fumonisin b1 is a lipid of Sphingolipids (SP) class. Fumonisin b1 is associated with abnormalities such as Infection, Kidney Diseases, Liver diseases, DERMATITIS HERPETIFORMIS, FAMILIAL and Malnutrition. The involved functions are known as Gene Expression, Anabolism, Signal, Biosynthetic Pathways and Regulation. Fumonisin b1 often locates in Body tissue, Microsomes, microsomal membrane, Protoplasm and Mitochondria. The associated genes with fumonisin b1 are Genome, P4HTM gene, FATE1 gene, BCL2 gene and TMEM132D gene. The related lipids are dihydroceramide, ceramide 1-phosphate, Sphingolipids, Fatty Acids and Palmitates.
To understand associated biological information of fumonisin b1, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
fumonisin b1 is suspected in Infection, Kidney Diseases, Liver diseases, DERMATITIS HERPETIFORMIS, FAMILIAL, Malnutrition, Celiac Disease and other diseases in descending order of the highest number of associated sentences.
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We collected disease MeSH terms mapped to the references associated with fumonisin b1
Lipid pathways are not clear in current pathway databases. We organized associated pathways with fumonisin b1 through full-text articles, including metabolic pathways or pathways of biological mechanisms.
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Associated locations are in red color. Not associated locations are in black.
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Function | Cross reference | Weighted score | Related literatures |
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Gene | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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Bhandari N et al. | Gender-related differences in subacute fumonisin B1 hepatotoxicity in BALB/c mice. | 2001 | Toxicology | pmid:11522378 |
Norred WP et al. | Instability of N-acetylated fumonisin B1 (FA1) and the impact on inhibition of ceramide synthase in rat liver slices. | 2001 | Food Chem. Toxicol. | pmid:11527566 |
Sewram V et al. | Assessing chronic exposure to fumonisin mycotoxins: the use of hair as a suitable noninvasive matrix. | 2001 | J Anal Toxicol | pmid:11550819 |
Torres AM et al. | Fusarium species (section Liseola) and its mycotoxins in maize harvested in northern Argentina. | 2001 | Food Addit Contam | pmid:11552751 |
Yang MS et al. | Sphingomyelinase but not ceramide induces nitric oxide synthase expression in rat brain microglia. | 2001 | Neurosci. Lett. | pmid:11567796 |
Kim MS et al. | Fumonisin B(1) induces apoptosis in LLC-PK(1) renal epithelial cells via a sphinganine- and calmodulin-dependent pathway. | 2001 | Toxicol. Appl. Pharmacol. | pmid:11601888 |
Johnson VJ and Sharma RP | Gender-dependent immunosuppression following subacute exposure to fumonisin B1. | 2001 | Int. Immunopharmacol. | pmid:11606033 |
Ueda N et al. | Role of ceramide synthase in oxidant injury to renal tubular epithelial cells. | 2001 | J. Am. Soc. Nephrol. | pmid:11675414 |
Ganassi S et al. | Effect of Fusarium, Paecilomyces and Trichoderma formulations against aphid Schizaphis graminum. | 2001 | Mycopathologia | pmid:11678587 |
Solfrizzo M et al. | In vitro and in vivo studies to assess the effectiveness of cholestyramine as a binding agent for fumonisins. | 2001 | Mycopathologia | pmid:11678589 |
Ghosh S et al. | Generation of ceramide in murine macrophages infected with Leishmania donovani alters macrophage signaling events and aids intracellular parasitic survival. | 2001 | Mol. Cell. Biochem. | pmid:11681721 |
Schorling S et al. | Lag1p and Lac1p are essential for the Acyl-CoA-dependent ceramide synthase reaction in Saccharomyces cerevisae. | 2001 | Mol. Biol. Cell | pmid:11694577 |
