fumonisin b1 is a lipid of Sphingolipids (SP) class. Fumonisin b1 is associated with abnormalities such as Infection, Kidney Diseases, Liver diseases, DERMATITIS HERPETIFORMIS, FAMILIAL and Malnutrition. The involved functions are known as Gene Expression, Anabolism, Signal, Biosynthetic Pathways and Regulation. Fumonisin b1 often locates in Body tissue, Microsomes, microsomal membrane, Protoplasm and Mitochondria. The associated genes with fumonisin b1 are Genome, P4HTM gene, FATE1 gene, BCL2 gene and TMEM132D gene. The related lipids are dihydroceramide, ceramide 1-phosphate, Sphingolipids, Fatty Acids and Palmitates.
To understand associated biological information of fumonisin b1, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
fumonisin b1 is suspected in Infection, Kidney Diseases, Liver diseases, DERMATITIS HERPETIFORMIS, FAMILIAL, Malnutrition, Celiac Disease and other diseases in descending order of the highest number of associated sentences.
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We collected disease MeSH terms mapped to the references associated with fumonisin b1
Lipid pathways are not clear in current pathway databases. We organized associated pathways with fumonisin b1 through full-text articles, including metabolic pathways or pathways of biological mechanisms.
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Associated locations are in red color. Not associated locations are in black.
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Function | Cross reference | Weighted score | Related literatures |
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Gene | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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Meivar-Levy I and Futerman AH | Up-regulation of neutral glycosphingolipid synthesis upon long term inhibition of ceramide synthesis by fumonisin B1. | 1999 | J. Biol. Chem. | pmid:9988695 |
Abel S and Gelderblom WC | Oxidative damage and fumonisin B1-induced toxicity in primary rat hepatocytes and rat liver in vivo. | 1998 | Toxicology | pmid:9928627 |
Schaafsma AW et al. | Analysis of Fusarium toxins in maize and wheat using thin layer chromatography. | 1998 | Mycopathologia | pmid:9926423 |
Wang E et al. | Fumonisin B1 consumption by rats causes reversible, dose-dependent increases in urinary sphinganine and sphingosine. | 1999 | J. Nutr. | pmid:9915902 |
Kedera CJ et al. | Incidence of Fusarium spp. and levels of fumonisin B1 in maize in western Kenya. | 1999 | Appl. Environ. Microbiol. | pmid:9872757 |
Gumprecht LA et al. | Development of fumonisin-induced hepatotoxicity and pulmonary edema in orally dosed swine: morphological and biochemical alterations. | 1998 Nov-Dec | Toxicol Pathol | pmid:9864095 |
Kutuzov MA et al. | Expression and characterization of PP7, a novel plant protein Ser/Thr phosphatase distantly related to RdgC/PPEF and PP5. | 1998 | FEBS Lett. | pmid:9862444 |
Gurung NK et al. | Effects of fumonisin B1-contaminated feeds on weanling angora goats. | 1998 | J. Anim. Sci. | pmid:9856397 |
Whitaker TB et al. | Variability associated with testing shelled corn for fumonisin. | 1998 Nov-Dec | J AOAC Int | pmid:9850578 |
Ali-Vehmas T et al. | Measurement of antibacterial activities of T-2 toxin, deoxynivalenol, ochratoxin A, aflatoxin B1 and fumonisin B1 using microtitration tray-based turbidimetric techniques. | 1998 | Zentralbl Veterinarmed A | pmid:9838857 |
Tsunoda M et al. | Fumonisin B1-induced increases in neurotransmitter metabolite levels in different brain regions of BALB/c mice. | 1998 | Comp. Biochem. Physiol. C, Pharmacol. Toxicol. Endocrinol. | pmid:9827064 |
