fumonisin b1

fumonisin b1 is a lipid of Sphingolipids (SP) class. Fumonisin b1 is associated with abnormalities such as Infection, Kidney Diseases, Liver diseases, DERMATITIS HERPETIFORMIS, FAMILIAL and Malnutrition. The involved functions are known as Gene Expression, Anabolism, Signal, Biosynthetic Pathways and Regulation. Fumonisin b1 often locates in Body tissue, Microsomes, microsomal membrane, Protoplasm and Mitochondria. The associated genes with fumonisin b1 are Genome, P4HTM gene, FATE1 gene, BCL2 gene and TMEM132D gene. The related lipids are dihydroceramide, ceramide 1-phosphate, Sphingolipids, Fatty Acids and Palmitates.

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Introduction

To understand associated biological information of fumonisin b1, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with fumonisin b1?

fumonisin b1 is suspected in Infection, Kidney Diseases, Liver diseases, DERMATITIS HERPETIFORMIS, FAMILIAL, Malnutrition, Celiac Disease and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with fumonisin b1

MeSH term MeSH ID Detail
Neuronal Ceroid-Lipofuscinoses D009472 5 associated lipids
Neuroblastoma D009447 66 associated lipids
Neural Tube Defects D009436 5 associated lipids
Nervous System Diseases D009422 37 associated lipids
Mycoses D009181 18 associated lipids
Magnesium Deficiency D008275 9 associated lipids
Lung Neoplasms D008175 171 associated lipids
Lung Diseases D008171 37 associated lipids
Liver Neoplasms, Experimental D008114 46 associated lipids
Liver Cirrhosis, Experimental D008106 36 associated lipids
Leukemia, Myeloid D007951 52 associated lipids
Kidney Neoplasms D007680 29 associated lipids
Kidney Diseases D007674 29 associated lipids
Inflammation D007249 119 associated lipids
Hyperplasia D006965 34 associated lipids
Hydrocephalus D006849 6 associated lipids
Carcinoma, Hepatocellular D006528 140 associated lipids
Glioma D005910 112 associated lipids
Glioblastoma D005909 27 associated lipids
Gaucher Disease D005776 13 associated lipids
Per page 10 20 50 100 | Total 54

PubChem Associated disorders and diseases

What pathways are associated with fumonisin b1

Lipid pathways are not clear in current pathway databases. We organized associated pathways with fumonisin b1 through full-text articles, including metabolic pathways or pathways of biological mechanisms.

Related references are published most in these journals:

Pathway name Related literatures
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PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with fumonisin b1?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with fumonisin b1?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with fumonisin b1?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with fumonisin b1?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with fumonisin b1?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with fumonisin b1

