fumonisin b1 is a lipid of Sphingolipids (SP) class. Fumonisin b1 is associated with abnormalities such as Infection, Kidney Diseases, Liver diseases, DERMATITIS HERPETIFORMIS, FAMILIAL and Malnutrition. The involved functions are known as Gene Expression, Anabolism, Signal, Biosynthetic Pathways and Regulation. Fumonisin b1 often locates in Body tissue, Microsomes, microsomal membrane, Protoplasm and Mitochondria. The associated genes with fumonisin b1 are Genome, P4HTM gene, FATE1 gene, BCL2 gene and TMEM132D gene. The related lipids are dihydroceramide, ceramide 1-phosphate, Sphingolipids, Fatty Acids and Palmitates.
To understand associated biological information of fumonisin b1, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
fumonisin b1 is suspected in Infection, Kidney Diseases, Liver diseases, DERMATITIS HERPETIFORMIS, FAMILIAL, Malnutrition, Celiac Disease and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
---|
We collected disease MeSH terms mapped to the references associated with fumonisin b1
Lipid pathways are not clear in current pathway databases. We organized associated pathways with fumonisin b1 through full-text articles, including metabolic pathways or pathways of biological mechanisms.
Pathway name | Related literatures |
---|
Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
---|
Function | Cross reference | Weighted score | Related literatures |
---|
Lipid concept | Cross reference | Weighted score | Related literatures |
---|
Gene | Cross reference | Weighted score | Related literatures |
---|
There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
---|---|---|---|---|
Tardieu D et al. | Determination of Fumonisin B1 in animal tissues with immunoaffinity purification. | 2008 | J. Chromatogr. B Analyt. Technol. Biomed. Life Sci. | pmid:18571484 |
Senyuva HZ et al. | Determination of fumonisins B1 and B2 in corn by liquid chromatography/mass spectrometry with immunoaffinity column cleanup: single-laboratory method validation. | 2008 May-Jun | J AOAC Int | pmid:18567306 |
Kim JE et al. | AMPK activator, AICAR, inhibits palmitate-induced apoptosis in osteoblast. | 2008 | Bone | pmid:18502715 |
Boudra H and Morgavi DP | Reduction in fusarium toxin levels in corn silage with low dry matter and storage time. | 2008 | J. Agric. Food Chem. | pmid:18498169 |
Sharma D et al. | Individual and combined effects of fumonisin b1 and moniliformin on clinicopathological and cell-mediated immune response in Japanese quail. | 2008 | Poult. Sci. | pmid:18492990 |
Marina Martins H et al. | Fumonisins and deoxynivalenol in corn-based food products in Portugal. | 2008 | Food Chem. Toxicol. | pmid:18486293 |
Odhav B et al. | Modulating effects of fumonisin B1 and ochratoxin A on leukocytes and messenger cytokines of the human immune system. | 2008 | Int. Immunopharmacol. | pmid:18442783 |
Kim H and Woloshuk CP | Role of AREA, a regulator of nitrogen metabolism, during colonization of maize kernels and fumonisin biosynthesis in Fusarium verticillioides. | 2008 | Fungal Genet. Biol. | pmid:18440841 |
Korfmacher WA et al. | Characterization of the mycotoxin fumonisin B1: comparison of thermospray, fast-atom bombardment and electrospray mass spectrometry. | 1991 | Rapid Commun. Mass Spectrom. | pmid:1841646 |
Gong YY et al. | Association between tortilla consumption and human urinary fumonisin B1 levels in a Mexican population. | 2008 | Cancer Epidemiol. Biomarkers Prev. | pmid:18349288 |
Blázquez C et al. | Cannabinoids inhibit glioma cell invasion by down-regulating matrix metalloproteinase-2 expression. | 2008 | Cancer Res. | pmid:18339876 |
Bullerman LB et al. | Reduction of fumonisin B1 in corn grits by single-screw extrusion. | 2008 | J. Agric. Food Chem. | pmid:18327966 |
Roscoe V et al. | Mycotoxins in breakfast cereals from the Canadian retail market: a 3-year survey. | 2008 | Food Addit Contam Part A Chem Anal Control Expo Risk Assess | pmid:18311625 |
