fumonisin b1

fumonisin b1 is a lipid of Sphingolipids (SP) class. Fumonisin b1 is associated with abnormalities such as Infection, Kidney Diseases, Liver diseases, DERMATITIS HERPETIFORMIS, FAMILIAL and Malnutrition. The involved functions are known as Gene Expression, Anabolism, Signal, Biosynthetic Pathways and Regulation. Fumonisin b1 often locates in Body tissue, Microsomes, microsomal membrane, Protoplasm and Mitochondria. The associated genes with fumonisin b1 are Genome, P4HTM gene, FATE1 gene, BCL2 gene and TMEM132D gene. The related lipids are dihydroceramide, ceramide 1-phosphate, Sphingolipids, Fatty Acids and Palmitates.

Cross Reference

Introduction

To understand associated biological information of fumonisin b1, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with fumonisin b1?

fumonisin b1 is suspected in Infection, Kidney Diseases, Liver diseases, DERMATITIS HERPETIFORMIS, FAMILIAL, Malnutrition, Celiac Disease and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
Loading... please refresh the page if content is not showing up.

Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with fumonisin b1

MeSH term MeSH ID Detail
Chemical and Drug Induced Liver Injury D056486 39 associated lipids
Pneumonia, Bacterial D018410 16 associated lipids
Adenoma, Liver Cell D018248 2 associated lipids
Neuroectodermal Tumors, Primitive, Peripheral D018241 3 associated lipids
Weight Gain D015430 101 associated lipids
Testicular Diseases D013733 15 associated lipids
Swine Diseases D013553 16 associated lipids
Stomatitis D013280 14 associated lipids
Stomach Ulcer D013276 75 associated lipids
Spinal Cord Injuries D013119 34 associated lipids
Seizures D012640 87 associated lipids
Scrapie D012608 7 associated lipids
Salmonella Infections, Animal D012481 9 associated lipids
Pulmonary Edema D011654 23 associated lipids
Pseudorabies D011557 1 associated lipids
Prostatic Neoplasms D011471 126 associated lipids
Precancerous Conditions D011230 48 associated lipids
Poultry Diseases D011201 21 associated lipids
Pasteurella Infections D010326 8 associated lipids
Paralysis D010243 4 associated lipids
Neuronal Ceroid-Lipofuscinoses D009472 5 associated lipids
Neuroblastoma D009447 66 associated lipids
Neural Tube Defects D009436 5 associated lipids
Nervous System Diseases D009422 37 associated lipids
Mycoses D009181 18 associated lipids
Magnesium Deficiency D008275 9 associated lipids
Lung Neoplasms D008175 171 associated lipids
Lung Diseases D008171 37 associated lipids
Liver Neoplasms, Experimental D008114 46 associated lipids
Liver Cirrhosis, Experimental D008106 36 associated lipids
Leukemia, Myeloid D007951 52 associated lipids
Kidney Neoplasms D007680 29 associated lipids
Kidney Diseases D007674 29 associated lipids
Inflammation D007249 119 associated lipids
Hyperplasia D006965 34 associated lipids
Hydrocephalus D006849 6 associated lipids
Carcinoma, Hepatocellular D006528 140 associated lipids
Glioma D005910 112 associated lipids
Glioblastoma D005909 27 associated lipids
Gaucher Disease D005776 13 associated lipids
Fetal Resorption D005327 15 associated lipids
Fatty Liver D005234 48 associated lipids
Esophageal Neoplasms D004938 20 associated lipids
Death, Sudden D003645 12 associated lipids
Cleft Palate D002972 9 associated lipids
Choline Deficiency D002796 16 associated lipids
Cell Transformation, Neoplastic D002471 126 associated lipids
Cardiovascular Diseases D002318 24 associated lipids
Carcinoma D002277 18 associated lipids
Brain Diseases D001927 27 associated lipids
Per page 10 20 50 100 | Total 54

PubChem Associated disorders and diseases

What pathways are associated with fumonisin b1

Lipid pathways are not clear in current pathway databases. We organized associated pathways with fumonisin b1 through full-text articles, including metabolic pathways or pathways of biological mechanisms.

Related references are published most in these journals:

Pathway name Related literatures
Loading... please refresh the page if content is not showing up.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with fumonisin b1?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
Loading... please refresh the page if content is not showing up.

What functions are associated with fumonisin b1?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with fumonisin b1?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
Loading... please refresh the page if content is not showing up.

