fumonisin b1

fumonisin b1 is a lipid of Sphingolipids (SP) class. Fumonisin b1 is associated with abnormalities such as Infection, Kidney Diseases, Liver diseases, DERMATITIS HERPETIFORMIS, FAMILIAL and Malnutrition. The involved functions are known as Gene Expression, Anabolism, Signal, Biosynthetic Pathways and Regulation. Fumonisin b1 often locates in Body tissue, Microsomes, microsomal membrane, Protoplasm and Mitochondria. The associated genes with fumonisin b1 are Genome, P4HTM gene, FATE1 gene, BCL2 gene and TMEM132D gene. The related lipids are dihydroceramide, ceramide 1-phosphate, Sphingolipids, Fatty Acids and Palmitates.

Cross Reference

Introduction

To understand associated biological information of fumonisin b1, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with fumonisin b1?

fumonisin b1 is suspected in Infection, Kidney Diseases, Liver diseases, DERMATITIS HERPETIFORMIS, FAMILIAL, Malnutrition, Celiac Disease and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
Loading... please refresh the page if content is not showing up.

Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with fumonisin b1

MeSH term MeSH ID Detail
Spinal Cord Injuries D013119 34 associated lipids
Hyperplasia D006965 34 associated lipids
Liver Cirrhosis, Experimental D008106 36 associated lipids
Lung Diseases D008171 37 associated lipids
Nervous System Diseases D009422 37 associated lipids
Chemical and Drug Induced Liver Injury D056486 39 associated lipids
Adenoma D000236 40 associated lipids
Liver Neoplasms, Experimental D008114 46 associated lipids
Fatty Liver D005234 48 associated lipids
Precancerous Conditions D011230 48 associated lipids
Per page 10 20 50 100 | Total 54

PubChem Associated disorders and diseases

What pathways are associated with fumonisin b1

Lipid pathways are not clear in current pathway databases. We organized associated pathways with fumonisin b1 through full-text articles, including metabolic pathways or pathways of biological mechanisms.

Related references are published most in these journals:

Pathway name Related literatures
Loading... please refresh the page if content is not showing up.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with fumonisin b1?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
Loading... please refresh the page if content is not showing up.

What functions are associated with fumonisin b1?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with fumonisin b1?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
Loading... please refresh the page if content is not showing up.

What genes are associated with fumonisin b1?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with fumonisin b1?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with fumonisin b1