Theumer MG et al. | The lipid-mediated hypothesis of fumonisin B1 toxicodynamics tested in model membranes. | 2008 | Colloids Surf B Biointerfaces | pmid:18296035 |
Liu YY et al. | A role for ceramide in driving cancer cell resistance to doxorubicin. | 2008 | FASEB J. | pmid:18245173 |
Yang LX et al. | [Association between murine double minute 2 expression and AngII and ceramide induced endothelial cells apoptosis]. | 2007 | Zhonghua Xin Xue Guan Bing Za Zhi | pmid:18206046 |
Stockmann-Juvala H et al. | Effects of fumonisin B(1) on the expression of cytokines and chemokines in human dendritic cells. | 2008 | Food Chem. Toxicol. | pmid:18194833 |
Choi YE and Shim WB | Functional characterization of Fusarium verticillioides CPP1, a gene encoding a putative protein phosphatase 2A catalytic subunit. | 2008 | Microbiology (Reading, Engl.) | pmid:18174151 |
Gnonlonfin GJ et al. | Mycoflora and natural occurrence of aflatoxins and fumonisin B1 in cassava and yam chips from Benin, West Africa. | 2008 | Int. J. Food Microbiol. | pmid:18160162 |
Gbore FA and Egbunike GN | Testicular and epididymal sperm reserves and sperm production of pubertal boars fed dietary fumonisin B(1). | 2008 | Anim. Reprod. Sci. | pmid:18155863 |
Shi L et al. | Involvement of sphingoid bases in mediating reactive oxygen intermediate production and programmed cell death in Arabidopsis. | 2007 | Cell Res. | pmid:18059378 |
Masini E et al. | Ceramide: a key signaling molecule in a Guinea pig model of allergic asthmatic response and airway inflammation. | 2008 | J. Pharmacol. Exp. Ther. | pmid:18042827 |
Dambolena JS et al. | Inhibitory effect of cyclic terpenes (limonene, menthol, menthone and thymol) on Fusarium verticillioides MRC 826 growth and fumonisin B1 biosynthesis. | 2008 | Toxicon | pmid:18037463 |
Deshmukh S et al. | Pathologic changes in extrahepatic organs and agglutinin response to Salmonella Gallinarum infection in Japanese quail fed Fusarium verticillioides culture material containing known levels of fumonisin B1. | 2007 | Avian Dis. | pmid:17992930 |
Yi F et al. | Mechanism of homocysteine-induced Rac1/NADPH oxidase activation in mesangial cells: role of guanine nucleotide exchange factor Vav2. | 2007 | Cell. Physiol. Biochem. | pmid:17982273 |
Karuna R and Sashidhar RB | The mycotoxin fumonisin B1 inhibits eukaryotic protein synthesis: in vitro and in vivo studies. | 2008 | Mycopathologia | pmid:17968675 |
Rumora L et al. | Mycotoxin fumonisin B1 alters cellular redox balance and signalling pathways in rat liver and kidney. | 2007 | Toxicology | pmid:17949882 |
Frisvad JC et al. | Fumonisin B2 production by Aspergillus niger. | 2007 | J. Agric. Food Chem. | pmid:17929891 |
Marin DE et al. | Fumonisin B1 alters cell cycle progression and interleukin-2 synthesis in swine peripheral blood mononuclear cells. | 2007 | Mol Nutr Food Res | pmid:17918165 |
Cai Q et al. | Validation of fumonisin biomarkers in F344 rats. | 2007 | Toxicol. Appl. Pharmacol. | pmid:17904604 |
Le Stunff H et al. | Recycling of sphingosine is regulated by the concerted actions of sphingosine-1-phosphate phosphohydrolase 1 and sphingosine kinase 2. | 2007 | J. Biol. Chem. | pmid:17895250 |
Orsi RB et al. | Effects of oral administration of aflatoxin B1 and fumonisin B1 in rabbits (Oryctolagus cuniculus). | 2007 | Chem. Biol. Interact. | pmid:17888418 |
Kim DH et al. | Elevation of sphingoid base 1-phosphate as a potential contributor to hepatotoxicity in fumonisin B1-exposed mice. | 2007 | Arch. Pharm. Res. | pmid:17879749 |
Klarić MS et al. | Cytotoxicity and apoptosis induced by fumonisin B(1), beauvericin and ochratoxin A in porcine kidney PK15 cells: effects of individual and combined treatment. | 2008 | Arch. Toxicol. | pmid:17879085 |
Xing LX et al. | [Effects of fumonisin on HLA-I expression on human peripheral blood mononuclear cells in vitro]. | 2007 | Xi Bao Yu Fen Zi Mian Yi Xue Za Zhi | pmid:17825220 |
