| MeSH term | MeSH ID | Detail |
|---|---|---|
| Asthma | D001249 | 52 associated lipids |
| Leukemia, Myeloid | D007951 | 52 associated lipids |
| Neuroblastoma | D009447 | 66 associated lipids |
| Stomach Ulcer | D013276 | 75 associated lipids |
| Seizures | D012640 | 87 associated lipids |
| Weight Gain | D015430 | 101 associated lipids |
| Glioma | D005910 | 112 associated lipids |
| Inflammation | D007249 | 119 associated lipids |
| Prostatic Neoplasms | D011471 | 126 associated lipids |
| Cell Transformation, Neoplastic | D002471 | 126 associated lipids |
fumonisin b1
fumonisin b1 is a lipid of Sphingolipids (SP) class. Fumonisin b1 is associated with abnormalities such as Infection, Kidney Diseases, Liver diseases, DERMATITIS HERPETIFORMIS, FAMILIAL and Malnutrition. The involved functions are known as Gene Expression, Anabolism, Signal, Biosynthetic Pathways and Regulation. Fumonisin b1 often locates in Body tissue, Microsomes, microsomal membrane, Protoplasm and Mitochondria. The associated genes with fumonisin b1 are Genome, P4HTM gene, FATE1 gene, BCL2 gene and TMEM132D gene. The related lipids are dihydroceramide, ceramide 1-phosphate, Sphingolipids, Fatty Acids and Palmitates.
Cross Reference
Introduction
To understand associated biological information of fumonisin b1, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with fumonisin b1?
fumonisin b1 is suspected in Infection, Kidney Diseases, Liver diseases, DERMATITIS HERPETIFORMIS, FAMILIAL, Malnutrition, Celiac Disease and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
Loading... please refresh the page if content is not showing up.
Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with fumonisin b1
PubChem Associated disorders and diseases
What pathways are associated with fumonisin b1
Lipid pathways are not clear in current pathway databases. We organized associated pathways with fumonisin b1 through full-text articles, including metabolic pathways or pathways of biological mechanisms.
Related references are published most in these journals:
| Pathway name | Related literatures |
|---|
Loading... please refresh the page if content is not showing up.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with fumonisin b1?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
Loading... please refresh the page if content is not showing up.
What functions are associated with fumonisin b1?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with fumonisin b1?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
|---|
Loading... please refresh the page if content is not showing up.
What genes are associated with fumonisin b1?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with fumonisin b1?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with fumonisin b1
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Rentz SS et al. | Inhibition of sphingolipid biosynthesis decreases phosphorylated ERK2 in LLC-PK1 cells. | 2005 | Food Chem. Toxicol. | pmid:15582204 |
| Flynn TJ et al. | Assessment of the embryotoxic potential of the total hydrolysis product of fumonisin B1 using cultured organogenesis-staged rat embryos. | 1997 | Food Chem. Toxicol. | pmid:9449218 |
| Riedel S et al. | Induction of an altered lipid phenotype by two cancer promoting treatments in rat liver. | 2015 | Food Chem. Toxicol. | pmid:25656646 |
| Magoha H et al. | Fumonisin B1 contamination in breast milk and its exposure in infants under 6 months of age in Rombo, Northern Tanzania. | 2014 | Food Chem. Toxicol. | pmid:25280923 |
| Sheu CW et al. | Lack of transforming activity of fumonisin B1 in BALB/3T3 A31-1-1 mouse embryo cells. | 1996 | Food Chem. Toxicol. | pmid:8883477 |
| Szabó A et al. | Individual and combined haematotoxic effects of fumonisin B(1) and T-2 mycotoxins in rabbits. | 2014 | Food Chem. Toxicol. | pmid:25092395 |
