fumonisin b1

fumonisin b1 is a lipid of Sphingolipids (SP) class. Fumonisin b1 is associated with abnormalities such as Infection, Kidney Diseases, Liver diseases, DERMATITIS HERPETIFORMIS, FAMILIAL and Malnutrition. The involved functions are known as Gene Expression, Anabolism, Signal, Biosynthetic Pathways and Regulation. Fumonisin b1 often locates in Body tissue, Microsomes, microsomal membrane, Protoplasm and Mitochondria. The associated genes with fumonisin b1 are Genome, P4HTM gene, FATE1 gene, BCL2 gene and TMEM132D gene. The related lipids are dihydroceramide, ceramide 1-phosphate, Sphingolipids, Fatty Acids and Palmitates.

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Introduction

To understand associated biological information of fumonisin b1, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with fumonisin b1?

fumonisin b1 is suspected in Infection, Kidney Diseases, Liver diseases, DERMATITIS HERPETIFORMIS, FAMILIAL, Malnutrition, Celiac Disease and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with fumonisin b1

MeSH term MeSH ID Detail
Neuroectodermal Tumors, Primitive, Peripheral D018241 3 associated lipids
Adenoma, Liver Cell D018248 2 associated lipids
Pneumonia, Bacterial D018410 16 associated lipids
Chemical and Drug Induced Liver Injury D056486 39 associated lipids
Per page 10 20 50 100 | Total 54

PubChem Associated disorders and diseases

What pathways are associated with fumonisin b1

Lipid pathways are not clear in current pathway databases. We organized associated pathways with fumonisin b1 through full-text articles, including metabolic pathways or pathways of biological mechanisms.

Related references are published most in these journals:

Pathway name Related literatures
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PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with fumonisin b1?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with fumonisin b1?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with fumonisin b1?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with fumonisin b1?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with fumonisin b1?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with fumonisin b1

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Per page 10 20 50 100 | Total 1278
Authors Title Published Journal PubMed Link
He Q et al. Fumonisin-induced tumor necrosis factor-alpha expression in a porcine kidney cell line is independent of sphingoid base accumulation induced by ceramide synthase inhibition. 2001 Toxicol. Appl. Pharmacol. pmid:11437650
Martinez-Larrañaga MR et al. Induction of cytochrome P4501A1 and P4504A1 activities and peroxisomal proliferation by fumonisin B1. 1996 Toxicol. Appl. Pharmacol. pmid:8917691
Liu BH et al. The effects of mycotoxins, fumonisin B1 and aflatoxin B1, on primary swine alveolar macrophages. 2002 Toxicol. Appl. Pharmacol. pmid:12009859
Cai Q et al. Validation of fumonisin biomarkers in F344 rats. 2007 Toxicol. Appl. Pharmacol. pmid:17904604
Suzuki CA et al. The effects of fumonisin B1 on several markers of nephrotoxicity in rats. 1995 Toxicol. Appl. Pharmacol. pmid:7645015
Schmelz EM et al. Induction of apoptosis by fumonisin B1 in HT29 cells is mediated by the accumulation of endogenous free sphingoid bases. 1998 Toxicol. Appl. Pharmacol. pmid:9473533
Norred WP et al. Mycotoxin-induced elevation of free sphingoid bases in precision-cut rat liver slices: specificity of the response and structure-activity relationships. 1997 Toxicol. Appl. Pharmacol. pmid:9356308
Yoo HS et al. Elevated sphingoid bases and complex sphingolipid depletion as contributing factors in fumonisin-induced cytotoxicity. 1996 Toxicol. Appl. Pharmacol. pmid:8658522
Kim MS et al. Fumonisin B(1) induces apoptosis in LLC-PK(1) renal epithelial cells via a sphinganine- and calmodulin-dependent pathway. 2001 Toxicol. Appl. Pharmacol. pmid:11601888
Hard GC et al. Rat kidney pathology induced by chronic exposure to fumonisin B1 includes rare variants of renal tubule tumor. 2001 May-Jun Toxicol Pathol pmid:11442024
Bucci TJ et al. Renal effects of fumonisin mycotoxins in animals. 1998 Jan-Feb Toxicol Pathol pmid:9502399
Gumprecht LA et al. Development of fumonisin-induced hepatotoxicity and pulmonary edema in orally dosed swine: morphological and biochemical alterations. 1998 Nov-Dec Toxicol Pathol pmid:9864095
Pósa R et al. A comparative pathological finding in pigs exposed to fumonisin B1 and/or Mycoplasma hyopneumoniae. 2016 Toxicol Ind Health pmid:25107460
Luongo D et al. Interactive effects of fumonisin B1 and alpha-zearalenol on proliferation and cytokine expression in Jurkat T cells. 2006 Toxicol In Vitro pmid:16899350
Minervini F et al. Toxic effects induced by mycotoxin fumonisin B1 on equine spermatozoa: assessment of viability, sperm chromatin structure stability, ROS production and motility. 2010 Toxicol In Vitro pmid:20541003
Bernabucci U et al. Aflatoxin B1 and fumonisin B1 affect the oxidative status of bovine peripheral blood mononuclear cells. 2011 Toxicol In Vitro pmid:21256206
Suzuki A and Tsutomi Y Inductions of fibroblast-like morphology and high growth activity by low-dose CPT-11 in PC12 cells: role of tenascin. 2000 Toxicol In Vitro pmid:10906440
Minervini F et al. Toxicity and apoptosis induced by the mycotoxins nivalenol, deoxynivalenol and fumonisin B1 in a human erythroleukemia cell line. 2004 Toxicol In Vitro pmid:14630058
Sancak D and Ozden S Global histone modifications in Fumonisin B1 exposure in rat kidney epithelial cells. 2015 Toxicol In Vitro pmid:26208285
Cortinovis C et al. Effects of fumonisin B1 alone and combined with deoxynivalenol or zearalenone on porcine granulosa cell proliferation and steroid production. 2014 Theriogenology pmid:24576714