| MeSH term | MeSH ID | Detail |
|---|---|---|
| Stomach Ulcer | D013276 | 75 associated lipids |
| Adenocarcinoma | D000230 | 166 associated lipids |
| Lung Diseases | D008171 | 37 associated lipids |
| Lung Neoplasms | D008175 | 171 associated lipids |
| Kidney Neoplasms | D007680 | 29 associated lipids |
| Inflammation | D007249 | 119 associated lipids |
| Fatty Liver | D005234 | 48 associated lipids |
| Body Weight | D001835 | 333 associated lipids |
| Esophageal Neoplasms | D004938 | 20 associated lipids |
| Precancerous Conditions | D011230 | 48 associated lipids |
fumonisin b1
fumonisin b1 is a lipid of Sphingolipids (SP) class. Fumonisin b1 is associated with abnormalities such as Infection, Kidney Diseases, Liver diseases, DERMATITIS HERPETIFORMIS, FAMILIAL and Malnutrition. The involved functions are known as Gene Expression, Anabolism, Signal, Biosynthetic Pathways and Regulation. Fumonisin b1 often locates in Body tissue, Microsomes, microsomal membrane, Protoplasm and Mitochondria. The associated genes with fumonisin b1 are Genome, P4HTM gene, FATE1 gene, BCL2 gene and TMEM132D gene. The related lipids are dihydroceramide, ceramide 1-phosphate, Sphingolipids, Fatty Acids and Palmitates.
Cross Reference
Introduction
To understand associated biological information of fumonisin b1, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with fumonisin b1?
fumonisin b1 is suspected in Infection, Kidney Diseases, Liver diseases, DERMATITIS HERPETIFORMIS, FAMILIAL, Malnutrition, Celiac Disease and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
- Am. J. Physiol. Heart Circ. Physiol. (1)
- Am. J. Physiol. Regul. Integr. Comp. Physiol. (1)
- Cancer Res. (1)
- Others (5)
| Disease | Cross reference | Weighted score | Related literature |
|---|
Loading... please refresh the page if content is not showing up.
Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with fumonisin b1
PubChem Associated disorders and diseases
What pathways are associated with fumonisin b1
Lipid pathways are not clear in current pathway databases. We organized associated pathways with fumonisin b1 through full-text articles, including metabolic pathways or pathways of biological mechanisms.
Related references are published most in these journals:
| Pathway name | Related literatures |
|---|
Loading... please refresh the page if content is not showing up.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with fumonisin b1?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
Loading... please refresh the page if content is not showing up.
What functions are associated with fumonisin b1?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with fumonisin b1?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
|---|
Loading... please refresh the page if content is not showing up.
What genes are associated with fumonisin b1?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with fumonisin b1?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with fumonisin b1
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Czerwiecki L | [Determination of selected mycotoxins in food. II. Selection of optimal conditions for the determination of fumonisin B1 and B2 in corn products using high performance liquid chromatography]. | 1998 | Rocz Panstw Zakl Hig | pmid:9734229 |
| Maekawa M et al. | Staurosporines decrease ORMDL proteins and enhance sphingomyelin synthesis resulting in depletion of plasmalemmal phosphatidylserine. | 2016 | Sci Rep | pmid:27805006 |
| Xue KS et al. | Mitigation of Fumonisin Biomarkers by Green Tea Polyphenols in a High-Risk Population of Hepatocellular Carcinoma. | 2015 | Sci Rep | pmid:26626148 |
| Baron CL and Malhotra V | Role of diacylglycerol in PKD recruitment to the TGN and protein transport to the plasma membrane. | 2002 | Science | pmid:11729268 |
| Zhang X et al. | [Determination of fumonisins B1 and B2 in corn by high performance liquid chromatography with post-column derivatization method]. | 2012 | Se Pu | pmid:23256381 |