What genes are associated with fumonisin b1?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with fumonisin b1?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with fumonisin b1

Download all related citations
Per page 10 20 50 100 | Total 1278
Authors Title Published Journal PubMed Link
Jiménez M et al. Sugars and amino acids as factors affecting the synthesis of fumonisins in liquid cultures by isolates of the Gibberella fujikuroi complex. 2003 Int. J. Food Microbiol. pmid:14623384
Okino N et al. The reverse activity of human acid ceramidase. 2003 J. Biol. Chem. pmid:12764132
Blomqvist M et al. Selective lack of the C16:0 fatty acid isoform of sulfatide in pancreas of type II diabetic animal models. 2003 APMIS pmid:14510644
Avantaggiato G et al. Effects of muffin processing on fumonisins from 14C-labeled toxins produced in cultured corn kernels. 2003 J. Food Prot. pmid:14572226
Sharma RP et al. Increased expression of CD95-ligand and other apoptotic signaling factors by fumonisin B1, a hepatotoxic mycotoxin, in livers of mice lacking tumor necrosis factor alpha. 2003 Cytokine pmid:14596819
Gopee NV et al. Fumonisin B1-induced apoptosis is associated with delayed inhibition of protein kinase C, nuclear factor-kappaB and tumor necrosis factor alpha in LLC-PK1 cells. 2003 Chem. Biol. Interact. pmid:14597127
Cirillo T et al. Natural co-occurrence of deoxynivalenol and fumonisins B1 and B2 in Italian marketed foodstuffs. 2003 Food Addit Contam pmid:12881130
Oswald IP et al. Mycotoxin fumonisin B1 increases intestinal colonization by pathogenic Escherichia coli in pigs. 2003 Appl. Environ. Microbiol. pmid:14532038
Litvak DA et al. Modulators of ceramide metabolism sensitize colorectal cancer cells to chemotherapy: a novel treatment strategy. 2003 J. Gastrointest. Surg. pmid:12559195
Suomalainen L et al. Sphingosine-1-phosphate in inhibition of male germ cell apoptosis in the human testis. 2003 J. Clin. Endocrinol. Metab. pmid:14602806
Tran ST et al. Sphinganine to sphingosine ratio and predictive biochemical markers of fumonisin B1 exposure in ducks. 2003 Chem. Biol. Interact. pmid:12902153
Hinkovska-Galcheva V et al. Enhanced phagocytosis through inhibition of de novo ceramide synthesis. 2003 J. Biol. Chem. pmid:12424251
Cirillo T et al. Evaluation of conventional and organic italian foodstuffs for deoxynivalenol and fumonisins B(1) and B(2). 2003 J. Agric. Food Chem. pmid:14690407
Kim EK et al. Hidden fumonisin in corn flakes. 2003 Food Addit Contam pmid:12623665
Uchida Y et al. De novo ceramide synthesis participates in the ultraviolet B irradiation-induced apoptosis in undifferentiated cultured human keratinocytes. 2003 J. Invest. Dermatol. pmid:12648232
Beekrum S et al. Naturally occurring phenols: a detoxification strategy for fumonisin B1. 2003 Food Addit Contam pmid:12775468
El-Sayed AM et al. Occurrence of certain mycotoxins in corn and corn-based products and thermostability of fumonisin B1 during processing. 2003 Nahrung pmid:13678256
Gopee NV and Sharma RP Sphingoid bases and their phosphates: transient activation and delayed repression of protein kinase C isoforms and their possible involvement in fumonisin B1 cytotoxicity. 2003 Toxicology pmid:12699912
Kritzinger Q et al. Mycoflora and fumonisin mycotoxins associated with cowpea [Vigna unguiculata (L.) Walp] seeds. 2003 J. Agric. Food Chem. pmid:12670154
Koyanagi S et al. Elevation of de novo ceramide synthesis in tumor masses and the role of microsomal dihydroceramide synthase. 2003 Int. J. Cancer pmid:12672022
Hering H et al. Lipid rafts in the maintenance of synapses, dendritic spines, and surface AMPA receptor stability. 2003 J. Neurosci. pmid:12716933
Williams LD et al. Leaching and binding of fumonisins in soil microcosms. 2003 J. Agric. Food Chem. pmid:12537442
Zhao H et al. Anoxia and reoxygenation of human endothelial cells decrease ceramide glucosyltransferase expression and activates caspases. 2003 FASEB J. pmid:12586734
Leung LW et al. Inhibitors of glycosphingolipid biosynthesis reduce transepithelial electrical resistance in MDCK I and FRT cells. 2003 Am. J. Physiol., Cell Physiol. pmid:12490435
Ho JA and Durst RA Detection of fumonisin B1: comparison of flow-injection liposome immunoanalysis with high-performance liquid chromatography. 2003 Anal. Biochem. pmid:12479829
