fumonisin b1

fumonisin b1 is a lipid of Sphingolipids (SP) class. Fumonisin b1 is associated with abnormalities such as Infection, Kidney Diseases, Liver diseases, DERMATITIS HERPETIFORMIS, FAMILIAL and Malnutrition. The involved functions are known as Gene Expression, Anabolism, Signal, Biosynthetic Pathways and Regulation. Fumonisin b1 often locates in Body tissue, Microsomes, microsomal membrane, Protoplasm and Mitochondria. The associated genes with fumonisin b1 are Genome, P4HTM gene, FATE1 gene, BCL2 gene and TMEM132D gene. The related lipids are dihydroceramide, ceramide 1-phosphate, Sphingolipids, Fatty Acids and Palmitates.

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Introduction

To understand associated biological information of fumonisin b1, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with fumonisin b1?

fumonisin b1 is suspected in Infection, Kidney Diseases, Liver diseases, DERMATITIS HERPETIFORMIS, FAMILIAL, Malnutrition, Celiac Disease and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with fumonisin b1

MeSH term MeSH ID Detail
Chemical and Drug Induced Liver Injury D056486 39 associated lipids
Pneumonia, Bacterial D018410 16 associated lipids
Adenoma, Liver Cell D018248 2 associated lipids
Neuroectodermal Tumors, Primitive, Peripheral D018241 3 associated lipids
Weight Gain D015430 101 associated lipids
Testicular Diseases D013733 15 associated lipids
Swine Diseases D013553 16 associated lipids
Stomatitis D013280 14 associated lipids
Stomach Ulcer D013276 75 associated lipids
Spinal Cord Injuries D013119 34 associated lipids
Per page 10 20 50 100 | Total 54

PubChem Associated disorders and diseases

What pathways are associated with fumonisin b1

Lipid pathways are not clear in current pathway databases. We organized associated pathways with fumonisin b1 through full-text articles, including metabolic pathways or pathways of biological mechanisms.

Related references are published most in these journals:

Pathway name Related literatures
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PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with fumonisin b1?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with fumonisin b1?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with fumonisin b1?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with fumonisin b1?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with fumonisin b1?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with fumonisin b1

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Per page 10 20 50 100 | Total 1278
Authors Title Published Journal PubMed Link
Meivar-Levy I and Futerman AH Up-regulation of neutral glycosphingolipid synthesis upon long term inhibition of ceramide synthesis by fumonisin B1. 1999 J. Biol. Chem. pmid:9988695
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Riley RT et al. Alteration in sphingolipid metabolism: bioassays for fumonisin- and ISP-I-like activity in tissues, cells and other matrices. 1999 Nat. Toxins pmid:11122537
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Warfield CY and Gilchrist DG Influence of kernel age on fumonisin B1 production in maize by Fusarium moniliforme. 1999 Appl. Environ. Microbiol. pmid:10388675
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Abbas HK et al. Mycotoxin production by Fusarium proliferatum isolates from rice with Fusarium sheath rot disease. 1999 Mycopathologia pmid:10967968
Tolleson WH et al. Fumonisin B1 induces apoptosis in cultured human keratinocytes through sphinganine accumulation and ceramide depletion. 1999 Int. J. Oncol. pmid:10200332
Ginis I et al. TNF-alpha pretreatment prevents subsequent activation of cultured brain cells with TNF-alpha and hypoxia via ceramide. 1999 Am. J. Physiol. pmid:10329967
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Van Overmeire I et al. Synthesis and biological evaluation of ceramide analogues with substituted aromatic rings or an allylic fluoride in the sphingoid moiety. 2000 J. Med. Chem. pmid:11063615
Asai T et al. Fumonisin B1-induced cell death in arabidopsis protoplasts requires jasmonate-, ethylene-, and salicylate-dependent signaling pathways. 2000 Plant Cell pmid:11041879
Seegers JC et al. Fumonisin B1 influenced the effects of arachidonic acid, prostaglandins E2 and A2 on cell cycle progression, apoptosis induction, tyrosine- and CDC2-kinase activity in oesophageal cancer cells. 2000 Prostaglandins Leukot. Essent. Fatty Acids pmid:10780872
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DiPietrantonio AM et al. Specific processing of poly(ADP-ribose) polymerase, accompanied by activation of caspase-3 and elevation/reduction of ceramide/hydrogen peroxide levels, during induction of apoptosis in host HL-60 cells infected by the human granulocytic ehrlichiosis (HGE) agent. 2000 IUBMB Life pmid:10772341
Takasaki M et al. Cancer chemopreventive activity of euglobal-G1 from leaves of Eucalyptus grandis. 2000 Cancer Lett. pmid:10814880
Moon WS et al. Early ultrastructural changes of apoptosis induced by fumonisin B1 in rat liver. 2000 Yonsei Med. J. pmid:10817019
Zomborszky-Kovács M et al. Preliminary communication: examination of the harmful effect to fetuses of fumonisin B(1) in pregnant sows. 2000 Teratog., Carcinog. Mutagen. pmid:10992276
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Preis RA and Vargas EA A method for determining fumonisin B1 in corn using immunoaffinity column clean-up and thin layer chromatography/densitometry. 2000 Food Addit Contam pmid:10932789
Sharma RP et al. Fumonisin hepatotoxicity is reduced in mice carrying the human tumour necrosis factor alpha transgene. 2000 Arch. Toxicol. pmid:10959799
Dombrink-Kurtzman MA et al. Activation of rat splenic macrophage and lymphocyte functions by fumonisin B1. 2000 Immunopharmacology pmid:10996037
Gutema T et al. Occurrence of fumonisins and moniliformin in corn and corn-based food products of U.S. origin. 2000 J. Food Prot. pmid:11131899
Ramljak D et al. A potential mechanism for fumonisin B(1)-mediated hepatocarcinogenesis: cyclin D1 stabilization associated with activation of Akt and inhibition of GSK-3beta activity. 2000 Carcinogenesis pmid:10910956
Wang H et al. The fumonisin B1 content in corn from North China, a high-risk area of esophageal cancer. 2000 J. Environ. Pathol. Toxicol. Oncol. pmid:10905519
Nagy B et al. Fumonisin B1 does not prevent apoptosis in A431 human epidermoid carcinoma cells after photosensitization with a silicon phthalocyanine. 2000 J. Photochem. Photobiol. B, Biol. pmid:11154079
Zomborszky MK et al. Experiment to determine limits of tolerance for fumonisin B1 in weaned piglets. 2000 J. Vet. Med. B Infect. Dis. Vet. Public Health pmid:10861196
da Silva JB et al. Mycoflora and occurrence of aflatoxin B(1) and fumonisin B(1) during storage of Brazilian sorghum. 2000 J. Agric. Food Chem. pmid:10995362