Download all related citations
Per page 10 20 50 100 | Total 1278
Authors Title Published Journal PubMed Link
Frisvad JC et al. Fumonisin B2 production by Aspergillus niger. 2007 J. Agric. Food Chem. pmid:17929891
Rumora L et al. Mycotoxin fumonisin B1 alters cellular redox balance and signalling pathways in rat liver and kidney. 2007 Toxicology pmid:17949882
Karuna R and Sashidhar RB The mycotoxin fumonisin B1 inhibits eukaryotic protein synthesis: in vitro and in vivo studies. 2008 Mycopathologia pmid:17968675
Yi F et al. Mechanism of homocysteine-induced Rac1/NADPH oxidase activation in mesangial cells: role of guanine nucleotide exchange factor Vav2. 2007 Cell. Physiol. Biochem. pmid:17982273
Deshmukh S et al. Pathologic changes in extrahepatic organs and agglutinin response to Salmonella Gallinarum infection in Japanese quail fed Fusarium verticillioides culture material containing known levels of fumonisin B1. 2007 Avian Dis. pmid:17992930
Dambolena JS et al. Inhibitory effect of cyclic terpenes (limonene, menthol, menthone and thymol) on Fusarium verticillioides MRC 826 growth and fumonisin B1 biosynthesis. 2008 Toxicon pmid:18037463
Masini E et al. Ceramide: a key signaling molecule in a Guinea pig model of allergic asthmatic response and airway inflammation. 2008 J. Pharmacol. Exp. Ther. pmid:18042827
Shi L et al. Involvement of sphingoid bases in mediating reactive oxygen intermediate production and programmed cell death in Arabidopsis. 2007 Cell Res. pmid:18059378
Gbore FA and Egbunike GN Testicular and epididymal sperm reserves and sperm production of pubertal boars fed dietary fumonisin B(1). 2008 Anim. Reprod. Sci. pmid:18155863
Gnonlonfin GJ et al. Mycoflora and natural occurrence of aflatoxins and fumonisin B1 in cassava and yam chips from Benin, West Africa. 2008 Int. J. Food Microbiol. pmid:18160162
Choi YE and Shim WB Functional characterization of Fusarium verticillioides CPP1, a gene encoding a putative protein phosphatase 2A catalytic subunit. 2008 Microbiology (Reading, Engl.) pmid:18174151
Stockmann-Juvala H et al. Effects of fumonisin B(1) on the expression of cytokines and chemokines in human dendritic cells. 2008 Food Chem. Toxicol. pmid:18194833
Yang LX et al. [Association between murine double minute 2 expression and AngII and ceramide induced endothelial cells apoptosis]. 2007 Zhonghua Xin Xue Guan Bing Za Zhi pmid:18206046
Liu YY et al. A role for ceramide in driving cancer cell resistance to doxorubicin. 2008 FASEB J. pmid:18245173
Theumer MG et al. The lipid-mediated hypothesis of fumonisin B1 toxicodynamics tested in model membranes. 2008 Colloids Surf B Biointerfaces pmid:18296035
Roscoe V et al. Mycotoxins in breakfast cereals from the Canadian retail market: a 3-year survey. 2008 Food Addit Contam Part A Chem Anal Control Expo Risk Assess pmid:18311625
Bullerman LB et al. Reduction of fumonisin B1 in corn grits by single-screw extrusion. 2008 J. Agric. Food Chem. pmid:18327966
Blázquez C et al. Cannabinoids inhibit glioma cell invasion by down-regulating matrix metalloproteinase-2 expression. 2008 Cancer Res. pmid:18339876
Gong YY et al. Association between tortilla consumption and human urinary fumonisin B1 levels in a Mexican population. 2008 Cancer Epidemiol. Biomarkers Prev. pmid:18349288
Korfmacher WA et al. Characterization of the mycotoxin fumonisin B1: comparison of thermospray, fast-atom bombardment and electrospray mass spectrometry. 1991 Rapid Commun. Mass Spectrom. pmid:1841646
Kim H and Woloshuk CP Role of AREA, a regulator of nitrogen metabolism, during colonization of maize kernels and fumonisin biosynthesis in Fusarium verticillioides. 2008 Fungal Genet. Biol. pmid:18440841
Odhav B et al. Modulating effects of fumonisin B1 and ochratoxin A on leukocytes and messenger cytokines of the human immune system. 2008 Int. Immunopharmacol. pmid:18442783
Marina Martins H et al. Fumonisins and deoxynivalenol in corn-based food products in Portugal. 2008 Food Chem. Toxicol. pmid:18486293
Sharma D et al. Individual and combined effects of fumonisin b1 and moniliformin on clinicopathological and cell-mediated immune response in Japanese quail. 2008 Poult. Sci. pmid:18492990
