fumonisin b1

fumonisin b1 is a lipid of Sphingolipids (SP) class. Fumonisin b1 is associated with abnormalities such as Infection, Kidney Diseases, Liver diseases, DERMATITIS HERPETIFORMIS, FAMILIAL and Malnutrition. The involved functions are known as Gene Expression, Anabolism, Signal, Biosynthetic Pathways and Regulation. Fumonisin b1 often locates in Body tissue, Microsomes, microsomal membrane, Protoplasm and Mitochondria. The associated genes with fumonisin b1 are Genome, P4HTM gene, FATE1 gene, BCL2 gene and TMEM132D gene. The related lipids are dihydroceramide, ceramide 1-phosphate, Sphingolipids, Fatty Acids and Palmitates.

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Introduction

To understand associated biological information of fumonisin b1, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with fumonisin b1?

fumonisin b1 is suspected in Infection, Kidney Diseases, Liver diseases, DERMATITIS HERPETIFORMIS, FAMILIAL, Malnutrition, Celiac Disease and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with fumonisin b1

MeSH term MeSH ID Detail
Adenocarcinoma D000230 166 associated lipids
Adenoma D000236 40 associated lipids
Asthma D001249 52 associated lipids
Body Weight D001835 333 associated lipids
Brain Diseases D001927 27 associated lipids
Carcinoma D002277 18 associated lipids
Cardiovascular Diseases D002318 24 associated lipids
Cell Transformation, Neoplastic D002471 126 associated lipids
Choline Deficiency D002796 16 associated lipids
Cleft Palate D002972 9 associated lipids
Per page 10 20 50 100 | Total 54

PubChem Associated disorders and diseases

What pathways are associated with fumonisin b1

Lipid pathways are not clear in current pathway databases. We organized associated pathways with fumonisin b1 through full-text articles, including metabolic pathways or pathways of biological mechanisms.

Related references are published most in these journals:

Pathway name Related literatures
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PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with fumonisin b1?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with fumonisin b1?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with fumonisin b1?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with fumonisin b1?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with fumonisin b1?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with fumonisin b1

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Per page 10 20 50 100 | Total 1278
Authors Title Published Journal PubMed Link
Bouhet S et al. The mycotoxin fumonisin B1 alters the proliferation and the barrier function of porcine intestinal epithelial cells. 2004 Toxicol. Sci. pmid:14600282
Wan LY et al. Modulation of mucin mRNA (MUC5AC and MUC5B) expression and protein production and secretion in Caco-2/HT29-MTX co-cultures following exposure to individual and combined Fusarium mycotoxins. 2014 Toxicol. Sci. pmid:24496642
Ferrante MC et al. Effect of fumonisin B1 on structure and function of macrophage plasma membrane. 2002 Toxicol. Lett. pmid:11888701
Bondy GS et al. Retrospective evaluation of serum ornithine carbamyltransferase activity as an index of hepatotoxicity in toxicological studies with rats. 2000 Toxicol. Lett. pmid:10713481
Raynal M et al. Effects of fumonisin B1 present in Fusarium moniliforme culture material on drug metabolising enzyme activities in ducks. 2001 Toxicol. Lett. pmid:11369472
Wan LY et al. Individual and combined effects of Fusarium toxins on the mRNA expression of pro-inflammatory cytokines in swine jejunal epithelial cells. 2013 Toxicol. Lett. pmid:23688591
Steyn PS Mycotoxins, general view, chemistry and structure. 1995 Toxicol. Lett. pmid:8597152
Kuiper-Goodman T Mycotoxins: risk assessment and legislation. 1995 Toxicol. Lett. pmid:8597153
Clarke R et al. High content analysis: a sensitive tool to detect and quantify the cytotoxic, synergistic and antagonistic effects of chemical contaminants in foods. 2015 Toxicol. Lett. pmid:25623391
Chuturgoon AA et al. Fumonisin B₁ modulates expression of human cytochrome P450 1b1 in human hepatoma (Hepg2) cells by repressing Mir-27b. 2014 Toxicol. Lett. pmid:24614526
Fernández-Blanco C et al. An in vitro investigation on the cytotoxic and nuclear receptor transcriptional activity of the mycotoxins fumonisin B1 and beauvericin. 2016 Toxicol. Lett. pmid:27234500
Chuturgoon AA et al. Fumonisin B₁ inhibits apoptosis in HepG2 cells by inducing Birc-8/ILP-2. 2015 Toxicol. Lett. pmid:25800559
He Q et al. Fumonisin-induced tumor necrosis factor-alpha expression in a porcine kidney cell line is independent of sphingoid base accumulation induced by ceramide synthase inhibition. 2001 Toxicol. Appl. Pharmacol. pmid:11437650
Ramasamy S et al. Fumonisin B1 alters sphingolipid metabolism and disrupts the barrier function of endothelial cells in culture. 1995 Toxicol. Appl. Pharmacol. pmid:7645031
Constable PD et al. Ingestion of fumonisin B1-containing culture material decreases cardiac contractility and mechanical efficiency in swine. 2000 Toxicol. Appl. Pharmacol. pmid:10652243
Mobio TA et al. Epigenetic properties of fumonisin B(1): cell cycle arrest and DNA base modification in C6 glioma cells. 2000 Toxicol. Appl. Pharmacol. pmid:10739748
Suzuki CA et al. The effects of fumonisin B1 on several markers of nephrotoxicity in rats. 1995 Toxicol. Appl. Pharmacol. pmid:7645015
Gardner NM et al. Elevated nuclear sphingoid base-1-phosphates and decreased histone deacetylase activity after fumonisin B1 treatment in mouse embryonic fibroblasts. 2016 Toxicol. Appl. Pharmacol. pmid:26905748
Carlson DB et al. Fumonisin B1 promotes aflatoxin B1 and N-methyl-N'-nitro-nitrosoguanidine-initiated liver tumors in rainbow trout. 2001 Toxicol. Appl. Pharmacol. pmid:11264020
Kim MS et al. Fumonisin B(1) induces apoptosis in LLC-PK(1) renal epithelial cells via a sphinganine- and calmodulin-dependent pathway. 2001 Toxicol. Appl. Pharmacol. pmid:11601888