Shier WT et al. | Toxicity of the mycotoxins fumonisins B1 and B2 and Alternaria alternata f. sp. lycopersici toxin (AAL) in cultured mammalian cells. | 1991 | Mycopathologia | pmid:1780003 |
Whitaker TB et al. | Evaluating the performance of sampling plans to detect fumonisin B1 in maize lots marketed in Nigeria. | 2007 Jul-Aug | J AOAC Int | pmid:17760343 |
Seiferlein M et al. | Hydrolyzed fumonisins HFB1 and HFB2 are acylated in vitro and in vivo by ceramide synthase to form cytotoxic N-acyl-metabolites. | 2007 | Mol Nutr Food Res | pmid:17729221 |
Adejumo TO et al. | Survey of maize from south-western Nigeria for zearalenone, alpha- and beta-zearalenols, fumonisin B1 and enniatins produced by Fusarium species. | 2007 | Food Addit Contam | pmid:17691013 |
Domijan AM et al. | The involvement of oxidative stress in ochratoxin A and fumonisin B1 toxicity in rats. | 2007 | Mol Nutr Food Res | pmid:17688296 |
Nelson PE et al. | Production of fumonisins by Fusarium moniliforme strains from various substrates and geographic areas. | 1991 | Appl. Environ. Microbiol. | pmid:1768112 |
Norred WP et al. | Effectiveness of ammonia treatment in detoxification of fumonisin-contaminated corn. | 1991 | Food Chem. Toxicol. | pmid:1765326 |
Bouhet S and Oswald IP | The intestine as a possible target for fumonisin toxicity. | 2007 | Mol Nutr Food Res | pmid:17642075 |
Tsegaye Y et al. | Arabidopsis mutants lacking long chain base phosphate lyase are fumonisin-sensitive and accumulate trihydroxy-18:1 long chain base phosphate. | 2007 | J. Biol. Chem. | pmid:17635905 |
Liu C et al. | Fumonisins production by Fusarium proliferatum strains isolated from asparagus crown. | 2007 | Mycopathologia | pmid:17629787 |
Ackermann T | Fast thin-layer chromatography systems for fumonisin isolation and identification. | 1991 | J Appl Toxicol | pmid:1761804 |
Abdel Nour AM et al. | Folate receptor and human reduced folate carrier expression in HepG2 cell line exposed to fumonisin B1 and folate deficiency. | 2007 | Carcinogenesis | pmid:17615259 |
Barbu A and Welsh N | Lipofection of insulin-producing RINm5F cells: methodological improvements. | 2007 | J Liposome Res | pmid:17613696 |
Hsiao SH et al. | Use of formalin-fixed tissues to determine fumonisin B1-induced sphingolipid alterations in swine. | 2007 | J. Vet. Diagn. Invest. | pmid:17609357 |
Lino CM et al. | Occurrence of fumonisins B1 and B2 in broa, typical Portuguese maize bread. | 2007 | Int. J. Food Microbiol. | pmid:17604863 |
Plattner RD et al. | Analysis of corn and cultured corn for fumonisin B1 by HPLC and GC/MS by four laboratories. | 1991 | J. Vet. Diagn. Invest. | pmid:1760472 |
del RÃo GarcÃa JC et al. | [Evaluation of the cytotoxicity of aflatoxin and fumonisin in swine intestinal cells]. | 2007 | Rev Iberoam Micol | pmid:17604433 |
Lee WK et al. | Cadmium-induced ceramide formation triggers calpain-dependent apoptosis in cultured kidney proximal tubule cells. | 2007 | Am. J. Physiol., Cell Physiol. | pmid:17596294 |
Feng H et al. | Functional characterization of the Arabidopsis eukaryotic translation initiation factor 5A-2 that plays a crucial role in plant growth and development by regulating cell division, cell growth, and cell death. | 2007 | Plant Physiol. | pmid:17513484 |
Kitatani K et al. | Mechanism of inhibition of sequestration of protein kinase C alpha/betaII by ceramide. Roles of ceramide-activated protein phosphatases and phosphorylation/dephosphorylation of protein kinase C alpha/betaII on threonine 638/641. | 2007 | J. Biol. Chem. | pmid:17504762 |
Loiseau N et al. | Fumonisin B1 exposure and its selective effect on porcine jejunal segment: sphingolipids, glycolipids and trans-epithelial passage disturbance. | 2007 | Biochem. Pharmacol. | pmid:17499218 |
Choi SE et al. | Involvement of glycogen synthase kinase-3beta in palmitate-induced human umbilical vein endothelial cell apoptosis. | 2007 | J. Vasc. Res. | pmid:17483602 |