Abnet CC et al. | Sphingolipids as biomarkers of fumonisin exposure and risk of esophageal squamous cell carcinoma in china. | 2001 | Cancer Causes Control | pmid:11714110 |
Baron CL and Malhotra V | Role of diacylglycerol in PKD recruitment to the TGN and protein transport to the plasma membrane. | 2002 | Science | pmid:11729268 |
Galvano F et al. | DNA damage in human fibroblasts exposed to fumonisin B(1). | 2002 | Food Chem. Toxicol. | pmid:11731033 |
Visconti A et al. | Determination of fumonisins B1 and B2 in corn and corn flakes by liquid chromatography with immunoaffinity column cleanup: collaborative study. | 2001 Nov-Dec | J AOAC Int | pmid:11767152 |
Theumer MG et al. | Immunobiological effects of fumonisin B1 in experimental subchronic mycotoxicoses in rats. | 2002 | Clin. Diagn. Lab. Immunol. | pmid:11777845 |
Mahfoud R et al. | pH-dependent interaction of fumonisin B1 with cholesterol: physicochemical and molecular modeling studies at the air-water interface. | 2002 | J. Agric. Food Chem. | pmid:11782202 |
Kong JY and Rabkin SW | Palmitate-induced cardiac apoptosis is mediated through CPT-1 but not influenced by glucose and insulin. | 2002 | Am. J. Physiol. Heart Circ. Physiol. | pmid:11788422 |
Gamanya R and Sibanda L | Survey of Fusarium moniliforme (F. verticillioides) and production of fumonisin B1 in cereal grains and oilseeds in Zimbabwe. | 2001 | Int. J. Food Microbiol. | pmid:11789932 |
Chalfant CE et al. | De novo ceramide regulates the alternative splicing of caspase 9 and Bcl-x in A549 lung adenocarcinoma cells. Dependence on protein phosphatase-1. | 2002 | J. Biol. Chem. | pmid:11801602 |
Bakan B et al. | Fungal growth and fusarium mycotoxin content in isogenic traditional maize and genetically modified maize grown in France and Spain. | 2002 | J. Agric. Food Chem. | pmid:11829636 |
Gelderblom WC et al. | Interaction of fumonisin B(1) and aflatoxin B(1) in a short-term carcinogenesis model in rat liver. | 2002 | Toxicology | pmid:11836022 |
Harvey B et al. | Toxicity of fumonisin from Fusarium verticillioides culture material and moniliformin from Fusarium fujikuroi culture material when fed singly and in combination to growing barrows. | 2002 | J. Food Prot. | pmid:11848570 |
Toxicology and carcinogenesis studies of fumonisin B1 (cas no. 116355-83-0) in F344/N rats and B6C3F1 mice (feed studies). | 2001 | Natl Toxicol Program Tech Rep Ser | pmid:11852482 | |
Poling SM et al. | N-(1-deoxy-D-fructos-1-yl) fumonisin B(1), the initial reaction product of fumonisin B(1) and D-glucose. | 2002 | J. Agric. Food Chem. | pmid:11853524 |
Lefrancois S et al. | The lysosomal transport of prosaposin requires the conditional interaction of its highly conserved d domain with sphingomyelin. | 2002 | J. Biol. Chem. | pmid:11856752 |
Brandwagt BF et al. | Overexpression of the tomato Asc-1 gene mediates high insensitivity to AAL toxins and fumonisin B1 in tomato hairy roots and confers resistance to Alternaria alternata f. sp. lycopersici in Nicotiana umbratica plants. | 2002 | Mol. Plant Microbe Interact. | pmid:11858172 |
Wang Z et al. | [Characteristics of producing-fumonisin and dimorphic fungus of fusarium moniliforme]. | 2000 | Zhonghua Yu Fang Yi Xue Za Zhi | pmid:11860899 |
Rumora L et al. | Cytotoxic and genotoxic effects of fumonisin B1 on rabbit kidney RK13 cell line. | 2002 | Arch. Toxicol. | pmid:11875625 |
Bhandari N et al. | Temporal expression of fumonisin B(1)-induced tumor necrosis factor-alpha and interferon gamma in mice. | 2002 | Comp. Biochem. Physiol. C Toxicol. Pharmacol. | pmid:11879779 |
Bhandari N et al. | Modulation of selected cell signaling genes in mouse liver by fumonisin B1. | 2002 | Chem. Biol. Interact. | pmid:11879819 |
Bhandari N and Sharma RP | Fumonisin B(1)-induced alterations in cytokine expression and apoptosis signaling genes in mouse liver and kidney after an acute exposure. | 2002 | Toxicology | pmid:11882348 |
