fumonisin b1 is a lipid of Sphingolipids (SP) class. Fumonisin b1 is associated with abnormalities such as Infection, Kidney Diseases, Liver diseases, DERMATITIS HERPETIFORMIS, FAMILIAL and Malnutrition. The involved functions are known as Gene Expression, Anabolism, Signal, Biosynthetic Pathways and Regulation. Fumonisin b1 often locates in Body tissue, Microsomes, microsomal membrane, Protoplasm and Mitochondria. The associated genes with fumonisin b1 are Genome, P4HTM gene, FATE1 gene, BCL2 gene and TMEM132D gene. The related lipids are dihydroceramide, ceramide 1-phosphate, Sphingolipids, Fatty Acids and Palmitates.
To understand associated biological information of fumonisin b1, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
fumonisin b1 is suspected in Infection, Kidney Diseases, Liver diseases, DERMATITIS HERPETIFORMIS, FAMILIAL, Malnutrition, Celiac Disease and other diseases in descending order of the highest number of associated sentences.
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We collected disease MeSH terms mapped to the references associated with fumonisin b1
Lipid pathways are not clear in current pathway databases. We organized associated pathways with fumonisin b1 through full-text articles, including metabolic pathways or pathways of biological mechanisms.
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Associated locations are in red color. Not associated locations are in black.
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Lipid concept | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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El Bawab S et al. | Biochemical characterization of the reverse activity of rat brain ceramidase. A CoA-independent and fumonisin B1-insensitive ceramide synthase. | 2001 | J. Biol. Chem. | pmid:11278489 |
Chalfant CE et al. | FAS activation induces dephosphorylation of SR proteins; dependence on the de novo generation of ceramide and activation of protein phosphatase 1. | 2001 | J. Biol. Chem. | pmid:11502750 |
Riley RT et al. | Sphingolipid perturbations as mechanisms for fumonisin carcinogenesis. | 2001 | Environ. Health Perspect. | pmid:11359699 |
Lemke SL et al. | Deamination of fumonisin B(1) and biological assessment of reaction product toxicity. | 2001 | Chem. Res. Toxicol. | pmid:11170503 |
Toxicology and carcinogenesis studies of fumonisin B1 (cas no. 116355-83-0) in F344/N rats and B6C3F1 mice (feed studies). | 2001 | Natl Toxicol Program Tech Rep Ser | pmid:11852482 | |
Bailly JD et al. | Toxicity of Fusarium moniliforme culture material containing known levels of fumonisin B1 in ducks. | 2001 | Toxicology | pmid:11376861 |
Solfrizzo M et al. | Determination of fumonisins B1 and B2 in cornflakes by high performance liquid chromatography and immunoaffinity clean-up. | 2001 | Food Addit Contam | pmid:11304032 |
Casado JM et al. | Experimental subchronic mycotoxicoses in mice: individual and combined effects of dietary exposure to fumonisins and aflatoxin B1. | 2001 | Food Chem. Toxicol. | pmid:11346488 |
Soeda S et al. | Daunorubicin attenuates tumor necrosis factor-alpha-induced biosynthesis of plasminogen activator inhibitor-1 in human umbilical vein endothelial cells. | 2001 | Biochim. Biophys. Acta | pmid:11336794 |
Tseng TC and Liu CY | Occurrence of fumonisin B1 in maize imported into Taiwan. | 2001 | Int. J. Food Microbiol. | pmid:11322697 |
Kroesen BJ et al. | Induction of apoptosis through B-cell receptor cross-linking occurs via de novo generated C16-ceramide and involves mitochondria. | 2001 | J. Biol. Chem. | pmid:11278517 |
Shim WB and Woloshuk CP | Regulation of fumonisin B(1) biosynthesis and conidiation in Fusarium verticillioides by a cyclin-like (C-type) gene, FCC1. | 2001 | Appl. Environ. Microbiol. | pmid:11282612 |
Spotti M et al. | Fumonisin B1 carry-over into milk in the isolated perfused bovine udder. | 2001 | Vet Hum Toxicol | pmid:11308118 |
Miguet C et al. | Ceramide generation occurring during 7beta-hydroxycholesterol- and 7-ketocholesterol-induced apoptosis is caspase independent and is not required to trigger cell death. | 2001 | Cell Death Differ. | pmid:11313706 |
De Girolamo A et al. | Effect of processing on fumonisin concentration in corn flakes. | 2001 | J. Food Prot. | pmid:11348004 |
Chelule PK et al. | Exposure of rural and urban populations in KwaZulu Natal, South Africa, to fumonisin B(1) in maize. | 2001 | Environ. Health Perspect. | pmid:11333186 |
Proceedings of the International Conference on the Toxicology of Fumonisin. 28-30 June 1999, Arlington, Virginia. | 2001 | Environ. Health Perspect. | pmid:11359690 | |
Marasas WF | Discovery and occurrence of the fumonisins: a historical perspective. | 2001 | Environ. Health Perspect. | pmid:11359691 |
ApSimon JW | Structure, synthesis, and biosynthesis of fumonisin B1 and related compounds. | 2001 | Environ. Health Perspect. | pmid:11359692 |
