fumonisin b1 is a lipid of Sphingolipids (SP) class. Fumonisin b1 is associated with abnormalities such as Infection, Kidney Diseases, Liver diseases, DERMATITIS HERPETIFORMIS, FAMILIAL and Malnutrition. The involved functions are known as Gene Expression, Anabolism, Signal, Biosynthetic Pathways and Regulation. Fumonisin b1 often locates in Body tissue, Microsomes, microsomal membrane, Protoplasm and Mitochondria. The associated genes with fumonisin b1 are Genome, P4HTM gene, FATE1 gene, BCL2 gene and TMEM132D gene. The related lipids are dihydroceramide, ceramide 1-phosphate, Sphingolipids, Fatty Acids and Palmitates.
To understand associated biological information of fumonisin b1, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
fumonisin b1 is suspected in Infection, Kidney Diseases, Liver diseases, DERMATITIS HERPETIFORMIS, FAMILIAL, Malnutrition, Celiac Disease and other diseases in descending order of the highest number of associated sentences.
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We collected disease MeSH terms mapped to the references associated with fumonisin b1
Lipid pathways are not clear in current pathway databases. We organized associated pathways with fumonisin b1 through full-text articles, including metabolic pathways or pathways of biological mechanisms.
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Associated locations are in red color. Not associated locations are in black.
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Function | Cross reference | Weighted score | Related literatures |
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Gene | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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Bacon CW et al. | Biological control of Fusarium moniliforme in maize. | 2001 | Environ. Health Perspect. | pmid:11359703 |
Miller JD | Factors that affect the occurrence of fumonisin. | 2001 | Environ. Health Perspect. | pmid:11359702 |
Jones C et al. | Analysis of fumonisin B1-induced apoptosis. | 2001 | Environ. Health Perspect. | pmid:11359701 |
Howard PC et al. | Compensatory regeneration as a mechanism for renal tubule carcinogenesis of fumonisin B1 in the F344/N/Nctr BR rat. | 2001 | Environ. Health Perspect. | pmid:11359700 |
Riley RT et al. | Sphingolipid perturbations as mechanisms for fumonisin carcinogenesis. | 2001 | Environ. Health Perspect. | pmid:11359699 |
Gelderblom WC et al. | Fumonisin-induced hepatocarcinogenesis: mechanisms related to cancer initiation and promotion. | 2001 | Environ. Health Perspect. | pmid:11359698 |
Merrill AH et al. | Sphingolipid metabolism: roles in signal transduction and disruption by fumonisins. | 2001 | Environ. Health Perspect. | pmid:11359697 |
Howard PC et al. | Fumonisin b1 carcinogenicity in a two-year feeding study using F344 rats and B6C3F1 mice. | 2001 | Environ. Health Perspect. | pmid:11359696 |
Gelderblom WC et al. | Toxicity of culture material of Fusarium verticillioides strain MRC 826 to nonhuman primates. | 2001 | Environ. Health Perspect. | pmid:11359695 |
Voss KA et al. | An overview of rodent toxicities: liver and kidney effects of fumonisins and Fusarium moniliforme. | 2001 | Environ. Health Perspect. | pmid:11359694 |
Haschek WM et al. | Fumonisin toxicosis in swine: an overview of porcine pulmonary edema and current perspectives. | 2001 | Environ. Health Perspect. | pmid:11359693 |
ApSimon JW | Structure, synthesis, and biosynthesis of fumonisin B1 and related compounds. | 2001 | Environ. Health Perspect. | pmid:11359692 |
Marasas WF | Discovery and occurrence of the fumonisins: a historical perspective. | 2001 | Environ. Health Perspect. | pmid:11359691 |
