fumonisin b1

fumonisin b1 is a lipid of Sphingolipids (SP) class. Fumonisin b1 is associated with abnormalities such as Infection, Kidney Diseases, Liver diseases, DERMATITIS HERPETIFORMIS, FAMILIAL and Malnutrition. The involved functions are known as Gene Expression, Anabolism, Signal, Biosynthetic Pathways and Regulation. Fumonisin b1 often locates in Body tissue, Microsomes, microsomal membrane, Protoplasm and Mitochondria. The associated genes with fumonisin b1 are Genome, P4HTM gene, FATE1 gene, BCL2 gene and TMEM132D gene. The related lipids are dihydroceramide, ceramide 1-phosphate, Sphingolipids, Fatty Acids and Palmitates.

Cross Reference

Introduction

To understand associated biological information of fumonisin b1, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with fumonisin b1?

fumonisin b1 is suspected in Infection, Kidney Diseases, Liver diseases, DERMATITIS HERPETIFORMIS, FAMILIAL, Malnutrition, Celiac Disease and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
Loading... please refresh the page if content is not showing up.

Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with fumonisin b1

MeSH term MeSH ID Detail
Pseudorabies D011557 1 associated lipids
Adenoma, Liver Cell D018248 2 associated lipids
Neuroectodermal Tumors, Primitive, Peripheral D018241 3 associated lipids
Paralysis D010243 4 associated lipids
Neuronal Ceroid-Lipofuscinoses D009472 5 associated lipids
Neural Tube Defects D009436 5 associated lipids
Hydrocephalus D006849 6 associated lipids
Scrapie D012608 7 associated lipids
Pasteurella Infections D010326 8 associated lipids
Magnesium Deficiency D008275 9 associated lipids
Per page 10 20 50 100 | Total 54

PubChem Associated disorders and diseases

What pathways are associated with fumonisin b1

Lipid pathways are not clear in current pathway databases. We organized associated pathways with fumonisin b1 through full-text articles, including metabolic pathways or pathways of biological mechanisms.

Related references are published most in these journals:

Pathway name Related literatures
Loading... please refresh the page if content is not showing up.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with fumonisin b1?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
Loading... please refresh the page if content is not showing up.

What functions are associated with fumonisin b1?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with fumonisin b1?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
Loading... please refresh the page if content is not showing up.

What genes are associated with fumonisin b1?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with fumonisin b1?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with fumonisin b1

