fumonisin b1
fumonisin b1 is a lipid of Sphingolipids (SP) class. Fumonisin b1 is associated with abnormalities such as Infection, Kidney Diseases, Liver diseases, DERMATITIS HERPETIFORMIS, FAMILIAL and Malnutrition. The involved functions are known as Gene Expression, Anabolism, Signal, Biosynthetic Pathways and Regulation. Fumonisin b1 often locates in Body tissue, Microsomes, microsomal membrane, Protoplasm and Mitochondria. The associated genes with fumonisin b1 are Genome, P4HTM gene, FATE1 gene, BCL2 gene and TMEM132D gene. The related lipids are dihydroceramide, ceramide 1-phosphate, Sphingolipids, Fatty Acids and Palmitates.
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Introduction
To understand associated biological information of fumonisin b1, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with fumonisin b1?
fumonisin b1 is suspected in Infection, Kidney Diseases, Liver diseases, DERMATITIS HERPETIFORMIS, FAMILIAL, Malnutrition, Celiac Disease and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with fumonisin b1
PubChem Associated disorders and diseases
What pathways are associated with fumonisin b1
Lipid pathways are not clear in current pathway databases. We organized associated pathways with fumonisin b1 through full-text articles, including metabolic pathways or pathways of biological mechanisms.
Related references are published most in these journals:
| Pathway name | Related literatures |
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PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with fumonisin b1?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
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What functions are associated with fumonisin b1?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
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What lipids are associated with fumonisin b1?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
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What genes are associated with fumonisin b1?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
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What common seen animal models are associated with fumonisin b1?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with fumonisin b1
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Broomhead JN et al. | Chronic effects of fumonisin B1 in broilers and turkeys fed dietary treatments to market age. | 2002 | Poult. Sci. | pmid:11885900 |
| Vesonder RF and Wu W | Correlation of moniliformin, but not fumonisin B1 levels, in culture materials of Fusarium isolates to acute death in ducklings. | 1998 | Poult. Sci. | pmid:9469753 |
| Henry MH and Wyatt RD | The toxicity of fumonisin B1, B2, and B3, individually and in combination, in chicken embryos. | 2001 | Poult. Sci. | pmid:11297276 |
| Siloto EV et al. | Lipid metabolism of commercial layers fed diets containing aflatoxin, fumonisin, and a binder. | 2013 | Poult. Sci. | pmid:23873555 |
| Rossi F et al. | Effect of Bt corn on broiler growth performance and fate of feed-derived DNA in the digestive tract. | 2005 | Poult. Sci. | pmid:16050119 |
| Weibking TS et al. | Individual and combined effects of feeding Fusarium moniliforme culture material, containing known levels of fumonisin B1, and aflatoxin B1 in the young turkey poult. | 1994 | Poult. Sci. | pmid:7816726 |
| Miazzo R et al. | Efficacy of sodium bentonite as a detoxifier of broiler feed contaminated with aflatoxin and fumonisin. | 2005 | Poult. Sci. | pmid:15685935 |
| Henry MH et al. | The toxicity of purified fumonisin B1 in broiler chicks. | 2000 | Poult. Sci. | pmid:11055840 |
| Ledoux DR et al. | Effects of feeding Fusarium moniliforme culture material, containing known levels of fumonisin B1, in the young turkey poult. | 1996 | Poult. Sci. | pmid:9000269 |
| Keck BB and Bodine AB | The effects of fumonisin B1 on viability and mitogenic response of avian immune cells. | 2006 | Poult. Sci. | pmid:16776470 |