Fodor J et al. | In vitro microbial metabolism of fumonisin B1. | 2007 | Food Addit Contam | pmid:17454115 |
Silva LJ et al. | Occurrence of fumonisins B1 and B2 in Portuguese maize and maize-based foods intended for human consumption. | 2007 | Food Addit Contam | pmid:17454111 |
Sjögren B and Svenningsson P | Depletion of the lipid raft constituents, sphingomyelin and ganglioside, decreases serotonin binding at human 5-HT7(a) receptors in HeLa cells. | 2007 | Acta Physiol (Oxf) | pmid:17428232 |
Burger HM et al. | Altered lipid parameters in hepatic subcellular membrane fractions induced by fumonisin B1. | 2007 | Lipids | pmid:17393230 |
Williams LD et al. | Fumonisin disruption of ceramide biosynthesis in maize roots and the effects on plant development and Fusarium verticillioides-induced seedling disease. | 2007 | J. Agric. Food Chem. | pmid:17381121 |
Sun G et al. | Fumonisin B1 contamination of home-grown corn in high-risk areas for esophageal and liver cancer in China. | 2007 | Food Addit Contam | pmid:17364919 |
Sedova IB and Tutel'ian VA | [Study of fumonisins B1 and B2 contamination of baby food]. | 2006 | Vopr Pitan | pmid:17313050 |
Klarić MS et al. | Lipid peroxidation and glutathione levels in porcine kidney PK15 cells after individual and combined treatment with fumonisin B(1), beauvericin and ochratoxin A. | 2007 | Basic Clin. Pharmacol. Toxicol. | pmid:17309518 |
Domijan AM et al. | Fumonisin B(1): oxidative status and DNA damage in rats. | 2007 | Toxicology | pmid:17291664 |
Keller KM et al. | The mycobiota and toxicity of equine feeds. | 2007 | Vet. Res. Commun. | pmid:17285246 |
Ariño A et al. | Natural occurrence of Fusarium species, fumonisin production by toxigenic strains, and concentrations of fumonisins B1, and B2 in conventional and organic maize grown in Spain. | 2007 | J. Food Prot. | pmid:17265874 |
Prasitchoke P et al. | Identification and characterization of a very long-chain fatty acid elongase gene in the methylotrophic yeast, Hansenula polymorpha. | 2007 | Gene | pmid:17236726 |
Oliveira GR et al. | Mycobiota in poultry feeds and natural occurrence of aflatoxins, fumonisins and zearalenone in the Rio de Janeiro State, Brazil. | 2006 | Mycopathologia | pmid:17123034 |
Kouadio JH et al. | Effects of combinations of Fusarium mycotoxins on the inhibition of macromolecular synthesis, malondialdehyde levels, DNA methylation and fragmentation, and viability in Caco-2 cells. | 2007 | Toxicon | pmid:17109910 |
Lock EA et al. | Caspase-dependent and -independent induction of phosphatidylserine externalization during apoptosis in human renal carcinoma Cak(1)-1 and A-498 cells. | 2007 | Toxicology | pmid:17097791 |
Suzuki H et al. | Inducible nitric oxide has protective effect on fumonisin B1 hepatotoxicity in mice via modulation of sphingosine kinase. | 2007 | Toxicology | pmid:17095132 |
Samapundo S et al. | The influence of modified atmospheres and their interaction with water activity on the radial growth and fumonisin B(1) production of Fusarium verticillioides and F. proliferatum on corn. Part II: The effect of initial headspace oxygen concentration. | 2007 | Int. J. Food Microbiol. | pmid:17084934 |
Samapundo S et al. | The influence of modified atmospheres and their interaction with water activity on the radial growth and fumonisin B(1) production of Fusarium verticillioides and F. proliferatum on corn. Part I: the effect of initial headspace carbon dioxide concentration. | 2007 | Int. J. Food Microbiol. | pmid:17084933 |
He Q et al. | S-adenosylmethionine or 5'-methylthioadenosine are unable to prevent fumonisin B1 hepatotoxicity in mice despite increased oxidation in liver. | 2006 Nov-Dec | J Appl Toxicol | pmid:17080400 |
Sjögren B et al. | Cholesterol depletion reduces serotonin binding and signaling via human 5-HT(7(a)) receptors. | 2006 | Eur. J. Pharmacol. | pmid:17064686 |
