fumonisin b1

fumonisin b1 is a lipid of Sphingolipids (SP) class. Fumonisin b1 is associated with abnormalities such as Infection, Kidney Diseases, Liver diseases, DERMATITIS HERPETIFORMIS, FAMILIAL and Malnutrition. The involved functions are known as Gene Expression, Anabolism, Signal, Biosynthetic Pathways and Regulation. Fumonisin b1 often locates in Body tissue, Microsomes, microsomal membrane, Protoplasm and Mitochondria. The associated genes with fumonisin b1 are Genome, P4HTM gene, FATE1 gene, BCL2 gene and TMEM132D gene. The related lipids are dihydroceramide, ceramide 1-phosphate, Sphingolipids, Fatty Acids and Palmitates.

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Introduction

To understand associated biological information of fumonisin b1, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with fumonisin b1?

fumonisin b1 is suspected in Infection, Kidney Diseases, Liver diseases, DERMATITIS HERPETIFORMIS, FAMILIAL, Malnutrition, Celiac Disease and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with fumonisin b1

MeSH term MeSH ID Detail
Fetal Resorption D005327 15 associated lipids
Fatty Liver D005234 48 associated lipids
Esophageal Neoplasms D004938 20 associated lipids
Death, Sudden D003645 12 associated lipids
Cleft Palate D002972 9 associated lipids
Choline Deficiency D002796 16 associated lipids
Cell Transformation, Neoplastic D002471 126 associated lipids
Cardiovascular Diseases D002318 24 associated lipids
Carcinoma D002277 18 associated lipids
Brain Diseases D001927 27 associated lipids
Per page 10 20 50 100 | Total 54

PubChem Associated disorders and diseases

What pathways are associated with fumonisin b1

Lipid pathways are not clear in current pathway databases. We organized associated pathways with fumonisin b1 through full-text articles, including metabolic pathways or pathways of biological mechanisms.

Related references are published most in these journals:

Pathway name Related literatures
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PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with fumonisin b1?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with fumonisin b1?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with fumonisin b1?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with fumonisin b1?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with fumonisin b1?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with fumonisin b1

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Per page 10 20 50 100 | Total 1278
Authors Title Published Journal PubMed Link
Gopee NV et al. Fumonisin B1-induced apoptosis is associated with delayed inhibition of protein kinase C, nuclear factor-kappaB and tumor necrosis factor alpha in LLC-PK1 cells. 2003 Chem. Biol. Interact. pmid:14597127
Bouhet S et al. The mycotoxin fumonisin B1 alters the proliferation and the barrier function of porcine intestinal epithelial cells. 2004 Toxicol. Sci. pmid:14600282
Suomalainen L et al. Sphingosine-1-phosphate in inhibition of male germ cell apoptosis in the human testis. 2003 J. Clin. Endocrinol. Metab. pmid:14602806
Lang KS et al. Involvement of ceramide in hyperosmotic shock-induced death of erythrocytes. 2004 Cell Death Differ. pmid:14615798
Velluti A et al. Inhibitory effect of cinnamon, clove, lemongrass, oregano and palmarose essential oils on growth and fumonisin B1 production by Fusarium proliferatum in maize grain. 2003 Int. J. Food Microbiol. pmid:14623380
Jiménez M et al. Sugars and amino acids as factors affecting the synthesis of fumonisins in liquid cultures by isolates of the Gibberella fujikuroi complex. 2003 Int. J. Food Microbiol. pmid:14623384
Shim WB et al. Comparison of fumonisin B1 biosynthesis in maize germ and degermed kernels by Fusarium verticillioides. 2003 J. Food Prot. pmid:14627291
Minervini F et al. Toxicity and apoptosis induced by the mycotoxins nivalenol, deoxynivalenol and fumonisin B1 in a human erythroleukemia cell line. 2004 Toxicol In Vitro pmid:14630058
Appierto V et al. Involvement of c-Fos in fenretinide-induced apoptosis in human ovarian carcinoma cells. 2004 Cell Death Differ. pmid:14647238
Cirillo T et al. Evaluation of conventional and organic italian foodstuffs for deoxynivalenol and fumonisins B(1) and B(2). 2003 J. Agric. Food Chem. pmid:14690407
Ledoux DR et al. Individual and combined effects of the Fusarium mycotoxins fumonisin B1 and moniliformin in broiler chicks. 2003 Oct-Dec Avian Dis. pmid:14708984
Gopee NV and Sharma RP Selective and transient activation of protein kinase C alpha by fumonisin B1, a ceramide synthase inhibitor mycotoxin, in cultured porcine renal cells. 2004 Life Sci. pmid:14729403
Kim EK et al. Liquid chromatographic determination of fumonisins B1, B2, and B3 in corn silage. 2004 J. Agric. Food Chem. pmid:14733494
Lu FG and Wong CS Radiation-induced apoptosis of oligodendrocytes and its association with increased ceramide and down-regulated protein kinase B/Akt activity. 2004 Int. J. Radiat. Biol. pmid:14761849
Lemmer ER et al. Fumonisin B1-induced hepatocellular and cholangiocellular tumors in male Fischer 344 rats: potentiating effects of 2-acetylaminofluorene on oval cell proliferation and neoplastic development in a discontinued feeding study. 2004 Carcinogenesis pmid:14988222
Naiker S and Odhav B Mycotic keratitis: profile of Fusarium species and their mycotoxins. 2004 Mycoses pmid:14998400
Foreman JH et al. Neurologic abnormalities and cerebrospinal fluid changes in horses administered fumonisin B1 intravenously. 2004 Mar-Apr J. Vet. Intern. Med. pmid:15058775
Ding Y et al. Fum3p, a 2-ketoglutarate-dependent dioxygenase required for C-5 hydroxylation of fumonisins in Fusarium verticillioides. 2004 Appl. Environ. Microbiol. pmid:15066782
Decker L and ffrench-Constant C Lipid rafts and integrin activation regulate oligodendrocyte survival. 2004 J. Neurosci. pmid:15084663
Shephard GS et al. Fate of a single dose of the 14C-labelled mycotoxin, fumonisin B1, in rats. 1992 Toxicon pmid:1509495