| MeSH term | MeSH ID | Detail |
|---|---|---|
| Leukemia, Myeloid | D007951 | 52 associated lipids |
| Kidney Neoplasms | D007680 | 29 associated lipids |
| Kidney Diseases | D007674 | 29 associated lipids |
| Inflammation | D007249 | 119 associated lipids |
| Hyperplasia | D006965 | 34 associated lipids |
| Hydrocephalus | D006849 | 6 associated lipids |
| Carcinoma, Hepatocellular | D006528 | 140 associated lipids |
| Glioma | D005910 | 112 associated lipids |
| Glioblastoma | D005909 | 27 associated lipids |
| Gaucher Disease | D005776 | 13 associated lipids |
fumonisin b1
fumonisin b1 is a lipid of Sphingolipids (SP) class. Fumonisin b1 is associated with abnormalities such as Infection, Kidney Diseases, Liver diseases, DERMATITIS HERPETIFORMIS, FAMILIAL and Malnutrition. The involved functions are known as Gene Expression, Anabolism, Signal, Biosynthetic Pathways and Regulation. Fumonisin b1 often locates in Body tissue, Microsomes, microsomal membrane, Protoplasm and Mitochondria. The associated genes with fumonisin b1 are Genome, P4HTM gene, FATE1 gene, BCL2 gene and TMEM132D gene. The related lipids are dihydroceramide, ceramide 1-phosphate, Sphingolipids, Fatty Acids and Palmitates.
Cross Reference
Introduction
To understand associated biological information of fumonisin b1, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with fumonisin b1?
fumonisin b1 is suspected in Infection, Kidney Diseases, Liver diseases, DERMATITIS HERPETIFORMIS, FAMILIAL, Malnutrition, Celiac Disease and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
- Am. J. Physiol. Heart Circ. Physiol. (1)
- Am. J. Physiol. Regul. Integr. Comp. Physiol. (1)
- Cancer Res. (1)
- Others (5)
| Disease | Cross reference | Weighted score | Related literature |
|---|
Loading... please refresh the page if content is not showing up.
Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with fumonisin b1
PubChem Associated disorders and diseases
What pathways are associated with fumonisin b1
Lipid pathways are not clear in current pathway databases. We organized associated pathways with fumonisin b1 through full-text articles, including metabolic pathways or pathways of biological mechanisms.
Related references are published most in these journals:
| Pathway name | Related literatures |
|---|
Loading... please refresh the page if content is not showing up.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with fumonisin b1?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
Loading... please refresh the page if content is not showing up.
What functions are associated with fumonisin b1?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with fumonisin b1?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
|---|
Loading... please refresh the page if content is not showing up.
What genes are associated with fumonisin b1?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with fumonisin b1?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with fumonisin b1
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Gopee NV et al. | Fumonisin B1-induced apoptosis is associated with delayed inhibition of protein kinase C, nuclear factor-kappaB and tumor necrosis factor alpha in LLC-PK1 cells. | 2003 | Chem. Biol. Interact. | pmid:14597127 |
| Bhandari N et al. | Modulation of selected cell signaling genes in mouse liver by fumonisin B1. | 2002 | Chem. Biol. Interact. | pmid:11879819 |
| Tran ST et al. | Sphinganine to sphingosine ratio and predictive biochemical markers of fumonisin B1 exposure in ducks. | 2003 | Chem. Biol. Interact. | pmid:12902153 |
| Tardieu D et al. | Tissue persistence of fumonisin B1 in ducks and after exposure to a diet containing the maximum European tolerance for fumonisins in avian feeds. | 2009 | Chem. Biol. Interact. | pmid:19559689 |
| Orsi RB et al. | Acute toxicity of a single gavage dose of fumonisin B1 in rabbits. | 2009 | Chem. Biol. Interact. | pmid:19330885 |
| Johnson VJ et al. | Increased susceptibility of renal epithelial cells to TNFalpha-induced apoptosis following treatment with fumonisin B1. | 2003 | Chem. Biol. Interact. | pmid:12732456 |
