fumonisin b1

fumonisin b1 is a lipid of Sphingolipids (SP) class. Fumonisin b1 is associated with abnormalities such as Infection, Kidney Diseases, Liver diseases, DERMATITIS HERPETIFORMIS, FAMILIAL and Malnutrition. The involved functions are known as Gene Expression, Anabolism, Signal, Biosynthetic Pathways and Regulation. Fumonisin b1 often locates in Body tissue, Microsomes, microsomal membrane, Protoplasm and Mitochondria. The associated genes with fumonisin b1 are Genome, P4HTM gene, FATE1 gene, BCL2 gene and TMEM132D gene. The related lipids are dihydroceramide, ceramide 1-phosphate, Sphingolipids, Fatty Acids and Palmitates.

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Introduction

To understand associated biological information of fumonisin b1, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with fumonisin b1?

fumonisin b1 is suspected in Infection, Kidney Diseases, Liver diseases, DERMATITIS HERPETIFORMIS, FAMILIAL, Malnutrition, Celiac Disease and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with fumonisin b1

MeSH term MeSH ID Detail
Neuronal Ceroid-Lipofuscinoses D009472 5 associated lipids
Neuroblastoma D009447 66 associated lipids
Neural Tube Defects D009436 5 associated lipids
Nervous System Diseases D009422 37 associated lipids
Mycoses D009181 18 associated lipids
Magnesium Deficiency D008275 9 associated lipids
Lung Neoplasms D008175 171 associated lipids
Lung Diseases D008171 37 associated lipids
Liver Neoplasms, Experimental D008114 46 associated lipids
Liver Cirrhosis, Experimental D008106 36 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with fumonisin b1

Lipid pathways are not clear in current pathway databases. We organized associated pathways with fumonisin b1 through full-text articles, including metabolic pathways or pathways of biological mechanisms.

Related references are published most in these journals:

Pathway name Related literatures
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PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with fumonisin b1?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with fumonisin b1?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with fumonisin b1?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with fumonisin b1?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with fumonisin b1?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with fumonisin b1