Download all related citations
Per page 10 20 50 100 | Total 1278
Authors Title Published Journal PubMed Link
El Bawab S et al. Biochemical characterization of the reverse activity of rat brain ceramidase. A CoA-independent and fumonisin B1-insensitive ceramide synthase. 2001 J. Biol. Chem. pmid:11278489
Chalfant CE et al. FAS activation induces dephosphorylation of SR proteins; dependence on the de novo generation of ceramide and activation of protein phosphatase 1. 2001 J. Biol. Chem. pmid:11502750
Riley RT et al. Sphingolipid perturbations as mechanisms for fumonisin carcinogenesis. 2001 Environ. Health Perspect. pmid:11359699
Lemke SL et al. Deamination of fumonisin B(1) and biological assessment of reaction product toxicity. 2001 Chem. Res. Toxicol. pmid:11170503
Toxicology and carcinogenesis studies of fumonisin B1 (cas no. 116355-83-0) in F344/N rats and B6C3F1 mice (feed studies). 2001 Natl Toxicol Program Tech Rep Ser pmid:11852482
He Q et al. Fumonisin-induced tumor necrosis factor-alpha expression in a porcine kidney cell line is independent of sphingoid base accumulation induced by ceramide synthase inhibition. 2001 Toxicol. Appl. Pharmacol. pmid:11437650
Bailly JD et al. Toxicity of Fusarium moniliforme culture material containing known levels of fumonisin B1 in ducks. 2001 Toxicology pmid:11376861
Gamanya R and Sibanda L Survey of Fusarium moniliforme (F. verticillioides) and production of fumonisin B1 in cereal grains and oilseeds in Zimbabwe. 2001 Int. J. Food Microbiol. pmid:11789932
Johnson VJ and Sharma RP Gender-dependent immunosuppression following subacute exposure to fumonisin B1. 2001 Int. Immunopharmacol. pmid:11606033
Dragan YP et al. Implications of apoptosis for toxicity, carcinogenicity, and risk assessment: fumonisin B(1) as an example. 2001 Toxicol. Sci. pmid:11294969
Gelderblom WC et al. Toxicological effects in rats chronically fed low dietary levels of fumonisin B(1). 2001 Toxicology pmid:11295254
Henry MH and Wyatt RD The toxicity of fumonisin B1, B2, and B3, individually and in combination, in chicken embryos. 2001 Poult. Sci. pmid:11297276
Humphreys SH et al. A quantitative risk assessment for fumonisins B1 and B2 in US corn. 2001 Food Addit Contam pmid:11304030
Petersen A and Thorup I Preliminary evaluation of fumonisins by the Nordic countries and occurrence of fumonisins (FB1 and FB2) in corn-based foods on the Danish market. 2001 Food Addit Contam pmid:11304031
Solfrizzo M et al. Determination of fumonisins B1 and B2 in cornflakes by high performance liquid chromatography and immunoaffinity clean-up. 2001 Food Addit Contam pmid:11304032
Casado JM et al. Experimental subchronic mycotoxicoses in mice: individual and combined effects of dietary exposure to fumonisins and aflatoxin B1. 2001 Food Chem. Toxicol. pmid:11346488
Soeda S et al. Daunorubicin attenuates tumor necrosis factor-alpha-induced biosynthesis of plasminogen activator inhibitor-1 in human umbilical vein endothelial cells. 2001 Biochim. Biophys. Acta pmid:11336794
Tseng TC and Liu CY Occurrence of fumonisin B1 in maize imported into Taiwan. 2001 Int. J. Food Microbiol. pmid:11322697
Kroesen BJ et al. Induction of apoptosis through B-cell receptor cross-linking occurs via de novo generated C16-ceramide and involves mitochondria. 2001 J. Biol. Chem. pmid:11278517
Shim WB and Woloshuk CP Regulation of fumonisin B(1) biosynthesis and conidiation in Fusarium verticillioides by a cyclin-like (C-type) gene, FCC1. 2001 Appl. Environ. Microbiol. pmid:11282612
Spotti M et al. Fumonisin B1 carry-over into milk in the isolated perfused bovine udder. 2001 Vet Hum Toxicol pmid:11308118
Miguet C et al. Ceramide generation occurring during 7beta-hydroxycholesterol- and 7-ketocholesterol-induced apoptosis is caspase independent and is not required to trigger cell death. 2001 Cell Death Differ. pmid:11313706
De Girolamo A et al. Effect of processing on fumonisin concentration in corn flakes. 2001 J. Food Prot. pmid:11348004