| Sharma N et al. | Sphingosine kinase activity confers resistance to apoptosis by fumonisin B1 in human embryonic kidney (HEK-293) cells. | 2004 | Chem. Biol. Interact. | pmid:15607760 |
| Tardieu D et al. | Effects of fumonisins on liver and kidney sphinganine and the sphinganine to sphingosine ratio during chronic exposure in ducks. | 2006 | Chem. Biol. Interact. | pmid:16412405 |
| Tran ST et al. | Serum sphinganine and the sphinganine to sphingosine ratio as a biomarker of dietary fumonisins during chronic exposure in ducks. | 2006 | Chem. Biol. Interact. | pmid:16413517 |
| Inooka S and Toyokuni T | Use of fumonisin B1 to test the intercellular transfer of sphingosine. | 1996 | Cell. Signal. | pmid:8958448 |
| Yi F et al. | Mechanism of homocysteine-induced Rac1/NADPH oxidase activation in mesangial cells: role of guanine nucleotide exchange factor Vav2. | 2007 | Cell. Physiol. Biochem. | pmid:17982273 |
| Schilling T and Eder C | Importance of lipid rafts for lysophosphatidylcholine-induced caspase-1 activation and reactive oxygen species generation. | 2010 | Cell. Immunol. | pmid:20832779 |
| Shi L et al. | Involvement of sphingoid bases in mediating reactive oxygen intermediate production and programmed cell death in Arabidopsis. | 2007 | Cell Res. | pmid:18059378 |
| Aflaki E et al. | C16 ceramide is crucial for triacylglycerol-induced apoptosis in macrophages. | 2012 | Cell Death Dis | pmid:22419109 |
| Lang KS et al. | Involvement of ceramide in hyperosmotic shock-induced death of erythrocytes. | 2004 | Cell Death Differ. | pmid:14615798 |
| Appierto V et al. | Involvement of c-Fos in fenretinide-induced apoptosis in human ovarian carcinoma cells. | 2004 | Cell Death Differ. | pmid:14647238 |
| Miguet C et al. | Ceramide generation occurring during 7beta-hydroxycholesterol- and 7-ketocholesterol-induced apoptosis is caspase independent and is not required to trigger cell death. | 2001 | Cell Death Differ. | pmid:11313706 |
| Ciarlo L et al. | Association of fission proteins with mitochondrial raft-like domains. | 2010 | Cell Death Differ. | pmid:20075943 |
| Gamen S et al. | Caspases are the main executioners of Fas-mediated apoptosis, irrespective of the ceramide signalling pathway. | 1998 | Cell Death Differ. | pmid:10200470 |
| Spinedi A et al. | Ceramide accumulation precedes caspase-dependent apoptosis in CHP-100 neuroepithelioma cells exposed to the protein phosphatase inhibitor okadaic acid. | 1999 | Cell Death Differ. | pmid:10453072 |
| Gopee NV and Sharma RP | The mycotoxin fumonisin B1 transiently activates nuclear factor-kappaB, tumor necrosis factor alpha and caspase 3 via protein kinase Calpha-dependent pathway in porcine renal epithelial cells. | 2004 | Cell Biol. Toxicol. | pmid:15499968 |
| Gelderblom WC et al. | Toxicity and carcinogenicity of the Fusarium moniliforme metabolite, fumonisin B1, in rats. | 1991 | Carcinogenesis | pmid:1649015 |
| Gelderblom WC et al. | The cancer-initiating potential of the fumonisin B mycotoxins. | 1992 | Carcinogenesis | pmid:1547534 |
| Lemmer ER et al. | Fumonisin B1-induced hepatocellular and cholangiocellular tumors in male Fischer 344 rats: potentiating effects of 2-acetylaminofluorene on oval cell proliferation and neoplastic development in a discontinued feeding study. | 2004 | Carcinogenesis | pmid:14988222 |
| Lemmer ER et al. | Histopathology and gene expression changes in rat liver during feeding of fumonisin B1, a carcinogenic mycotoxin produced by Fusarium moniliforme. | 1999 | Carcinogenesis | pmid:10334199 |
| Gelderblom WC et al. | Fumonisin B1 dosimetry in relation to cancer initiation in rat liver. | 1994 | Carcinogenesis | pmid:8313510 |
| Pinelli E et al. | Activation of mitogen-activated protein kinase by fumonisin B(1) stimulates cPLA(2) phosphorylation, the arachidonic acid cascade and cAMP production. | 1999 | Carcinogenesis | pmid:10469611 |