Boudra H and Morgavi DP Reduction in fusarium toxin levels in corn silage with low dry matter and storage time. 2008 J. Agric. Food Chem. pmid:18498169
Kim JE et al. AMPK activator, AICAR, inhibits palmitate-induced apoptosis in osteoblast. 2008 Bone pmid:18502715
Senyuva HZ et al. Determination of fumonisins B1 and B2 in corn by liquid chromatography/mass spectrometry with immunoaffinity column cleanup: single-laboratory method validation. 2008 May-Jun J AOAC Int pmid:18567306
Tardieu D et al. Determination of Fumonisin B1 in animal tissues with immunoaffinity purification. 2008 J. Chromatogr. B Analyt. Technol. Biomed. Life Sci. pmid:18571484
Yano T [Etiology of iodinated radiocontrast nephrotoxicity and its attenuation by beraprost]. 2008 Yakugaku Zasshi pmid:18591870
Wang E et al. Inhibition of sphingolipid biosynthesis by fumonisins. Implications for diseases associated with Fusarium moniliforme. 1991 J. Biol. Chem. pmid:1860857
Cuzzocrea S et al. Anti-inflammatory and anti-apoptotic effects of fumonisin B1, an inhibitor of ceramide synthase, in a rodent model of splanchnic ischemia and reperfusion injury. 2008 J. Pharmacol. Exp. Ther. pmid:18612046
Gelderblom WC et al. Cancer initiating properties of fumonisin B1 in a short-term rat liver carcinogenesis assay. 2008 Toxicology pmid:18616970
Luongo D et al. Effects of four Fusarium toxins (fumonisin B(1), alpha-zearalenol, nivalenol and deoxynivalenol) on porcine whole-blood cellular proliferation. 2008 Toxicon pmid:18620720
Kim B et al. Cytotoxicity of fumonisin B(1) in spheroid and monolayer cultures of rat hepatocytes. 2008 Drug Chem Toxicol pmid:18622869
Nieto FL et al. Sphingolipid metabolism is a crucial determinant of cellular fate in nonstimulated proliferating Madin-Darby canine kidney (MDCK) cells. 2008 J. Biol. Chem. pmid:18625703
Gong HZ et al. Occurrence of fumonisin B(1) in corn from the main corn-producing areas of China. 2009 Mycopathologia pmid:18636342
Lin SS et al. RING1 E3 ligase localizes to plasma membrane lipid rafts to trigger FB1-induced programmed cell death in Arabidopsis. 2008 Plant J. pmid:18643987
Cuzzocrea S et al. Fumonisin b1 reduces the development of multiple organ failure induced by zymosan in mice. 2009 Shock pmid:18650782
Maysinger D et al. Ceramide is responsible for the failure of compensatory nerve sprouting in apolipoprotein E knock-out mice. 2008 J. Neurosci. pmid:18667621
Muscarella M et al. Development of a new analytical method for the determination of fumonisins B1 and B2 in food products based on high performance liquid chromatography and fluorimetric detection with post-column derivatization. 2008 J Chromatogr A pmid:18674770
Severino L et al. Immune effects of four Fusarium-toxins (FB1, ZEA, NIV, DON) on the proliferation of Jurkat cells and porcine lymphocytes: in vitro study. 2008 Vet. Res. Commun. pmid:18683067
Tardieu D et al. Toxicokinetics of fumonisin B1 in turkey poults and tissue persistence after exposure to a diet containing the maximum European tolerance for fumonisins in avian feeds. 2008 Food Chem. Toxicol. pmid:18700162
Park MA et al. Vorinostat and sorafenib increase ER stress, autophagy and apoptosis via ceramide-dependent CD95 and PERK activation. 2008 Cancer Biol. Ther. pmid:18787411
Nogueira TC et al. Involvement of phosphatidylinositol-3 kinase/AKT/PKCzeta/lambda pathway in the effect of palmitate on glucose-induced insulin secretion. 2008 Pancreas pmid:18815554
Cuzzocrea S et al. Inhibition of ceramide biosynthesis ameliorates pathological consequences of spinal cord injury. 2009 Shock pmid:18838947
Ross PF et al. Concentrations of fumonisin B1 in feeds associated with animal health problems. 1991 Mycopathologia pmid:1886638
Voss KA et al. Reduced toxicity of fumonisin B1 in corn grits by single-screw extrusion. 2008 J. Food Prot. pmid:18939749
Izquierdo-Useros N et al. Capture and transfer of HIV-1 particles by mature dendritic cells converges with the exosome-dissemination pathway. 2009 Blood pmid:18945959
Eichele K et al. R(+)-methanandamide-induced apoptosis of human cervical carcinoma cells involves a cyclooxygenase-2-dependent pathway. 2009 Pharm. Res. pmid:19015962
Hu LB et al. Inhibition of fengycins on the production of fumonisin B1 from Fusarium verticillioides. 2009 Lett. Appl. Microbiol. pmid:19018959