fumonisin b1 is a lipid of Sphingolipids (SP) class. Fumonisin b1 is associated with abnormalities such as Infection, Kidney Diseases, Liver diseases, DERMATITIS HERPETIFORMIS, FAMILIAL and Malnutrition. The involved functions are known as Gene Expression, Anabolism, Signal, Biosynthetic Pathways and Regulation. Fumonisin b1 often locates in Body tissue, Microsomes, microsomal membrane, Protoplasm and Mitochondria. The associated genes with fumonisin b1 are Genome, P4HTM gene, FATE1 gene, BCL2 gene and TMEM132D gene. The related lipids are dihydroceramide, ceramide 1-phosphate, Sphingolipids, Fatty Acids and Palmitates.
To understand associated biological information of fumonisin b1, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
fumonisin b1 is suspected in Infection, Kidney Diseases, Liver diseases, DERMATITIS HERPETIFORMIS, FAMILIAL, Malnutrition, Celiac Disease and other diseases in descending order of the highest number of associated sentences.
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We collected disease MeSH terms mapped to the references associated with fumonisin b1
Lipid pathways are not clear in current pathway databases. We organized associated pathways with fumonisin b1 through full-text articles, including metabolic pathways or pathways of biological mechanisms.
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Associated locations are in red color. Not associated locations are in black.
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There are no associated biomedical information in the current reference collection.
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Tolleson WH et al. | Fumonisin B1 induces apoptosis in cultured human keratinocytes through sphinganine accumulation and ceramide depletion. | 1999 | Int. J. Oncol. | pmid:10200332 |
Gamen S et al. | Caspases are the main executioners of Fas-mediated apoptosis, irrespective of the ceramide signalling pathway. | 1998 | Cell Death Differ. | pmid:10200470 |
Abeywickrama K et al. | Effects of Fusarium moniliforme culture extracts and fumonisin B1 on DNA, RNA and protein synthesis by baby hamster kidney cells. | 1998 | Mycopathologia | pmid:10205886 |
Charoenpornsook K et al. | The effects of four mycotoxins on the mitogen stimulated proliferation of bovine peripheral blood mononuclear cells in vitro. | 1998 | Mycopathologia | pmid:10205890 |
Zhang Y et al. | The mycotoxin fumonisin B1 transcriptionally activates the p21 promoter through a cis-acting element containing two Sp1 binding sites. | 1999 | J. Biol. Chem. | pmid:10212208 |
Ginis I et al. | TNF-alpha pretreatment prevents subsequent activation of cultured brain cells with TNF-alpha and hypoxia via ceramide. | 1999 | Am. J. Physiol. | pmid:10329967 |
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Lemmer ER et al. | Histopathology and gene expression changes in rat liver during feeding of fumonisin B1, a carcinogenic mycotoxin produced by Fusarium moniliforme. | 1999 | Carcinogenesis | pmid:10334199 |
Baker DC and Rottinghaus GE | Chronic experimental fumonisin intoxication of calves. | 1999 | J. Vet. Diagn. Invest. | pmid:10353364 |
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Blackwell BA et al. | Oxidative deamination of hydrolyzed fumonisin B(1) (AP(1)) by cultures of Exophiala spinifera. | 1999 | Nat. Toxins | pmid:10441035 |
Spinedi A et al. | Ceramide accumulation precedes caspase-dependent apoptosis in CHP-100 neuroepithelioma cells exposed to the protein phosphatase inhibitor okadaic acid. | 1999 | Cell Death Differ. | pmid:10453072 |
Williamson LC et al. | Neuronal sensitivity to tetanus toxin requires gangliosides. | 1999 | J. Biol. Chem. | pmid:10455200 |