Isogai C et al. | Analysis of bax protein in sphingosine-induced apoptosis in the human leukemic cell line TF1 and its bcl-2 transfectants. | 1998 | Exp. Hematol. | pmid:9808050 |
Sweeney MJ and Dobson AD | Mycotoxin production by Aspergillus, Fusarium and Penicillium species. | 1998 | Int. J. Food Microbiol. | pmid:9801191 |
Atroshi F et al. | Effects of tamoxifen, melatonin, coenzyme Q10, and L-carnitine supplementation on bacterial growth in the presence of mycotoxins. | 1998 | Pharmacol. Res. | pmid:9774492 |
de Nijs M et al. | Fumonisin B1 in maize for food production imported in The Netherlands. | 1998 May-Jun | Food Addit Contam | pmid:9764207 |
de Nijs M et al. | The occurrence of fumonisin B1 in maize-containing foods in The Netherlands. | 1998 May-Jun | Food Addit Contam | pmid:9764206 |
Norred WP et al. | Mycotoxins and health hazards: toxicological aspects and mechanism of action of fumonisins. | 1998 | J Toxicol Sci | pmid:9760455 |
Munkvold G et al. | Occurrence of fusaproliferin and beauvericin in Fusarium-contaminated livestock feed in Iowa. | 1998 | Appl. Environ. Microbiol. | pmid:9758820 |
Konoshima T et al. | Anti-tumor-promoting activity of majonoside-R2 from Vietnamese ginseng, Panax vietnamensis Ha et Grushv. (I). | 1998 | Biol. Pharm. Bull. | pmid:9743252 |
Ciacci-Zanella JR et al. | Characterization of cell-cycle arrest by fumonisin B1 in CV-1 cells. | 1998 Sep-Oct | Food Chem. Toxicol. | pmid:9737426 |
Akiyama H et al. | Quantitation of fumonisins in corn by HPLC with o-phthalaldehyde postcolumn derivatization and their identification by LC/MS. | 1997-1998 | Mycopathologia | pmid:9735014 |
Collins TF et al. | Effects of fumonisin B1 in pregnant rats. Part 2. | 1998 | Food Chem. Toxicol. | pmid:9734718 |
Czerwiecki L | [Determination of selected mycotoxins in food. II. Selection of optimal conditions for the determination of fumonisin B1 and B2 in corn products using high performance liquid chromatography]. | 1998 | Rocz Panstw Zakl Hig | pmid:9734229 |
Voss KA et al. | In vivo effects of fumonisin B1-producing and fumonisin B1-nonproducing Fusarium moniliforme isolates are similar: fumonisins B2 and B3 cause hepato- and nephrotoxicity in rats. | 1998 | Mycopathologia | pmid:9725030 |
DiPietrantonio AM et al. | Regulation of G1/S transition and induction of apoptosis in HL-60 leukemia cells by fenretinide (4HPR). | 1998 | Int. J. Cancer | pmid:9724094 |
Rosiles MR et al. | An outbreak of equine leukoencephalomalacia at Oaxaca, Mexico, associated with fumonisin B1. | 1998 | Zentralbl Veterinarmed A | pmid:9719762 |
Duncan K et al. | Improved fluorometric and chromatographic methods for the quantification of fumonisins B(1), B(2) and B(3). | 1998 | J Chromatogr A | pmid:9718705 |
Shephard GS | Chromatographic determination of the fumonisin mycotoxins. | 1998 | J Chromatogr A | pmid:9718704 |
Lee JY et al. | Cell-cycle-dependent changes in ceramide levels preceding retinoblastoma protein dephosphorylation in G2/M. | 1998 | Biochem. J. | pmid:9716505 |
Castelo MM et al. | Stability of fumonisins in thermally processed corn products. | 1998 | J. Food Prot. | pmid:9713766 |
Gamen S et al. | Granulysin-induced apoptosis. I. Involvement of at least two distinct pathways. | 1998 | J. Immunol. | pmid:9712041 |
Castelo MM et al. | Occurrence of fumonisins in corn-based food products. | 1998 | J. Food Prot. | pmid:9709253 |
Schwarz A and Futerman AH | Inhibition of sphingolipid synthesis, but not degradation, alters the rate of dendrite growth in cultured hippocampal neurons. | 1998 | Brain Res. Dev. Brain Res. | pmid:9693790 |
Ueda N et al. | Role of enhanced ceramide generation in DNA damage and cell death in chemical hypoxic injury to LLC-PK1 cells. | 1998 | Kidney Int. | pmid:9690206 |