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Per page 10 20 50 100 | Total 1278
Authors Title Published Journal PubMed Link
Broomhead JN et al. Chronic effects of fumonisin B1 in broilers and turkeys fed dietary treatments to market age. 2002 Poult. Sci. pmid:11885900
Ferrante MC et al. Effect of fumonisin B1 on structure and function of macrophage plasma membrane. 2002 Toxicol. Lett. pmid:11888701
Harvey B et al. Toxicity of fumonisin from Fusarium verticillioides culture material and moniliformin from Fusarium fujikuroi culture material when fed singly and in combination to growing barrows. 2002 J. Food Prot. pmid:11848570
Poling SM et al. N-(1-deoxy-D-fructos-1-yl) fumonisin B(1), the initial reaction product of fumonisin B(1) and D-glucose. 2002 J. Agric. Food Chem. pmid:11853524
Gelderblom WC et al. Interaction of fumonisin B(1) and aflatoxin B(1) in a short-term carcinogenesis model in rat liver. 2002 Toxicology pmid:11836022
Lefrancois S et al. The lysosomal transport of prosaposin requires the conditional interaction of its highly conserved d domain with sphingomyelin. 2002 J. Biol. Chem. pmid:11856752
Brandwagt BF et al. Overexpression of the tomato Asc-1 gene mediates high insensitivity to AAL toxins and fumonisin B1 in tomato hairy roots and confers resistance to Alternaria alternata f. sp. lycopersici in Nicotiana umbratica plants. 2002 Mol. Plant Microbe Interact. pmid:11858172
Itakura A et al. Ceramide and sphingosine rapidly induce apoptosis of murine mast cells supported by interleukin-3 and stem cell factor. 2002 Exp. Hematol. pmid:11882365
Theumer MG et al. Immunobiological effects of fumonisin B1 in experimental subchronic mycotoxicoses in rats. 2002 Clin. Diagn. Lab. Immunol. pmid:11777845
Mahfoud R et al. pH-dependent interaction of fumonisin B1 with cholesterol: physicochemical and molecular modeling studies at the air-water interface. 2002 J. Agric. Food Chem. pmid:11782202
Wispriyono B et al. A role for the de novo sphingolipids in apoptosis of photosensitized cells. 2002 Exp. Cell Res. pmid:12213223
Chalfant CE et al. De novo ceramide regulates the alternative splicing of caspase 9 and Bcl-x in A549 lung adenocarcinoma cells. Dependence on protein phosphatase-1. 2002 J. Biol. Chem. pmid:11801602
Howard PC et al. Comparison of the toxicity of several fumonisin derivatives in a 28-day feeding study with female B6C3F(1) mice. 2002 Toxicol. Appl. Pharmacol. pmid:12498732
Trucksess MW et al. Occurrence of aflatoxins and fumonisins in Incaparina from Guatemala. 2002 Food Addit Contam pmid:12113662
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Jenkins GM et al. Acute activation of de novo sphingolipid biosynthesis upon heat shock causes an accumulation of ceramide and subsequent dephosphorylation of SR proteins. 2002 J. Biol. Chem. pmid:12200446
Lu Y et al. Characterization of fumonisin B(1)-glucose reaction kinetics and products. 2002 J. Agric. Food Chem. pmid:12137505
Myburg RB et al. Cytotoxicity of fumonisin B1, diethylnitrosamine, and catechol on the SNO esophageal cancer cell line. 2002 Environ. Health Perspect. pmid:12153764
Caloni F et al. Evaluation of Fumonisin B(1) and its metabolites absorption and toxicity on intestinal cells line Caco-2. 2002 Toxicon pmid:12165322
Galvano F et al. DNA damage in astrocytes exposed to fumonisin B1. 2002 Neurochem. Res. pmid:11958538
Banczerowski-Pelyhe I et al. In vivo and in vitro electrophysiological monitoring of rat neocortical activity after dietary fumonisin exposure. 2002 Mycopathologia pmid:11998878
Ehrlich V et al. Fumonisin B(1) is genotoxic in human derived hepatoma (HepG2) cells. 2002 Mutagenesis pmid:11971998
Enongene EN et al. Persistence and reversibility of the elevation in free sphingoid bases induced by fumonisin inhibition of ceramide synthase. 2002 Toxicol. Sci. pmid:12011476
Smith GW et al. Cardiovascular changes associated with intravenous administration of fumonisin B1 in horses. 2002 Am. J. Vet. Res. pmid:11939316
Seefelder W et al. Analysis of fumonisin B(1) in Fusarium proliferatum-infected asparagus spears and garlic bulbs from Germany by liquid chromatography-electrospray ionization mass spectrometry. 2002 J. Agric. Food Chem. pmid:11982398