| Asrani RK et al. | Effects of feeding Fusarium verticillioides (formerly Fusarium moniliforme) culture material containing known levels of fumonisin B1 in Japanese quail (Coturnix coturnix japonica). | 2006 | Poult. Sci. | pmid:16830851 |
| Del Bianchi M et al. | Effects of prolonged oral administration of aflatoxin B1 and fumonisin B1 in broiler chickens. | 2005 | Poult. Sci. | pmid:16479938 |
| Tardieu D et al. | Toxicity of maize containing known levels of fumonisin B1 during force-feeding of ducks. | 2004 | Poult. Sci. | pmid:15339002 |
| Qureshi MA and Hagler WM | Effect of fumonisin-B1 exposure on chicken macrophage functions in vitro. | 1992 | Poult. Sci. | pmid:1539010 |
| Kubena LF et al. | Individual and combined effects of fumonisin B1 present in Fusarium moniliforme culture material and diacetoxyscirpenol or ochratoxin A in turkey poults. | 1997 | Poult. Sci. | pmid:9057204 |
| Sharma D et al. | Individual and combined effects of fumonisin b1 and moniliformin on clinicopathological and cell-mediated immune response in Japanese quail. | 2008 | Poult. Sci. | pmid:18492990 |
| Kubena LF et al. | Individual and combined effects of fumonisin B1 present in Fusarium moniliforme culture material and T-2 toxin or deoxynivalenol in broiler chicks. | 1997 | Poult. Sci. | pmid:9276886 |
| Kubena LF et al. | Effects of long-term feeding of diets containing moniliformin, supplied by Fusarium fujikuroi culture material, and fumonisin, supplied by Fusarium moniliforme culture material, to laying hens. | 1999 | Poult. Sci. | pmid:10560820 |
| Kubena LF et al. | Influence of fumonisin B1, present in Fusarium moniliforme culture material, and T-2 toxin on turkey poults. | 1995 | Poult. Sci. | pmid:7724453 |
| Li YC et al. | Effects of fumonisin B1 on selected immune responses in broiler chicks. | 1999 | Poult. Sci. | pmid:10515357 |
| Tran ST et al. | Chronic effects of fumonisin B1 on ducks. | 2005 | Poult. Sci. | pmid:15685938 |
| Li YC et al. | The individual and combined effects of fumonisin B1 and moniliformin on performance and selected immune parameters in turkey poults. | 2000 | Poult. Sci. | pmid:10875770 |
| Weibking TS et al. | Effects of feeding Fusarium moniliforme culture material, containing known levels of fumonisin B1, on the young broiler chick. | 1993 | Poult. Sci. | pmid:8464788 |
| Ogido R et al. | Effects of prolonged administration of aflatoxin B1 and fumonisin B1 in laying Japanese quail. | 2004 | Poult. Sci. | pmid:15615006 |
| Rauber RH et al. | Individual and combined effects of Salmonella typhimurium lipopolysaccharide and fumonisin B1 in broiler chickens. | 2012 | Poult. Sci. | pmid:23091133 |
| Kubena LF et al. | Effects of feeding fumonisin B1 present in Fusarium moniliforme culture material and aflatoxin singly and in combination to turkey poults. | 1995 | Poult. Sci. | pmid:7479507 |
| Wu W et al. | The effect of fumonisin B1 on isolated chondrocytes and on bone formation. | 1995 | Poult. Sci. | pmid:7501587 |
| Liao YJ et al. | Inhibition of fumonisin B1 cytotoxicity by nanosilicate platelets during mouse embryo development. | 2014 | PLoS ONE | pmid:25383881 |
| He S et al. | The LSD1-interacting protein GILP is a LITAF domain protein that negatively regulates hypersensitive cell death in Arabidopsis. | 2011 | PLoS ONE | pmid:21526181 |
| Kacprzyk J et al. | The root hair assay facilitates the use of genetic and pharmacological tools in order to dissect multiple signalling pathways that lead to programmed cell death. | 2014 | PLoS ONE | pmid:24755572 |
| Lee H et al. | Mitochondrial ceramide-rich macrodomains functionalize Bax upon irradiation. | 2011 | PLoS ONE | pmid:21695182 |
| Malapi-Wight M et al. | Sda1, a Cys2-His2 zinc finger transcription factor, is involved in polyol metabolism and fumonisin B1 production in Fusarium verticillioides. | 2013 | PLoS ONE | pmid:23844049 |