pmid:9687259 | ||||
Penner JD et al. | Developmental toxicity of purified fumonisin B1 in pregnant Syrian hamsters. | 1998 May-Jun | J Appl Toxicol | pmid:9685049 |
Yu FY and Chu FS | Analysis of fumonisins and Alternaria alternata toxin by liquid chromatography-enzyme-linked immunosorbent assay. | 1998 Jul-Aug | J AOAC Int | pmid:9680700 |
Stack ME | Analysis of fumonisin B1 and its hydrolysis product in tortillas. | 1998 Jul-Aug | J AOAC Int | pmid:9680698 |
de Nijs M et al. | Assessment of human exposure to fumonisin B1. | 1998 | J. Food Prot. | pmid:9678173 |
van der Westhuizen L et al. | Inhibition of sphingolipid biosynthesis in rat primary hepatocyte cultures by fumonisin B1 and other structurally related compounds. | 1998 | Food Chem. Toxicol. | pmid:9674957 |
Hatch GM and McClarty G | Phospholipid composition of purified Chlamydia trachomatis mimics that of the eucaryotic host cell. | 1998 | Infect. Immun. | pmid:9673255 |
Rösner H | Significance of gangliosides in neuronal differentiation of neuroblastoma cells and neurite growth in tissue culture. | 1998 | Ann. N. Y. Acad. Sci. | pmid:9668353 |
Humpf HU et al. | Acylation of naturally occurring and synthetic 1-deoxysphinganines by ceramide synthase. Formation of N-palmitoyl-aminopentol produces a toxic metabolite of hydrolyzed fumonisin, AP1, and a new category of ceramide synthase inhibitor. | 1998 | J. Biol. Chem. | pmid:9668088 |
Tsunoda M et al. | Early fumonisin B1 toxicity in relation to disrupted sphingolipid metabolism in male BALB/c mice. | 1998 | J. Biochem. Mol. Toxicol. | pmid:9664234 |
Auzenne E et al. | Cytotoxic effects of sphingolipids as single or multi-modality agents on human melanoma and soft tissue sarcoma in vitro. | 1998 | Melanoma Res. | pmid:9664144 |
Collins TF et al. | Effects of fumonisin B1 in pregnant rats. | 1998 | Food Chem. Toxicol. | pmid:9662415 |
Mehta R et al. | Glutathione S-transferase-placental form expression and proliferation of hepatocytes in fumonisin B1-treated male and female Sprague-Dawley rats. | 1998 | Cancer Lett. | pmid:9652790 |
Garzotto M et al. | 12-O-tetradecanoylphorbol-13-acetate-induced apoptosis in LNCaP cells is mediated through ceramide synthase. | 1998 | Cancer Res. | pmid:9605775 |
Fazekas B et al. | Fumonisin B1 contamination of maize and experimental acute fumonisin toxicosis in pigs. | 1998 | Zentralblatt Veterinarmedizin Reihe B | pmid:9588111 |
Abado-Becognee K et al. | Cytotoxicity of fumonisin B1: implication of lipid peroxidation and inhibition of protein and DNA syntheses. | 1998 | Arch. Toxicol. | pmid:9587019 |
Mullett W et al. | Immunoassay of fumonisins by a surface plasmon resonance biosensor. | 1998 | Anal. Biochem. | pmid:9570825 |
Sahu SC et al. | Peroxidation of membrane lipids and oxidative DNA damage by fumonisin B1 in isolated rat liver nuclei. | 1998 | Cancer Lett. | pmid:9566705 |
Yin JJ et al. | Effects of fumonisin B1 on lipid peroxidation in membranes. | 1998 | Biochim. Biophys. Acta | pmid:9565668 |
Wolf G | Inhibition of cellular uptake of folate by blocking synthesis of the membrane folate receptor. | 1998 | Nutr. Rev. | pmid:9564182 |
Wieder T et al. | Induction of ceramide-mediated apoptosis by the anticancer phospholipid analog, hexadecylphosphocholine. | 1998 | J. Biol. Chem. | pmid:9556584 |
Lemmer ER et al. | Poor reporting of oocyte apoptosis. | 1998 | Nat. Med. | pmid:9546766 |
Dugyala RR et al. | Tumor necrosis factor-alpha as a contributor in fumonisin B1 toxicity. | 1998 | J. Pharmacol. Exp. Ther. | pmid:9536027 |