Mobio TA et al. Comparative study of the toxic effects of fumonisin B1 in rat C6 glioma cells and p53-null mouse embryo fibroblasts. 2003 Toxicology pmid:12504343
Seefelder W et al. Bound fumonisin B1: analysis of fumonisin-B1 glyco and amino acid conjugates by liquid chromatography-electrospray ionization-tandem mass spectrometry. 2003 J. Agric. Food Chem. pmid:12926916
van der Westhuizen L et al. Fumonisin contamination and fusarium incidence in corn from Santa Catarina, Brazil. 2003 J. Agric. Food Chem. pmid:12926917
Riebeling C et al. Two mammalian longevity assurance gene (LAG1) family members, trh1 and trh4, regulate dihydroceramide synthesis using different fatty acyl-CoA donors. 2003 J. Biol. Chem. pmid:12912983
Meyer K et al. Residue formation of fumonisin B1 in porcine tissues. 2003 Food Addit Contam pmid:12888389
Palencia E et al. Total fumonisins are reduced in tortillas using the traditional nixtamalization method of mayan communities. 2003 J. Nutr. pmid:14519811
Dilkin P et al. Toxicological effects of chronic low doses of aflatoxin B(1) and fumonisin B(1)-containing Fusarium moniliforme culture material in weaned piglets. 2003 Food Chem. Toxicol. pmid:12909268
Martynova EA et al. [TNF-induced apoptosis and necrosis in myeloleukemia cells HL-60 is regulated by reactive oxygen metabolites depending on a cell cycle phase]. 2003 Jan-Feb Biomed Khim pmid:14569872
Ledoux DR et al. Individual and combined effects of the Fusarium mycotoxins fumonisin B1 and moniliformin in broiler chicks. 2003 Oct-Dec Avian Dis. pmid:14708984
Cavaglieri L et al. Screening procedures for selecting rhizobacteria with biocontrol effects upon Fusarium verticillioides growth and fumonisin B1 production. 2004 Res. Microbiol. pmid:15501652
Petrinec Z et al. Fumonisin B1 causes multiple lesions in common carp (Cyprinus carpio). 2004 DTW. Dtsch. Tierarztl. Wochenschr. pmid:15503536
Yu MU et al. Altered de novo sphingolipid biosynthesis is involved in the serum deprivation-induced cell death in LLC-PK1 cells. 2004 J. Toxicol. Environ. Health Part A pmid:15513905
Yi F et al. Homocysteine activates NADH/NADPH oxidase through ceramide-stimulated Rac GTPase activity in rat mesangial cells. 2004 Kidney Int. pmid:15496169
Lang KS et al. Involvement of ceramide in hyperosmotic shock-induced death of erythrocytes. 2004 Cell Death Differ. pmid:14615798
Bouhet S et al. The mycotoxin fumonisin B1 alters the proliferation and the barrier function of porcine intestinal epithelial cells. 2004 Toxicol. Sci. pmid:14600282
Appierto V et al. Involvement of c-Fos in fenretinide-induced apoptosis in human ovarian carcinoma cells. 2004 Cell Death Differ. pmid:14647238
Sharma N et al. Augmented fumonisin B1 toxicity in co-cultures: evidence for crosstalk between macrophages and non-parenchymatous liver epithelial cells involving proinflammatory cytokines. 2004 Toxicology pmid:15363598
Gopee NV and Sharma RP Selective and transient activation of protein kinase C alpha by fumonisin B1, a ceramide synthase inhibitor mycotoxin, in cultured porcine renal cells. 2004 Life Sci. pmid:14729403
Kim EK et al. Liquid chromatographic determination of fumonisins B1, B2, and B3 in corn silage. 2004 J. Agric. Food Chem. pmid:14733494
Lu FG and Wong CS Radiation-induced apoptosis of oligodendrocytes and its association with increased ceramide and down-regulated protein kinase B/Akt activity. 2004 Int. J. Radiat. Biol. pmid:14761849
Sharma N et al. Sphingosine kinase activity confers resistance to apoptosis by fumonisin B1 in human embryonic kidney (HEK-293) cells. 2004 Chem. Biol. Interact. pmid:15607760
Park JW et al. Analysis of heat-processed corn foods for fumonisins and bound fumonisins. 2004 Food Addit Contam pmid:15799562
Naiker S and Odhav B Mycotic keratitis: profile of Fusarium species and their mycotoxins. 2004 Mycoses pmid:14998400
Vismer HF et al. Production of fumonisins by Fusarium verticillioides strains on solid and in a defined liquid medium--effects of L-methionine and inoculum. 2004 Mycopathologia pmid:15487327
Gopee NV and Sharma RP The mycotoxin fumonisin B1 transiently activates nuclear factor-kappaB, tumor necrosis factor alpha and caspase 3 via protein kinase Calpha-dependent pathway in porcine renal epithelial cells. 2004 Cell Biol. Toxicol. pmid:15499968