fumonisin b1

fumonisin b1 is a lipid of Sphingolipids (SP) class. Fumonisin b1 is associated with abnormalities such as Infection, Kidney Diseases, Liver diseases, DERMATITIS HERPETIFORMIS, FAMILIAL and Malnutrition. The involved functions are known as Gene Expression, Anabolism, Signal, Biosynthetic Pathways and Regulation. Fumonisin b1 often locates in Body tissue, Microsomes, microsomal membrane, Protoplasm and Mitochondria. The associated genes with fumonisin b1 are Genome, P4HTM gene, FATE1 gene, BCL2 gene and TMEM132D gene. The related lipids are dihydroceramide, ceramide 1-phosphate, Sphingolipids, Fatty Acids and Palmitates.

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Introduction

To understand associated biological information of fumonisin b1, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with fumonisin b1?

fumonisin b1 is suspected in Infection, Kidney Diseases, Liver diseases, DERMATITIS HERPETIFORMIS, FAMILIAL, Malnutrition, Celiac Disease and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with fumonisin b1

MeSH term MeSH ID Detail
Stomach Ulcer D013276 75 associated lipids
Adenocarcinoma D000230 166 associated lipids
Lung Diseases D008171 37 associated lipids
Lung Neoplasms D008175 171 associated lipids
Kidney Neoplasms D007680 29 associated lipids
Inflammation D007249 119 associated lipids
Fatty Liver D005234 48 associated lipids
Body Weight D001835 333 associated lipids
Esophageal Neoplasms D004938 20 associated lipids
Precancerous Conditions D011230 48 associated lipids
Per page 10 20 50 100 | Total 54

PubChem Associated disorders and diseases

What pathways are associated with fumonisin b1

Lipid pathways are not clear in current pathway databases. We organized associated pathways with fumonisin b1 through full-text articles, including metabolic pathways or pathways of biological mechanisms.

Related references are published most in these journals:

Pathway name Related literatures
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PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with fumonisin b1?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with fumonisin b1?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with fumonisin b1?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with fumonisin b1?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with fumonisin b1?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with fumonisin b1