| Xia QZ et al. | [Spontaneous and induced programmed cell death in suspension cell cultures of cotton (Gossypium hirsutum L.)]. | 2005 | Shi Yan Sheng Wu Xue Bao | pmid:16231696 |
| Cuzzocrea S et al. | Inhibition of ceramide biosynthesis ameliorates pathological consequences of spinal cord injury. | 2009 | Shock | pmid:18838947 |
| Cuzzocrea S et al. | Fumonisin b1 reduces the development of multiple organ failure induced by zymosan in mice. | 2009 | Shock | pmid:18650782 |
| Suga K et al. | [Analysis of fumonisin B1 and B2 in beer and raw materials of beer by liquid chromatography/tandem mass spectrometry]. | 2004 | Shokuhin Eiseigaku Zasshi | pmid:15678940 |
| Yoshinari T et al. | Inter-laboratory study of an LC-MS/MS method for simultaneous determination of fumonisin B1, B2 and B3 in corn. | 2013 | Shokuhin Eiseigaku Zasshi | pmid:24025204 |
| Jiménez M et al. | Characterization of Gibberella fujikuroi complex isolates by fumonisin B1 and B2 analysis and by RAPD and restriction analysis of PCR-amplified internal transcribed spacers of ribosomal DNA. | 2000 | Syst. Appl. Microbiol. | pmid:11249025 |
| Hinojo MJ et al. | Utility of the polymerase chain reaction-restriction fragment length polymorphisms of the intergenic spacer region of the rDNA for characterizing Gibberella fujikuroi isolates. | 2004 | Syst. Appl. Microbiol. | pmid:15612625 |
| Shu M et al. | Anti-idiotypic nanobody: A strategy for development of sensitive and green immunoassay for Fumonisin Bâ‚. | 2015 | Talanta | pmid:26078175 |
| Wu S et al. | Homogenous detection of fumonisin B(1) with a molecular beacon based on fluorescence resonance energy transfer between NaYF4: Yb, Ho upconversion nanoparticles and gold nanoparticles. | 2013 | Talanta | pmid:24148452 |
| Di Nardo F et al. | A fluorescent immunochromatographic strip test using Quantum Dots for fumonisins detection. | 2016 | Talanta | pmid:26838431 |
| Kozutsumi Y et al. | [Sphingolipid probe]. | 2002 | Tanpakushitsu Kakusan Koso | pmid:11915351 |
| Zomborszky-Kovács M et al. | Preliminary communication: examination of the harmful effect to fetuses of fumonisin B(1) in pregnant sows. | 2000 | Teratog., Carcinog. Mutagen. | pmid:10992276 |
| Sadler TW et al. | Prevention of fumonisin B1-induced neural tube defects by folic acid. | 2002 | Teratology | pmid:12353213 |
| Cortinovis C et al. | Effects of fumonisin B1 alone and combined with deoxynivalenol or zearalenone on porcine granulosa cell proliferation and steroid production. | 2014 | Theriogenology | pmid:24576714 |
| Luongo D et al. | Interactive effects of fumonisin B1 and alpha-zearalenol on proliferation and cytokine expression in Jurkat T cells. | 2006 | Toxicol In Vitro | pmid:16899350 |
| Minervini F et al. | Toxic effects induced by mycotoxin fumonisin B1 on equine spermatozoa: assessment of viability, sperm chromatin structure stability, ROS production and motility. | 2010 | Toxicol In Vitro | pmid:20541003 |
| Bernabucci U et al. | Aflatoxin B1 and fumonisin B1 affect the oxidative status of bovine peripheral blood mononuclear cells. | 2011 | Toxicol In Vitro | pmid:21256206 |
| Suzuki A and Tsutomi Y | Inductions of fibroblast-like morphology and high growth activity by low-dose CPT-11 in PC12 cells: role of tenascin. | 2000 | Toxicol In Vitro | pmid:10906440 |
| Minervini F et al. | Toxicity and apoptosis induced by the mycotoxins nivalenol, deoxynivalenol and fumonisin B1 in a human erythroleukemia cell line. | 2004 | Toxicol In Vitro | pmid:14630058 |
| Sancak D and Ozden S | Global histone modifications in Fumonisin B1 exposure in rat kidney epithelial cells. | 2015 | Toxicol In Vitro | pmid:26208285 |
| Pósa R et al. | A comparative pathological finding in pigs exposed to fumonisin B1 and/or Mycoplasma hyopneumoniae. | 2016 | Toxicol Ind Health | pmid:25107460 |
| Hard GC et al. | Rat kidney pathology induced by chronic exposure to fumonisin B1 includes rare variants of renal tubule tumor. | 2001 May-Jun | Toxicol Pathol | pmid:11442024 |
