| MeSH term | MeSH ID | Detail |
|---|---|---|
| Adenocarcinoma | D000230 | 166 associated lipids |
| Adenoma | D000236 | 40 associated lipids |
| Asthma | D001249 | 52 associated lipids |
| Body Weight | D001835 | 333 associated lipids |
| Brain Diseases | D001927 | 27 associated lipids |
| Carcinoma | D002277 | 18 associated lipids |
| Cardiovascular Diseases | D002318 | 24 associated lipids |
| Cell Transformation, Neoplastic | D002471 | 126 associated lipids |
| Choline Deficiency | D002796 | 16 associated lipids |
| Cleft Palate | D002972 | 9 associated lipids |
fumonisin b1
fumonisin b1 is a lipid of Sphingolipids (SP) class. Fumonisin b1 is associated with abnormalities such as Infection, Kidney Diseases, Liver diseases, DERMATITIS HERPETIFORMIS, FAMILIAL and Malnutrition. The involved functions are known as Gene Expression, Anabolism, Signal, Biosynthetic Pathways and Regulation. Fumonisin b1 often locates in Body tissue, Microsomes, microsomal membrane, Protoplasm and Mitochondria. The associated genes with fumonisin b1 are Genome, P4HTM gene, FATE1 gene, BCL2 gene and TMEM132D gene. The related lipids are dihydroceramide, ceramide 1-phosphate, Sphingolipids, Fatty Acids and Palmitates.
Cross Reference
Introduction
To understand associated biological information of fumonisin b1, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with fumonisin b1?
fumonisin b1 is suspected in Infection, Kidney Diseases, Liver diseases, DERMATITIS HERPETIFORMIS, FAMILIAL, Malnutrition, Celiac Disease and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with fumonisin b1
PubChem Associated disorders and diseases
What pathways are associated with fumonisin b1
Lipid pathways are not clear in current pathway databases. We organized associated pathways with fumonisin b1 through full-text articles, including metabolic pathways or pathways of biological mechanisms.
Related references are published most in these journals:
| Pathway name | Related literatures |
|---|
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PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with fumonisin b1?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
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What functions are associated with fumonisin b1?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with fumonisin b1?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
|---|
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What genes are associated with fumonisin b1?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with fumonisin b1?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with fumonisin b1
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Rentz SS et al. | Inhibition of sphingolipid biosynthesis decreases phosphorylated ERK2 in LLC-PK1 cells. | 2005 | Food Chem. Toxicol. | pmid:15582204 |
| Flynn TJ et al. | Assessment of the embryotoxic potential of the total hydrolysis product of fumonisin B1 using cultured organogenesis-staged rat embryos. | 1997 | Food Chem. Toxicol. | pmid:9449218 |
| Ueno Y et al. | Fumonisins as a possible contributory risk factor for primary liver cancer: a 3-year study of corn harvested in Haimen, China, by HPLC and ELISA. | 1997 | Food Chem. Toxicol. | pmid:9449219 |
| Riedel S et al. | Induction of an altered lipid phenotype by two cancer promoting treatments in rat liver. | 2015 | Food Chem. Toxicol. | pmid:25656646 |