Chelule PK et al. Exposure of rural and urban populations in KwaZulu Natal, South Africa, to fumonisin B(1) in maize. 2001 Environ. Health Perspect. pmid:11333186
Proceedings of the International Conference on the Toxicology of Fumonisin. 28-30 June 1999, Arlington, Virginia. 2001 Environ. Health Perspect. pmid:11359690
Marasas WF Discovery and occurrence of the fumonisins: a historical perspective. 2001 Environ. Health Perspect. pmid:11359691
ApSimon JW Structure, synthesis, and biosynthesis of fumonisin B1 and related compounds. 2001 Environ. Health Perspect. pmid:11359692
Haschek WM et al. Fumonisin toxicosis in swine: an overview of porcine pulmonary edema and current perspectives. 2001 Environ. Health Perspect. pmid:11359693
Voss KA et al. An overview of rodent toxicities: liver and kidney effects of fumonisins and Fusarium moniliforme. 2001 Environ. Health Perspect. pmid:11359694
Gelderblom WC et al. Toxicity of culture material of Fusarium verticillioides strain MRC 826 to nonhuman primates. 2001 Environ. Health Perspect. pmid:11359695
Howard PC et al. Fumonisin b1 carcinogenicity in a two-year feeding study using F344 rats and B6C3F1 mice. 2001 Environ. Health Perspect. pmid:11359696
Merrill AH et al. Sphingolipid metabolism: roles in signal transduction and disruption by fumonisins. 2001 Environ. Health Perspect. pmid:11359697
Gelderblom WC et al. Fumonisin-induced hepatocarcinogenesis: mechanisms related to cancer initiation and promotion. 2001 Environ. Health Perspect. pmid:11359698
Howard PC et al. Compensatory regeneration as a mechanism for renal tubule carcinogenesis of fumonisin B1 in the F344/N/Nctr BR rat. 2001 Environ. Health Perspect. pmid:11359700
Jones C et al. Analysis of fumonisin B1-induced apoptosis. 2001 Environ. Health Perspect. pmid:11359701
Miller JD Factors that affect the occurrence of fumonisin. 2001 Environ. Health Perspect. pmid:11359702
Bacon CW et al. Biological control of Fusarium moniliforme in maize. 2001 Environ. Health Perspect. pmid:11359703
Saunders DS et al. Control of fumonisin: effects of processing. 2001 Environ. Health Perspect. pmid:11359704
Duvick J Prospects for reducing fumonisin contamination of maize through genetic modification. 2001 Environ. Health Perspect. pmid:11359705
Nagy B et al. FADD null mouse embryonic fibroblasts undergo apoptosis after photosensitization with the silicon phthalocyanine Pc 4. 2001 Arch. Biochem. Biophys. pmid:11361017
Seefelder W et al. Determination of N-(carboxymethyl)fumonisin B(1) in corn products by liquid chromatography/electrospray ionization--mass spectrometry. 2001 J. Agric. Food Chem. pmid:11368569
Raynal M et al. Effects of fumonisin B1 present in Fusarium moniliforme culture material on drug metabolising enzyme activities in ducks. 2001 Toxicol. Lett. pmid:11369472
Voss KA et al. Fate of fumonisins during the production of fried tortilla chips. 2001 J. Agric. Food Chem. pmid:11410018
Gelderblom WC et al. Cancer initiation by fumonisin B(1) in rat liver--role of cell proliferation. 2001 Cancer Lett. pmid:11431101
Hartl M and Humpf HU Combined synthetic/CD strategy for the stereochemical assignment of the tricarballylic acid side chains of fumonisin B(1). 2001 J. Org. Chem. pmid:11374984
Bezombes C et al. Lysosomal sphingomyelinase is not solicited for apoptosis signaling. 2001 FASEB J. pmid:11156942
Eppley RM Preparatory isolation of mycotoxins from solid phase fungal cultures. 2001 Methods Mol. Biol. pmid:11050990
Wilkes JG and Lay JO Electrospray mass spectrometry for mycotoxin detection and purity analysis. 2001 Methods Mol. Biol. pmid:11050992
Shephard GS Liquid chromatographic method for fumonisins in corn. 2001 Methods Mol. Biol. pmid:11051000
Carlson DB et al. Fumonisin B1 promotes aflatoxin B1 and N-methyl-N'-nitro-nitrosoguanidine-initiated liver tumors in rainbow trout. 2001 Toxicol. Appl. Pharmacol. pmid:11264020
Zhang Y et al. Identification of differentially expressed genes following treatment of monkey kidney cells with the mycotoxin fumonisin B(1). 2001 Food Chem. Toxicol. pmid:11259850
