fumonisin b1

fumonisin b1 is a lipid of Sphingolipids (SP) class. Fumonisin b1 is associated with abnormalities such as Infection, Kidney Diseases, Liver diseases, DERMATITIS HERPETIFORMIS, FAMILIAL and Malnutrition. The involved functions are known as Gene Expression, Anabolism, Signal, Biosynthetic Pathways and Regulation. Fumonisin b1 often locates in Body tissue, Microsomes, microsomal membrane, Protoplasm and Mitochondria. The associated genes with fumonisin b1 are Genome, P4HTM gene, FATE1 gene, BCL2 gene and TMEM132D gene. The related lipids are dihydroceramide, ceramide 1-phosphate, Sphingolipids, Fatty Acids and Palmitates.

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Introduction

To understand associated biological information of fumonisin b1, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with fumonisin b1?

fumonisin b1 is suspected in Infection, Kidney Diseases, Liver diseases, DERMATITIS HERPETIFORMIS, FAMILIAL, Malnutrition, Celiac Disease and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with fumonisin b1

MeSH term MeSH ID Detail
Mycoses D009181 18 associated lipids
Carcinoma D002277 18 associated lipids
Esophageal Neoplasms D004938 20 associated lipids
Poultry Diseases D011201 21 associated lipids
Pulmonary Edema D011654 23 associated lipids
Cardiovascular Diseases D002318 24 associated lipids
Glioblastoma D005909 27 associated lipids
Brain Diseases D001927 27 associated lipids
Kidney Diseases D007674 29 associated lipids
Kidney Neoplasms D007680 29 associated lipids
Per page 10 20 50 100 | Total 54

PubChem Associated disorders and diseases

What pathways are associated with fumonisin b1

Lipid pathways are not clear in current pathway databases. We organized associated pathways with fumonisin b1 through full-text articles, including metabolic pathways or pathways of biological mechanisms.

Related references are published most in these journals:

Pathway name Related literatures
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PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with fumonisin b1?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with fumonisin b1?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with fumonisin b1?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with fumonisin b1?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with fumonisin b1?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with fumonisin b1