| Bondy GS et al. | Toxicity of fumonisin B1 to B6C3F1 mice: a 14-day gavage study. | 1997 Oct-Nov | Food Chem. Toxicol. | pmid:9463532 |
| Hlywka JJ et al. | The use of the chicken embryo screening test and brine shrimp (Artemia salina) bioassays to assess the toxicity of fumonisin B1 mycotoxin. | 1997 Oct-Nov | Food Chem. Toxicol. | pmid:9463533 |
| Sheu CW et al. | Lack of transforming activity of fumonisin B1 in BALB/3T3 A31-1-1 mouse embryo cells. | 1996 | Food Chem. Toxicol. | pmid:8883477 |
| Osuchowski MF et al. | Endotoxin exposure alters brain and liver effects of fumonisin B1 in BALB/c mice: implication of blood brain barrier. | 2005 | Food Chem. Toxicol. | pmid:15913876 |
| Szabó A et al. | Individual and combined haematotoxic effects of fumonisin B(1) and T-2 mycotoxins in rabbits. | 2014 | Food Chem. Toxicol. | pmid:25092395 |
| Bouhet S et al. | Mycotoxin fumonisin B1 selectively down-regulates the basal IL-8 expression in pig intestine: in vivo and in vitro studies. | 2006 | Food Chem. Toxicol. | pmid:16843581 |
| Gelderblom WC et al. | Effect of fumonisin B1 on the levels and fatty acid composition of selected lipids in rat liver in vivo. | 1997 | Food Chem. Toxicol. | pmid:9301647 |
| Marina Martins H et al. | Fumonisins and deoxynivalenol in corn-based food products in Portugal. | 2008 | Food Chem. Toxicol. | pmid:18486293 |
| van der Westhuizen L et al. | Sphinganine/sphingosine ratio in plasma and urine as a possible biomarker for fumonisin exposure in humans in rural areas of Africa. | 1999 | Food Chem. Toxicol. | pmid:10654591 |
| Aly SE et al. | Application of adsorbent agents technology in the removal of aflatoxin B(1) and fumonisin B(1) from malt extract. | 2004 | Food Chem. Toxicol. | pmid:15350680 |
| Norred WP et al. | Effectiveness of ammonia treatment in detoxification of fumonisin-contaminated corn. | 1991 | Food Chem. Toxicol. | pmid:1765326 |
| Collins TF et al. | Effects of fumonisin B1 in pregnant rats. | 1998 | Food Chem. Toxicol. | pmid:9662415 |
| Norred WP et al. | Effects of selected secondary metabolites of Fusarium moniliforme on unscheduled synthesis of DNA by rat primary hepatocytes. | 1992 | Food Chem. Toxicol. | pmid:1618447 |
| McKean C et al. | Comparative acute and combinative toxicity of aflatoxin B1 and fumonisin B1 in animals and human cells. | 2006 | Food Chem. Toxicol. | pmid:16427177 |
| Voss KA et al. | Hepatotoxicity and renal toxicity in rats of corn samples associated with field cases of equine leukoencephalomalacia. | 1989 | Food Chem. Toxicol. | pmid:2714720 |
| Karbancioglu-Güler F and Heperkan D | Natural occurrence of fumonisin B1 in dried figs as an unexpected hazard. | 2009 | Food Chem. Toxicol. | pmid:19032973 |
| Marnewick JL et al. | Chemoprotective properties of rooibos (Aspalathus linearis), honeybush (Cyclopia intermedia) herbal and green and black (Camellia sinensis) teas against cancer promotion induced by fumonisin B1 in rat liver. | 2009 | Food Chem. Toxicol. | pmid:19041360 |
| Cetin Y and Bullerman LB | Cytotoxicity of Fusarium mycotoxins to mammalian cell cultures as determined by the MTT bioassay. | 2005 | Food Chem. Toxicol. | pmid:15778016 |
| Shephard GS et al. | Biliary excretion of the mycotoxin fumonisin B1 in rats. | 1994 | Food Chem. Toxicol. | pmid:8206448 |
| Meca G et al. | Isolation, purification, LC-MS/MS characterization and reactive oxygen species induced by fumonisin B1 in VERO cells. | 2010 | Food Chem. Toxicol. | pmid:20655973 |
