fumonisin b1 is a lipid of Sphingolipids (SP) class. Fumonisin b1 is associated with abnormalities such as Infection, Kidney Diseases, Liver diseases, DERMATITIS HERPETIFORMIS, FAMILIAL and Malnutrition. The involved functions are known as Gene Expression, Anabolism, Signal, Biosynthetic Pathways and Regulation. Fumonisin b1 often locates in Body tissue, Microsomes, microsomal membrane, Protoplasm and Mitochondria. The associated genes with fumonisin b1 are Genome, P4HTM gene, FATE1 gene, BCL2 gene and TMEM132D gene. The related lipids are dihydroceramide, ceramide 1-phosphate, Sphingolipids, Fatty Acids and Palmitates.
To understand associated biological information of fumonisin b1, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
fumonisin b1 is suspected in Infection, Kidney Diseases, Liver diseases, DERMATITIS HERPETIFORMIS, FAMILIAL, Malnutrition, Celiac Disease and other diseases in descending order of the highest number of associated sentences.
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We collected disease MeSH terms mapped to the references associated with fumonisin b1
Lipid pathways are not clear in current pathway databases. We organized associated pathways with fumonisin b1 through full-text articles, including metabolic pathways or pathways of biological mechanisms.
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Associated locations are in red color. Not associated locations are in black.
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Lipid concept | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
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Hard GC et al. | Rat kidney pathology induced by chronic exposure to fumonisin B1 includes rare variants of renal tubule tumor. | 2001 May-Jun | Toxicol Pathol | pmid:11442024 |
Gumprecht LA et al. | Development of fumonisin-induced hepatotoxicity and pulmonary edema in orally dosed swine: morphological and biochemical alterations. | 1998 Nov-Dec | Toxicol Pathol | pmid:9864095 |
Pósa R et al. | A comparative pathological finding in pigs exposed to fumonisin B1 and/or Mycoplasma hyopneumoniae. | 2016 | Toxicol Ind Health | pmid:25107460 |
Luongo D et al. | Interactive effects of fumonisin B1 and alpha-zearalenol on proliferation and cytokine expression in Jurkat T cells. | 2006 | Toxicol In Vitro | pmid:16899350 |
Minervini F et al. | Toxic effects induced by mycotoxin fumonisin B1 on equine spermatozoa: assessment of viability, sperm chromatin structure stability, ROS production and motility. | 2010 | Toxicol In Vitro | pmid:20541003 |
Bernabucci U et al. | Aflatoxin B1 and fumonisin B1 affect the oxidative status of bovine peripheral blood mononuclear cells. | 2011 | Toxicol In Vitro | pmid:21256206 |
Suzuki A and Tsutomi Y | Inductions of fibroblast-like morphology and high growth activity by low-dose CPT-11 in PC12 cells: role of tenascin. | 2000 | Toxicol In Vitro | pmid:10906440 |
Minervini F et al. | Toxicity and apoptosis induced by the mycotoxins nivalenol, deoxynivalenol and fumonisin B1 in a human erythroleukemia cell line. | 2004 | Toxicol In Vitro | pmid:14630058 |
Sancak D and Ozden S | Global histone modifications in Fumonisin B1 exposure in rat kidney epithelial cells. | 2015 | Toxicol In Vitro | pmid:26208285 |
Cortinovis C et al. | Effects of fumonisin B1 alone and combined with deoxynivalenol or zearalenone on porcine granulosa cell proliferation and steroid production. | 2014 | Theriogenology | pmid:24576714 |
Sadler TW et al. | Prevention of fumonisin B1-induced neural tube defects by folic acid. | 2002 | Teratology | pmid:12353213 |