| Czembor E et al. | Effect of Environmental Factors on Fusarium Species and Associated Mycotoxins in Maize Grain Grown in Poland. | 2015 | PLoS ONE | pmid:26225823 |
| Agostini F et al. | Prion protein accumulation in lipid rafts of mouse aging brain. | 2013 | PLoS ONE | pmid:24040215 |
| Igarashi D et al. | Pattern-triggered immunity suppresses programmed cell death triggered by fumonisin b1. | 2013 | PLoS ONE | pmid:23560104 |
| Shin KO et al. | Terpene alcohols inhibit de novo sphingolipid biosynthesis. | 2012 | Planta Med. | pmid:22274813 |
| Gutiérrez-Nájera N et al. | Fumonisin B1, a sphingoid toxin, is a potent inhibitor of the plasma membrane H+-ATPase. | 2005 | Planta | pmid:15703925 |
| Sánchez-Rangel D et al. | Fumonisin B1, a toxin produced by Fusarium verticillioides, modulates maize β-1,3-glucanase activities involved in defense response. | 2012 | Planta | pmid:22120123 |
| De Jong AJ et al. | Chemical-induced apoptotic cell death in tomato cells: involvement of caspase-like proteases. | 2000 | Planta | pmid:11089678 |
| Lenz HD et al. | ATG7 contributes to plant basal immunity towards fungal infection. | 2011 | Plant Signal Behav | pmid:21617379 |
| Saucedo-GarcÃa M et al. | Reactive oxygen species as transducers of sphinganine-mediated cell death pathway. | 2011 | Plant Signal Behav | pmid:21921699 |
| Qin X et al. | Sphingosine kinase AtSPHK1 functions in fumonisin B1-triggered cell death in Arabidopsis. | 2017 | Plant Physiol. Biochem. | pmid:28846870 |
| Luttgeharm KD et al. | Overexpression of Arabidopsis Ceramide Synthases Differentially Affects Growth, Sphingolipid Metabolism, Programmed Cell Death, and Mycotoxin Resistance. | 2015 | Plant Physiol. | pmid:26276842 |
| Feng H et al. | Functional characterization of the Arabidopsis eukaryotic translation initiation factor 5A-2 that plays a crucial role in plant growth and development by regulating cell division, cell growth, and cell death. | 2007 | Plant Physiol. | pmid:17513484 |
| Zhao Y et al. | Classic myrosinase-dependent degradation of indole glucosinolate attenuates fumonisin B1-induced programmed cell death in Arabidopsis. | 2015 | Plant J. | pmid:25645692 |
| Stone JM et al. | Arabidopsis AtSPL14, a plant-specific SBP-domain transcription factor, participates in plant development and sensitivity to fumonisin B1. | 2005 | Plant J. | pmid:15703061 |
| Bindschedler LV et al. | Peroxidase-dependent apoplastic oxidative burst in Arabidopsis required for pathogen resistance. | 2006 | Plant J. | pmid:16889645 |
| Watanabe N and Lam E | Arabidopsis Bax inhibitor-1 functions as an attenuator of biotic and abiotic types of cell death. | 2006 | Plant J. | pmid:16507080 |
| Aubert A et al. | Sphingolipids involvement in plant endomembrane differentiation: the BY2 case. | 2011 | Plant J. | pmid:21205030 |
| Lin SS et al. | RING1 E3 ligase localizes to plasma membrane lipid rafts to trigger FB1-induced programmed cell death in Arabidopsis. | 2008 | Plant J. | pmid:18643987 |
| Lenz HD et al. | Autophagy differentially controls plant basal immunity to biotrophic and necrotrophic pathogens. | 2011 | Plant J. | pmid:21332848 |
| Basnayake BM et al. | Arabidopsis DAL1 and DAL2, two RING finger proteins homologous to Drosophila DIAP1, are involved in regulation of programmed cell death. | 2011 | Plant Cell Rep. | pmid:20972793 |
| Markham JE et al. | Sphingolipids containing very-long-chain fatty acids define a secretory pathway for specific polar plasma membrane protein targeting in Arabidopsis. | 2011 | Plant Cell | pmid:21666002 |
| Chivasa S et al. | Extracellular ATP functions as an endogenous external metabolite regulating plant cell viability. | 2005 | Plant Cell | pmid:16199612 |
| Asai T et al. | Fumonisin B1-induced cell death in arabidopsis protoplasts requires jasmonate-, ethylene-, and salicylate-dependent signaling pathways. | 2000 | Plant Cell | pmid:11041879 |