| Denli M et al. | Efficacy of AdiDetoxâ„¢ in reducing the toxicity of fumonisin B1 in rats. | 2015 | Food Chem. Toxicol. | pmid:25660482 |
| Hahn I et al. | Effects of orally administered fumonisin Bâ‚ (FBâ‚), partially hydrolysed FBâ‚, hydrolysed FBâ‚ and N-(1-deoxy-D-fructos-1-yl) FBâ‚ on the sphingolipid metabolism in rats. | 2015 | Food Chem. Toxicol. | pmid:25475052 |
| Shephard GS et al. | Determination of the mycotoxin fumonisin B1 and identification of its partially hydrolysed metabolites in the faeces of non-human primates. | 1994 | Food Chem. Toxicol. | pmid:8132161 |
| Collins TF et al. | Effects of fumonisin B1 in pregnant rats. Part 2. | 1998 | Food Chem. Toxicol. | pmid:9734718 |
| Chamberlain WJ et al. | Levels of fumonisin B1 in corn naturally contaminated with aflatoxins. | 1993 | Food Chem. Toxicol. | pmid:8282284 |
| Persson EC et al. | Fumonisin B1 and risk of hepatocellular carcinoma in two Chinese cohorts. | 2012 | Food Chem. Toxicol. | pmid:22142693 |
| Bondy G et al. | Effects of long term exposure to the mycotoxin fumonisin B1 in p53 heterozygous and p53 homozygous transgenic mice. | 2012 | Food Chem. Toxicol. | pmid:22841953 |
| Wan LY et al. | Individual and combined cytotoxic effects of Fusarium toxins (deoxynivalenol, nivalenol, zearalenone and fumonisins B1) on swine jejunal epithelial cells. | 2013 | Food Chem. Toxicol. | pmid:23562706 |
| Singh MP and Kang SC | Endoplasmic reticulum stress-mediated autophagy activation attenuates fumonisin B1 induced hepatotoxicity in vitro and in vivo. | 2017 | Food Chem. Toxicol. | pmid:29097114 |
| Souto PCMC et al. | Determination of fumonisin B levels in body fluids and hair from piglets fed fumonisin B-contaminated diets. | 2017 | Food Chem. Toxicol. | pmid:28733235 |
| He Q et al. | Myriocin prevents fumonisin B1-induced sphingoid base accumulation in mice liver without ameliorating hepatotoxicity. | 2005 | Food Chem. Toxicol. | pmid:15811577 |
| Gelderblom WC et al. | Effect of fumonisin B1 on protein and lipid synthesis in primary rat hepatocytes. | 1996 | Food Chem. Toxicol. | pmid:8641662 |
| Hartl M and Humpf HU | Toxicity assessment of fumonisins using the brine shrimp (Artemia salina) bioassay. | 2000 | Food Chem. Toxicol. | pmid:11033198 |
| Escrivá L et al. | In vivo toxicity studies of fusarium mycotoxins in the last decade: a review. | 2015 | Food Chem. Toxicol. | pmid:25680507 |
| Ciacci-Zanella JR et al. | Characterization of cell-cycle arrest by fumonisin B1 in CV-1 cells. | 1998 Sep-Oct | Food Chem. Toxicol. | pmid:9737426 |
| Stockmann-Juvala H et al. | Effects of fumonisin B(1) on the expression of cytokines and chemokines in human dendritic cells. | 2008 | Food Chem. Toxicol. | pmid:18194833 |
| Mary VS et al. | Effects of aflatoxin Bâ‚, fumonisin Bâ‚ and their mixture on the aryl hydrocarbon receptor and cytochrome P450 1A induction. | 2015 | Food Chem. Toxicol. | pmid:25449202 |
| Bondy GS et al. | A comparison of clinical, histopathological and cell-cycle markers in rats receiving the fungal toxins fumonisin B1 or fumonisin B2 by intraperitoneal injection. | 2000 | Food Chem. Toxicol. | pmid:11039321 |
| van der Westhuizen L et al. | Inhibition of sphingolipid biosynthesis in rat primary hepatocyte cultures by fumonisin B1 and other structurally related compounds. | 1998 | Food Chem. Toxicol. | pmid:9674957 |
| Zhang Y et al. | Identification of differentially expressed genes following treatment of monkey kidney cells with the mycotoxin fumonisin B(1). | 2001 | Food Chem. Toxicol. | pmid:11259850 |