Zomborszky-Kovács M et al. | Preliminary communication: examination of the harmful effect to fetuses of fumonisin B(1) in pregnant sows. | 2000 | Teratog., Carcinog. Mutagen. | pmid:10992276 |
Kozutsumi Y et al. | [Sphingolipid probe]. | 2002 | Tanpakushitsu Kakusan Koso | pmid:11915351 |
Shu M et al. | Anti-idiotypic nanobody: A strategy for development of sensitive and green immunoassay for Fumonisin Bâ‚. | 2015 | Talanta | pmid:26078175 |
Wu S et al. | Homogenous detection of fumonisin B(1) with a molecular beacon based on fluorescence resonance energy transfer between NaYF4: Yb, Ho upconversion nanoparticles and gold nanoparticles. | 2013 | Talanta | pmid:24148452 |
Di Nardo F et al. | A fluorescent immunochromatographic strip test using Quantum Dots for fumonisins detection. | 2016 | Talanta | pmid:26838431 |
Jiménez M et al. | Characterization of Gibberella fujikuroi complex isolates by fumonisin B1 and B2 analysis and by RAPD and restriction analysis of PCR-amplified internal transcribed spacers of ribosomal DNA. | 2000 | Syst. Appl. Microbiol. | pmid:11249025 |
Hinojo MJ et al. | Utility of the polymerase chain reaction-restriction fragment length polymorphisms of the intergenic spacer region of the rDNA for characterizing Gibberella fujikuroi isolates. | 2004 | Syst. Appl. Microbiol. | pmid:15612625 |
Suga K et al. | [Analysis of fumonisin B1 and B2 in beer and raw materials of beer by liquid chromatography/tandem mass spectrometry]. | 2004 | Shokuhin Eiseigaku Zasshi | pmid:15678940 |
Yoshinari T et al. | Inter-laboratory study of an LC-MS/MS method for simultaneous determination of fumonisin B1, B2 and B3 in corn. | 2013 | Shokuhin Eiseigaku Zasshi | pmid:24025204 |
Cuzzocrea S et al. | Inhibition of ceramide biosynthesis ameliorates pathological consequences of spinal cord injury. | 2009 | Shock | pmid:18838947 |
Cuzzocrea S et al. | Fumonisin b1 reduces the development of multiple organ failure induced by zymosan in mice. | 2009 | Shock | pmid:18650782 |
Xia QZ et al. | [Spontaneous and induced programmed cell death in suspension cell cultures of cotton (Gossypium hirsutum L.)]. | 2005 | Shi Yan Sheng Wu Xue Bao | pmid:16231696 |
Zhang X et al. | [Determination of fumonisins B1 and B2 in corn by high performance liquid chromatography with post-column derivatization method]. | 2012 | Se Pu | pmid:23256381 |
Baron CL and Malhotra V | Role of diacylglycerol in PKD recruitment to the TGN and protein transport to the plasma membrane. | 2002 | Science | pmid:11729268 |
Maekawa M et al. | Staurosporines decrease ORMDL proteins and enhance sphingomyelin synthesis resulting in depletion of plasmalemmal phosphatidylserine. | 2016 | Sci Rep | pmid:27805006 |
Xue KS et al. | Mitigation of Fumonisin Biomarkers by Green Tea Polyphenols in a High-Risk Population of Hepatocellular Carcinoma. | 2015 | Sci Rep | pmid:26626148 |
Czerwiecki L | [Determination of selected mycotoxins in food. II. Selection of optimal conditions for the determination of fumonisin B1 and B2 in corn products using high performance liquid chromatography]. | 1998 | Rocz Panstw Zakl Hig | pmid:9734229 |
Martins HM et al. | Occurrence of fumonisins in feed for swine and horses. | 2012 Jul-Sep | Rev Iberoam Micol | pmid:21907302 |
del RÃo GarcÃa JC et al. | [Evaluation of the cytotoxicity of aflatoxin and fumonisin in swine intestinal cells]. | 2007 | Rev Iberoam Micol | pmid:17604433 |
Kovács M et al. | Feed exposure to FB1 can aggravate pneumonic damages in pigs provoked by P. multocida. | 2016 | Res. Vet. Sci. | pmid:27663368 |
Cavaglieri L et al. | Screening procedures for selecting rhizobacteria with biocontrol effects upon Fusarium verticillioides growth and fumonisin B1 production. | 2004 | Res. Microbiol. | pmid:15501652 |