Venkataraman K et al. Upstream of growth and differentiation factor 1 (uog1), a mammalian homolog of the yeast longevity assurance gene 1 (LAG1), regulates N-stearoyl-sphinganine (C18-(dihydro)ceramide) synthesis in a fumonisin B1-independent manner in mammalian cells. 2002 J. Biol. Chem. pmid:12105227
Kim EK et al. Extraction of fumonisins B1 and B2 from white rice flour and their stability in white rice flour, cornstarch, cornmeal, and glucose. 2002 J. Agric. Food Chem. pmid:12033838
Akao Y et al. Ceramide accumulation is independent of camptothecin-induced apoptosis in prostate cancer LNCaP cells. 2002 Biochem. Biophys. Res. Commun. pmid:12051721
Fotso J et al. Production of beauvericin, moniliformin, fusaproliferin, and fumonisins b(1), b(2), and b(3) by fifteen ex-type strains of fusarium species. 2002 Appl. Environ. Microbiol. pmid:12324376
Dresden-Osborne C and Noblet GP Fumonisin B1 affects viability and alters nitric oxide production of a murine macrophage cell line. 2002 Int. Immunopharmacol. pmid:12349946
Sadler TW et al. Prevention of fumonisin B1-induced neural tube defects by folic acid. 2002 Teratology pmid:12353213
Bhandari N et al. Fumonisin B1-induced localized activation of cytokine network in mouse liver. 2002 Food Chem. Toxicol. pmid:12387313
Desjardins AE et al. FUM1--a gene required for fumonisin biosynthesis but not for maize ear rot and ear infection by Gibberella moniliformis in field tests. 2002 Mol. Plant Microbe Interact. pmid:12423021
Cortez-Rocha MO et al. Effect of extrusion processing on fumonisin B(1) and hydrolyzed fumonisin B(1) in contaminated alkali-cooked corn. 2002 Bull Environ Contam Toxicol pmid:12232716
Le Stunff H et al. Sphingosine-1-phosphate phosphohydrolase in regulation of sphingolipid metabolism and apoptosis. 2002 J. Cell Biol. pmid:12235122
Camargos SM et al. Accumulation of fumonisins B1 and B2 in freshly harvested Brazilian commercial maize at three locations during two nonconsecutive seasons. 2002 Mycopathologia pmid:12650599
Kong JY and Rabkin SW Palmitate-induced cardiac apoptosis is mediated through CPT-1 but not influenced by glucose and insulin. 2002 Am. J. Physiol. Heart Circ. Physiol. pmid:11788422
Min JK et al. Simultaneous quantitative analysis of sphingoid base 1-phosphates in biological samples by o-phthalaldehyde precolumn derivatization after dephosphorylation with alkaline phosphatase. 2002 Anal. Biochem. pmid:11950216
Baron CL and Malhotra V Role of diacylglycerol in PKD recruitment to the TGN and protein transport to the plasma membrane. 2002 Science pmid:11729268
Galvano F et al. DNA damage in human fibroblasts exposed to fumonisin B(1). 2002 Food Chem. Toxicol. pmid:11731033
Bakan B et al. Fungal growth and fusarium mycotoxin content in isogenic traditional maize and genetically modified maize grown in France and Spain. 2002 J. Agric. Food Chem. pmid:11829636
Bird CB et al. Determination of total fumonisins in corn by competitive direct enzyme-linked immunosorbent assay: collaborative study. 2002 Mar-Apr J AOAC Int pmid:11990026
Blomqvist M et al. Selective lack of the C16:0 fatty acid isoform of sulfatide in pancreas of type II diabetic animal models. 2003 APMIS pmid:14510644
Avantaggiato G et al. Effects of muffin processing on fumonisins from 14C-labeled toxins produced in cultured corn kernels. 2003 J. Food Prot. pmid:14572226
Sharma RP et al. Increased expression of CD95-ligand and other apoptotic signaling factors by fumonisin B1, a hepatotoxic mycotoxin, in livers of mice lacking tumor necrosis factor alpha. 2003 Cytokine pmid:14596819
Zhao H et al. Anoxia and reoxygenation of human endothelial cells decrease ceramide glucosyltransferase expression and activates caspases. 2003 FASEB J. pmid:12586734
Leung LW et al. Inhibitors of glycosphingolipid biosynthesis reduce transepithelial electrical resistance in MDCK I and FRT cells. 2003 Am. J. Physiol., Cell Physiol. pmid:12490435
Ho JA and Durst RA Detection of fumonisin B1: comparison of flow-injection liposome immunoanalysis with high-performance liquid chromatography. 2003 Anal. Biochem. pmid:12479829
Mobio TA et al. Comparative study of the toxic effects of fumonisin B1 in rat C6 glioma cells and p53-null mouse embryo fibroblasts. 2003 Toxicology pmid:12504343
Seefelder W et al. Bound fumonisin B1: analysis of fumonisin-B1 glyco and amino acid conjugates by liquid chromatography-electrospray ionization-tandem mass spectrometry. 2003 J. Agric. Food Chem. pmid:12926916