| Casado JM et al. | Experimental subchronic mycotoxicoses in mice: individual and combined effects of dietary exposure to fumonisins and aflatoxin B1. | 2001 | Food Chem. Toxicol. | pmid:11346488 |
| Bouhet S et al. | Mycotoxin fumonisin B1 selectively down-regulates the basal IL-8 expression in pig intestine: in vivo and in vitro studies. | 2006 | Food Chem. Toxicol. | pmid:16843581 |
| Gelderblom WC et al. | Effect of fumonisin B1 on the levels and fatty acid composition of selected lipids in rat liver in vivo. | 1997 | Food Chem. Toxicol. | pmid:9301647 |
| Marina Martins H et al. | Fumonisins and deoxynivalenol in corn-based food products in Portugal. | 2008 | Food Chem. Toxicol. | pmid:18486293 |
| van der Westhuizen L et al. | Sphinganine/sphingosine ratio in plasma and urine as a possible biomarker for fumonisin exposure in humans in rural areas of Africa. | 1999 | Food Chem. Toxicol. | pmid:10654591 |
| Aly SE et al. | Application of adsorbent agents technology in the removal of aflatoxin B(1) and fumonisin B(1) from malt extract. | 2004 | Food Chem. Toxicol. | pmid:15350680 |
| Norred WP et al. | Effectiveness of ammonia treatment in detoxification of fumonisin-contaminated corn. | 1991 | Food Chem. Toxicol. | pmid:1765326 |
| Collins TF et al. | Effects of fumonisin B1 in pregnant rats. | 1998 | Food Chem. Toxicol. | pmid:9662415 |
| Norred WP et al. | Effects of selected secondary metabolites of Fusarium moniliforme on unscheduled synthesis of DNA by rat primary hepatocytes. | 1992 | Food Chem. Toxicol. | pmid:1618447 |
| Shephard GS et al. | Initial studies on the toxicokinetics of fumonisin B1 in rats. | 1992 | Food Chem. Toxicol. | pmid:1628862 |
| Karbancioglu-Güler F and Heperkan D | Natural occurrence of fumonisin B1 in dried figs as an unexpected hazard. | 2009 | Food Chem. Toxicol. | pmid:19032973 |
| Marnewick JL et al. | Chemoprotective properties of rooibos (Aspalathus linearis), honeybush (Cyclopia intermedia) herbal and green and black (Camellia sinensis) teas against cancer promotion induced by fumonisin B1 in rat liver. | 2009 | Food Chem. Toxicol. | pmid:19041360 |
| Bhandari N et al. | Fumonisin B1-induced localized activation of cytokine network in mouse liver. | 2002 | Food Chem. Toxicol. | pmid:12387313 |
| Cetin Y and Bullerman LB | Cytotoxicity of Fusarium mycotoxins to mammalian cell cultures as determined by the MTT bioassay. | 2005 | Food Chem. Toxicol. | pmid:15778016 |
| Meca G et al. | Isolation, purification, LC-MS/MS characterization and reactive oxygen species induced by fumonisin B1 in VERO cells. | 2010 | Food Chem. Toxicol. | pmid:20655973 |
| Denli M et al. | Efficacy of AdiDetoxâ„¢ in reducing the toxicity of fumonisin B1 in rats. | 2015 | Food Chem. Toxicol. | pmid:25660482 |
| Hahn I et al. | Effects of orally administered fumonisin Bâ‚ (FBâ‚), partially hydrolysed FBâ‚, hydrolysed FBâ‚ and N-(1-deoxy-D-fructos-1-yl) FBâ‚ on the sphingolipid metabolism in rats. | 2015 | Food Chem. Toxicol. | pmid:25475052 |
| Shephard GS et al. | Determination of the mycotoxin fumonisin B1 and identification of its partially hydrolysed metabolites in the faeces of non-human primates. | 1994 | Food Chem. Toxicol. | pmid:8132161 |
| Müller S et al. | Fumonisin B1 and the kidney: modes of action for renal tumor formation by fumonisin B1 in rodents. | 2012 | Food Chem. Toxicol. | pmid:22771819 |
| Collins TF et al. | Effects of fumonisin B1 in pregnant rats. Part 2. | 1998 | Food Chem. Toxicol. | pmid:9734718 |
| Chamberlain WJ et al. | Levels of fumonisin B1 in corn naturally contaminated with aflatoxins. | 1993 | Food Chem. Toxicol. | pmid:8282284 |
| Wan LY et al. | Individual and combined cytotoxic effects of Fusarium toxins (deoxynivalenol, nivalenol, zearalenone and fumonisins B1) on swine jejunal epithelial cells. | 2013 | Food Chem. Toxicol. | pmid:23562706 |