Proceedings of the International Conference on the Toxicology of Fumonisin. 28-30 June 1999, Arlington, Virginia. | 2001 | Environ. Health Perspect. | pmid:11359690 | |
De Girolamo A et al. | Effect of processing on fumonisin concentration in corn flakes. | 2001 | J. Food Prot. | pmid:11348004 |
Casado JM et al. | Experimental subchronic mycotoxicoses in mice: individual and combined effects of dietary exposure to fumonisins and aflatoxin B1. | 2001 | Food Chem. Toxicol. | pmid:11346488 |
Yu CH et al. | Differential effects of fumonisin B1 on cell death in cultured cells: the significance of the elevated sphinganine. | 2001 | Arch. Pharm. Res. | pmid:11339633 |
Soeda S et al. | Daunorubicin attenuates tumor necrosis factor-alpha-induced biosynthesis of plasminogen activator inhibitor-1 in human umbilical vein endothelial cells. | 2001 | Biochim. Biophys. Acta | pmid:11336794 |
Chelule PK et al. | Exposure of rural and urban populations in KwaZulu Natal, South Africa, to fumonisin B(1) in maize. | 2001 | Environ. Health Perspect. | pmid:11333186 |
Tseng TC and Liu CY | Occurrence of fumonisin B1 in maize imported into Taiwan. | 2001 | Int. J. Food Microbiol. | pmid:11322697 |
Miguet C et al. | Ceramide generation occurring during 7beta-hydroxycholesterol- and 7-ketocholesterol-induced apoptosis is caspase independent and is not required to trigger cell death. | 2001 | Cell Death Differ. | pmid:11313706 |
Spotti M et al. | Fumonisin B1 carry-over into milk in the isolated perfused bovine udder. | 2001 | Vet Hum Toxicol | pmid:11308118 |
Solfrizzo M et al. | Determination of fumonisins B1 and B2 in cornflakes by high performance liquid chromatography and immunoaffinity clean-up. | 2001 | Food Addit Contam | pmid:11304032 |
Petersen A and Thorup I | Preliminary evaluation of fumonisins by the Nordic countries and occurrence of fumonisins (FB1 and FB2) in corn-based foods on the Danish market. | 2001 | Food Addit Contam | pmid:11304031 |
Humphreys SH et al. | A quantitative risk assessment for fumonisins B1 and B2 in US corn. | 2001 | Food Addit Contam | pmid:11304030 |
Henry MH and Wyatt RD | The toxicity of fumonisin B1, B2, and B3, individually and in combination, in chicken embryos. | 2001 | Poult. Sci. | pmid:11297276 |
Gelderblom WC et al. | Toxicological effects in rats chronically fed low dietary levels of fumonisin B(1). | 2001 | Toxicology | pmid:11295254 |
Dragan YP et al. | Implications of apoptosis for toxicity, carcinogenicity, and risk assessment: fumonisin B(1) as an example. | 2001 | Toxicol. Sci. | pmid:11294969 |
Shim WB and Woloshuk CP | Regulation of fumonisin B(1) biosynthesis and conidiation in Fusarium verticillioides by a cyclin-like (C-type) gene, FCC1. | 2001 | Appl. Environ. Microbiol. | pmid:11282612 |
Kroesen BJ et al. | Induction of apoptosis through B-cell receptor cross-linking occurs via de novo generated C16-ceramide and involves mitochondria. | 2001 | J. Biol. Chem. | pmid:11278517 |
El Bawab S et al. | Biochemical characterization of the reverse activity of rat brain ceramidase. A CoA-independent and fumonisin B1-insensitive ceramide synthase. | 2001 | J. Biol. Chem. | pmid:11278489 |
Carlson DB et al. | Fumonisin B1 promotes aflatoxin B1 and N-methyl-N'-nitro-nitrosoguanidine-initiated liver tumors in rainbow trout. | 2001 | Toxicol. Appl. Pharmacol. | pmid:11264020 |
Momany FA and Dombrink-Kurtzman MA | Molecular dynamics simulations on the mycotoxin fumonisin B1. | 2001 | J. Agric. Food Chem. | pmid:11262071 |
Maragos CM et al. | Fluorescence polarization as a means for determination of fumonisins in maize. | 2001 | J. Agric. Food Chem. | pmid:11261998 |
Zhang Y et al. | Identification of differentially expressed genes following treatment of monkey kidney cells with the mycotoxin fumonisin B(1). | 2001 | Food Chem. Toxicol. | pmid:11259850 |