Cavaglieri L et al. | Biocontrol of Bacillus subtilis against Fusarium verticillioides in vitro and at the maize root level. | 2005 Jun-Jul | Res. Microbiol. | pmid:15950130 |
Ewuola EO and Egbunike GN | Effects of dietary fumonisin B1 on the onset of puberty, semen quality, fertility rates and testicular morphology in male rabbits. | 2010 | Reproduction | pmid:19917669 |
Kalo D and Roth Z | Involvement of the sphingolipid ceramide in heat-shock-induced apoptosis of bovine oocytes. | 2011 | Reprod. Fertil. Dev. | pmid:21871207 |
Hines HB et al. | Fumonisin B1 analysis with capillary electrophoresis-electrospray ionization mass spectrometry. | 1995 | Rapid Commun. Mass Spectrom. | pmid:7606046 |
Paepens C et al. | Development of a liquid chromatography/tandem mass spectrometry method for the quantification of fumonisin B1, B2 and B3 in cornflakes. | 2005 | Rapid Commun. Mass Spectrom. | pmid:15973649 |
Korfmacher WA et al. | Characterization of the mycotoxin fumonisin B1: comparison of thermospray, fast-atom bombardment and electrospray mass spectrometry. | 1991 | Rapid Commun. Mass Spectrom. | pmid:1841646 |
Bartók T et al. | Detection and characterization of twenty-eight isomers of fumonisin B1 (FB1) mycotoxin in a solid rice culture infected with Fusarium verticillioides by reversed-phase high-performance liquid chromatography/electrospray ionization time-of-flight and ion trap mass spectrometry. | 2010 | Rapid Commun. Mass Spectrom. | pmid:19960490 |
Josephs JL | Detection and characterization of fumonisin mycotoxins by liquid chromatography/electrospray ionization using ion trap and triple quadrupole mass spectrometry. | 1996 | Rapid Commun. Mass Spectrom. | pmid:8805843 |
Gelderblom WC et al. | Regulation of fatty acid biosynthesis as a possible mechanism for the mitoinhibitory effect of fumonisin B1 in primary rat hepatocytes. | 1999 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:10574646 |
Seegers JC et al. | Fumonisin B1 influenced the effects of arachidonic acid, prostaglandins E2 and A2 on cell cycle progression, apoptosis induction, tyrosine- and CDC2-kinase activity in oesophageal cancer cells. | 2000 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:10780872 |
Soriano JM et al. | Mechanism of action of sphingolipids and their metabolites in the toxicity of fumonisin B1. | 2005 | Prog. Lipid Res. | pmid:16266752 |
Porter JK et al. | Effects of Fusarium moniliforme and corn associated with equine leukoencephalomalacia on rat neurotransmitters and metabolites. | 1990 | Proc. Soc. Exp. Biol. Med. | pmid:1972578 |
Porter JK et al. | Neurotransmitters in rats fed fumonisin B1. | 1993 | Proc. Soc. Exp. Biol. Med. | pmid:7679795 |
Brandwagt BF et al. | A longevity assurance gene homolog of tomato mediates resistance to Alternaria alternata f. sp. lycopersici toxins and fumonisin B1. | 2000 | Proc. Natl. Acad. Sci. U.S.A. | pmid:10781105 |
Wang W et al. | Fumonisins and Alternaria alternata lycopersici toxins: sphinganine analog mycotoxins induce apoptosis in monkey kidney cells. | 1996 | Proc. Natl. Acad. Sci. U.S.A. | pmid:8622958 |
De Nadai C et al. | Nitric oxide inhibits tumor necrosis factor-alpha-induced apoptosis by reducing the generation of ceramide. | 2000 | Proc. Natl. Acad. Sci. U.S.A. | pmid:10792026 |
Kononenko GP et al. | [Application of competitive immunoenzyme assay for analysis of group B fumonisins]. | 1999 Mar-Apr | Prikl. Biokhim. Mikrobiol. | pmid:10368851 |
Khalil AA et al. | Protective role of probiotic lactic acid bacteria against dietary fumonisin B1-induced toxicity and DNA-fragmentation in sprague-dawley rats. | 2015 | Prep. Biochem. Biotechnol. | pmid:25036875 |