Maragos CM et al. Fluorescence polarization as a means for determination of fumonisins in maize. 2001 J. Agric. Food Chem. pmid:11261998
Momany FA and Dombrink-Kurtzman MA Molecular dynamics simulations on the mycotoxin fumonisin B1. 2001 J. Agric. Food Chem. pmid:11262071
Schmidt K et al. Regulated apical secretion of zymogens in rat pancreas. Involvement of the glycosylphosphatidylinositol-anchored glycoprotein GP-2, the lectin ZG16p, and cholesterol-glycosphingolipid-enriched microdomains. 2001 J. Biol. Chem. pmid:11152672
Ziulkoski AL et al. De novo synthesis and recycling pathways of sphingomyelin in rat Sertoli cells. 2001 Biochem. Biophys. Res. Commun. pmid:11237757
Gumprecht LA et al. Species and organ specificity of fumonisin-induced endothelial alterations: potential role in porcine pulmonary edema. 2001 Toxicology pmid:11246126
van der Westhuizen L et al. The effect of repeated gavage doses of fumonisin B1 on the sphinganine and sphingosine levels in vervet monkeys. 2001 Toxicon pmid:11223085
Sharma RP et al. Decreased fumonisin hepatotoxicity in mice with a targeted deletion of tumor necrosis factor receptor 1. 2001 Toxicology pmid:11250056
Ueda N et al. Role of ceramide synthase in oxidant injury to renal tubular epithelial cells. 2001 J. Am. Soc. Nephrol. pmid:11675414
Mathur S et al. Fumonisin B(1) increases serum sphinganine concentration but does not alter serum sphingosine concentration or induce cardiovascular changes in milk-fed calves. 2001 Toxicol. Sci. pmid:11248151
Ganassi S et al. Effect of Fusarium, Paecilomyces and Trichoderma formulations against aphid Schizaphis graminum. 2001 Mycopathologia pmid:11678587
Mathur S et al. Fumonisin B(1) is hepatotoxic and nephrotoxic in milk-fed calves. 2001 Toxicol. Sci. pmid:11248152
Solfrizzo M et al. In vitro and in vivo studies to assess the effectiveness of cholestyramine as a binding agent for fumonisins. 2001 Mycopathologia pmid:11678589
Abnet CC et al. Sphingolipids as biomarkers of fumonisin exposure and risk of esophageal squamous cell carcinoma in china. 2001 Cancer Causes Control pmid:11714110
Ghosh S et al. Generation of ceramide in murine macrophages infected with Leishmania donovani alters macrophage signaling events and aids intracellular parasitic survival. 2001 Mol. Cell. Biochem. pmid:11681721
Schorling S et al. Lag1p and Lac1p are essential for the Acyl-CoA-dependent ceramide synthase reaction in Saccharomyces cerevisae. 2001 Mol. Biol. Cell pmid:11694577
Yang MS et al. Sphingomyelinase but not ceramide induces nitric oxide synthase expression in rat brain microglia. 2001 Neurosci. Lett. pmid:11567796
Liu H et al. Reaction of fumonisin with glucose prevents promotion of hepatocarcinogenesis in female F344/N rats while maintaining normal hepatic sphinganine/sphingosine ratios. 2001 J. Agric. Food Chem. pmid:11513718
Bhandari N et al. Gender-related differences in subacute fumonisin B1 hepatotoxicity in BALB/c mice. 2001 Toxicology pmid:11522378
Norred WP et al. Instability of N-acetylated fumonisin B1 (FA1) and the impact on inhibition of ceramide synthase in rat liver slices. 2001 Food Chem. Toxicol. pmid:11527566
Sewram V et al. Assessing chronic exposure to fumonisin mycotoxins: the use of hair as a suitable noninvasive matrix. 2001 J Anal Toxicol pmid:11550819
Li FQ et al. Aflatoxins and fumonisins in corn from the high-incidence area for human hepatocellular carcinoma in Guangxi, China. 2001 J. Agric. Food Chem. pmid:11513719
Torres AM et al. Fusarium species (section Liseola) and its mycotoxins in maize harvested in northern Argentina. 2001 Food Addit Contam pmid:11552751
Chourasia HK Efficacy of ammonia in detoxification of fumonisin contaminated corn. 2001 Indian J. Exp. Biol. pmid:11510139
Martins ML et al. Fumonisins B1 and B2 in black tea and medicinal plants. 2001 J. Food Prot. pmid:11510675
Kim MS et al. Fumonisin B(1) induces apoptosis in LLC-PK(1) renal epithelial cells via a sphinganine- and calmodulin-dependent pathway. 2001 Toxicol. Appl. Pharmacol. pmid:11601888