| Kimberlin AN et al. | Arabidopsis 56-amino acid serine palmitoyltransferase-interacting proteins stimulate sphingolipid synthesis, are essential, and affect mycotoxin sensitivity. | 2013 | Plant Cell | pmid:24214397 |
| Stone JM et al. | Simulation of fungal-mediated cell death by fumonisin B1 and selection of fumonisin B1-resistant (fbr) Arabidopsis mutants. | 2000 | Plant Cell | pmid:11041878 |
| Arias SL et al. | Toxin distribution and sphingoid base imbalances in Fusarium verticillioides-infected and fumonisin B1-watered maize seedlings. | 2016 | Phytochemistry | pmid:26903312 |
| Abbas HK et al. | Biological activities of synthetic analogues of Alternaria alternata toxin (AAL-toxin) and fumonisin in plant and mammalian cell cultures. | 1995 | Phytochemistry | pmid:8590636 |
| Desjardins AE et al. | Identification and heritability of fumonisin insensitivity in Zea mays. | 2005 | Phytochemistry | pmid:16198380 |
| Szabó A et al. | Oral administration of fumonisin B and T-2 individually and in combination affects hepatic total and mitochondrial membrane lipid profile of rabbits. | 2016 | Physiol Int | pmid:28229635 |
| Boppana NB et al. | Ceramide synthase inhibitor fumonisin B1 inhibits apoptotic cell death in SCC17B human head and neck squamous carcinoma cells after Pc4 photosensitization. | 2014 | Photochem. Photobiol. Sci. | pmid:25266739 |
| He Q et al. | Pharmacological antagonism of fumonisin B1 cytotoxicity in porcine renal epithelial cells (LLC-PK1): a model for reducing fumonisin-induced nephrotoxicity in vivo. | 2002 | Pharmacol. Toxicol. | pmid:12076308 |
| Dutton MF | Fumonisins, mycotoxins of increasing importance: their nature and their effects. | 1996 | Pharmacol. Ther. | pmid:8843466 |
| Atroshi F et al. | Fumonisin B1-induced DNA damage in rat liver and spleen: effects of pretreatment with coenzyme Q10, L-carnitine, alpha-tocopherol and selenium. | 1999 | Pharmacol. Res. | pmid:10660942 |
| Atroshi F et al. | Effects of tamoxifen, melatonin, coenzyme Q10, and L-carnitine supplementation on bacterial growth in the presence of mycotoxins. | 1998 | Pharmacol. Res. | pmid:9774492 |
| Eichele K et al. | R(+)-methanandamide-induced apoptosis of human cervical carcinoma cells involves a cyclooxygenase-2-dependent pathway. | 2009 | Pharm. Res. | pmid:19015962 |
| Demirel G et al. | Role of fumonisin B1 on DNA methylation changes in rat kidney and liver cells. | 2015 | Pharm Biol | pmid:25858139 |
| Mazzoni E et al. | Field control of Fusarium ear rot, Ostrinia nubilalis (Hübner), and fumonisins in maize kernels. | 2011 | Pest Manag. Sci. | pmid:21394878 |
| Nogueira TC et al. | Involvement of phosphatidylinositol-3 kinase/AKT/PKCzeta/lambda pathway in the effect of palmitate on glucose-induced insulin secretion. | 2008 | Pancreas | pmid:18815554 |
| Hwang D et al. | Effects of ceramide inhibition on experimental radiation-induced oral mucositis. | 2005 | Oral Surg Oral Med Oral Pathol Oral Radiol Endod | pmid:16122660 |
| Kellerman TS et al. | Leukoencephalomalacia in two horses induced by oral dosing of fumonisin B1. | 1990 | Onderstepoort J. Vet. Res. | pmid:2293136 |
| Marasas WF et al. | Leukoencephalomalacia in a horse induced by fumonisin B1 isolated from Fusarium moniliforme. | 1988 | Onderstepoort J. Vet. Res. | pmid:3217091 |
| White-Gilbertson S et al. | Ceramide synthase 6 modulates TRAIL sensitivity and nuclear translocation of active caspase-3 in colon cancer cells. | 2009 | Oncogene | pmid:19137010 |
| Wolf G | Inhibition of cellular uptake of folate by blocking synthesis of the membrane folate receptor. | 1998 | Nutr. Rev. | pmid:9564182 |
| Wolf G | Mechanism of the mitogenic and carcinogenic action of fumonisin B1, a mycotoxin. | 1994 | Nutr. Rev. | pmid:8090377 |
| Saucedo-GarcÃa M et al. | MPK6, sphinganine and the LCB2a gene from serine palmitoyltransferase are required in the signaling pathway that mediates cell death induced by long chain bases in Arabidopsis. | 2011 | New Phytol. | pmid:21534970 |