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Per page 10 20 50 100 | Total 1278
Authors Title Published Journal PubMed Link
Meivar-Levy I and Futerman AH Up-regulation of neutral glycosphingolipid synthesis upon long term inhibition of ceramide synthesis by fumonisin B1. 1999 J. Biol. Chem. pmid:9988695
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Wang E et al. Fumonisin B1 consumption by rats causes reversible, dose-dependent increases in urinary sphinganine and sphingosine. 1999 J. Nutr. pmid:9915902
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Akiyama H et al. Quantitation of fumonisins in corn by HPLC with o-phthalaldehyde postcolumn derivatization and their identification by LC/MS. 1997-1998 Mycopathologia pmid:9735014
Collins TF et al. Effects of fumonisin B1 in pregnant rats. Part 2. 1998 Food Chem. Toxicol. pmid:9734718
Czerwiecki L [Determination of selected mycotoxins in food. II. Selection of optimal conditions for the determination of fumonisin B1 and B2 in corn products using high performance liquid chromatography]. 1998 Rocz Panstw Zakl Hig pmid:9734229
Voss KA et al. In vivo effects of fumonisin B1-producing and fumonisin B1-nonproducing Fusarium moniliforme isolates are similar: fumonisins B2 and B3 cause hepato- and nephrotoxicity in rats. 1998 Mycopathologia pmid:9725030
DiPietrantonio AM et al. Regulation of G1/S transition and induction of apoptosis in HL-60 leukemia cells by fenretinide (4HPR). 1998 Int. J. Cancer pmid:9724094
Rosiles MR et al. An outbreak of equine leukoencephalomalacia at Oaxaca, Mexico, associated with fumonisin B1. 1998 Zentralbl Veterinarmed A pmid:9719762
Duncan K et al. Improved fluorometric and chromatographic methods for the quantification of fumonisins B(1), B(2) and B(3). 1998 J Chromatogr A pmid:9718705
Shephard GS Chromatographic determination of the fumonisin mycotoxins. 1998 J Chromatogr A pmid:9718704
Lee JY et al. Cell-cycle-dependent changes in ceramide levels preceding retinoblastoma protein dephosphorylation in G2/M. 1998 Biochem. J. pmid:9716505
Castelo MM et al. Stability of fumonisins in thermally processed corn products. 1998 J. Food Prot. pmid:9713766
Gamen S et al. Granulysin-induced apoptosis. I. Involvement of at least two distinct pathways. 1998 J. Immunol. pmid:9712041
Castelo MM et al. Occurrence of fumonisins in corn-based food products. 1998 J. Food Prot. pmid:9709253
Schwarz A and Futerman AH Inhibition of sphingolipid synthesis, but not degradation, alters the rate of dendrite growth in cultured hippocampal neurons. 1998 Brain Res. Dev. Brain Res. pmid:9693790
Ueda N et al. Role of enhanced ceramide generation in DNA damage and cell death in chemical hypoxic injury to LLC-PK1 cells. 1998 Kidney Int. pmid:9690206
pmid:9687259
Penner JD et al. Developmental toxicity of purified fumonisin B1 in pregnant Syrian hamsters. 1998 May-Jun J Appl Toxicol pmid:9685049
Yu FY and Chu FS Analysis of fumonisins and Alternaria alternata toxin by liquid chromatography-enzyme-linked immunosorbent assay. 1998 Jul-Aug J AOAC Int pmid:9680700
Stack ME Analysis of fumonisin B1 and its hydrolysis product in tortillas. 1998 Jul-Aug J AOAC Int pmid:9680698
de Nijs M et al. Assessment of human exposure to fumonisin B1. 1998 J. Food Prot. pmid:9678173
van der Westhuizen L et al. Inhibition of sphingolipid biosynthesis in rat primary hepatocyte cultures by fumonisin B1 and other structurally related compounds. 1998 Food Chem. Toxicol. pmid:9674957
Hatch GM and McClarty G Phospholipid composition of purified Chlamydia trachomatis mimics that of the eucaryotic host cell. 1998 Infect. Immun. pmid:9673255
Rösner H Significance of gangliosides in neuronal differentiation of neuroblastoma cells and neurite growth in tissue culture. 1998 Ann. N. Y. Acad. Sci. pmid:9668353
Humpf HU et al. Acylation of naturally occurring and synthetic 1-deoxysphinganines by ceramide synthase. Formation of N-palmitoyl-aminopentol produces a toxic metabolite of hydrolyzed fumonisin, AP1, and a new category of ceramide synthase inhibitor. 1998 J. Biol. Chem. pmid:9668088
Tsunoda M et al. Early fumonisin B1 toxicity in relation to disrupted sphingolipid metabolism in male BALB/c mice. 1998 J. Biochem. Mol. Toxicol. pmid:9664234
Auzenne E et al. Cytotoxic effects of sphingolipids as single or multi-modality agents on human melanoma and soft tissue sarcoma in vitro. 1998 Melanoma Res. pmid:9664144
Collins TF et al. Effects of fumonisin B1 in pregnant rats. 1998 Food Chem. Toxicol. pmid:9662415
Mehta R et al. Glutathione S-transferase-placental form expression and proliferation of hepatocytes in fumonisin B1-treated male and female Sprague-Dawley rats. 1998 Cancer Lett. pmid:9652790
Garzotto M et al. 12-O-tetradecanoylphorbol-13-acetate-induced apoptosis in LNCaP cells is mediated through ceramide synthase. 1998 Cancer Res. pmid:9605775
Fazekas B et al. Fumonisin B1 contamination of maize and experimental acute fumonisin toxicosis in pigs. 1998 Zentralblatt Veterinarmedizin Reihe B pmid:9588111
Abado-Becognee K et al. Cytotoxicity of fumonisin B1: implication of lipid peroxidation and inhibition of protein and DNA syntheses. 1998 Arch. Toxicol. pmid:9587019