fumonisin b1

fumonisin b1 is a lipid of Sphingolipids (SP) class. Fumonisin b1 is associated with abnormalities such as Infection, Kidney Diseases, Liver diseases, DERMATITIS HERPETIFORMIS, FAMILIAL and Malnutrition. The involved functions are known as Gene Expression, Anabolism, Signal, Biosynthetic Pathways and Regulation. Fumonisin b1 often locates in Body tissue, Microsomes, microsomal membrane, Protoplasm and Mitochondria. The associated genes with fumonisin b1 are Genome, P4HTM gene, FATE1 gene, BCL2 gene and TMEM132D gene. The related lipids are dihydroceramide, ceramide 1-phosphate, Sphingolipids, Fatty Acids and Palmitates.

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Introduction

To understand associated biological information of fumonisin b1, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with fumonisin b1?

fumonisin b1 is suspected in Infection, Kidney Diseases, Liver diseases, DERMATITIS HERPETIFORMIS, FAMILIAL, Malnutrition, Celiac Disease and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with fumonisin b1

MeSH term MeSH ID Detail
Inflammation D007249 119 associated lipids
Kidney Diseases D007674 29 associated lipids
Kidney Neoplasms D007680 29 associated lipids
Leukemia, Myeloid D007951 52 associated lipids
Liver Cirrhosis, Experimental D008106 36 associated lipids
Liver Neoplasms, Experimental D008114 46 associated lipids
Lung Diseases D008171 37 associated lipids
Lung Neoplasms D008175 171 associated lipids
Magnesium Deficiency D008275 9 associated lipids
Mycoses D009181 18 associated lipids
Nervous System Diseases D009422 37 associated lipids
Neural Tube Defects D009436 5 associated lipids
Neuroblastoma D009447 66 associated lipids
Neuronal Ceroid-Lipofuscinoses D009472 5 associated lipids
Paralysis D010243 4 associated lipids
Pasteurella Infections D010326 8 associated lipids
Poultry Diseases D011201 21 associated lipids
Precancerous Conditions D011230 48 associated lipids
Prostatic Neoplasms D011471 126 associated lipids
Pseudorabies D011557 1 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with fumonisin b1

Lipid pathways are not clear in current pathway databases. We organized associated pathways with fumonisin b1 through full-text articles, including metabolic pathways or pathways of biological mechanisms.

Related references are published most in these journals:

Pathway name Related literatures
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PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with fumonisin b1?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with fumonisin b1?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with fumonisin b1?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with fumonisin b1?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with fumonisin b1?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with fumonisin b1

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Per page 10 20 50 100 | Total 1278
Authors Title Published Journal PubMed Link
Yeung JM et al. Fumonisin B1 induces protein kinase C translocation via direct interaction with diacylglycerol binding site. 1996 Toxicol. Appl. Pharmacol. pmid:8917690
Martinez-Larrañaga MR et al. Induction of cytochrome P4501A1 and P4504A1 activities and peroxisomal proliferation by fumonisin B1. 1996 Toxicol. Appl. Pharmacol. pmid:8917691
Howard PC et al. Comparison of the toxicity of several fumonisin derivatives in a 28-day feeding study with female B6C3F(1) mice. 2002 Toxicol. Appl. Pharmacol. pmid:12498732
Ramasamy S et al. Fumonisin B1 alters sphingolipid metabolism and disrupts the barrier function of endothelial cells in culture. 1995 Toxicol. Appl. Pharmacol. pmid:7645031
Riley RT et al. Alteration of tissue and serum sphinganine to sphingosine ratio: an early biomarker of exposure to fumonisin-containing feeds in pigs. 1993 Toxicol. Appl. Pharmacol. pmid:8430417
Constable PD et al. Ingestion of fumonisin B1-containing culture material decreases cardiac contractility and mechanical efficiency in swine. 2000 Toxicol. Appl. Pharmacol. pmid:10652243
Mobio TA et al. Epigenetic properties of fumonisin B(1): cell cycle arrest and DNA base modification in C6 glioma cells. 2000 Toxicol. Appl. Pharmacol. pmid:10739748
Gardner NM et al. Elevated nuclear sphingoid base-1-phosphates and decreased histone deacetylase activity after fumonisin B1 treatment in mouse embryonic fibroblasts. 2016 Toxicol. Appl. Pharmacol. pmid:26905748
Carlson DB et al. Fumonisin B1 promotes aflatoxin B1 and N-methyl-N'-nitro-nitrosoguanidine-initiated liver tumors in rainbow trout. 2001 Toxicol. Appl. Pharmacol. pmid:11264020
Bucci TJ et al. Renal effects of fumonisin mycotoxins in animals. 1998 Jan-Feb Toxicol Pathol pmid:9502399