Sharma RP et al. | Decreased fumonisin hepatotoxicity in mice with a targeted deletion of tumor necrosis factor receptor 1. | 2001 | Toxicology | pmid:11250056 |
Jiménez M et al. | Characterization of Gibberella fujikuroi complex isolates by fumonisin B1 and B2 analysis and by RAPD and restriction analysis of PCR-amplified internal transcribed spacers of ribosomal DNA. | 2000 | Syst. Appl. Microbiol. | pmid:11249025 |
Mathur S et al. | Fumonisin B(1) is hepatotoxic and nephrotoxic in milk-fed calves. | 2001 | Toxicol. Sci. | pmid:11248152 |
Mathur S et al. | Fumonisin B(1) increases serum sphinganine concentration but does not alter serum sphingosine concentration or induce cardiovascular changes in milk-fed calves. | 2001 | Toxicol. Sci. | pmid:11248151 |
Gumprecht LA et al. | Species and organ specificity of fumonisin-induced endothelial alterations: potential role in porcine pulmonary edema. | 2001 | Toxicology | pmid:11246126 |
Ziulkoski AL et al. | De novo synthesis and recycling pathways of sphingomyelin in rat Sertoli cells. | 2001 | Biochem. Biophys. Res. Commun. | pmid:11237757 |
van der Westhuizen L et al. | The effect of repeated gavage doses of fumonisin B1 on the sphinganine and sphingosine levels in vervet monkeys. | 2001 | Toxicon | pmid:11223085 |
Mubatanhema W et al. | Prevalence of Fusarium species of the Liseola section on Zimbabwean corn and their ability to produce the mycotoxins zearalenone, moniliformin and fumonisin B1. | 1999 | Mycopathologia | pmid:11189767 |
Lemke SL et al. | Deamination of fumonisin B(1) and biological assessment of reaction product toxicity. | 2001 | Chem. Res. Toxicol. | pmid:11170503 |
Bezombes C et al. | Lysosomal sphingomyelinase is not solicited for apoptosis signaling. | 2001 | FASEB J. | pmid:11156942 |
Nagy B et al. | Fumonisin B1 does not prevent apoptosis in A431 human epidermoid carcinoma cells after photosensitization with a silicon phthalocyanine. | 2000 | J. Photochem. Photobiol. B, Biol. | pmid:11154079 |
Schmidt K et al. | Regulated apical secretion of zymogens in rat pancreas. Involvement of the glycosylphosphatidylinositol-anchored glycoprotein GP-2, the lectin ZG16p, and cholesterol-glycosphingolipid-enriched microdomains. | 2001 | J. Biol. Chem. | pmid:11152672 |
Pocsfalvi G et al. | Interaction of fusarium mycotoxins, fusaproliferin and fumonisin B1, with DNA studied by electrospray ionization mass spectrometry. | 2000 | J. Agric. Food Chem. | pmid:11141251 |
Gutema T et al. | Occurrence of fumonisins and moniliformin in corn and corn-based food products of U.S. origin. | 2000 | J. Food Prot. | pmid:11131899 |
Riley RT et al. | Alteration in sphingolipid metabolism: bioassays for fumonisin- and ISP-I-like activity in tissues, cells and other matrices. | 1999 | Nat. Toxins | pmid:11122537 |
Maragos CM and Thompson VS | Fiber-optic immunosensor for mycotoxins. | 1999 | Nat. Toxins | pmid:11122532 |
Plattner RD | HPLC/MS analysis of fusarium mycotoxins, fumonisins and deoxynivalenol. | 1999 | Nat. Toxins | pmid:11122531 |
Picco M et al. | Aflatoxin B1 and fumosin B1 in mixed cultures of Aspergillus flavus and Fusarium proliferatum on maize. | 1999 | Nat. Toxins | pmid:11122525 |
Buim MR et al. | Immunohistochemistry of fumonisin in poultry using avidin-biotin-peroxidase system. | 1999 | Nat. Toxins | pmid:11122519 |
Fazekas B et al. | Reusability of immunoaffinity columns for determination of fumonisins in maize. | 1999 | Nat. Toxins | pmid:11122516 |
Proctor RH et al. | Biosynthetic and genetic relationships of B-series fumonisins produced by Gibberella fujikuroi mating population A. | 1999 | Nat. Toxins | pmid:11122515 |
