fumonisin b1

fumonisin b1 is a lipid of Sphingolipids (SP) class. Fumonisin b1 is associated with abnormalities such as Infection, Kidney Diseases, Liver diseases, DERMATITIS HERPETIFORMIS, FAMILIAL and Malnutrition. The involved functions are known as Gene Expression, Anabolism, Signal, Biosynthetic Pathways and Regulation. Fumonisin b1 often locates in Body tissue, Microsomes, microsomal membrane, Protoplasm and Mitochondria. The associated genes with fumonisin b1 are Genome, P4HTM gene, FATE1 gene, BCL2 gene and TMEM132D gene. The related lipids are dihydroceramide, ceramide 1-phosphate, Sphingolipids, Fatty Acids and Palmitates.

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Introduction

To understand associated biological information of fumonisin b1, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with fumonisin b1?

fumonisin b1 is suspected in Infection, Kidney Diseases, Liver diseases, DERMATITIS HERPETIFORMIS, FAMILIAL, Malnutrition, Celiac Disease and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with fumonisin b1

MeSH term MeSH ID Detail
Stomach Ulcer D013276 75 associated lipids
Neuroblastoma D009447 66 associated lipids
Leukemia, Myeloid D007951 52 associated lipids
Asthma D001249 52 associated lipids
Precancerous Conditions D011230 48 associated lipids
Fatty Liver D005234 48 associated lipids
Liver Neoplasms, Experimental D008114 46 associated lipids
Adenoma D000236 40 associated lipids
Chemical and Drug Induced Liver Injury D056486 39 associated lipids
Lung Diseases D008171 37 associated lipids
Per page 10 20 50 100 | Total 54

PubChem Associated disorders and diseases

What pathways are associated with fumonisin b1

Lipid pathways are not clear in current pathway databases. We organized associated pathways with fumonisin b1 through full-text articles, including metabolic pathways or pathways of biological mechanisms.

Related references are published most in these journals:

Pathway name Related literatures
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PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with fumonisin b1?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with fumonisin b1?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with fumonisin b1?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with fumonisin b1?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with fumonisin b1?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with fumonisin b1

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Per page 10 20 50 100 | Total 1278
Authors Title Published Journal PubMed Link
Pinelli E et al. Activation of mitogen-activated protein kinase by fumonisin B(1) stimulates cPLA(2) phosphorylation, the arachidonic acid cascade and cAMP production. 1999 Carcinogenesis pmid:10469611
Williamson LC et al. Neuronal sensitivity to tetanus toxin requires gangliosides. 1999 J. Biol. Chem. pmid:10455200
Spinedi A et al. Ceramide accumulation precedes caspase-dependent apoptosis in CHP-100 neuroepithelioma cells exposed to the protein phosphatase inhibitor okadaic acid. 1999 Cell Death Differ. pmid:10453072
Blackwell BA et al. Oxidative deamination of hydrolyzed fumonisin B(1) (AP(1)) by cultures of Exophiala spinifera. 1999 Nat. Toxins pmid:10441035
Plo I et al. Involvement of de novo ceramide biosynthesis in lymphotoxin-induced oligodendrocyte death. 1999 Neuroreport pmid:10439466
Shim WB and Woloshuk CP Nitrogen repression of fumonisin B1 biosynthesis in Gibberella fujikuroi. 1999 FEMS Microbiol. Lett. pmid:10436928
Gurung NK et al. In vitro ruminal disappearance of fumonisin B1 and its effects on in vitro dry matter disappearance. 1999 Vet Hum Toxicol pmid:10434370
Chulze SN et al. Fumonisin production on irradiated corn kernels: effect of inoculum size. 1999 J. Food Prot. pmid:10419280
Castellá G et al. Fumonisin production by Fusarium species isolated from cereals and feeds in Spain. 1999 J. Food Prot. pmid:10419279
Alessenko AV and Khrenov AV Role of sphingosine in induced apoptosis. 1999 Lipids pmid:10419095
Turner PC et al. Fumonisin contamination of food: progress in development of biomarkers to better assess human health risks. 1999 Mutat. Res. pmid:10415433
Proctor RH et al. A polyketide synthase gene required for biosynthesis of fumonisin mycotoxins in Gibberella fujikuroi mating population A. 1999 Fungal Genet. Biol. pmid:10413619
Van Overmeire I et al. Effect of aromatic short-chain analogues of ceramide on axonal growth in hippocampal neurons. 1999 J. Med. Chem. pmid:10411490
Takasaki M et al. Anti-carcinogenic activity of Taraxacum plant. I. 1999 Biol. Pharm. Bull. pmid:10408234
Warfield CY and Gilchrist DG Influence of kernel age on fumonisin B1 production in maize by Fusarium moniliforme. 1999 Appl. Environ. Microbiol. pmid:10388675
Kononenko GP et al. [Application of competitive immunoenzyme assay for analysis of group B fumonisins]. 1999 Mar-Apr Prikl. Biokhim. Mikrobiol. pmid:10368851
Liao WC et al. Ataxia telangiectasia-mutated gene product inhibits DNA damage-induced apoptosis via ceramide synthase. 1999 J. Biol. Chem. pmid:10364237
Baker DC and Rottinghaus GE Chronic experimental fumonisin intoxication of calves. 1999 J. Vet. Diagn. Invest. pmid:10353364
Lemmer ER et al. Histopathology and gene expression changes in rat liver during feeding of fumonisin B1, a carcinogenic mycotoxin produced by Fusarium moniliforme. 1999 Carcinogenesis pmid:10334199
Tonnetti L et al. A role for neutral sphingomyelinase-mediated ceramide production in T cell receptor-induced apoptosis and mitogen-activated protein kinase-mediated signal transduction. 1999 J. Exp. Med. pmid:10330437
Ginis I et al. TNF-alpha pretreatment prevents subsequent activation of cultured brain cells with TNF-alpha and hypoxia via ceramide. 1999 Am. J. Physiol. pmid:10329967
Zhang Y et al. The mycotoxin fumonisin B1 transcriptionally activates the p21 promoter through a cis-acting element containing two Sp1 binding sites. 1999 J. Biol. Chem. pmid:10212208
Charoenpornsook K et al. The effects of four mycotoxins on the mitogen stimulated proliferation of bovine peripheral blood mononuclear cells in vitro. 1998 Mycopathologia pmid:10205890
Abeywickrama K et al. Effects of Fusarium moniliforme culture extracts and fumonisin B1 on DNA, RNA and protein synthesis by baby hamster kidney cells. 1998 Mycopathologia pmid:10205886
Gamen S et al. Caspases are the main executioners of Fas-mediated apoptosis, irrespective of the ceramide signalling pathway. 1998 Cell Death Differ. pmid:10200470
Tolleson WH et al. Fumonisin B1 induces apoptosis in cultured human keratinocytes through sphinganine accumulation and ceramide depletion. 1999 Int. J. Oncol. pmid:10200332
Monnet-Tschudi F et al. The naturally occurring food mycotoxin fumonisin B1 impairs myelin formation in aggregating brain cell culture. 1999 Neurotoxicology pmid:10091857
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