fumonisin b1 is a lipid of Sphingolipids (SP) class. Fumonisin b1 is associated with abnormalities such as Infection, Kidney Diseases, Liver diseases, DERMATITIS HERPETIFORMIS, FAMILIAL and Malnutrition. The involved functions are known as Gene Expression, Anabolism, Signal, Biosynthetic Pathways and Regulation. Fumonisin b1 often locates in Body tissue, Microsomes, microsomal membrane, Protoplasm and Mitochondria. The associated genes with fumonisin b1 are Genome, P4HTM gene, FATE1 gene, BCL2 gene and TMEM132D gene. The related lipids are dihydroceramide, ceramide 1-phosphate, Sphingolipids, Fatty Acids and Palmitates.
To understand associated biological information of fumonisin b1, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
fumonisin b1 is suspected in Infection, Kidney Diseases, Liver diseases, DERMATITIS HERPETIFORMIS, FAMILIAL, Malnutrition, Celiac Disease and other diseases in descending order of the highest number of associated sentences.
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We collected disease MeSH terms mapped to the references associated with fumonisin b1
Lipid pathways are not clear in current pathway databases. We organized associated pathways with fumonisin b1 through full-text articles, including metabolic pathways or pathways of biological mechanisms.
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Associated locations are in red color. Not associated locations are in black.
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Gene | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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Lenz HD et al. | ATG7 contributes to plant basal immunity towards fungal infection. | 2011 | Plant Signal Behav | pmid:21617379 |
Qin X et al. | Sphingosine kinase AtSPHK1 functions in fumonisin B1-triggered cell death in Arabidopsis. | 2017 | Plant Physiol. Biochem. | pmid:28846870 |
Luttgeharm KD et al. | Overexpression of Arabidopsis Ceramide Synthases Differentially Affects Growth, Sphingolipid Metabolism, Programmed Cell Death, and Mycotoxin Resistance. | 2015 | Plant Physiol. | pmid:26276842 |
Feng H et al. | Functional characterization of the Arabidopsis eukaryotic translation initiation factor 5A-2 that plays a crucial role in plant growth and development by regulating cell division, cell growth, and cell death. | 2007 | Plant Physiol. | pmid:17513484 |
Zhao Y et al. | Classic myrosinase-dependent degradation of indole glucosinolate attenuates fumonisin B1-induced programmed cell death in Arabidopsis. | 2015 | Plant J. | pmid:25645692 |
Stone JM et al. | Arabidopsis AtSPL14, a plant-specific SBP-domain transcription factor, participates in plant development and sensitivity to fumonisin B1. | 2005 | Plant J. | pmid:15703061 |
Bindschedler LV et al. | Peroxidase-dependent apoplastic oxidative burst in Arabidopsis required for pathogen resistance. | 2006 | Plant J. | pmid:16889645 |
Watanabe N and Lam E | Arabidopsis Bax inhibitor-1 functions as an attenuator of biotic and abiotic types of cell death. | 2006 | Plant J. | pmid:16507080 |
Aubert A et al. | Sphingolipids involvement in plant endomembrane differentiation: the BY2 case. | 2011 | Plant J. | pmid:21205030 |
Lin SS et al. | RING1 E3 ligase localizes to plasma membrane lipid rafts to trigger FB1-induced programmed cell death in Arabidopsis. | 2008 | Plant J. | pmid:18643987 |
Lenz HD et al. | Autophagy differentially controls plant basal immunity to biotrophic and necrotrophic pathogens. | 2011 | Plant J. | pmid:21332848 |
Basnayake BM et al. | Arabidopsis DAL1 and DAL2, two RING finger proteins homologous to Drosophila DIAP1, are involved in regulation of programmed cell death. | 2011 | Plant Cell Rep. | pmid:20972793 |
Markham JE et al. | Sphingolipids containing very-long-chain fatty acids define a secretory pathway for specific polar plasma membrane protein targeting in Arabidopsis. | 2011 | Plant Cell | pmid:21666002 |
Chivasa S et al. | Extracellular ATP functions as an endogenous external metabolite regulating plant cell viability. | 2005 | Plant Cell | pmid:16199612 |
Asai T et al. | Fumonisin B1-induced cell death in arabidopsis protoplasts requires jasmonate-, ethylene-, and salicylate-dependent signaling pathways. | 2000 | Plant Cell | pmid:11041879 |
Kimberlin AN et al. | Arabidopsis 56-amino acid serine palmitoyltransferase-interacting proteins stimulate sphingolipid synthesis, are essential, and affect mycotoxin sensitivity. | 2013 | Plant Cell | pmid:24214397 |
Stone JM et al. | Simulation of fungal-mediated cell death by fumonisin B1 and selection of fumonisin B1-resistant (fbr) Arabidopsis mutants. | 2000 | Plant Cell | pmid:11041878 |
Arias SL et al. | Toxin distribution and sphingoid base imbalances in Fusarium verticillioides-infected and fumonisin B1-watered maize seedlings. | 2016 | Phytochemistry | pmid:26903312 |
Abbas HK et al. | Biological activities of synthetic analogues of Alternaria alternata toxin (AAL-toxin) and fumonisin in plant and mammalian cell cultures. | 1995 | Phytochemistry | pmid:8590636 |
Desjardins AE et al. | Identification and heritability of fumonisin insensitivity in Zea mays. | 2005 | Phytochemistry | pmid:16198380 |