Biswal SS et al. | Changes in ceramide and sphingomyelin following fludarabine treatment of human chronic B-cell leukemia cells. | 2000 | Toxicology | pmid:11118669 |
Meli R et al. | Effect of fumonisin B1 on inducible nitric oxide synthase and cyclooxygenase-2 in LPS-stimulated J774A.1 cells. | 2000 | Life Sci. | pmid:11105999 |
Machinski Júnior M and Soares LM | Fumonisins B1 and B2 in Brazilian corn-based food products. | 2000 | Food Addit Contam | pmid:11103273 |
De Jong AJ et al. | Chemical-induced apoptotic cell death in tomato cells: involvement of caspase-like proteases. | 2000 | Planta | pmid:11089678 |
Dombrink-Kurtzman MA et al. | Effect of nixtamalization (Alkaline cooking) on fumonisin-contaminated corn for production of masa and tortillas. | 2000 | J. Agric. Food Chem. | pmid:11087554 |
Desjardins AE and Plattner RD | Fumonisin B(1)-nonproducing strains of Fusarium verticillioides cause maize (Zea mays) ear infection and ear rot. | 2000 | J. Agric. Food Chem. | pmid:11087553 |
Jindal N et al. | Occurrence of fumonisin B1 in maize and poultry feeds in Haryana, India. | 1999 | Mycopathologia | pmid:11086483 |
Jenkins GR et al. | Identification of fumonisin B1 as an inhibitor of argininosuccinate synthetase using fumonisin affinity chromatography and in vitro kinetic studies. | 2000 | J. Biochem. Mol. Toxicol. | pmid:11083085 |
Kpodo K et al. | Fusaria and fumonisins in maize from Ghana and their co-occurrence with aflatoxins. | 2000 | Int. J. Food Microbiol. | pmid:11078165 |
Aranda M et al. | Assessment of in vitro mutagenicity in Salmonella and in vivo genotoxicity in mice of the mycotoxin fumonisin B(1). | 2000 | Mutagenesis | pmid:11076997 |
Van Overmeire I et al. | Synthesis and biological evaluation of ceramide analogues with substituted aromatic rings or an allylic fluoride in the sphingoid moiety. | 2000 | J. Med. Chem. | pmid:11063615 |
Henry MH et al. | The toxicity of purified fumonisin B1 in broiler chicks. | 2000 | Poult. Sci. | pmid:11055840 |
Shephard GS | Liquid chromatographic method for fumonisins in corn. | 2001 | Methods Mol. Biol. | pmid:11051000 |
Wilkes JG and Lay JO | Electrospray mass spectrometry for mycotoxin detection and purity analysis. | 2001 | Methods Mol. Biol. | pmid:11050992 |
Eppley RM | Preparatory isolation of mycotoxins from solid phase fungal cultures. | 2001 | Methods Mol. Biol. | pmid:11050990 |
Asai T et al. | Fumonisin B1-induced cell death in arabidopsis protoplasts requires jasmonate-, ethylene-, and salicylate-dependent signaling pathways. | 2000 | Plant Cell | pmid:11041879 |
Stone JM et al. | Simulation of fungal-mediated cell death by fumonisin B1 and selection of fumonisin B1-resistant (fbr) Arabidopsis mutants. | 2000 | Plant Cell | pmid:11041878 |
Bondy GS et al. | A comparison of clinical, histopathological and cell-cycle markers in rats receiving the fungal toxins fumonisin B1 or fumonisin B2 by intraperitoneal injection. | 2000 | Food Chem. Toxicol. | pmid:11039321 |
Kirkham PA et al. | Ligation of the WC1 receptor induces gamma delta T cell growth arrest through fumonisin B1-sensitive increases in cellular ceramide. | 2000 | J. Immunol. | pmid:11034356 |
Hartl M and Humpf HU | Toxicity assessment of fumonisins using the brine shrimp (Artemia salina) bioassay. | 2000 | Food Chem. Toxicol. | pmid:11033198 |
Caloni F et al. | In vitro metabolism of fumonisin B1 by ruminal microflora. | 2000 | Vet. Res. Commun. | pmid:11014607 |
Dombrink-Kurtzman MA et al. | Activation of rat splenic macrophage and lymphocyte functions by fumonisin B1. | 2000 | Immunopharmacology | pmid:10996037 |
da Silva JB et al. | Mycoflora and occurrence of aflatoxin B(1) and fumonisin B(1) during storage of Brazilian sorghum. | 2000 | J. Agric. Food Chem. | pmid:10995362 |