| Bucci TJ et al. | Renal effects of fumonisin mycotoxins in animals. | 1998 Jan-Feb | Toxicol Pathol | pmid:9502399 |
| Gumprecht LA et al. | Development of fumonisin-induced hepatotoxicity and pulmonary edema in orally dosed swine: morphological and biochemical alterations. | 1998 Nov-Dec | Toxicol Pathol | pmid:9864095 |
| He Q et al. | Fumonisin-induced tumor necrosis factor-alpha expression in a porcine kidney cell line is independent of sphingoid base accumulation induced by ceramide synthase inhibition. | 2001 | Toxicol. Appl. Pharmacol. | pmid:11437650 |
| Yeung JM et al. | Fumonisin B1 induces protein kinase C translocation via direct interaction with diacylglycerol binding site. | 1996 | Toxicol. Appl. Pharmacol. | pmid:8917690 |
| Martinez-Larrañaga MR et al. | Induction of cytochrome P4501A1 and P4504A1 activities and peroxisomal proliferation by fumonisin B1. | 1996 | Toxicol. Appl. Pharmacol. | pmid:8917691 |
| Howard PC et al. | Comparison of the toxicity of several fumonisin derivatives in a 28-day feeding study with female B6C3F(1) mice. | 2002 | Toxicol. Appl. Pharmacol. | pmid:12498732 |
| Liu BH et al. | The effects of mycotoxins, fumonisin B1 and aflatoxin B1, on primary swine alveolar macrophages. | 2002 | Toxicol. Appl. Pharmacol. | pmid:12009859 |
| Ramasamy S et al. | Fumonisin B1 alters sphingolipid metabolism and disrupts the barrier function of endothelial cells in culture. | 1995 | Toxicol. Appl. Pharmacol. | pmid:7645031 |
| Riley RT et al. | Alteration of tissue and serum sphinganine to sphingosine ratio: an early biomarker of exposure to fumonisin-containing feeds in pigs. | 1993 | Toxicol. Appl. Pharmacol. | pmid:8430417 |
| Cai Q et al. | Validation of fumonisin biomarkers in F344 rats. | 2007 | Toxicol. Appl. Pharmacol. | pmid:17904604 |
| Constable PD et al. | Ingestion of fumonisin B1-containing culture material decreases cardiac contractility and mechanical efficiency in swine. | 2000 | Toxicol. Appl. Pharmacol. | pmid:10652243 |
| Mobio TA et al. | Epigenetic properties of fumonisin B(1): cell cycle arrest and DNA base modification in C6 glioma cells. | 2000 | Toxicol. Appl. Pharmacol. | pmid:10739748 |
| Suzuki CA et al. | The effects of fumonisin B1 on several markers of nephrotoxicity in rats. | 1995 | Toxicol. Appl. Pharmacol. | pmid:7645015 |
| Schmelz EM et al. | Induction of apoptosis by fumonisin B1 in HT29 cells is mediated by the accumulation of endogenous free sphingoid bases. | 1998 | Toxicol. Appl. Pharmacol. | pmid:9473533 |
| Norred WP et al. | Mycotoxin-induced elevation of free sphingoid bases in precision-cut rat liver slices: specificity of the response and structure-activity relationships. | 1997 | Toxicol. Appl. Pharmacol. | pmid:9356308 |
| Gardner NM et al. | Elevated nuclear sphingoid base-1-phosphates and decreased histone deacetylase activity after fumonisin B1 treatment in mouse embryonic fibroblasts. | 2016 | Toxicol. Appl. Pharmacol. | pmid:26905748 |
| Carlson DB et al. | Fumonisin B1 promotes aflatoxin B1 and N-methyl-N'-nitro-nitrosoguanidine-initiated liver tumors in rainbow trout. | 2001 | Toxicol. Appl. Pharmacol. | pmid:11264020 |
| Yoo HS et al. | Elevated sphingoid bases and complex sphingolipid depletion as contributing factors in fumonisin-induced cytotoxicity. | 1996 | Toxicol. Appl. Pharmacol. | pmid:8658522 |
| Kim MS et al. | Fumonisin B(1) induces apoptosis in LLC-PK(1) renal epithelial cells via a sphinganine- and calmodulin-dependent pathway. | 2001 | Toxicol. Appl. Pharmacol. | pmid:11601888 |
| Ferrante MC et al. | Effect of fumonisin B1 on structure and function of macrophage plasma membrane. | 2002 | Toxicol. Lett. | pmid:11888701 |
| Bondy GS et al. | Retrospective evaluation of serum ornithine carbamyltransferase activity as an index of hepatotoxicity in toxicological studies with rats. | 2000 | Toxicol. Lett. | pmid:10713481 |
