fumonisin b1 is a lipid of Sphingolipids (SP) class. Fumonisin b1 is associated with abnormalities such as Infection, Kidney Diseases, Liver diseases, DERMATITIS HERPETIFORMIS, FAMILIAL and Malnutrition. The involved functions are known as Gene Expression, Anabolism, Signal, Biosynthetic Pathways and Regulation. Fumonisin b1 often locates in Body tissue, Microsomes, microsomal membrane, Protoplasm and Mitochondria. The associated genes with fumonisin b1 are Genome, P4HTM gene, FATE1 gene, BCL2 gene and TMEM132D gene. The related lipids are dihydroceramide, ceramide 1-phosphate, Sphingolipids, Fatty Acids and Palmitates.
To understand associated biological information of fumonisin b1, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
fumonisin b1 is suspected in Infection, Kidney Diseases, Liver diseases, DERMATITIS HERPETIFORMIS, FAMILIAL, Malnutrition, Celiac Disease and other diseases in descending order of the highest number of associated sentences.
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We collected disease MeSH terms mapped to the references associated with fumonisin b1
Lipid pathways are not clear in current pathway databases. We organized associated pathways with fumonisin b1 through full-text articles, including metabolic pathways or pathways of biological mechanisms.
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Associated locations are in red color. Not associated locations are in black.
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Gene | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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Rumora L et al. | Cytotoxic and genotoxic effects of fumonisin B1 on rabbit kidney RK13 cell line. | 2002 | Arch. Toxicol. | pmid:11875625 |
Loiseau N et al. | New insights into the organ-specific adverse effects of fumonisin B1: comparison between lung and liver. | 2015 | Arch. Toxicol. | pmid:25155190 |
Wentzel JF et al. | Evaluation of the cytotoxic properties, gene expression profiles and secondary signalling responses of cultured cells exposed to fumonisin B1, deoxynivalenol and zearalenone mycotoxins. | 2017 | Arch. Toxicol. | pmid:27757495 |
Abado-Becognee K et al. | Cytotoxicity of fumonisin B1: implication of lipid peroxidation and inhibition of protein and DNA syntheses. | 1998 | Arch. Toxicol. | pmid:9587019 |
Klarić MS et al. | Cytotoxicity and apoptosis induced by fumonisin B(1), beauvericin and ochratoxin A in porcine kidney PK15 cells: effects of individual and combined treatment. | 2008 | Arch. Toxicol. | pmid:17879085 |
Sharma RP et al. | Fumonisin hepatotoxicity is reduced in mice carrying the human tumour necrosis factor alpha transgene. | 2000 | Arch. Toxicol. | pmid:10959799 |
Yin S et al. | Fumonisin B1 induces autophagic cell death via activation of ERN1-MAPK8/9/10 pathway in monkey kidney MARC-145 cells. | 2016 | Arch. Toxicol. | pmid:25925693 |
Dahdouh F et al. | Nickel-induced cell death and survival pathways in cultured renal proximal tubule cells: roles of reactive oxygen species, ceramide and ABCB1. | 2014 | Arch. Toxicol. | pmid:24448832 |
Mobio TA et al. | Prevention by vitamin E of DNA fragmentation and apoptosis induced by fumonisin B1 in C6 glioma cells. | 2000 | Arch. Toxicol. | pmid:10839479 |
Domijan AM | Fumonisin B(1): a neurotoxic mycotoxin. | 2012 | Arh Hig Rada Toksikol | pmid:23334049 |
Cvetnić Z et al. | Toxigenic potential of Fusarium species isolated from non-harvested maize. | 2005 | Arh Hig Rada Toksikol | pmid:16180614 |
Kovacić S et al. | Fumonisin B1 neurotoxicity in young carp (Cyprinus carpio L.). | 2009 | Arh Hig Rada Toksikol | pmid:20061242 |
Worgall TS et al. | Ceramide synthesis correlates with the posttranscriptional regulation of the sterol-regulatory element-binding protein. | 2004 | Arterioscler. Thromb. Vasc. Biol. | pmid:15132973 |
Alizadeh AM et al. | Fumonisin B1 contamination of cereals and risk of esophageal cancer in a high risk area in northeastern Iran. | 2012 | Asian Pac. J. Cancer Prev. | pmid:22938431 |
Christley RM et al. | Leukoencephalomalacia in horses. | 1993 | Aust. Vet. J. | pmid:8216085 |
Sousa FC et al. | Effect of fumonisin-containing diet on the myenteric plexus of the jejunum in rats. | 2014 | Auton Neurosci | pmid:25183308 |
Ledoux DR et al. | Individual and combined effects of the Fusarium mycotoxins fumonisin B1 and moniliformin in broiler chicks. | 2003 Oct-Dec | Avian Dis. | pmid:14708984 |
Espada Y et al. | Fumonisin mycotoxicosis in broilers: plasma proteins and coagulation modifications. | 1997 Jan-Mar | Avian Dis. | pmid:9087322 |
Brown TP et al. | Fumonisin mycotoxicosis in broilers: performance and pathology. | 1992 Apr-Jun | Avian Dis. | pmid:1627116 |
Deshmukh S et al. | Individual and combined effects of Fusarium moniliforme culture material, containing known levels of fumonisin B1, and Salmonella gallinarum infection on liver of Japanese quail. | 2005 | Avian Dis. | pmid:16405006 |