Itakura A et al. | Ceramide and sphingosine rapidly induce apoptosis of murine mast cells supported by interleukin-3 and stem cell factor. | 2002 | Exp. Hematol. | pmid:11882365 |
Broomhead JN et al. | Chronic effects of fumonisin B1 in broilers and turkeys fed dietary treatments to market age. | 2002 | Poult. Sci. | pmid:11885900 |
Ferrante MC et al. | Effect of fumonisin B1 on structure and function of macrophage plasma membrane. | 2002 | Toxicol. Lett. | pmid:11888701 |
Kozutsumi Y et al. | [Sphingolipid probe]. | 2002 | Tanpakushitsu Kakusan Koso | pmid:11915351 |
Guo Y et al. | [Studies on immunoassay for detecting fumonisin B1]. | 1999 | Wei Sheng Yan Jiu | pmid:11938987 |
Smith GW et al. | Cardiovascular changes associated with intravenous administration of fumonisin B1 in horses. | 2002 | Am. J. Vet. Res. | pmid:11939316 |
Min JK et al. | Simultaneous quantitative analysis of sphingoid base 1-phosphates in biological samples by o-phthalaldehyde precolumn derivatization after dephosphorylation with alkaline phosphatase. | 2002 | Anal. Biochem. | pmid:11950216 |
Galvano F et al. | DNA damage in astrocytes exposed to fumonisin B1. | 2002 | Neurochem. Res. | pmid:11958538 |
Ehrlich V et al. | Fumonisin B(1) is genotoxic in human derived hepatoma (HepG2) cells. | 2002 | Mutagenesis | pmid:11971998 |
Seefelder W et al. | Analysis of fumonisin B(1) in Fusarium proliferatum-infected asparagus spears and garlic bulbs from Germany by liquid chromatography-electrospray ionization mass spectrometry. | 2002 | J. Agric. Food Chem. | pmid:11982398 |
Bird CB et al. | Determination of total fumonisins in corn by competitive direct enzyme-linked immunosorbent assay: collaborative study. | 2002 Mar-Apr | J AOAC Int | pmid:11990026 |
Banczerowski-Pelyhe I et al. | In vivo and in vitro electrophysiological monitoring of rat neocortical activity after dietary fumonisin exposure. | 2002 | Mycopathologia | pmid:11998878 |
Liu BH et al. | The effects of mycotoxins, fumonisin B1 and aflatoxin B1, on primary swine alveolar macrophages. | 2002 | Toxicol. Appl. Pharmacol. | pmid:12009859 |
Enongene EN et al. | Persistence and reversibility of the elevation in free sphingoid bases induced by fumonisin inhibition of ceramide synthase. | 2002 | Toxicol. Sci. | pmid:12011476 |
Kim EK et al. | Survey for fumonisin B1 in Korean corn-based food products. | 2002 | Food Addit Contam | pmid:12028644 |
Broggi LE et al. | Distribution of fumonisins in dry-milled corn fractions in Argentina. | 2002 | Food Addit Contam | pmid:12028645 |
Kim EK et al. | Extraction of fumonisins B1 and B2 from white rice flour and their stability in white rice flour, cornstarch, cornmeal, and glucose. | 2002 | J. Agric. Food Chem. | pmid:12033838 |
Akao Y et al. | Ceramide accumulation is independent of camptothecin-induced apoptosis in prostate cancer LNCaP cells. | 2002 | Biochem. Biophys. Res. Commun. | pmid:12051721 |
Almeida AP et al. | Mycoflora and fumonisin contamination in Brazilian corn from sowing to harvest. | 2002 | J. Agric. Food Chem. | pmid:12059175 |
Trigo-Stockli DM et al. | Fumonisin B1 levels in 1995 and 1996 Kansas corn. | 2002 | Bull Environ Contam Toxicol | pmid:12068939 |
Zomborszky-Kovács M et al. | Effects of prolonged exposure to low-dose fumonisin B1 in pigs. | 2002 | J. Vet. Med. B Infect. Dis. Vet. Public Health | pmid:12069274 |
He Q et al. | Pharmacological antagonism of fumonisin B1 cytotoxicity in porcine renal epithelial cells (LLC-PK1): a model for reducing fumonisin-induced nephrotoxicity in vivo. | 2002 | Pharmacol. Toxicol. | pmid:12076308 |
Voss KA et al. | Carcinogenicity and mechanism of action of fumonisin B1: a mycotoxin produced by Fusarium moniliforme (= F. verticillioides). | 2002 | Cancer Detect. Prev. | pmid:12088196 |
