fumonisin b1

fumonisin b1 is a lipid of Sphingolipids (SP) class. Fumonisin b1 is associated with abnormalities such as Infection, Kidney Diseases, Liver diseases, DERMATITIS HERPETIFORMIS, FAMILIAL and Malnutrition. The involved functions are known as Gene Expression, Anabolism, Signal, Biosynthetic Pathways and Regulation. Fumonisin b1 often locates in Body tissue, Microsomes, microsomal membrane, Protoplasm and Mitochondria. The associated genes with fumonisin b1 are Genome, P4HTM gene, FATE1 gene, BCL2 gene and TMEM132D gene. The related lipids are dihydroceramide, ceramide 1-phosphate, Sphingolipids, Fatty Acids and Palmitates.

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Introduction

To understand associated biological information of fumonisin b1, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with fumonisin b1?

fumonisin b1 is suspected in Infection, Kidney Diseases, Liver diseases, DERMATITIS HERPETIFORMIS, FAMILIAL, Malnutrition, Celiac Disease and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with fumonisin b1

MeSH term MeSH ID Detail
Adenocarcinoma D000230 166 associated lipids
Adenoma D000236 40 associated lipids
Asthma D001249 52 associated lipids
Body Weight D001835 333 associated lipids
Brain Diseases D001927 27 associated lipids
Carcinoma D002277 18 associated lipids
Cardiovascular Diseases D002318 24 associated lipids
Cell Transformation, Neoplastic D002471 126 associated lipids
Choline Deficiency D002796 16 associated lipids
Cleft Palate D002972 9 associated lipids
Per page 10 20 50 100 | Total 54

PubChem Associated disorders and diseases

What pathways are associated with fumonisin b1

Lipid pathways are not clear in current pathway databases. We organized associated pathways with fumonisin b1 through full-text articles, including metabolic pathways or pathways of biological mechanisms.

Related references are published most in these journals:

Pathway name Related literatures
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PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with fumonisin b1?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with fumonisin b1?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with fumonisin b1?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with fumonisin b1?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with fumonisin b1?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with fumonisin b1

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Authors Title Published Journal PubMed Link
Gopee NV et al. Fumonisin B1-induced apoptosis is associated with delayed inhibition of protein kinase C, nuclear factor-kappaB and tumor necrosis factor alpha in LLC-PK1 cells. 2003 Chem. Biol. Interact. pmid:14597127
Bhandari N et al. Modulation of selected cell signaling genes in mouse liver by fumonisin B1. 2002 Chem. Biol. Interact. pmid:11879819
Tran ST et al. Sphinganine to sphingosine ratio and predictive biochemical markers of fumonisin B1 exposure in ducks. 2003 Chem. Biol. Interact. pmid:12902153
Tardieu D et al. Tissue persistence of fumonisin B1 in ducks and after exposure to a diet containing the maximum European tolerance for fumonisins in avian feeds. 2009 Chem. Biol. Interact. pmid:19559689
Orsi RB et al. Acute toxicity of a single gavage dose of fumonisin B1 in rabbits. 2009 Chem. Biol. Interact. pmid:19330885
Johnson VJ et al. Increased susceptibility of renal epithelial cells to TNFalpha-induced apoptosis following treatment with fumonisin B1. 2003 Chem. Biol. Interact. pmid:12732456
Dilkin P et al. Toxicokinetics and toxicological effects of single oral dose of fumonisin B1 containing Fusarium verticillioides culture material in weaned piglets. 2010 Chem. Biol. Interact. pmid:20338158
Sharma N et al. Sphingosine kinase activity confers resistance to apoptosis by fumonisin B1 in human embryonic kidney (HEK-293) cells. 2004 Chem. Biol. Interact. pmid:15607760
Tardieu D et al. Effects of fumonisins on liver and kidney sphinganine and the sphinganine to sphingosine ratio during chronic exposure in ducks. 2006 Chem. Biol. Interact. pmid:16412405
Tran ST et al. Serum sphinganine and the sphinganine to sphingosine ratio as a biomarker of dietary fumonisins during chronic exposure in ducks. 2006 Chem. Biol. Interact. pmid:16413517
Lemke SL et al. Deamination of fumonisin B(1) and biological assessment of reaction product toxicity. 2001 Chem. Res. Toxicol. pmid:11170503
Nácher-Mestre J et al. Occurrence and potential transfer of mycotoxins in gilthead sea bream and Atlantic salmon by use of novel alternative feed ingredients. 2015 Chemosphere pmid:25754010
Kawano Y et al. Regulation of interleukin-1alpha and tumor necrosis factor-alpha-induced interleukin-8 production by amnion-derived (WISH) cells. 2012 Clin Exp Obstet Gynecol pmid:22675954
Theumer MG et al. Immunobiological effects of fumonisin B1 in experimental subchronic mycotoxicoses in rats. 2002 Clin. Diagn. Lab. Immunol. pmid:11777845
Zadeh MH and Shahdadi H Nanocellulose coated with various free fatty acids can adsorb fumonisin B1, and decrease its toxicity. 2015 Colloids Surf B Biointerfaces pmid:26142625
Jebali A et al. Modification of nanocellulose by poly-lysine can inhibit the effect of fumonisin B1 on mouse liver cells. 2015 Colloids Surf B Biointerfaces pmid:25601749
Daković A et al. Influence of natural zeolitic tuff and organozeolites surface charge on sorption of ionizable fumonisin B(1). 2010 Colloids Surf B Biointerfaces pmid:20004084
Theumer MG et al. The lipid-mediated hypothesis of fumonisin B1 toxicodynamics tested in model membranes. 2008 Colloids Surf B Biointerfaces pmid:18296035
Bhandari N et al. Temporal expression of fumonisin B(1)-induced tumor necrosis factor-alpha and interferon gamma in mice. 2002 Comp. Biochem. Physiol. C Toxicol. Pharmacol. pmid:11879779
Tsunoda M et al. Fumonisin B1-induced increases in neurotransmitter metabolite levels in different brain regions of BALB/c mice. 1998 Comp. Biochem. Physiol. C, Pharmacol. Toxicol. Endocrinol. pmid:9827064