Ono EY et al. Evaluation of fumonisin-aflatoxin co-occurrence in Brazilian corn hybrids by ELISA. 2001 Food Addit Contam pmid:11469328
Omurtag GZ Determination of fumonisin B1 and B2 in corn and corn-based products in Turkey by high-performance liquid chromatography. 2001 J. Food Prot. pmid:11456195
Spotti M et al. Fumonisin B1 metabolism by bovine liver microsomes. 2001 Vet. Res. Commun. pmid:11519682
Yu CH et al. Differential effects of fumonisin B1 on cell death in cultured cells: the significance of the elevated sphinganine. 2001 Arch. Pharm. Res. pmid:11339633
Dilkin P et al. Robotic automated clean-up for detection of fumonisins B1 and B2 in corn and corn-based feed by high-performance liquid chromatography. 2001 J Chromatogr A pmid:11519801
Pozzi CR et al. Effects of prolonged oral administration of fumonisin B1 and aflatoxin B1 in rats. 2001 Mycopathologia pmid:11502059
Lawrence JF et al. Evaluation of silica- and sepharose-based immunoaffinity sorbents for sample cleanup in determination of fumonisins B1 and B2 in corn products. 2000 May-Jun J AOAC Int pmid:10868582
Lawrence JF et al. Effect of temperature and solvent composition on extraction of fumonisins B1 and B2 from corn products. 2000 May-Jun J AOAC Int pmid:10868583
Kwon OS et al. Biochemical and morphological effects of fumonisin B(1) on primary cultures of rat cerebrum. 2000 Jul-Aug Neurotoxicol Teratol pmid:10974595
Möller TE and Gustavsson HF Determination of fumonisins B1 and B2 in various maize products by a combined SAX + C18 column and immunoaffinity column. 2000 Jan-Feb J AOAC Int pmid:10693010
Riley RT and Plattner RD Fermentation, partial purification, and use of serine palmitoyltransferase inhibitors from Isaria (= Cordyceps) sinclairii. 2000 Meth. Enzymol. pmid:10563339
Henry MH et al. The toxicity of purified fumonisin B1 in broiler chicks. 2000 Poult. Sci. pmid:11055840
Wang H and Zhang X [Recent progress in the study of common fusarium mycotoxins on apoptosis of cells]. 2000 Wei Sheng Yan Jiu pmid:12725071
De Nadai C et al. Nitric oxide inhibits tumor necrosis factor-alpha-induced apoptosis by reducing the generation of ceramide. 2000 Proc. Natl. Acad. Sci. U.S.A. pmid:10792026
Constable PD et al. Ingestion of fumonisin B1-containing culture material decreases cardiac contractility and mechanical efficiency in swine. 2000 Toxicol. Appl. Pharmacol. pmid:10652243
Fredman P et al. The glycosphingolipid sulfatide in the islets of Langerhans in rat pancreas is processed through recycling: possible involvement in insulin trafficking. 2000 Glycobiology pmid:10570222
Shephard GS et al. Natural occurrence of fumonisins in corn from Iran. 2000 J. Agric. Food Chem. pmid:10820105
De Jong AJ et al. Chemical-induced apoptotic cell death in tomato cells: involvement of caspase-like proteases. 2000 Planta pmid:11089678
Jenkins GR et al. Identification of fumonisin B1 as an inhibitor of argininosuccinate synthetase using fumonisin affinity chromatography and in vitro kinetic studies. 2000 J. Biochem. Mol. Toxicol. pmid:11083085
Desjardins AE and Plattner RD Fumonisin B(1)-nonproducing strains of Fusarium verticillioides cause maize (Zea mays) ear infection and ear rot. 2000 J. Agric. Food Chem. pmid:11087553
Dombrink-Kurtzman MA et al. Effect of nixtamalization (Alkaline cooking) on fumonisin-contaminated corn for production of masa and tortillas. 2000 J. Agric. Food Chem. pmid:11087554
Machinski Júnior M and Soares LM Fumonisins B1 and B2 in Brazilian corn-based food products. 2000 Food Addit Contam pmid:11103273
Meli R et al. Effect of fumonisin B1 on inducible nitric oxide synthase and cyclooxygenase-2 in LPS-stimulated J774A.1 cells. 2000 Life Sci. pmid:11105999
Bondy GS et al. A comparison of clinical, histopathological and cell-cycle markers in rats receiving the fungal toxins fumonisin B1 or fumonisin B2 by intraperitoneal injection. 2000 Food Chem. Toxicol. pmid:11039321