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Per page 10 20 50 100 | Total 1278
Authors Title Published Journal PubMed Link
El Bawab S et al. Biochemical characterization of the reverse activity of rat brain ceramidase. A CoA-independent and fumonisin B1-insensitive ceramide synthase. 2001 J. Biol. Chem. pmid:11278489
Chalfant CE et al. FAS activation induces dephosphorylation of SR proteins; dependence on the de novo generation of ceramide and activation of protein phosphatase 1. 2001 J. Biol. Chem. pmid:11502750
Riley RT et al. Sphingolipid perturbations as mechanisms for fumonisin carcinogenesis. 2001 Environ. Health Perspect. pmid:11359699
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He Q et al. Fumonisin-induced tumor necrosis factor-alpha expression in a porcine kidney cell line is independent of sphingoid base accumulation induced by ceramide synthase inhibition. 2001 Toxicol. Appl. Pharmacol. pmid:11437650
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Soeda S et al. Daunorubicin attenuates tumor necrosis factor-alpha-induced biosynthesis of plasminogen activator inhibitor-1 in human umbilical vein endothelial cells. 2001 Biochim. Biophys. Acta pmid:11336794
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Kroesen BJ et al. Induction of apoptosis through B-cell receptor cross-linking occurs via de novo generated C16-ceramide and involves mitochondria. 2001 J. Biol. Chem. pmid:11278517
Shim WB and Woloshuk CP Regulation of fumonisin B(1) biosynthesis and conidiation in Fusarium verticillioides by a cyclin-like (C-type) gene, FCC1. 2001 Appl. Environ. Microbiol. pmid:11282612
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Miguet C et al. Ceramide generation occurring during 7beta-hydroxycholesterol- and 7-ketocholesterol-induced apoptosis is caspase independent and is not required to trigger cell death. 2001 Cell Death Differ. pmid:11313706
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Proceedings of the International Conference on the Toxicology of Fumonisin. 28-30 June 1999, Arlington, Virginia. 2001 Environ. Health Perspect. pmid:11359690
Marasas WF Discovery and occurrence of the fumonisins: a historical perspective. 2001 Environ. Health Perspect. pmid:11359691
ApSimon JW Structure, synthesis, and biosynthesis of fumonisin B1 and related compounds. 2001 Environ. Health Perspect. pmid:11359692
Haschek WM et al. Fumonisin toxicosis in swine: an overview of porcine pulmonary edema and current perspectives. 2001 Environ. Health Perspect. pmid:11359693
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Gelderblom WC et al. Toxicity of culture material of Fusarium verticillioides strain MRC 826 to nonhuman primates. 2001 Environ. Health Perspect. pmid:11359695
Howard PC et al. Fumonisin b1 carcinogenicity in a two-year feeding study using F344 rats and B6C3F1 mice. 2001 Environ. Health Perspect. pmid:11359696
Merrill AH et al. Sphingolipid metabolism: roles in signal transduction and disruption by fumonisins. 2001 Environ. Health Perspect. pmid:11359697
Gelderblom WC et al. Fumonisin-induced hepatocarcinogenesis: mechanisms related to cancer initiation and promotion. 2001 Environ. Health Perspect. pmid:11359698
Howard PC et al. Compensatory regeneration as a mechanism for renal tubule carcinogenesis of fumonisin B1 in the F344/N/Nctr BR rat. 2001 Environ. Health Perspect. pmid:11359700
Jones C et al. Analysis of fumonisin B1-induced apoptosis. 2001 Environ. Health Perspect. pmid:11359701
Miller JD Factors that affect the occurrence of fumonisin. 2001 Environ. Health Perspect. pmid:11359702
Bezombes C et al. Lysosomal sphingomyelinase is not solicited for apoptosis signaling. 2001 FASEB J. pmid:11156942
Carlson DB et al. Fumonisin B1 promotes aflatoxin B1 and N-methyl-N'-nitro-nitrosoguanidine-initiated liver tumors in rainbow trout. 2001 Toxicol. Appl. Pharmacol. pmid:11264020
Zhang Y et al. Identification of differentially expressed genes following treatment of monkey kidney cells with the mycotoxin fumonisin B(1). 2001 Food Chem. Toxicol. pmid:11259850
Maragos CM et al. Fluorescence polarization as a means for determination of fumonisins in maize. 2001 J. Agric. Food Chem. pmid:11261998
Momany FA and Dombrink-Kurtzman MA Molecular dynamics simulations on the mycotoxin fumonisin B1. 2001 J. Agric. Food Chem. pmid:11262071
Schmidt K et al. Regulated apical secretion of zymogens in rat pancreas. Involvement of the glycosylphosphatidylinositol-anchored glycoprotein GP-2, the lectin ZG16p, and cholesterol-glycosphingolipid-enriched microdomains. 2001 J. Biol. Chem. pmid:11152672
Ziulkoski AL et al. De novo synthesis and recycling pathways of sphingomyelin in rat Sertoli cells. 2001 Biochem. Biophys. Res. Commun. pmid:11237757
Gumprecht LA et al. Species and organ specificity of fumonisin-induced endothelial alterations: potential role in porcine pulmonary edema. 2001 Toxicology pmid:11246126
van der Westhuizen L et al. The effect of repeated gavage doses of fumonisin B1 on the sphinganine and sphingosine levels in vervet monkeys. 2001 Toxicon pmid:11223085
Mathur S et al. Fumonisin B(1) increases serum sphinganine concentration but does not alter serum sphingosine concentration or induce cardiovascular changes in milk-fed calves. 2001 Toxicol. Sci. pmid:11248151
Mathur S et al. Fumonisin B(1) is hepatotoxic and nephrotoxic in milk-fed calves. 2001 Toxicol. Sci. pmid:11248152
Sewram V et al. Assessing chronic exposure to fumonisin mycotoxins: the use of hair as a suitable noninvasive matrix. 2001 J Anal Toxicol pmid:11550819
Torres AM et al. Fusarium species (section Liseola) and its mycotoxins in maize harvested in northern Argentina. 2001 Food Addit Contam pmid:11552751
Chourasia HK Efficacy of ammonia in detoxification of fumonisin contaminated corn. 2001 Indian J. Exp. Biol. pmid:11510139
Martins ML et al. Fumonisins B1 and B2 in black tea and medicinal plants. 2001 J. Food Prot. pmid:11510675
Ono EY et al. Evaluation of fumonisin-aflatoxin co-occurrence in Brazilian corn hybrids by ELISA. 2001 Food Addit Contam pmid:11469328
Omurtag GZ Determination of fumonisin B1 and B2 in corn and corn-based products in Turkey by high-performance liquid chromatography. 2001 J. Food Prot. pmid:11456195
Spotti M et al. Fumonisin B1 metabolism by bovine liver microsomes. 2001 Vet. Res. Commun. pmid:11519682
Yu CH et al. Differential effects of fumonisin B1 on cell death in cultured cells: the significance of the elevated sphinganine. 2001 Arch. Pharm. Res. pmid:11339633
Dilkin P et al. Robotic automated clean-up for detection of fumonisins B1 and B2 in corn and corn-based feed by high-performance liquid chromatography. 2001 J Chromatogr A pmid:11519801