Pinelli E et al. | Activation of mitogen-activated protein kinase by fumonisin B(1) stimulates cPLA(2) phosphorylation, the arachidonic acid cascade and cAMP production. | 1999 | Carcinogenesis | pmid:10469611 |
Lefrancois S et al. | Role of sphingolipids in the transport of prosaposin to the lysosomes. | 1999 | J. Lipid Res. | pmid:10484606 |
Velázquez C et al. | Linking extraction and purification of maize samples for fumonisin analysis. | 1999 | Food Addit Contam | pmid:10492705 |
Ciacci-Zanella JR and Jones C | Fumonisin B1, a mycotoxin contaminant of cereal grains, and inducer of apoptosis via the tumour necrosis factor pathway and caspase activation. | 1999 | Food Chem. Toxicol. | pmid:10496371 |
Voss KA et al. | Fusaric acid and modification of the subchronic toxicity to rats of fumonisins in F. moniliforme culture material. | 1999 | Food Chem. Toxicol. | pmid:10506009 |
Li YC et al. | Effects of fumonisin B1 on selected immune responses in broiler chicks. | 1999 | Poult. Sci. | pmid:10515357 |
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Dantzer WR et al. | Excretion of (14)C-fumonisin B(1), (14)C-hydrolyzed fumonisin B(1), and (14)C-fumonisin B(1)-fructose in rats. | 1999 | J. Agric. Food Chem. | pmid:10552804 |
Castellá G et al. | Surveillance of fumonisins in maize-based feeds and cereals from spain. | 1999 | J. Agric. Food Chem. | pmid:10552876 |
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Yu FY and Chu FS | Production and characterization of a monoclonal anti-anti-idiotype antibody against fumonisin B(1). | 1999 | J. Agric. Food Chem. | pmid:10552895 |
Kubena LF et al. | Effects of long-term feeding of diets containing moniliformin, supplied by Fusarium fujikuroi culture material, and fumonisin, supplied by Fusarium moniliforme culture material, to laying hens. | 1999 | Poult. Sci. | pmid:10560820 |
Riley RT and Plattner RD | Fermentation, partial purification, and use of serine palmitoyltransferase inhibitors from Isaria (= Cordyceps) sinclairii. | 2000 | Meth. Enzymol. | pmid:10563339 |
Pujol R et al. | Fate of fumonisin B(1) in corn kernel steeping water containing SO(2). | 1999 | J. Agric. Food Chem. | pmid:10563885 |
Dombrink-Kurtzman MA and Dvorak TJ | Fumonisin content in masa and tortillas from Mexico. | 1999 | J. Agric. Food Chem. | pmid:10563942 |
Fredman P et al. | The glycosphingolipid sulfatide in the islets of Langerhans in rat pancreas is processed through recycling: possible involvement in insulin trafficking. | 2000 | Glycobiology | pmid:10570222 |
Yates IE et al. | Trichoderma viride suppresses fumonisin B1 production by Fusarium moniliforme. | 1999 | J. Food Prot. | pmid:10571324 |
MarÃn S et al. | Two-dimensional profiles of fumonisin B1 production by Fusarium moniliforme and Fusarium proliferatum in relation to environmental factors and potential for modelling toxin formation in maize grain. | 1999 | Int. J. Food Microbiol. | pmid:10574091 |
Gelderblom WC et al. | Regulation of fatty acid biosynthesis as a possible mechanism for the mitoinhibitory effect of fumonisin B1 in primary rat hepatocytes. | 1999 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:10574646 |
Pelagalli A et al. | The mycotoxin fumonisin B1 inhibits integrin-mediated cell-matrix adhesion. | 1999 | Biochimie | pmid:10575354 |
Wang XZ et al. | Aberrant sphingolipid signaling is involved in the resistance of prostate cancer cell lines to chemotherapy. | 1999 | Cancer Res. | pmid:10582708 |
Abbas HK et al. | Fumonisin B1 from the fungus Fusarium moniliforme causes contact toxicity in plants: evidence from studies with biosynthetically labeled toxin. | 1999 | J Nat Toxins | pmid:10591043 |