Prathapkumar SH et al. | Disease outbreak in laying hens arising from the consumption of fumonisin-contaminated food. | 1997 | Br. Poult. Sci. | pmid:9510989 |
Bucci TJ et al. | Renal effects of fumonisin mycotoxins in animals. | 1998 Jan-Feb | Toxicol Pathol | pmid:9502399 |
Sharma RP et al. | Demonstration of in-situ apoptosis in mouse liver and kidney after short-term repeated exposure to fumonisin B1. | 1997 | J. Comp. Pathol. | pmid:9502273 |
Shetty PH and Bhat RV | Sensitive method for the detection of fumonisin B1 in human urine. | 1998 | J. Chromatogr. B Biomed. Sci. Appl. | pmid:9498687 |
Schmelz EM et al. | Induction of apoptosis by fumonisin B1 in HT29 cells is mediated by the accumulation of endogenous free sphingoid bases. | 1998 | Toxicol. Appl. Pharmacol. | pmid:9473533 |
Vesonder RF and Wu W | Correlation of moniliformin, but not fumonisin B1 levels, in culture materials of Fusarium isolates to acute death in ducklings. | 1998 | Poult. Sci. | pmid:9469753 |
Hlywka JJ et al. | The use of the chicken embryo screening test and brine shrimp (Artemia salina) bioassays to assess the toxicity of fumonisin B1 mycotoxin. | 1997 Oct-Nov | Food Chem. Toxicol. | pmid:9463533 |
Bondy GS et al. | Toxicity of fumonisin B1 to B6C3F1 mice: a 14-day gavage study. | 1997 Oct-Nov | Food Chem. Toxicol. | pmid:9463532 |
Ueno Y et al. | Fumonisins as a possible contributory risk factor for primary liver cancer: a 3-year study of corn harvested in Haimen, China, by HPLC and ELISA. | 1997 | Food Chem. Toxicol. | pmid:9449219 |
Flynn TJ et al. | Assessment of the embryotoxic potential of the total hydrolysis product of fumonisin B1 using cultured organogenesis-staged rat embryos. | 1997 | Food Chem. Toxicol. | pmid:9449218 |
Bondy GS et al. | Gavage administration of the fungal toxin fumonisin B1 to female Sprague-Dawley rats. | 1998 | J. Toxicol. Environ. Health Part A | pmid:9444317 |
Keller SE et al. | Factors affecting the growth of Fusarium proliferatum and the production of fumonisin B1: oxygen and pH. | 1997 | J. Ind. Microbiol. Biotechnol. | pmid:9439006 |
LaBorde JB et al. | Lack of embryotoxicity of fumonisin B1 in New Zealand white rabbits. | 1997 | Fundam Appl Toxicol | pmid:9398494 |
Holcomb M and Thompson HC | Analysis of fumonisin B1 in rodent feed by CE with fluorescence detection of the FMOC derivative. | 1996 Jul-Aug | J Capillary Electrophor | pmid:9384738 |
Norred WP et al. | Mycotoxin-induced elevation of free sphingoid bases in precision-cut rat liver slices: specificity of the response and structure-activity relationships. | 1997 | Toxicol. Appl. Pharmacol. | pmid:9356308 |
Scott PM et al. | Evaluation of enzyme-linked immunosorbent assay for analysis of beer for fumonisins. | 1997 | Food Addit Contam | pmid:9328528 |
Tryphonas H et al. | Effects of fumonisin B1 on the immune system of sprague-dawley rats following a 14-day oral (gavage) exposure. | 1997 | Fundam Appl Toxicol | pmid:9325027 |
Strum JC et al. | Lipid second messengers. A role in cell growth regulation and cell cycle progression. | 1997 | Adv. Exp. Med. Biol. | pmid:9321986 |
Gelderblom WC et al. | Effect of fumonisin B1 on the levels and fatty acid composition of selected lipids in rat liver in vivo. | 1997 | Food Chem. Toxicol. | pmid:9301647 |
Tseng TC and Liu CY | Occurrence of fumonisin B1 and B2 in corn-based foodstuffs in Taiwan market. | 1997 | Mycopathologia | pmid:9299759 |
Jiménez M and Mateo R | Determination of mycotoxins produced by Fusarium isolates from banana fruits by capillary gas chromatography and high-performance liquid chromatography. | 1997 | J Chromatogr A | pmid:9299747 |
Ferguson SA et al. | Prenatal fumonisin (FB1) treatment in rats results in minimal maternal or offspring toxicity. | 1997 | Neurotoxicology | pmid:9291504 |
