fumonisin b1

fumonisin b1 is a lipid of Sphingolipids (SP) class. Fumonisin b1 is associated with abnormalities such as Infection, Kidney Diseases, Liver diseases, DERMATITIS HERPETIFORMIS, FAMILIAL and Malnutrition. The involved functions are known as Gene Expression, Anabolism, Signal, Biosynthetic Pathways and Regulation. Fumonisin b1 often locates in Body tissue, Microsomes, microsomal membrane, Protoplasm and Mitochondria. The associated genes with fumonisin b1 are Genome, P4HTM gene, FATE1 gene, BCL2 gene and TMEM132D gene. The related lipids are dihydroceramide, ceramide 1-phosphate, Sphingolipids, Fatty Acids and Palmitates.

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Introduction

To understand associated biological information of fumonisin b1, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with fumonisin b1?

fumonisin b1 is suspected in Infection, Kidney Diseases, Liver diseases, DERMATITIS HERPETIFORMIS, FAMILIAL, Malnutrition, Celiac Disease and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with fumonisin b1

MeSH term MeSH ID Detail
Neuroectodermal Tumors, Primitive, Peripheral D018241 3 associated lipids
Adenoma, Liver Cell D018248 2 associated lipids
Pneumonia, Bacterial D018410 16 associated lipids
Chemical and Drug Induced Liver Injury D056486 39 associated lipids
Per page 10 20 50 100 | Total 54

PubChem Associated disorders and diseases

What pathways are associated with fumonisin b1

Lipid pathways are not clear in current pathway databases. We organized associated pathways with fumonisin b1 through full-text articles, including metabolic pathways or pathways of biological mechanisms.

Related references are published most in these journals:

Pathway name Related literatures
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PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with fumonisin b1?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with fumonisin b1?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with fumonisin b1?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with fumonisin b1?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with fumonisin b1?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with fumonisin b1

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Per page 10 20 50 100 | Total 1278
Authors Title Published Journal PubMed Link
Blackwell BA et al. Oxidative deamination of hydrolyzed fumonisin B(1) (AP(1)) by cultures of Exophiala spinifera. 1999 Nat. Toxins pmid:10441035
Wild CP et al. Absence of a synergistic effect between fumonisin B1 and N-nitrosomethylbenzylamine in the induction of oesophageal papillomas in the rat. 1997 Nat. Toxins pmid:9285918
Ritieni A et al. Isolation and characterization of fusaproliferin, a new toxic metabolite from Fusarium proliferatum. 1995 Nat. Toxins pmid:7749578
Rotter BA et al. Response of growing swine to dietary exposure to pure fumonisin B1 during an eight-week period: growth and clinical parameters. 1996 Nat. Toxins pmid:8680753
Prelusky DB et al. Pharmacokinetic fate of 14C-labelled fumonisin B1 in swine. 1994 Nat. Toxins pmid:8075896
Vudathala DK et al. Pharmacokinetic fate and pathological effects of 14C-fumonisin B1 in laying hens. 1994 Nat. Toxins pmid:8075897
Riley RT et al. Alteration in sphingolipid metabolism: bioassays for fumonisin- and ISP-I-like activity in tissues, cells and other matrices. 1999 Nat. Toxins pmid:11122537
Bucci TJ et al. Leukoencephalomalacia and hemorrhage in the brain of rabbits gavaged with mycotoxin fumonisin B1. 1996 Nat. Toxins pmid:8680754
Toxicology and carcinogenesis studies of fumonisin B1 (cas no. 116355-83-0) in F344/N rats and B6C3F1 mice (feed studies). 2001 Natl Toxicol Program Tech Rep Ser pmid:11852482
Galvano F et al. DNA damage in astrocytes exposed to fumonisin B1. 2002 Neurochem. Res. pmid:11958538
Callihan P et al. Distinct generation, pharmacology, and distribution of sphingosine 1-phosphate and dihydrosphingosine 1-phosphate in human neural progenitor cells. 2012 Neuropharmacology pmid:22016110
Plo I et al. Involvement of de novo ceramide biosynthesis in lymphotoxin-induced oligodendrocyte death. 1999 Neuroreport pmid:10439466
Yang MS et al. Sphingomyelinase but not ceramide induces nitric oxide synthase expression in rat brain microglia. 2001 Neurosci. Lett. pmid:11567796
Domijan AM et al. Impact of fumonisin B1 on glutamate toxicity and low magnesium-induced seizure activity in neuronal primary culture. 2012 Neuroscience pmid:22178271
Kwon OS et al. Biochemical and morphological effects of fumonisin B(1) on primary cultures of rat cerebrum. 2000 Jul-Aug Neurotoxicol Teratol pmid:10974595
Kwon OS et al. Effects of fumonisin B1 treatment on blood-brain barrier transfer in developing rats. 1997 Mar-Apr Neurotoxicol Teratol pmid:9136132
Poersch AB et al. Fumonisin B1 facilitates seizures induced by pentylenetetrazol in mice. Neurotoxicol Teratol pmid:26342287
Osuchowski MF and Sharma RP Fumonisin B1 induces necrotic cell death in BV-2 cells and murine cultured astrocytes and is antiproliferative in BV-2 cells while N2A cells and primary cortical neurons are resistant. 2005 Neurotoxicology pmid:16005069
Ferguson SA et al. Prenatal fumonisin (FB1) treatment in rats results in minimal maternal or offspring toxicity. 1997 Neurotoxicology pmid:9291504
Monnet-Tschudi F et al. The naturally occurring food mycotoxin fumonisin B1 impairs myelin formation in aggregating brain cell culture. 1999 Neurotoxicology pmid:10091857