Zomborszky-Kovács M et al. | Preliminary communication: examination of the harmful effect to fetuses of fumonisin B(1) in pregnant sows. | 2000 | Teratog., Carcinog. Mutagen. | pmid:10992276 |
van der Westhuizen L et al. | The effect of a single gavage dose of fumonisin B(1) on the sphinganine and sphingosine levels in vervet monkeys. | 2001 Feb-Mar | Toxicon | pmid:10978745 |
Kwon OS et al. | Biochemical and morphological effects of fumonisin B(1) on primary cultures of rat cerebrum. | 2000 Jul-Aug | Neurotoxicol Teratol | pmid:10974595 |
Abbas HK et al. | Mycotoxin production by Fusarium proliferatum isolates from rice with Fusarium sheath rot disease. | 1999 | Mycopathologia | pmid:10967968 |
Sharma RP et al. | Fumonisin hepatotoxicity is reduced in mice carrying the human tumour necrosis factor alpha transgene. | 2000 | Arch. Toxicol. | pmid:10959799 |
Velluti A et al. | The effect of fungal competition on colonization of maize grain by Fusarium moniliforme, F. proliferatum and F. graminearum and on fumonisin B1 and zearalenone formation. | 2000 | Int. J. Food Microbiol. | pmid:10946839 |
Preis RA and Vargas EA | A method for determining fumonisin B1 in corn using immunoaffinity column clean-up and thin layer chromatography/densitometry. | 2000 | Food Addit Contam | pmid:10932789 |
Enongene EN et al. | Disruption of sphingolipid metabolism in small intestines, liver and kidney of mice dosed subcutaneously with fumonisin B(1). | 2000 | Food Chem. Toxicol. | pmid:10930700 |
Ramljak D et al. | A potential mechanism for fumonisin B(1)-mediated hepatocarcinogenesis: cyclin D1 stabilization associated with activation of Akt and inhibition of GSK-3beta activity. | 2000 | Carcinogenesis | pmid:10910956 |
Suzuki A and Tsutomi Y | Inductions of fibroblast-like morphology and high growth activity by low-dose CPT-11 in PC12 cells: role of tenascin. | 2000 | Toxicol In Vitro | pmid:10906440 |
Wang H et al. | The fumonisin B1 content in corn from North China, a high-risk area of esophageal cancer. | 2000 | J. Environ. Pathol. Toxicol. Oncol. | pmid:10905519 |
Medina-MartÃnez MS and MartÃnez AJ | Mold occurrence and aflatoxin B(1) and fumonisin B(1) determination in corn samples in Venezuela. | 2000 | J. Agric. Food Chem. | pmid:10898632 |
Barna-Vetró I et al. | Development of a sensitive ELISA for the determination of fumonisin B(1) in cereals. | 2000 | J. Agric. Food Chem. | pmid:10898629 |
Li YC et al. | The individual and combined effects of fumonisin B1 and moniliformin on performance and selected immune parameters in turkey poults. | 2000 | Poult. Sci. | pmid:10875770 |
Lawrence JF et al. | Effect of temperature and solvent composition on extraction of fumonisins B1 and B2 from corn products. | 2000 May-Jun | J AOAC Int | pmid:10868583 |
Lawrence JF et al. | Evaluation of silica- and sepharose-based immunoaffinity sorbents for sample cleanup in determination of fumonisins B1 and B2 in corn products. | 2000 May-Jun | J AOAC Int | pmid:10868582 |
Zomborszky MK et al. | Experiment to determine limits of tolerance for fumonisin B1 in weaned piglets. | 2000 | J. Vet. Med. B Infect. Dis. Vet. Public Health | pmid:10861196 |
Mobio TA et al. | Prevention by vitamin E of DNA fragmentation and apoptosis induced by fumonisin B1 in C6 glioma cells. | 2000 | Arch. Toxicol. | pmid:10839479 |
Shephard GS et al. | Natural occurrence of fumonisins in corn from Iran. | 2000 | J. Agric. Food Chem. | pmid:10820105 |
Moon WS et al. | Early ultrastructural changes of apoptosis induced by fumonisin B1 in rat liver. | 2000 | Yonsei Med. J. | pmid:10817019 |
Takasaki M et al. | Cancer chemopreventive activity of euglobal-G1 from leaves of Eucalyptus grandis. | 2000 | Cancer Lett. | pmid:10814880 |