Wild CP et al. | Absence of a synergistic effect between fumonisin B1 and N-nitrosomethylbenzylamine in the induction of oesophageal papillomas in the rat. | 1997 | Nat. Toxins | pmid:9285918 |
Kubena LF et al. | Individual and combined effects of fumonisin B1 present in Fusarium moniliforme culture material and T-2 toxin or deoxynivalenol in broiler chicks. | 1997 | Poult. Sci. | pmid:9276886 |
Balsinde J et al. | Inflammatory activation of arachidonic acid signaling in murine P388D1 macrophages via sphingomyelin synthesis. | 1997 | J. Biol. Chem. | pmid:9252342 |
Rumbeiha WK and Oehme FW | Fumonisin exposure to Kansans through consumption of corn-based market foods. | 1997 | Vet Hum Toxicol | pmid:9251171 |
Piñeiro MS et al. | Fumonisin levels in Uruguayan corn products. | 1997 Jul-Aug | J AOAC Int | pmid:9241845 |
Knasmüller S et al. | Genotoxic effects of three Fusarium mycotoxins, fumonisin B1, moniliformin and vomitoxin in bacteria and in primary cultures of rat hepatocytes. | 1997 | Mutat. Res. | pmid:9219547 |
Stevens VL and Tang J | Fumonisin B1-induced sphingolipid depletion inhibits vitamin uptake via the glycosylphosphatidylinositol-anchored folate receptor. | 1997 | J. Biol. Chem. | pmid:9218430 |
Beier RC and Stanker LH | Molecular models for the stereochemical structures of fumonisin B1 and B2. | 1997 | Arch. Environ. Contam. Toxicol. | pmid:9216863 |
Guzman RE et al. | Chronic consumption of fumonisins derived from Fusarium moniliforme culture material: clinical and pathologic effects in swine. | 1997 | J. Vet. Diagn. Invest. | pmid:9211249 |
Bermudez AJ et al. | The individual and combined effects of the Fusarium mycotoxins moniliformin and fumonisin B1 in turkeys. | 1997 Apr-Jun | Avian Dis. | pmid:9201392 |
Suzuki A et al. | Sequential operation of ceramide synthesis and ICE cascade in CPT-11-initiated apoptotic death signaling. | 1997 | Exp. Cell Res. | pmid:9184074 |
Bhat RV et al. | A foodborne disease outbreak due to the consumption of moldy sorghum and maize containing fumonisin mycotoxins. | 1997 | J. Toxicol. Clin. Toxicol. | pmid:9140318 |
Kwon OS et al. | Effects of fumonisin B1 treatment on blood-brain barrier transfer in developing rats. | 1997 Mar-Apr | Neurotoxicol Teratol | pmid:9136132 |
Melcion D et al. | Study of the biosynthesis of fumonisins B1, B2 and B3 by different strains of Fusarium moniliforme. | 1997 | Lett. Appl. Microbiol. | pmid:9134779 |
Wu W and Vesonder RF | Inhibition of gluconeogenesis in cultured chicken embryo hepatocytes by Fusarium metabolites. | 1997 | Nat. Toxins | pmid:9131594 |
Guzman RE et al. | Dietary Fusarium moniliforme culture material induces in vitro tumor necrosis factor-alpha like activity in the sera of swine. | 1997 | Immunopharmacol Immunotoxicol | pmid:9130010 |
Scudamore KA et al. | Determination of mycotoxins in pet foods sold for domestic pets and wild birds using linked-column immunoassay clean-up and HPLC. | 1997 Feb-Mar | Food Addit Contam | pmid:9102350 |
Wiesner DA et al. | Anti-immunoglobulin-induced apoptosis in WEHI 231 cells involves the slow formation of ceramide from sphingomyelin and is blocked by bcl-XL. | 1997 | J. Biol. Chem. | pmid:9092523 |
Espada Y et al. | Fumonisin mycotoxicosis in broilers: plasma proteins and coagulation modifications. | 1997 Jan-Mar | Avian Dis. | pmid:9087322 |
Hirooka EY et al. | The natural occurrence of fumonisins in Brazilian corn kernels. | 1996 Feb-Mar | Food Addit Contam | pmid:9064243 |
Yoshizawa T et al. | Occurrence of fumonisins and aflatoxins in corn from Thailand. | 1996 Feb-Mar | Food Addit Contam | pmid:9064241 |