Venkataraman K et al. | Upstream of growth and differentiation factor 1 (uog1), a mammalian homolog of the yeast longevity assurance gene 1 (LAG1), regulates N-stearoyl-sphinganine (C18-(dihydro)ceramide) synthesis in a fumonisin B1-independent manner in mammalian cells. | 2002 | J. Biol. Chem. | pmid:12105227 |
Trucksess MW et al. | Occurrence of aflatoxins and fumonisins in Incaparina from Guatemala. | 2002 | Food Addit Contam | pmid:12113662 |
Shephard GS et al. | Fumonisin B(1) in maize harvested in Iran during 1999. | 2002 | Food Addit Contam | pmid:12113663 |
Lu Y et al. | Characterization of fumonisin B(1)-glucose reaction kinetics and products. | 2002 | J. Agric. Food Chem. | pmid:12137505 |
Myburg RB et al. | Cytotoxicity of fumonisin B1, diethylnitrosamine, and catechol on the SNO esophageal cancer cell line. | 2002 | Environ. Health Perspect. | pmid:12153764 |
Caloni F et al. | Evaluation of Fumonisin B(1) and its metabolites absorption and toxicity on intestinal cells line Caco-2. | 2002 | Toxicon | pmid:12165322 |
He Q et al. | Fumonisin B(1) alters sphingolipid metabolism and tumor necrosis factor alpha expression in heart and lung of mice. | 2002 | Life Sci. | pmid:12175895 |
Abbas HK et al. | Aflatoxin and fumonisin contamination of commercial corn (Zea mays) hybrids in Mississippi. | 2002 | J. Agric. Food Chem. | pmid:12188638 |
Gueguen G et al. | A lysophosphatidic acid analogue is revealed as a potent inhibitor of phosphatidylcholine synthesis, inducing apoptosis. | 2002 | Biochem. J. | pmid:12197836 |
Jenkins GM et al. | Acute activation of de novo sphingolipid biosynthesis upon heat shock causes an accumulation of ceramide and subsequent dephosphorylation of SR proteins. | 2002 | J. Biol. Chem. | pmid:12200446 |
Wispriyono B et al. | A role for the de novo sphingolipids in apoptosis of photosensitized cells. | 2002 | Exp. Cell Res. | pmid:12213223 |
Cortez-Rocha MO et al. | Effect of extrusion processing on fumonisin B(1) and hydrolyzed fumonisin B(1) in contaminated alkali-cooked corn. | 2002 | Bull Environ Contam Toxicol | pmid:12232716 |
Le Stunff H et al. | Sphingosine-1-phosphate phosphohydrolase in regulation of sphingolipid metabolism and apoptosis. | 2002 | J. Cell Biol. | pmid:12235122 |
Fotso J et al. | Production of beauvericin, moniliformin, fusaproliferin, and fumonisins b(1), b(2), and b(3) by fifteen ex-type strains of fusarium species. | 2002 | Appl. Environ. Microbiol. | pmid:12324376 |
Dresden-Osborne C and Noblet GP | Fumonisin B1 affects viability and alters nitric oxide production of a murine macrophage cell line. | 2002 | Int. Immunopharmacol. | pmid:12349946 |
Sadler TW et al. | Prevention of fumonisin B1-induced neural tube defects by folic acid. | 2002 | Teratology | pmid:12353213 |
Bhandari N et al. | Fumonisin B1-induced localized activation of cytokine network in mouse liver. | 2002 | Food Chem. Toxicol. | pmid:12387313 |
Desjardins AE et al. | FUM1--a gene required for fumonisin biosynthesis but not for maize ear rot and ear infection by Gibberella moniliformis in field tests. | 2002 | Mol. Plant Microbe Interact. | pmid:12423021 |
Hinkovska-Galcheva V et al. | Enhanced phagocytosis through inhibition of de novo ceramide synthesis. | 2003 | J. Biol. Chem. | pmid:12424251 |
Gelderblom WC et al. | Lipids and delta6-desaturase activity alterations in rat liver microsomal membranes induced by fumonisin B1. | 2002 | Lipids | pmid:12458622 |
Ho JA and Durst RA | Detection of fumonisin B1: comparison of flow-injection liposome immunoanalysis with high-performance liquid chromatography. | 2003 | Anal. Biochem. | pmid:12479829 |