Kim DH et al. | Elevation of sphinganine 1-phosphate as a predictive biomarker for fumonisin exposure and toxicity in mice. | 2006 | J. Toxicol. Environ. Health Part A | pmid:17060094 |
He Q et al. | Ceramide synthase inhibition by fumonisin B1 treatment activates sphingolipid-metabolizing systems in mouse liver. | 2006 | Toxicol. Sci. | pmid:16960033 |
Hinojo MJ et al. | Fumonisin production in rice cultures of Fusarium verticillioides under different incubation conditions using an optimized analytical method. | 2006 | Food Microbiol. | pmid:16942995 |
Cheng YH et al. | Effect of fumonisins on macrophage immune functions and gene expression of cytokines in broilers. | 2006 | Arch Anim Nutr | pmid:16921924 |
Luongo D et al. | Interactive effects of fumonisin B1 and alpha-zearalenol on proliferation and cytokine expression in Jurkat T cells. | 2006 | Toxicol In Vitro | pmid:16899350 |
Bindschedler LV et al. | Peroxidase-dependent apoplastic oxidative burst in Arabidopsis required for pathogen resistance. | 2006 | Plant J. | pmid:16889645 |
Sharma RP et al. | Mice lacking both TNFalpha receptors show increased constitutive expression of IFNgamma: a possible reason for lack of protection from fumonisin B1 hepatotoxicity. | 2006 | Cytokine | pmid:16884913 |
Stockmann-Juvala H et al. | Fumonisin B1-induced apoptosis in neuroblastoma, glioblastoma and hypothalamic cell lines. | 2006 | Toxicology | pmid:16860453 |
Williams LD et al. | Fumonisin production and bioavailability to maize seedlings grown from seeds inoculated with Fusarium verticillioides and grown in natural soils. | 2006 | J. Agric. Food Chem. | pmid:16848565 |
Sewram V et al. | Mycotoxin contamination of dietary and medicinal wild plants in the Eastern Cape Province of South Africa. | 2006 | J. Agric. Food Chem. | pmid:16848564 |
Bouhet S et al. | Mycotoxin fumonisin B1 selectively down-regulates the basal IL-8 expression in pig intestine: in vivo and in vitro studies. | 2006 | Food Chem. Toxicol. | pmid:16843581 |
Bezuidenhout CC et al. | Multiplex PCR-based detection of potential fumonisin-producing Fusarium in traditional African vegetables. | 2006 | Environ. Toxicol. | pmid:16841320 |
Asrani RK et al. | Effects of feeding Fusarium verticillioides (formerly Fusarium moniliforme) culture material containing known levels of fumonisin B1 in Japanese quail (Coturnix coturnix japonica). | 2006 | Poult. Sci. | pmid:16830851 |
Riley RT et al. | International shipping of fumonisins from maize extracts on C18 sorbent. | 2006 | Food Addit Contam | pmid:16807208 |
Tessari EN et al. | Effects of aflatoxin B1 and fumonisin B1 on body weight, antibody titres and histology of broiler chicks. | 2006 | Br. Poult. Sci. | pmid:16787861 |
Giussani P et al. | Sphingosine-1-phosphate phosphohydrolase regulates endoplasmic reticulum-to-golgi trafficking of ceramide. | 2006 | Mol. Cell. Biol. | pmid:16782891 |
Keck BB and Bodine AB | The effects of fumonisin B1 on viability and mitogenic response of avian immune cells. | 2006 | Poult. Sci. | pmid:16776470 |
Marin DE et al. | Sex-related differences in the immune response of weanling piglets exposed to low doses of fumonisin extract. | 2006 | Br. J. Nutr. | pmid:16768843 |
Yazdanpanah H et al. | Human dietary exposure to fumonisin B1 from Iranian maize harvested during 1998-2000. | 2006 | Mycopathologia | pmid:16761187 |
Voss KA et al. | Fumonisin concentration and ceramide synthase inhibitory activity of corn, masa, and tortilla chips. | 2006 | J. Toxicol. Environ. Health Part A | pmid:16760143 |
Jiang T et al. | [Development of monoclonal antibody against fumonisin B1 and ELISA-kit of quantitative analysis for fumonisin B1]. | 2006 | Wei Sheng Yan Jiu | pmid:16758974 |
Sharma N et al. | Amelioration of fumonisin B1 hepatotoxicity in mice by depletion of T cells with anti-Thy-1.2. | 2006 | Toxicology | pmid:16690192 |
Norholm MH et al. | Expression of the Arabidopsis high-affinity hexose transporter STP13 correlates with programmed cell death. | 2006 | FEBS Lett. | pmid:16616142 |