| Lerda D et al. | Fumonisins in foods from Cordoba (Argentina), presence and genotoxicity. | 2005 | Food Chem. Toxicol. | pmid:15778008 |
| Gelderblom WC et al. | Structure-activity relationships of fumonisins in short-term carcinogenesis and cytotoxicity assays. | 1993 | Food Chem. Toxicol. | pmid:8514212 |
| Enongene EN et al. | Disruption of sphingolipid metabolism in small intestines, liver and kidney of mice dosed subcutaneously with fumonisin B(1). | 2000 | Food Chem. Toxicol. | pmid:10930700 |
| Esposito F et al. | Exposure assessment to fumonisins B, B and B through consumption of gluten-free foodstuffs intended for people affected by celiac disease. | 2016 | Food Chem. Toxicol. | pmid:27746327 |
| Cawood ME et al. | Interaction of 14C-labelled fumonisin B mycotoxins with primary rat hepatocyte cultures. | 1994 | Food Chem. Toxicol. | pmid:8045475 |
| Galvano F et al. | DNA damage in human fibroblasts exposed to fumonisin B(1). | 2002 | Food Chem. Toxicol. | pmid:11731033 |
| Norred WP et al. | Instability of N-acetylated fumonisin B1 (FA1) and the impact on inhibition of ceramide synthase in rat liver slices. | 2001 | Food Chem. Toxicol. | pmid:11527566 |
| Qian G et al. | Sequential dietary exposure to aflatoxin B1 and fumonisin B1 in F344 rats increases liver preneoplastic changes indicative of a synergistic interaction. | 2016 | Food Chem. Toxicol. | pmid:27430420 |
| Hinojo MJ et al. | Fumonisin production in rice cultures of Fusarium verticillioides under different incubation conditions using an optimized analytical method. | 2006 | Food Microbiol. | pmid:16942995 |
| Ayasolla K et al. | Inflammatory mediator and beta-amyloid (25-35)-induced ceramide generation and iNOS expression are inhibited by vitamin E. | 2004 | Free Radic. Biol. Med. | pmid:15223066 |
| Stockmann-Juvala H et al. | Oxidative stress induced by fumonisin B1 in continuous human and rodent neural cell cultures. | 2004 | Free Radic. Res. | pmid:15621711 |
| Tryphonas H et al. | Effects of fumonisin B1 on the immune system of sprague-dawley rats following a 14-day oral (gavage) exposure. | 1997 | Fundam Appl Toxicol | pmid:9325027 |
| LaBorde JB et al. | Lack of embryotoxicity of fumonisin B1 in New Zealand white rabbits. | 1997 | Fundam Appl Toxicol | pmid:9398494 |
| Casteel SW et al. | Chronic effects of dietary fumonisin on the heart and pulmonary vasculature of swine. | 1994 | Fundam Appl Toxicol | pmid:7867903 |
| Voss KA et al. | Subchronic feeding study of the mycotoxin fumonisin B1 in B6C3F1 mice and Fischer 344 rats. | 1995 | Fundam Appl Toxicol | pmid:7713333 |
| Guo L et al. | FvSO regulates vegetative hyphal fusion, asexual growth, fumonisin B1 production, and virulence in Fusarium verticillioides. | 2015 | Fungal Biol | pmid:26615739 |
| Bluhm BH and Woloshuk CP | Fck1, a C-type cyclin-dependent kinase, interacts with Fcc1 to regulate development and secondary metabolism in Fusarium verticillioides. | 2006 | Fungal Genet. Biol. | pmid:16504555 |
| Proctor RH et al. | A polyketide synthase gene required for biosynthesis of fumonisin mycotoxins in Gibberella fujikuroi mating population A. | 1999 | Fungal Genet. Biol. | pmid:10413619 |
| Han J et al. | Mechanism of action of AMP-jsa9, a LI-F-type antimicrobial peptide produced by Paenibacillus polymyxa JSa-9, against Fusarium moniliforme. | 2017 | Fungal Genet. Biol. | pmid:28512016 |