| Bondy G et al. | Toxicity of fumonisin B1 administered intraperitoneally to male Sprague-Dawley rats. | 1995 | Food Chem. Toxicol. | pmid:7672738 |
| Singh MP and Kang SC | Endoplasmic reticulum stress-mediated autophagy activation attenuates fumonisin B1 induced hepatotoxicity in vitro and in vivo. | 2017 | Food Chem. Toxicol. | pmid:29097114 |
| Souto PCMC et al. | Determination of fumonisin B levels in body fluids and hair from piglets fed fumonisin B-contaminated diets. | 2017 | Food Chem. Toxicol. | pmid:28733235 |
| He Q et al. | Myriocin prevents fumonisin B1-induced sphingoid base accumulation in mice liver without ameliorating hepatotoxicity. | 2005 | Food Chem. Toxicol. | pmid:15811577 |
| Dilkin P et al. | Toxicological effects of chronic low doses of aflatoxin B(1) and fumonisin B(1)-containing Fusarium moniliforme culture material in weaned piglets. | 2003 | Food Chem. Toxicol. | pmid:12909268 |
| Gelderblom WC et al. | Effect of fumonisin B1 on protein and lipid synthesis in primary rat hepatocytes. | 1996 | Food Chem. Toxicol. | pmid:8641662 |
| Hartl M and Humpf HU | Toxicity assessment of fumonisins using the brine shrimp (Artemia salina) bioassay. | 2000 | Food Chem. Toxicol. | pmid:11033198 |
| Ciacci-Zanella JR and Jones C | Fumonisin B1, a mycotoxin contaminant of cereal grains, and inducer of apoptosis via the tumour necrosis factor pathway and caspase activation. | 1999 | Food Chem. Toxicol. | pmid:10496371 |
| Escrivá L et al. | In vivo toxicity studies of fusarium mycotoxins in the last decade: a review. | 2015 | Food Chem. Toxicol. | pmid:25680507 |
| Voss KA et al. | Fusaric acid and modification of the subchronic toxicity to rats of fumonisins in F. moniliforme culture material. | 1999 | Food Chem. Toxicol. | pmid:10506009 |
| Stockmann-Juvala H et al. | Effects of fumonisin B(1) on the expression of cytokines and chemokines in human dendritic cells. | 2008 | Food Chem. Toxicol. | pmid:18194833 |
| Mary VS et al. | Effects of aflatoxin Bâ‚, fumonisin Bâ‚ and their mixture on the aryl hydrocarbon receptor and cytochrome P450 1A induction. | 2015 | Food Chem. Toxicol. | pmid:25449202 |
| van der Westhuizen L et al. | Inhibition of sphingolipid biosynthesis in rat primary hepatocyte cultures by fumonisin B1 and other structurally related compounds. | 1998 | Food Chem. Toxicol. | pmid:9674957 |
| Zhang Y et al. | Identification of differentially expressed genes following treatment of monkey kidney cells with the mycotoxin fumonisin B(1). | 2001 | Food Chem. Toxicol. | pmid:11259850 |
| Lerda D et al. | Fumonisins in foods from Cordoba (Argentina), presence and genotoxicity. | 2005 | Food Chem. Toxicol. | pmid:15778008 |
| Gelderblom WC et al. | Structure-activity relationships of fumonisins in short-term carcinogenesis and cytotoxicity assays. | 1993 | Food Chem. Toxicol. | pmid:8514212 |
| Enongene EN et al. | Disruption of sphingolipid metabolism in small intestines, liver and kidney of mice dosed subcutaneously with fumonisin B(1). | 2000 | Food Chem. Toxicol. | pmid:10930700 |
| Esposito F et al. | Exposure assessment to fumonisins B, B and B through consumption of gluten-free foodstuffs intended for people affected by celiac disease. | 2016 | Food Chem. Toxicol. | pmid:27746327 |
| Cawood ME et al. | Interaction of 14C-labelled fumonisin B mycotoxins with primary rat hepatocyte cultures. | 1994 | Food Chem. Toxicol. | pmid:8045475 |
| Galvano F et al. | DNA damage in human fibroblasts exposed to fumonisin B(1). | 2002 | Food Chem. Toxicol. | pmid:11731033 |
| Norred WP et al. | Instability of N-acetylated fumonisin B1 (FA1) and the impact on inhibition of ceramide synthase in rat liver slices. | 2001 | Food Chem. Toxicol. | pmid:11527566 |
| Qian G et al. | Sequential dietary exposure to aflatoxin B1 and fumonisin B1 in F344 rats increases liver preneoplastic changes indicative of a synergistic interaction. | 2016 | Food Chem. Toxicol. | pmid:27430420 |