| Raynal M et al. | Effects of fumonisin B1 present in Fusarium moniliforme culture material on drug metabolising enzyme activities in ducks. | 2001 | Toxicol. Lett. | pmid:11369472 |
| Wan LY et al. | Individual and combined effects of Fusarium toxins on the mRNA expression of pro-inflammatory cytokines in swine jejunal epithelial cells. | 2013 | Toxicol. Lett. | pmid:23688591 |
| Steyn PS | Mycotoxins, general view, chemistry and structure. | 1995 | Toxicol. Lett. | pmid:8597152 |
| Kuiper-Goodman T | Mycotoxins: risk assessment and legislation. | 1995 | Toxicol. Lett. | pmid:8597153 |
| Clarke R et al. | High content analysis: a sensitive tool to detect and quantify the cytotoxic, synergistic and antagonistic effects of chemical contaminants in foods. | 2015 | Toxicol. Lett. | pmid:25623391 |
| Chuturgoon AA et al. | Fumonisin Bâ‚ modulates expression of human cytochrome P450 1b1 in human hepatoma (Hepg2) cells by repressing Mir-27b. | 2014 | Toxicol. Lett. | pmid:24614526 |
| Fernández-Blanco C et al. | An in vitro investigation on the cytotoxic and nuclear receptor transcriptional activity of the mycotoxins fumonisin B1 and beauvericin. | 2016 | Toxicol. Lett. | pmid:27234500 |
| Chuturgoon AA et al. | Fumonisin Bâ‚ inhibits apoptosis in HepG2 cells by inducing Birc-8/ILP-2. | 2015 | Toxicol. Lett. | pmid:25800559 |
| Bouhet S et al. | The mycotoxin fumonisin B1 alters the proliferation and the barrier function of porcine intestinal epithelial cells. | 2004 | Toxicol. Sci. | pmid:14600282 |
| Taranu I et al. | Mycotoxin fumonisin B1 alters the cytokine profile and decreases the vaccinal antibody titer in pigs. | 2005 | Toxicol. Sci. | pmid:15659571 |
| Dragan YP et al. | Implications of apoptosis for toxicity, carcinogenicity, and risk assessment: fumonisin B(1) as an example. | 2001 | Toxicol. Sci. | pmid:11294969 |
| He Q et al. | Silymarin protects against liver damage in BALB/c mice exposed to fumonisin B1 despite increasing accumulation of free sphingoid bases. | 2004 | Toxicol. Sci. | pmid:15103051 |
| He Q et al. | Ceramide synthase inhibition by fumonisin B1 treatment activates sphingolipid-metabolizing systems in mouse liver. | 2006 | Toxicol. Sci. | pmid:16960033 |
| Enongene EN et al. | Persistence and reversibility of the elevation in free sphingoid bases induced by fumonisin inhibition of ceramide synthase. | 2002 | Toxicol. Sci. | pmid:12011476 |
| Voss KA et al. | Reproductive and sphingolipid metabolic effects of fumonisin B(1) and its alkaline hydrolysis product in LM/Bc mice: hydrolyzed fumonisin B(1) did not cause neural tube defects. | 2009 | Toxicol. Sci. | pmid:19783636 |
| Voss KA et al. | Toxic effects of fumonisin in mouse liver are independent of the peroxisome proliferator-activated receptor alpha. | 2006 | Toxicol. Sci. | pmid:16221962 |
| Wan LY et al. | Modulation of mucin mRNA (MUC5AC and MUC5B) expression and protein production and secretion in Caco-2/HT29-MTX co-cultures following exposure to individual and combined Fusarium mycotoxins. | 2014 | Toxicol. Sci. | pmid:24496642 |
| Mathur S et al. | Fumonisin B(1) increases serum sphinganine concentration but does not alter serum sphingosine concentration or induce cardiovascular changes in milk-fed calves. | 2001 | Toxicol. Sci. | pmid:11248151 |
| Mathur S et al. | Fumonisin B(1) is hepatotoxic and nephrotoxic in milk-fed calves. | 2001 | Toxicol. Sci. | pmid:11248152 |
| Gelderblom WC et al. | Interaction of fumonisin B(1) and aflatoxin B(1) in a short-term carcinogenesis model in rat liver. | 2002 | Toxicology | pmid:11836022 |
| Bhandari N and Sharma RP | Fumonisin B(1)-induced alterations in cytokine expression and apoptosis signaling genes in mouse liver and kidney after an acute exposure. | 2002 | Toxicology | pmid:11882348 |
| Bailly JD et al. | Toxicity of Fusarium moniliforme culture material containing known levels of fumonisin B1 in ducks. | 2001 | Toxicology | pmid:11376861 |
| Sharma N et al. | Augmented fumonisin B1 toxicity in co-cultures: evidence for crosstalk between macrophages and non-parenchymatous liver epithelial cells involving proinflammatory cytokines. | 2004 | Toxicology | pmid:15363598 |