| Kim H and Woloshuk CP | Role of AREA, a regulator of nitrogen metabolism, during colonization of maize kernels and fumonisin biosynthesis in Fusarium verticillioides. | 2008 | Fungal Genet. Biol. | pmid:18440841 |
| Prasitchoke P et al. | Identification and characterization of a very long-chain fatty acid elongase gene in the methylotrophic yeast, Hansenula polymorpha. | 2007 | Gene | pmid:17236726 |
| Fredman P et al. | The glycosphingolipid sulfatide in the islets of Langerhans in rat pancreas is processed through recycling: possible involvement in insulin trafficking. | 2000 | Glycobiology | pmid:10570222 |
| Thomas CP et al. | Gangliosides protect human melanoma cells from ionizing radiation-induced clonogenic cell death. | 1996 | Glycoconj. J. | pmid:8781968 |
| Zacharias C et al. | The effect of fumonisin B1 on developing chick embryos: correlation between de novo sphingolipid biosynthesis and gross morphological changes. | 1996 | Glycoconj. J. | pmid:8737241 |
| Gelderblom WC and Marasas WF | Controversies in fumonisin mycotoxicology and risk assessment. | 2012 | Hum Exp Toxicol | pmid:21278198 |
| Domijan A et al. | Early toxic effects of fumonisin B1 in rat liver. | 2008 | Hum Exp Toxicol | pmid:19273544 |
| Stockmann-Juvala H and Savolainen K | A review of the toxic effects and mechanisms of action of fumonisin B1. | 2008 | Hum Exp Toxicol | pmid:19244287 |
| Yao ZG et al. | Effects of fumonisin B1 on HLA class I antigen presentation and processing pathway in GES-1 cells in vitro. | 2011 | Hum Exp Toxicol | pmid:20507871 |
| Toxins derived from Fusarium moniliforme: fumonisins B1 and B2 and fusarin C. | 1993 | IARC Monogr Eval Carcinog Risks Hum | pmid:8411627 | |
| Guzman RE et al. | Dietary Fusarium moniliforme culture material induces in vitro tumor necrosis factor-alpha like activity in the sera of swine. | 1997 | Immunopharmacol Immunotoxicol | pmid:9130010 |
| Qureshi MA et al. | Fusarium proliferatum culture material alters several production and immune performance parameters in White Leghorn chickens. | 1995 | Immunopharmacol Immunotoxicol | pmid:8537614 |
| Dombrink-Kurtzman MA et al. | Activation of rat splenic macrophage and lymphocyte functions by fumonisin B1. | 2000 | Immunopharmacology | pmid:10996037 |
| Fornelli F et al. | Cytotoxicity induced by nivalenol, deoxynivalenol, and fumonisin B1 in the SF-9 insect cell line. | 2004 May-Jun | In Vitro Cell. Dev. Biol. Anim. | pmid:15479121 |
| Chourasia HK | Efficacy of ammonia in detoxification of fumonisin contaminated corn. | 2001 | Indian J. Exp. Biol. | pmid:11510139 |
| Hatch GM and McClarty G | Phospholipid composition of purified Chlamydia trachomatis mimics that of the eucaryotic host cell. | 1998 | Infect. Immun. | pmid:9673255 |
| Delgado JE and Wolt JD | Fumonisin B1 toxicity in grower-finisher pigs: a comparative analysis of genetically engineered Bt corn and non-Bt corn by using quantitative dietary exposure assessment modeling. | 2011 | Int J Environ Res Public Health | pmid:21909298 |
| Cirlini M et al. | Hydrolysed fumonisin B1 and N-(deoxy-D-fructos-1-yl)-fumonisin B1: stability and catabolic fate under simulated human gastrointestinal conditions. | 2015 | Int J Food Sci Nutr | pmid:25472591 |
| Yao J et al. | Ultraviolet (UV) and hydrogen peroxide activate ceramide-ER stress-AMPK signaling axis to promote retinal pigment epithelium (RPE) cell apoptosis. | 2013 | Int J Mol Sci | pmid:23685869 |
| McKeague M et al. | Screening and initial binding assessment of fumonisin b(1) aptamers. | 2010 | Int J Mol Sci | pmid:21614178 |