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Per page 10 20 50 100 | Total 1278
Authors Title Published Journal PubMed Link
El Bawab S et al. Biochemical characterization of the reverse activity of rat brain ceramidase. A CoA-independent and fumonisin B1-insensitive ceramide synthase. 2001 J. Biol. Chem. pmid:11278489
Chalfant CE et al. FAS activation induces dephosphorylation of SR proteins; dependence on the de novo generation of ceramide and activation of protein phosphatase 1. 2001 J. Biol. Chem. pmid:11502750
Lemke SL et al. Deamination of fumonisin B(1) and biological assessment of reaction product toxicity. 2001 Chem. Res. Toxicol. pmid:11170503
Toxicology and carcinogenesis studies of fumonisin B1 (cas no. 116355-83-0) in F344/N rats and B6C3F1 mice (feed studies). 2001 Natl Toxicol Program Tech Rep Ser pmid:11852482
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Kroesen BJ et al. Induction of apoptosis through B-cell receptor cross-linking occurs via de novo generated C16-ceramide and involves mitochondria. 2001 J. Biol. Chem. pmid:11278517
Shim WB and Woloshuk CP Regulation of fumonisin B(1) biosynthesis and conidiation in Fusarium verticillioides by a cyclin-like (C-type) gene, FCC1. 2001 Appl. Environ. Microbiol. pmid:11282612
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Proceedings of the International Conference on the Toxicology of Fumonisin. 28-30 June 1999, Arlington, Virginia. 2001 Environ. Health Perspect. pmid:11359690
Marasas WF Discovery and occurrence of the fumonisins: a historical perspective. 2001 Environ. Health Perspect. pmid:11359691
ApSimon JW Structure, synthesis, and biosynthesis of fumonisin B1 and related compounds. 2001 Environ. Health Perspect. pmid:11359692
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Voss KA et al. An overview of rodent toxicities: liver and kidney effects of fumonisins and Fusarium moniliforme. 2001 Environ. Health Perspect. pmid:11359694
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Howard PC et al. Fumonisin b1 carcinogenicity in a two-year feeding study using F344 rats and B6C3F1 mice. 2001 Environ. Health Perspect. pmid:11359696
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Gelderblom WC et al. Fumonisin-induced hepatocarcinogenesis: mechanisms related to cancer initiation and promotion. 2001 Environ. Health Perspect. pmid:11359698
Howard PC et al. Compensatory regeneration as a mechanism for renal tubule carcinogenesis of fumonisin B1 in the F344/N/Nctr BR rat. 2001 Environ. Health Perspect. pmid:11359700
Jones C et al. Analysis of fumonisin B1-induced apoptosis. 2001 Environ. Health Perspect. pmid:11359701
Miller JD Factors that affect the occurrence of fumonisin. 2001 Environ. Health Perspect. pmid:11359702
Bacon CW et al. Biological control of Fusarium moniliforme in maize. 2001 Environ. Health Perspect. pmid:11359703
Saunders DS et al. Control of fumonisin: effects of processing. 2001 Environ. Health Perspect. pmid:11359704
Duvick J Prospects for reducing fumonisin contamination of maize through genetic modification. 2001 Environ. Health Perspect. pmid:11359705
Nagy B et al. FADD null mouse embryonic fibroblasts undergo apoptosis after photosensitization with the silicon phthalocyanine Pc 4. 2001 Arch. Biochem. Biophys. pmid:11361017
Hartl M and Humpf HU Combined synthetic/CD strategy for the stereochemical assignment of the tricarballylic acid side chains of fumonisin B(1). 2001 J. Org. Chem. pmid:11374984
Bezombes C et al. Lysosomal sphingomyelinase is not solicited for apoptosis signaling. 2001 FASEB J. pmid:11156942
Eppley RM Preparatory isolation of mycotoxins from solid phase fungal cultures. 2001 Methods Mol. Biol. pmid:11050990
Wilkes JG and Lay JO Electrospray mass spectrometry for mycotoxin detection and purity analysis. 2001 Methods Mol. Biol. pmid:11050992
Shephard GS Liquid chromatographic method for fumonisins in corn. 2001 Methods Mol. Biol. pmid:11051000
Carlson DB et al. Fumonisin B1 promotes aflatoxin B1 and N-methyl-N'-nitro-nitrosoguanidine-initiated liver tumors in rainbow trout. 2001 Toxicol. Appl. Pharmacol. pmid:11264020
Zhang Y et al. Identification of differentially expressed genes following treatment of monkey kidney cells with the mycotoxin fumonisin B(1). 2001 Food Chem. Toxicol. pmid:11259850
Maragos CM et al. Fluorescence polarization as a means for determination of fumonisins in maize. 2001 J. Agric. Food Chem. pmid:11261998
Momany FA and Dombrink-Kurtzman MA Molecular dynamics simulations on the mycotoxin fumonisin B1. 2001 J. Agric. Food Chem. pmid:11262071
Schmidt K et al. Regulated apical secretion of zymogens in rat pancreas. Involvement of the glycosylphosphatidylinositol-anchored glycoprotein GP-2, the lectin ZG16p, and cholesterol-glycosphingolipid-enriched microdomains. 2001 J. Biol. Chem. pmid:11152672
Ziulkoski AL et al. De novo synthesis and recycling pathways of sphingomyelin in rat Sertoli cells. 2001 Biochem. Biophys. Res. Commun. pmid:11237757
Gumprecht LA et al. Species and organ specificity of fumonisin-induced endothelial alterations: potential role in porcine pulmonary edema. 2001 Toxicology pmid:11246126
van der Westhuizen L et al. The effect of repeated gavage doses of fumonisin B1 on the sphinganine and sphingosine levels in vervet monkeys. 2001 Toxicon pmid:11223085
Sharma RP et al. Decreased fumonisin hepatotoxicity in mice with a targeted deletion of tumor necrosis factor receptor 1. 2001 Toxicology pmid:11250056
Ueda N et al. Role of ceramide synthase in oxidant injury to renal tubular epithelial cells. 2001 J. Am. Soc. Nephrol. pmid:11675414
Mathur S et al. Fumonisin B(1) increases serum sphinganine concentration but does not alter serum sphingosine concentration or induce cardiovascular changes in milk-fed calves. 2001 Toxicol. Sci. pmid:11248151
Mathur S et al. Fumonisin B(1) is hepatotoxic and nephrotoxic in milk-fed calves. 2001 Toxicol. Sci. pmid:11248152
Martins ML et al. Fumonisins B1 and B2 in black tea and medicinal plants. 2001 J. Food Prot. pmid:11510675
Ono EY et al. Evaluation of fumonisin-aflatoxin co-occurrence in Brazilian corn hybrids by ELISA. 2001 Food Addit Contam pmid:11469328
Omurtag GZ Determination of fumonisin B1 and B2 in corn and corn-based products in Turkey by high-performance liquid chromatography. 2001 J. Food Prot. pmid:11456195
Spotti M et al. Fumonisin B1 metabolism by bovine liver microsomes. 2001 Vet. Res. Commun. pmid:11519682
Yu CH et al. Differential effects of fumonisin B1 on cell death in cultured cells: the significance of the elevated sphinganine. 2001 Arch. Pharm. Res. pmid:11339633
Dilkin P et al. Robotic automated clean-up for detection of fumonisins B1 and B2 in corn and corn-based feed by high-performance liquid chromatography. 2001 J Chromatogr A pmid:11519801