| Tolleson WH et al. | Apoptotic and anti-proliferative effects of fumonisin B1 in human keratinocytes, fibroblasts, esophageal epithelial cells and hepatoma cells. | 1996 | Carcinogenesis | pmid:8625445 |
| Abdel Nour AM et al. | Folate receptor and human reduced folate carrier expression in HepG2 cell line exposed to fumonisin B1 and folate deficiency. | 2007 | Carcinogenesis | pmid:17615259 |
| Ramljak D et al. | A potential mechanism for fumonisin B(1)-mediated hepatocarcinogenesis: cyclin D1 stabilization associated with activation of Akt and inhibition of GSK-3beta activity. | 2000 | Carcinogenesis | pmid:10910956 |
| Blázquez C et al. | Cannabinoids inhibit the vascular endothelial growth factor pathway in gliomas. | 2004 | Cancer Res. | pmid:15313899 |
| Wang XZ et al. | Aberrant sphingolipid signaling is involved in the resistance of prostate cancer cell lines to chemotherapy. | 1999 | Cancer Res. | pmid:10582708 |
| Huang C et al. | Repression of protein kinase C and stimulation of cyclic AMP response elements by fumonisin, a fungal encoded toxin which is a carcinogen. | 1995 | Cancer Res. | pmid:7712470 |
| Garzotto M et al. | 12-O-tetradecanoylphorbol-13-acetate-induced apoptosis in LNCaP cells is mediated through ceramide synthase. | 1998 | Cancer Res. | pmid:9605775 |
| Blázquez C et al. | Cannabinoids inhibit glioma cell invasion by down-regulating matrix metalloproteinase-2 expression. | 2008 | Cancer Res. | pmid:18339876 |
| Gelderblom WC et al. | Cancer initiation by fumonisin B(1) in rat liver--role of cell proliferation. | 2001 | Cancer Lett. | pmid:11431101 |
| Gelderblom WC et al. | The cancer-promoting potential of fumonisin B1 in rat liver using diethylnitrosamine as a cancer initiator. | 1996 | Cancer Lett. | pmid:9020908 |
| Sahu SC et al. | Peroxidation of membrane lipids and oxidative DNA damage by fumonisin B1 in isolated rat liver nuclei. | 1998 | Cancer Lett. | pmid:9566705 |
| Lemmer ER et al. | The effects of dietary iron overload on fumonisin B1-induced cancer promotion in the rat liver. | 1999 | Cancer Lett. | pmid:10656628 |
| Takasaki M et al. | Cancer chemopreventive activity of euglobal-G1 from leaves of Eucalyptus grandis. | 2000 | Cancer Lett. | pmid:10814880 |
| Mehta R et al. | Glutathione S-transferase-placental form expression and proliferation of hepatocytes in fumonisin B1-treated male and female Sprague-Dawley rats. | 1998 | Cancer Lett. | pmid:9652790 |
| van der Westhuizen L et al. | Fumonisin B1 as a urinary biomarker of exposure in a maize intervention study among South African subsistence farmers. | 2011 | Cancer Epidemiol. Biomarkers Prev. | pmid:21266524 |
| Gong YY et al. | Association between tortilla consumption and human urinary fumonisin B1 levels in a Mexican population. | 2008 | Cancer Epidemiol. Biomarkers Prev. | pmid:18349288 |
| Voss KA et al. | Carcinogenicity and mechanism of action of fumonisin B1: a mycotoxin produced by Fusarium moniliforme (= F. verticillioides). | 2002 | Cancer Detect. Prev. | pmid:12088196 |
| Abnet CC et al. | Sphingolipids as biomarkers of fumonisin exposure and risk of esophageal squamous cell carcinoma in china. | 2001 | Cancer Causes Control | pmid:11714110 |
| Park MA et al. | Vorinostat and sorafenib increase ER stress, autophagy and apoptosis via ceramide-dependent CD95 and PERK activation. | 2008 | Cancer Biol. Ther. | pmid:18787411 |
| Pósa R et al. | Interaction of Bordetella bronchiseptica, Pasteurella multocida, and fumonisin B1 in the porcine respiratory tract as studied by computed tomography. | 2011 | Can. J. Vet. Res. | pmid:22210993 |
| Cortez-Rocha MO et al. | Effect of extrusion processing on fumonisin B(1) and hydrolyzed fumonisin B(1) in contaminated alkali-cooked corn. | 2002 | Bull Environ Contam Toxicol | pmid:12232716 |
| Beier RC et al. | Calculated three dimensional structures of the fumonisin B1-4 mycotoxins. | 1995 | Bull Environ Contam Toxicol | pmid:7767023 |
| Cortez-Rocha MO et al. | Occurrence of fumonisin B1 and hydrolyzed fumonisin B1 in Mexican nixtamalized cornmeal. | 2005 | Bull Environ Contam Toxicol | pmid:15768501 |