| Wang Y et al. | Characterization and comparison of Fumonisin B(1)-protein conjugates by six methods. | 2012 | Int J Mol Sci | pmid:22312240 |
| Ribeiro DH et al. | Effects of aflatoxin B(1) and fumonisin B(1) on the viability and induction of apoptosis in rat primary hepatocytes. | 2010 | Int J Mol Sci | pmid:20480051 |
| Johnson VJ and Sharma RP | Gender-dependent immunosuppression following subacute exposure to fumonisin B1. | 2001 | Int. Immunopharmacol. | pmid:11606033 |
| Odhav B et al. | Modulating effects of fumonisin B1 and ochratoxin A on leukocytes and messenger cytokines of the human immune system. | 2008 | Int. Immunopharmacol. | pmid:18442783 |
| Dresden-Osborne C and Noblet GP | Fumonisin B1 affects viability and alters nitric oxide production of a murine macrophage cell line. | 2002 | Int. Immunopharmacol. | pmid:12349946 |
| Li Y et al. | The immunosuppressive characteristics of FB by inhibition of maturation and function of BMDCs. | 2017 | Int. Immunopharmacol. | pmid:28432936 |
| Domijan AM and Abramov AY | Fumonisin B1 inhibits mitochondrial respiration and deregulates calcium homeostasis--implication to mechanism of cell toxicity. | 2011 | Int. J. Biochem. Cell Biol. | pmid:21397036 |
| Koyanagi S et al. | Elevation of de novo ceramide synthesis in tumor masses and the role of microsomal dihydroceramide synthase. | 2003 | Int. J. Cancer | pmid:12672022 |
| DiPietrantonio AM et al. | Regulation of G1/S transition and induction of apoptosis in HL-60 leukemia cells by fenretinide (4HPR). | 1998 | Int. J. Cancer | pmid:9724094 |
| Dambolena JS et al. | Antifumonisin activity of natural phenolic compounds A structure-property-activity relationship study. | 2011 | Int. J. Food Microbiol. | pmid:21195498 |
| Gamanya R and Sibanda L | Survey of Fusarium moniliforme (F. verticillioides) and production of fumonisin B1 in cereal grains and oilseeds in Zimbabwe. | 2001 | Int. J. Food Microbiol. | pmid:11789932 |
| Sweeney MJ and Dobson AD | Mycotoxin production by Aspergillus, Fusarium and Penicillium species. | 1998 | Int. J. Food Microbiol. | pmid:9801191 |
| Samapundo S et al. | The influence of modified atmospheres and their interaction with water activity on the radial growth and fumonisin B(1) production of Fusarium verticillioides and F. proliferatum on corn. Part I: the effect of initial headspace carbon dioxide concentration. | 2007 | Int. J. Food Microbiol. | pmid:17084933 |
| Samapundo S et al. | The influence of modified atmospheres and their interaction with water activity on the radial growth and fumonisin B(1) production of Fusarium verticillioides and F. proliferatum on corn. Part II: The effect of initial headspace oxygen concentration. | 2007 | Int. J. Food Microbiol. | pmid:17084934 |
| MarÃn S et al. | Two-dimensional profiles of fumonisin B1 production by Fusarium moniliforme and Fusarium proliferatum in relation to environmental factors and potential for modelling toxin formation in maize grain. | 1999 | Int. J. Food Microbiol. | pmid:10574091 |
| Lino CM et al. | Occurrence of fumonisins B1 and B2 in broa, typical Portuguese maize bread. | 2007 | Int. J. Food Microbiol. | pmid:17604863 |
| Samsudin NI et al. | Efficacy of fungal and bacterial antagonists for controlling growth, FUM1 gene expression and fumonisin B production by Fusarium verticillioides on maize cobs of different ripening stages. | 2017 | Int. J. Food Microbiol. | pmid:28213318 |