. | 1998 | Biochim. Biophys. Acta | pmid:9565668 |
| Patwardhan GA et al. | Ceramide modulates pre-mRNA splicing to restore the expression of wild-type tumor suppressor p53 in deletion-mutant cancer cells. | 2014 | Biochim. Biophys. Acta | pmid:25195822 |
| Badiani K et al. | Effect of fumonisin B1 on phosphatidylethanolamine biosynthesis in Chinese hamster ovary cells. | 1996 | Biochim. Biophys. Acta | pmid:8982265 |
| Pelagalli A et al. | The mycotoxin fumonisin B1 inhibits integrin-mediated cell-matrix adhesion. | 1999 | Biochimie | pmid:10575354 |
| Benedetti R et al. | Degradation of fumonisin B1 by a bacterial strain isolated from soil. | 2006 | Biodegradation | pmid:16453169 |
| Martynova EA et al. | [Modulation of the level of sphingomyelin cycle products and expression of the CD3 receptor in immunocompetent organs by fumonisin B1]. | 1995 | Biokhimiia | pmid:7779984 |
| Konoshima T et al. | Anti-tumor-promoting activity of majonoside-R2 from Vietnamese ginseng, Panax vietnamensis Ha et Grushv. (I). | 1998 | Biol. Pharm. Bull. | pmid:9743252 |
| Takasaki M et al. | Anti-carcinogenic activity of Taraxacum plant. I. | 1999 | Biol. Pharm. Bull. | pmid:10408234 |
| Martynova EA et al. | [TNF-induced apoptosis and necrosis in myeloleukemia cells HL-60 is regulated by reactive oxygen metabolites depending on a cell cycle phase]. | 2003 Jan-Feb | Biomed Khim | pmid:14569872 |
| Min WK et al. | Production and characterization of monoclonal antibody and its recombinant single chain variable fragment specific for a food-born mycotoxin, fumonisin B1. | 2010 | Bioprocess Biosyst Eng | pmid:19597742 |
| Fukuda S et al. | Preparation and characterization of anti-fumonisin monoclonal antibodies. | 1994 | Biosci. Biotechnol. Biochem. | pmid:7764867 |