| MeSH term | MeSH ID | Detail |
|---|---|---|
| Carcinoma, Hepatocellular | D006528 | 140 associated lipids |
| Adenocarcinoma | D000230 | 166 associated lipids |
| Lung Neoplasms | D008175 | 171 associated lipids |
| Body Weight | D001835 | 333 associated lipids |
fumonisin b1
fumonisin b1 is a lipid of Sphingolipids (SP) class. Fumonisin b1 is associated with abnormalities such as Infection, Kidney Diseases, Liver diseases, DERMATITIS HERPETIFORMIS, FAMILIAL and Malnutrition. The involved functions are known as Gene Expression, Anabolism, Signal, Biosynthetic Pathways and Regulation. Fumonisin b1 often locates in Body tissue, Microsomes, microsomal membrane, Protoplasm and Mitochondria. The associated genes with fumonisin b1 are Genome, P4HTM gene, FATE1 gene, BCL2 gene and TMEM132D gene. The related lipids are dihydroceramide, ceramide 1-phosphate, Sphingolipids, Fatty Acids and Palmitates.
Cross Reference
Introduction
To understand associated biological information of fumonisin b1, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with fumonisin b1?
fumonisin b1 is suspected in Infection, Kidney Diseases, Liver diseases, DERMATITIS HERPETIFORMIS, FAMILIAL, Malnutrition, Celiac Disease and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with fumonisin b1
PubChem Associated disorders and diseases
What pathways are associated with fumonisin b1
Lipid pathways are not clear in current pathway databases. We organized associated pathways with fumonisin b1 through full-text articles, including metabolic pathways or pathways of biological mechanisms.
Related references are published most in these journals:
| Pathway name | Related literatures |
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PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with fumonisin b1?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
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What functions are associated with fumonisin b1?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
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What lipids are associated with fumonisin b1?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
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What genes are associated with fumonisin b1?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with fumonisin b1?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with fumonisin b1
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Voss KA et al. | Reproductive and sphingolipid metabolic effects of fumonisin B(1) and its alkaline hydrolysis product in LM/Bc mice: hydrolyzed fumonisin B(1) did not cause neural tube defects. | 2009 | Toxicol. Sci. | pmid:19783636 |
| Mathur S et al. | Fumonisin B(1) increases serum sphinganine concentration but does not alter serum sphingosine concentration or induce cardiovascular changes in milk-fed calves. | 2001 | Toxicol. Sci. | pmid:11248151 |
| Ferrante MC et al. | Effect of fumonisin B1 on structure and function of macrophage plasma membrane. | 2002 | Toxicol. Lett. | pmid:11888701 |
| Bondy GS et al. | Retrospective evaluation of serum ornithine carbamyltransferase activity as an index of hepatotoxicity in toxicological studies with rats. | 2000 | Toxicol. Lett. | pmid:10713481 |
| Raynal M et al. | Effects of fumonisin B1 present in Fusarium moniliforme culture material on drug metabolising enzyme activities in ducks. | 2001 | Toxicol. Lett. | pmid:11369472 |
| Wan LY et al. | Individual and combined effects of Fusarium toxins on the mRNA expression of pro-inflammatory cytokines in swine jejunal epithelial cells. | 2013 | Toxicol. Lett. | pmid:23688591 |
| Steyn PS | Mycotoxins, general view, chemistry and structure. | 1995 | Toxicol. Lett. | pmid:8597152 |
| Kuiper-Goodman T | Mycotoxins: risk assessment and legislation. | 1995 | Toxicol. Lett. | pmid:8597153 |
| Clarke R et al. | High content analysis: a sensitive tool to detect and quantify the cytotoxic, synergistic and antagonistic effects of chemical contaminants in foods. | 2015 | Toxicol. Lett. | pmid:25623391 |
| Chuturgoon AA et al. | Fumonisin Bâ‚ modulates expression of human cytochrome P450 1b1 in human hepatoma (Hepg2) cells by repressing Mir-27b. | 2014 | Toxicol. Lett. | pmid:24614526 |
| Fernández-Blanco C et al. | An in vitro investigation on the cytotoxic and nuclear receptor transcriptional activity of the mycotoxins fumonisin B1 and beauvericin. | 2016 | Toxicol. Lett. | pmid:27234500 |
| Chuturgoon AA et al. | Fumonisin Bâ‚ inhibits apoptosis in HepG2 cells by inducing Birc-8/ILP-2. | 2015 | Toxicol. Lett. | pmid:25800559 |
| Liu BH et al. | The effects of mycotoxins, fumonisin B1 and aflatoxin B1, on primary swine alveolar macrophages. | 2002 | Toxicol. Appl. Pharmacol. | pmid:12009859 |
| Cai Q et al. | Validation of fumonisin biomarkers in F344 rats. | 2007 | Toxicol. Appl. Pharmacol. | pmid:17904604 |
| Constable PD et al. | Ingestion of fumonisin B1-containing culture material decreases cardiac contractility and mechanical efficiency in swine. | 2000 | Toxicol. Appl. Pharmacol. | pmid:10652243 |
| Suzuki CA et al. | The effects of fumonisin B1 on several markers of nephrotoxicity in rats. | 1995 | Toxicol. Appl. Pharmacol. | pmid:7645015 |
| Schmelz EM et al. | Induction of apoptosis by fumonisin B1 in HT29 cells is mediated by the accumulation of endogenous free sphingoid bases. | 1998 | Toxicol. Appl. Pharmacol. | pmid:9473533 |
| Norred WP et al. | Mycotoxin-induced elevation of free sphingoid bases in precision-cut rat liver slices: specificity of the response and structure-activity relationships. | 1997 | Toxicol. Appl. Pharmacol. | pmid:9356308 |
| Yoo HS et al. | Elevated sphingoid bases and complex sphingolipid depletion as contributing factors in fumonisin-induced cytotoxicity. | 1996 | Toxicol. Appl. Pharmacol. | pmid:8658522 |
| Kim MS et al. | Fumonisin B(1) induces apoptosis in LLC-PK(1) renal epithelial cells via a sphinganine- and calmodulin-dependent pathway. | 2001 | Toxicol. Appl. Pharmacol. | pmid:11601888 |