Haschek WM et al. | Fumonisin toxicosis in swine: an overview of porcine pulmonary edema and current perspectives. | 2001 | Environ. Health Perspect. | pmid:11359693 |
Voss KA et al. | An overview of rodent toxicities: liver and kidney effects of fumonisins and Fusarium moniliforme. | 2001 | Environ. Health Perspect. | pmid:11359694 |
Gelderblom WC et al. | Toxicity of culture material of Fusarium verticillioides strain MRC 826 to nonhuman primates. | 2001 | Environ. Health Perspect. | pmid:11359695 |
Howard PC et al. | Fumonisin b1 carcinogenicity in a two-year feeding study using F344 rats and B6C3F1 mice. | 2001 | Environ. Health Perspect. | pmid:11359696 |
Merrill AH et al. | Sphingolipid metabolism: roles in signal transduction and disruption by fumonisins. | 2001 | Environ. Health Perspect. | pmid:11359697 |
Gelderblom WC et al. | Fumonisin-induced hepatocarcinogenesis: mechanisms related to cancer initiation and promotion. | 2001 | Environ. Health Perspect. | pmid:11359698 |
Howard PC et al. | Compensatory regeneration as a mechanism for renal tubule carcinogenesis of fumonisin B1 in the F344/N/Nctr BR rat. | 2001 | Environ. Health Perspect. | pmid:11359700 |
Jones C et al. | Analysis of fumonisin B1-induced apoptosis. | 2001 | Environ. Health Perspect. | pmid:11359701 |
Miller JD | Factors that affect the occurrence of fumonisin. | 2001 | Environ. Health Perspect. | pmid:11359702 |
Bacon CW et al. | Biological control of Fusarium moniliforme in maize. | 2001 | Environ. Health Perspect. | pmid:11359703 |
Hartl M and Humpf HU | Combined synthetic/CD strategy for the stereochemical assignment of the tricarballylic acid side chains of fumonisin B(1). | 2001 | J. Org. Chem. | pmid:11374984 |
Bezombes C et al. | Lysosomal sphingomyelinase is not solicited for apoptosis signaling. | 2001 | FASEB J. | pmid:11156942 |
Eppley RM | Preparatory isolation of mycotoxins from solid phase fungal cultures. | 2001 | Methods Mol. Biol. | pmid:11050990 |
Carlson DB et al. | Fumonisin B1 promotes aflatoxin B1 and N-methyl-N'-nitro-nitrosoguanidine-initiated liver tumors in rainbow trout. | 2001 | Toxicol. Appl. Pharmacol. | pmid:11264020 |
Zhang Y et al. | Identification of differentially expressed genes following treatment of monkey kidney cells with the mycotoxin fumonisin B(1). | 2001 | Food Chem. Toxicol. | pmid:11259850 |
Maragos CM et al. | Fluorescence polarization as a means for determination of fumonisins in maize. | 2001 | J. Agric. Food Chem. | pmid:11261998 |
Momany FA and Dombrink-Kurtzman MA | Molecular dynamics simulations on the mycotoxin fumonisin B1. | 2001 | J. Agric. Food Chem. | pmid:11262071 |
Schmidt K et al. | Regulated apical secretion of zymogens in rat pancreas. Involvement of the glycosylphosphatidylinositol-anchored glycoprotein GP-2, the lectin ZG16p, and cholesterol-glycosphingolipid-enriched microdomains. | 2001 | J. Biol. Chem. | pmid:11152672 |
Ziulkoski AL et al. | De novo synthesis and recycling pathways of sphingomyelin in rat Sertoli cells. | 2001 | Biochem. Biophys. Res. Commun. | pmid:11237757 |
Gumprecht LA et al. | Species and organ specificity of fumonisin-induced endothelial alterations: potential role in porcine pulmonary edema. | 2001 | Toxicology | pmid:11246126 |
van der Westhuizen L et al. | The effect of repeated gavage doses of fumonisin B1 on the sphinganine and sphingosine levels in vervet monkeys. | 2001 | Toxicon | pmid:11223085 |
Sharma RP et al. | Decreased fumonisin hepatotoxicity in mice with a targeted deletion of tumor necrosis factor receptor 1. | 2001 | Toxicology | pmid:11250056 |
Mathur S et al. | Fumonisin B(1) increases serum sphinganine concentration but does not alter serum sphingosine concentration or induce cardiovascular changes in milk-fed calves. | 2001 | Toxicol. Sci. | pmid:11248151 |
Mathur S et al. | Fumonisin B(1) is hepatotoxic and nephrotoxic in milk-fed calves. | 2001 | Toxicol. Sci. | pmid:11248152 |
Chourasia HK | Efficacy of ammonia in detoxification of fumonisin contaminated corn. | 2001 | Indian J. Exp. Biol. | pmid:11510139 |
Martins ML et al. | Fumonisins B1 and B2 in black tea and medicinal plants. | 2001 | J. Food Prot. | pmid:11510675 |
Ono EY et al. | Evaluation of fumonisin-aflatoxin co-occurrence in Brazilian corn hybrids by ELISA. | 2001 | Food Addit Contam | pmid:11469328 |
Omurtag GZ | Determination of fumonisin B1 and B2 in corn and corn-based products in Turkey by high-performance liquid chromatography. | 2001 | J. Food Prot. | pmid:11456195 |
Spotti M et al. | Fumonisin B1 metabolism by bovine liver microsomes. | 2001 | Vet. Res. Commun. | pmid:11519682 |
Yu CH et al. | Differential effects of fumonisin B1 on cell death in cultured cells: the significance of the elevated sphinganine. | 2001 | Arch. Pharm. Res. | pmid:11339633 |
Dilkin P et al. | Robotic automated clean-up for detection of fumonisins B1 and B2 in corn and corn-based feed by high-performance liquid chromatography. | 2001 | J Chromatogr A | pmid:11519801 |