fumonisin b1

fumonisin b1 is a lipid of Sphingolipids (SP) class. Fumonisin b1 is associated with abnormalities such as Infection, Kidney Diseases, Liver diseases, DERMATITIS HERPETIFORMIS, FAMILIAL and Malnutrition. The involved functions are known as Gene Expression, Anabolism, Signal, Biosynthetic Pathways and Regulation. Fumonisin b1 often locates in Body tissue, Microsomes, microsomal membrane, Protoplasm and Mitochondria. The associated genes with fumonisin b1 are Genome, P4HTM gene, FATE1 gene, BCL2 gene and TMEM132D gene. The related lipids are dihydroceramide, ceramide 1-phosphate, Sphingolipids, Fatty Acids and Palmitates.

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Introduction

To understand associated biological information of fumonisin b1, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with fumonisin b1?

fumonisin b1 is suspected in Infection, Kidney Diseases, Liver diseases, DERMATITIS HERPETIFORMIS, FAMILIAL, Malnutrition, Celiac Disease and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with fumonisin b1

MeSH term MeSH ID Detail
Adenocarcinoma D000230 166 associated lipids
Adenoma D000236 40 associated lipids
Asthma D001249 52 associated lipids
Body Weight D001835 333 associated lipids
Brain Diseases D001927 27 associated lipids
Carcinoma D002277 18 associated lipids
Cardiovascular Diseases D002318 24 associated lipids
Cell Transformation, Neoplastic D002471 126 associated lipids
Choline Deficiency D002796 16 associated lipids
Cleft Palate D002972 9 associated lipids
Per page 10 20 50 100 | Total 54

PubChem Associated disorders and diseases

What pathways are associated with fumonisin b1

Lipid pathways are not clear in current pathway databases. We organized associated pathways with fumonisin b1 through full-text articles, including metabolic pathways or pathways of biological mechanisms.

Related references are published most in these journals:

Pathway name Related literatures
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PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with fumonisin b1?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with fumonisin b1?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with fumonisin b1?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with fumonisin b1?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with fumonisin b1?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with fumonisin b1

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Authors Title Published Journal PubMed Link
Deshmukh S et al. Effects of Fusarium moniliforme culture material containing known levels of fumonisin B1 on progress of Salmonella Gallinarum infection in Japanese quail: clinical signs and hematologic studies. 2005 Avian Dis. pmid:16094834
Brown TP et al. Fumonisin mycotoxicosis in broilers: performance and pathology. 1992 Apr-Jun Avian Dis. pmid:1627116
Espada Y et al. Fumonisin mycotoxicosis in broilers. Weights and serum chemistry modifications. 1994 Jul-Sep Avian Dis. pmid:7832697
Grimes JL et al. Paralysis of undetermined origin in bobwhite quail. 1993 Apr-Jun Avian Dis. pmid:8363521
Sharma D et al. Toxic interaction between fumonisin B1 and moniliformin for cardiac lesions in Japanese quail. 2012 Avian Dis. pmid:23050472
Deshmukh S et al. Pathologic changes in extrahepatic organs and agglutinin response to Salmonella Gallinarum infection in Japanese quail fed Fusarium verticillioides culture material containing known levels of fumonisin B1. 2007 Avian Dis. pmid:17992930
Bermudez AJ et al. The chronic effects of Fusarium moniliforme culture material, containing known levels of fumonisin B1, in turkeys. 1996 Jan-Mar Avian Dis. pmid:8713041
Bermudez AJ et al. Effects of Fusarium moniliforme culture material containing known levels of fumonisin B1 in ducklings. 1995 Oct-Dec Avian Dis. pmid:8719224
Klarić MS et al. Lipid peroxidation and glutathione levels in porcine kidney PK15 cells after individual and combined treatment with fumonisin B(1), beauvericin and ochratoxin A. 2007 Basic Clin. Pharmacol. Toxicol. pmid:17309518
Wattenberg EV et al. Activation of mitogen-activated protein kinase by the carcinogenic mycotoxin fumonisin B1. 1996 Biochem. Biophys. Res. Commun. pmid:8878562
Yin JJ et al. Effects of fumonisin B1 on oxygen transport in membranes. 1996 Biochem. Biophys. Res. Commun. pmid:8769126
Jiang L et al. Preferential involvement of both ROS and ceramide in fenretinide-induced apoptosis of HL60 rather than NB4 and U937 cells. 2011 Biochem. Biophys. Res. Commun. pmid:21237137
Akao Y et al. Ceramide accumulation is independent of camptothecin-induced apoptosis in prostate cancer LNCaP cells. 2002 Biochem. Biophys. Res. Commun. pmid:12051721
Rother J et al. Biosynthesis of sphingolipids: dihydroceramide and not sphinganine is desaturated by cultured cells. 1992 Biochem. Biophys. Res. Commun. pmid:1449467
Kobayashi Y et al. The critical role of spinal ceramide in the development of partial sciatic nerve ligation-induced neuropathic pain in mice. 2012 Biochem. Biophys. Res. Commun. pmid:22503971
Ganguly S et al. Metabolic depletion of sphingolipids enhances the mobility of the human serotonin1A receptor. 2011 Biochem. Biophys. Res. Commun. pmid:21726540
Fukuda H et al. Inhibition of protein serine/threonine phosphatases by fumonisin B1, a mycotoxin. 1996 Biochem. Biophys. Res. Commun. pmid:8602837
Inooka S and Toyokuni T Sphingosine transfer in cell-to-cell interaction. 1996 Biochem. Biophys. Res. Commun. pmid:8579607
Ziulkoski AL et al. De novo synthesis and recycling pathways of sphingomyelin in rat Sertoli cells. 2001 Biochem. Biophys. Res. Commun. pmid:11237757
Bionda C et al. Subcellular compartmentalization of ceramide metabolism: MAM (mitochondria-associated membrane) and/or mitochondria? 2004 Biochem. J. pmid:15144238