fumonisin b1

fumonisin b1 is a lipid of Sphingolipids (SP) class. Fumonisin b1 is associated with abnormalities such as Infection, Kidney Diseases, Liver diseases, DERMATITIS HERPETIFORMIS, FAMILIAL and Malnutrition. The involved functions are known as Gene Expression, Anabolism, Signal, Biosynthetic Pathways and Regulation. Fumonisin b1 often locates in Body tissue, Microsomes, microsomal membrane, Protoplasm and Mitochondria. The associated genes with fumonisin b1 are Genome, P4HTM gene, FATE1 gene, BCL2 gene and TMEM132D gene. The related lipids are dihydroceramide, ceramide 1-phosphate, Sphingolipids, Fatty Acids and Palmitates.

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Introduction

To understand associated biological information of fumonisin b1, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with fumonisin b1?

fumonisin b1 is suspected in Infection, Kidney Diseases, Liver diseases, DERMATITIS HERPETIFORMIS, FAMILIAL, Malnutrition, Celiac Disease and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with fumonisin b1

MeSH term MeSH ID Detail
Adenoma, Liver Cell D018248 2 associated lipids
Scrapie D012608 7 associated lipids
Neuroectodermal Tumors, Primitive, Peripheral D018241 3 associated lipids
Pseudorabies D011557 1 associated lipids
Per page 10 20 50 100 | Total 54

PubChem Associated disorders and diseases

What pathways are associated with fumonisin b1

Lipid pathways are not clear in current pathway databases. We organized associated pathways with fumonisin b1 through full-text articles, including metabolic pathways or pathways of biological mechanisms.

Related references are published most in these journals:

Pathway name Related literatures
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PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with fumonisin b1?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with fumonisin b1?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with fumonisin b1?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with fumonisin b1?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with fumonisin b1?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with fumonisin b1

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Per page 10 20 50 100 | Total 1278
Authors Title Published Journal PubMed Link
Trigo-Stockli DM et al. Fumonisin B1 levels in 1995 and 1996 Kansas corn. 2002 Bull Environ Contam Toxicol pmid:12068939
Pósa R et al. Interaction of Bordetella bronchiseptica, Pasteurella multocida, and fumonisin B1 in the porcine respiratory tract as studied by computed tomography. 2011 Can. J. Vet. Res. pmid:22210993
Park MA et al. Vorinostat and sorafenib increase ER stress, autophagy and apoptosis via ceramide-dependent CD95 and PERK activation. 2008 Cancer Biol. Ther. pmid:18787411
Abnet CC et al. Sphingolipids as biomarkers of fumonisin exposure and risk of esophageal squamous cell carcinoma in china. 2001 Cancer Causes Control pmid:11714110
Voss KA et al. Carcinogenicity and mechanism of action of fumonisin B1: a mycotoxin produced by Fusarium moniliforme (= F. verticillioides). 2002 Cancer Detect. Prev. pmid:12088196
van der Westhuizen L et al. Fumonisin B1 as a urinary biomarker of exposure in a maize intervention study among South African subsistence farmers. 2011 Cancer Epidemiol. Biomarkers Prev. pmid:21266524
Gong YY et al. Association between tortilla consumption and human urinary fumonisin B1 levels in a Mexican population. 2008 Cancer Epidemiol. Biomarkers Prev. pmid:18349288
Gelderblom WC et al. Cancer initiation by fumonisin B(1) in rat liver--role of cell proliferation. 2001 Cancer Lett. pmid:11431101
Gelderblom WC et al. The cancer-promoting potential of fumonisin B1 in rat liver using diethylnitrosamine as a cancer initiator. 1996 Cancer Lett. pmid:9020908
Sahu SC et al. Peroxidation of membrane lipids and oxidative DNA damage by fumonisin B1 in isolated rat liver nuclei. 1998 Cancer Lett. pmid:9566705
Lemmer ER et al. The effects of dietary iron overload on fumonisin B1-induced cancer promotion in the rat liver. 1999 Cancer Lett. pmid:10656628
Takasaki M et al. Cancer chemopreventive activity of euglobal-G1 from leaves of Eucalyptus grandis. 2000 Cancer Lett. pmid:10814880
Mehta R et al. Glutathione S-transferase-placental form expression and proliferation of hepatocytes in fumonisin B1-treated male and female Sprague-Dawley rats. 1998 Cancer Lett. pmid:9652790
Blázquez C et al. Cannabinoids inhibit the vascular endothelial growth factor pathway in gliomas. 2004 Cancer Res. pmid:15313899
Wang XZ et al. Aberrant sphingolipid signaling is involved in the resistance of prostate cancer cell lines to chemotherapy. 1999 Cancer Res. pmid:10582708
Huang C et al. Repression of protein kinase C and stimulation of cyclic AMP response elements by fumonisin, a fungal encoded toxin which is a carcinogen. 1995 Cancer Res. pmid:7712470
Garzotto M et al. 12-O-tetradecanoylphorbol-13-acetate-induced apoptosis in LNCaP cells is mediated through ceramide synthase. 1998 Cancer Res. pmid:9605775
Blázquez C et al. Cannabinoids inhibit glioma cell invasion by down-regulating matrix metalloproteinase-2 expression. 2008 Cancer Res. pmid:18339876
Lemmer ER et al. Histopathology and gene expression changes in rat liver during feeding of fumonisin B1, a carcinogenic mycotoxin produced by Fusarium moniliforme. 1999 Carcinogenesis pmid:10334199
Pinelli E et al. Activation of mitogen-activated protein kinase by fumonisin B(1) stimulates cPLA(2) phosphorylation, the arachidonic acid cascade and cAMP production. 1999 Carcinogenesis pmid:10469611