fumonisin b1

fumonisin b1 is a lipid of Sphingolipids (SP) class. Fumonisin b1 is associated with abnormalities such as Infection, Kidney Diseases, Liver diseases, DERMATITIS HERPETIFORMIS, FAMILIAL and Malnutrition. The involved functions are known as Gene Expression, Anabolism, Signal, Biosynthetic Pathways and Regulation. Fumonisin b1 often locates in Body tissue, Microsomes, microsomal membrane, Protoplasm and Mitochondria. The associated genes with fumonisin b1 are Genome, P4HTM gene, FATE1 gene, BCL2 gene and TMEM132D gene. The related lipids are dihydroceramide, ceramide 1-phosphate, Sphingolipids, Fatty Acids and Palmitates.

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Introduction

To understand associated biological information of fumonisin b1, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with fumonisin b1?

fumonisin b1 is suspected in Infection, Kidney Diseases, Liver diseases, DERMATITIS HERPETIFORMIS, FAMILIAL, Malnutrition, Celiac Disease and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with fumonisin b1

MeSH term MeSH ID Detail
Fetal Resorption D005327 15 associated lipids
Fatty Liver D005234 48 associated lipids
Esophageal Neoplasms D004938 20 associated lipids
Death, Sudden D003645 12 associated lipids
Cleft Palate D002972 9 associated lipids
Choline Deficiency D002796 16 associated lipids
Cell Transformation, Neoplastic D002471 126 associated lipids
Cardiovascular Diseases D002318 24 associated lipids
Carcinoma D002277 18 associated lipids
Brain Diseases D001927 27 associated lipids
Per page 10 20 50 100 | Total 54

PubChem Associated disorders and diseases

What pathways are associated with fumonisin b1

Lipid pathways are not clear in current pathway databases. We organized associated pathways with fumonisin b1 through full-text articles, including metabolic pathways or pathways of biological mechanisms.

Related references are published most in these journals:

Pathway name Related literatures
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PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with fumonisin b1?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with fumonisin b1?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with fumonisin b1?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with fumonisin b1?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with fumonisin b1?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with fumonisin b1

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Per page 10 20 50 100 | Total 1278
Authors Title Published Journal PubMed Link
Plattner RD HPLC/MS analysis of fusarium mycotoxins, fumonisins and deoxynivalenol. 1999 Nat. Toxins pmid:11122531
Wu W and Vesonder RF Inhibition of gluconeogenesis in cultured chicken embryo hepatocytes by Fusarium metabolites. 1997 Nat. Toxins pmid:9131594
Prelusky DB et al. Pilot study on the plasma pharmacokinetics of fumonisin B1 in cows following a single dose by oral gavage or intravenous administration. 1995 Nat. Toxins pmid:8581325
Gumprecht LA et al. Effects of intravenous fumonisin B1 in rabbits: nephrotoxicity and sphingolipid alterations. 1995 Nat. Toxins pmid:8581326
Voss KA et al. A preliminary investigation on renal and hepatic toxicity in rats fed purified fumonisin B1. 1993 Nat. Toxins pmid:8167938
Norred WP et al. Distribution and excretion of [14C]fumonisin B1 in male Sprague-Dawley rats. 1993 Nat. Toxins pmid:8167955
Picco M et al. Aflatoxin B1 and fumosin B1 in mixed cultures of Aspergillus flavus and Fusarium proliferatum on maize. 1999 Nat. Toxins pmid:11122525
Maragos CM and Thompson VS Fiber-optic immunosensor for mycotoxins. 1999 Nat. Toxins pmid:11122532
Toxicology and carcinogenesis studies of fumonisin B1 (cas no. 116355-83-0) in F344/N rats and B6C3F1 mice (feed studies). 2001 Natl Toxicol Program Tech Rep Ser pmid:11852482
Galvano F et al. DNA damage in astrocytes exposed to fumonisin B1. 2002 Neurochem. Res. pmid:11958538
Callihan P et al. Distinct generation, pharmacology, and distribution of sphingosine 1-phosphate and dihydrosphingosine 1-phosphate in human neural progenitor cells. 2012 Neuropharmacology pmid:22016110
Plo I et al. Involvement of de novo ceramide biosynthesis in lymphotoxin-induced oligodendrocyte death. 1999 Neuroreport pmid:10439466
Yang MS et al. Sphingomyelinase but not ceramide induces nitric oxide synthase expression in rat brain microglia. 2001 Neurosci. Lett. pmid:11567796
Domijan AM et al. Impact of fumonisin B1 on glutamate toxicity and low magnesium-induced seizure activity in neuronal primary culture. 2012 Neuroscience pmid:22178271
Kwon OS et al. Biochemical and morphological effects of fumonisin B(1) on primary cultures of rat cerebrum. 2000 Jul-Aug Neurotoxicol Teratol pmid:10974595
Kwon OS et al. Effects of fumonisin B1 treatment on blood-brain barrier transfer in developing rats. 1997 Mar-Apr Neurotoxicol Teratol pmid:9136132
Poersch AB et al. Fumonisin B1 facilitates seizures induced by pentylenetetrazol in mice. Neurotoxicol Teratol pmid:26342287
Osuchowski MF and Sharma RP Fumonisin B1 induces necrotic cell death in BV-2 cells and murine cultured astrocytes and is antiproliferative in BV-2 cells while N2A cells and primary cortical neurons are resistant. 2005 Neurotoxicology pmid:16005069
Ferguson SA et al. Prenatal fumonisin (FB1) treatment in rats results in minimal maternal or offspring toxicity. 1997 Neurotoxicology pmid:9291504
Monnet-Tschudi F et al. The naturally occurring food mycotoxin fumonisin B1 impairs myelin formation in aggregating brain cell culture. 1999 Neurotoxicology pmid:10091857