Leung LW et al. | Inhibitors of glycosphingolipid biosynthesis reduce transepithelial electrical resistance in MDCK I and FRT cells. | 2003 | Am. J. Physiol., Cell Physiol. | pmid:12490435 |
Howard PC et al. | Comparison of the toxicity of several fumonisin derivatives in a 28-day feeding study with female B6C3F(1) mice. | 2002 | Toxicol. Appl. Pharmacol. | pmid:12498732 |
Banczerowski-Pelyhe I et al. | Nerve conduction velocity and spinal reflexes may change in rats after fumonisin B1 exposure. | 2002 | Acta. Biol. Hung. | pmid:12501928 |
Mobio TA et al. | Comparative study of the toxic effects of fumonisin B1 in rat C6 glioma cells and p53-null mouse embryo fibroblasts. | 2003 | Toxicology | pmid:12504343 |
Williams LD et al. | Leaching and binding of fumonisins in soil microcosms. | 2003 | J. Agric. Food Chem. | pmid:12537442 |
Litvak DA et al. | Modulators of ceramide metabolism sensitize colorectal cancer cells to chemotherapy: a novel treatment strategy. | 2003 | J. Gastrointest. Surg. | pmid:12559195 |
Zhao H et al. | Anoxia and reoxygenation of human endothelial cells decrease ceramide glucosyltransferase expression and activates caspases. | 2003 | FASEB J. | pmid:12586734 |
Theumer MG et al. | Immunobiological effects of AFB1 and AFB1-FB1 mixture in experimental subchronic mycotoxicoses in rats. | 2003 | Toxicology | pmid:12604180 |
Maedler K et al. | Monounsaturated fatty acids prevent the deleterious effects of palmitate and high glucose on human pancreatic beta-cell turnover and function. | 2003 | Diabetes | pmid:12606514 |
Kim EK et al. | Hidden fumonisin in corn flakes. | 2003 | Food Addit Contam | pmid:12623665 |
Sharma RP et al. | Deletion of IFN-gamma reduces fumonisin-induced hepatotoxicity in mice via alterations in inflammatory cytokines and apoptotic factors. | 2003 | J. Interferon Cytokine Res. | pmid:12639295 |
Uchida Y et al. | De novo ceramide synthesis participates in the ultraviolet B irradiation-induced apoptosis in undifferentiated cultured human keratinocytes. | 2003 | J. Invest. Dermatol. | pmid:12648232 |
Camargos SM et al. | Accumulation of fumonisins B1 and B2 in freshly harvested Brazilian commercial maize at three locations during two nonconsecutive seasons. | 2002 | Mycopathologia | pmid:12650599 |
Kritzinger Q et al. | Mycoflora and fumonisin mycotoxins associated with cowpea [Vigna unguiculata (L.) Walp] seeds. | 2003 | J. Agric. Food Chem. | pmid:12670154 |
Koyanagi S et al. | Elevation of de novo ceramide synthesis in tumor masses and the role of microsomal dihydroceramide synthase. | 2003 | Int. J. Cancer | pmid:12672022 |
Gopee NV and Sharma RP | Sphingoid bases and their phosphates: transient activation and delayed repression of protein kinase C isoforms and their possible involvement in fumonisin B1 cytotoxicity. | 2003 | Toxicology | pmid:12699912 |
Guo Y et al. | [Preparation and identification of anti-fumonisin B1 monoclonal antibody]. | 1999 | Wei Sheng Yan Jiu | pmid:12712702 |
Hering H et al. | Lipid rafts in the maintenance of synapses, dendritic spines, and surface AMPA receptor stability. | 2003 | J. Neurosci. | pmid:12716933 |
Wang H and Zhang X | [Recent progress in the study of common fusarium mycotoxins on apoptosis of cells]. | 2000 | Wei Sheng Yan Jiu | pmid:12725071 |
Johnson VJ et al. | Increased susceptibility of renal epithelial cells to TNFalpha-induced apoptosis following treatment with fumonisin B1. | 2003 | Chem. Biol. Interact. | pmid:12732456 |
Pepeljnjak S et al. | Screening toxicity study in young carp (Cyprinus carpio L.) on feed amended with fumonisin B1. | 2003 | Mycopathologia | pmid:12733635 |
Tornyos G et al. | Effect of dietary fumonisin B1 on certain immune parameters of weaned pigs. | 2003 | Acta Vet. Hung. | pmid:12737044 |
Okino N et al. | The reverse activity of human acid ceramidase. | 2003 | J. Biol. Chem. | pmid:12764132 |