| Osuchowski MF et al. | Fumonisin B1-induced neurodegeneration in mice after intracerebroventricular infusion is concurrent with disruption of sphingolipid metabolism and activation of proinflammatory signaling. | 2005 | Neurotoxicology | pmid:15713342 |
| Osuchowski MF and Sharma RP | Fumonisin B1 induces necrotic cell death in BV-2 cells and murine cultured astrocytes and is antiproliferative in BV-2 cells while N2A cells and primary cortical neurons are resistant. | 2005 | Neurotoxicology | pmid:16005069 |
| Ferguson SA et al. | Prenatal fumonisin (FB1) treatment in rats results in minimal maternal or offspring toxicity. | 1997 | Neurotoxicology | pmid:9291504 |
| Monnet-Tschudi F et al. | The naturally occurring food mycotoxin fumonisin B1 impairs myelin formation in aggregating brain cell culture. | 1999 | Neurotoxicology | pmid:10091857 |
| Kwon OS et al. | Biochemical and morphological effects of fumonisin B(1) on primary cultures of rat cerebrum. | 2000 Jul-Aug | Neurotoxicol Teratol | pmid:10974595 |
| Kwon OS et al. | Effects of fumonisin B1 treatment on blood-brain barrier transfer in developing rats. | 1997 Mar-Apr | Neurotoxicol Teratol | pmid:9136132 |
| Poersch AB et al. | Fumonisin B1 facilitates seizures induced by pentylenetetrazol in mice. | Neurotoxicol Teratol | pmid:26342287 | |
| Domijan AM et al. | Impact of fumonisin B1 on glutamate toxicity and low magnesium-induced seizure activity in neuronal primary culture. | 2012 | Neuroscience | pmid:22178271 |
| Yang MS et al. | Sphingomyelinase but not ceramide induces nitric oxide synthase expression in rat brain microglia. | 2001 | Neurosci. Lett. | pmid:11567796 |
| Plo I et al. | Involvement of de novo ceramide biosynthesis in lymphotoxin-induced oligodendrocyte death. | 1999 | Neuroreport | pmid:10439466 |
| Callihan P et al. | Distinct generation, pharmacology, and distribution of sphingosine 1-phosphate and dihydrosphingosine 1-phosphate in human neural progenitor cells. | 2012 | Neuropharmacology | pmid:22016110 |
| Galvano F et al. | DNA damage in astrocytes exposed to fumonisin B1. | 2002 | Neurochem. Res. | pmid:11958538 |
| Toxicology and carcinogenesis studies of fumonisin B1 (cas no. 116355-83-0) in F344/N rats and B6C3F1 mice (feed studies). | 2001 | Natl Toxicol Program Tech Rep Ser | pmid:11852482 | |
| Li FQ et al. | Mycotoxins (trichothecenes, zearalenone and fumonisins) in cereals associated with human red-mold intoxications stored since 1989 and 1991 in China. | 1999 | Nat. Toxins | pmid:10647510 |
| Wild CP et al. | Absence of a synergistic effect between fumonisin B1 and N-nitrosomethylbenzylamine in the induction of oesophageal papillomas in the rat. | 1997 | Nat. Toxins | pmid:9285918 |
| Prelusky DB et al. | Pharmacokinetic fate of 14C-labelled fumonisin B1 in swine. | 1994 | Nat. Toxins | pmid:8075896 |
| Vudathala DK et al. | Pharmacokinetic fate and pathological effects of 14C-fumonisin B1 in laying hens. | 1994 | Nat. Toxins | pmid:8075897 |
| Proctor RH et al. | Biosynthetic and genetic relationships of B-series fumonisins produced by Gibberella fujikuroi mating population A. | 1999 | Nat. Toxins | pmid:11122515 |
| Fazekas B et al. | Reusability of immunoaffinity columns for determination of fumonisins in maize. | 1999 | Nat. Toxins | pmid:11122516 |
| Buim MR et al. | Immunohistochemistry of fumonisin in poultry using avidin-biotin-peroxidase system. | 1999 | Nat. Toxins | pmid:11122519 |
| Riley RT et al. | Evidence for disruption of sphingolipid metabolism as a contributing factor in the toxicity and carcinogenicity of fumonisins. | 1996 | Nat. Toxins | pmid:8680751 |
| Lim CW et al. | Intravenous fumonisin B1 induces cell proliferation and apoptosis in the rat. | 1996 | Nat. Toxins | pmid:8680752 |
| Bucci TJ et al. | Leukoencephalomalacia and hemorrhage in the brain of rabbits gavaged with mycotoxin fumonisin B1. | 1996 | Nat. Toxins | pmid:8680754 |