| Stockmann-Juvala H et al. | Fumonisin B1-induced toxicity and oxidative damage in U-118MG glioblastoma cells. | 2004 | Toxicology | pmid:15337581 |
| Creppy EE et al. | Synergistic effects of fumonisin B1 and ochratoxin A: are in vitro cytotoxicity data predictive of in vivo acute toxicity? | 2004 | Toxicology | pmid:15297026 |
| Gelderblom WC et al. | Toxicological effects in rats chronically fed low dietary levels of fumonisin B(1). | 2001 | Toxicology | pmid:11295254 |
| Stockmann-Juvala H et al. | Fumonisin B1-induced apoptosis in neuroblastoma, glioblastoma and hypothalamic cell lines. | 2006 | Toxicology | pmid:16860453 |
| Domijan AM et al. | Standard and Fpg-modified comet assay in kidney cells of ochratoxin A- and fumonisin B(1)-treated rats. | 2006 | Toxicology | pmid:16497426 |
| Theumer MG et al. | Subchronic mycotoxicoses in Wistar rats: assessment of the in vivo and in vitro genotoxicity induced by fumonisins and aflatoxin B(1), and oxidative stress biomarkers status. | 2010 | Toxicology | pmid:20015463 |
| Lock EA et al. | Caspase-dependent and -independent induction of phosphatidylserine externalization during apoptosis in human renal carcinoma Cak(1)-1 and A-498 cells. | 2007 | Toxicology | pmid:17097791 |
| Sharma N et al. | Amelioration of fumonisin B1 hepatotoxicity in mice by depletion of T cells with anti-Thy-1.2. | 2006 | Toxicology | pmid:16690192 |
| van der Westhuizen L et al. | Disruption of sphingolipid biosynthesis in hepatocyte nodules: selective proliferative stimulus induced by fumonisin B1. | 2004 | Toxicology | pmid:15158565 |
| Gelderblom WC et al. | Cancer initiating properties of fumonisin B1 in a short-term rat liver carcinogenesis assay. | 2008 | Toxicology | pmid:18616970 |
| Gopee NV and Sharma RP | Sphingoid bases and their phosphates: transient activation and delayed repression of protein kinase C isoforms and their possible involvement in fumonisin B1 cytotoxicity. | 2003 | Toxicology | pmid:12699912 |
| Mobio TA et al. | Comparative study of the toxic effects of fumonisin B1 in rat C6 glioma cells and p53-null mouse embryo fibroblasts. | 2003 | Toxicology | pmid:12504343 |
| Theumer MG et al. | Immunobiological effects of AFB1 and AFB1-FB1 mixture in experimental subchronic mycotoxicoses in rats. | 2003 | Toxicology | pmid:12604180 |
| Domijan AM et al. | Fumonisin B(1): oxidative status and DNA damage in rats. | 2007 | Toxicology | pmid:17291664 |
| Rumora L et al. | Mycotoxin fumonisin B1 alters cellular redox balance and signalling pathways in rat liver and kidney. | 2007 | Toxicology | pmid:17949882 |
| Kouadio JH et al. | Comparative study of cytotoxicity and oxidative stress induced by deoxynivalenol, zearalenone or fumonisin B1 in human intestinal cell line Caco-2. | 2005 | Toxicology | pmid:16019124 |
| Sharma RP et al. | Tolerance to fumonisin toxicity in a mouse strain lacking the P75 tumor necrosis factor receptor. | 2000 | Toxicology | pmid:10755704 |
| Biswal SS et al. | Changes in ceramide and sphingomyelin following fludarabine treatment of human chronic B-cell leukemia cells. | 2000 | Toxicology | pmid:11118669 |
| Chuturgoon A et al. | Fumonisin B1 induces global DNA hypomethylation in HepG2 cells - An alternative mechanism of action. | 2014 | Toxicology | pmid:24280379 |
| Suzuki H et al. | Inducible nitric oxide has protective effect on fumonisin B1 hepatotoxicity in mice via modulation of sphingosine kinase. | 2007 | Toxicology | pmid:17095132 |
| Voss KA et al. | The role of tumor necrosis factor alpha and the peroxisome proliferator-activated receptor alpha in modulating the effects of fumonisin in mouse liver. | 2006 | Toxicology | pmid:16574297 |
| Sharma RP et al. | Lupus-prone NZBWF1/J mice, defective in cytokine signaling, are resistant to fumonisin hepatotoxicity despite accumulation of liver sphinganine. | 2005 | Toxicology | pmid:16159691 |
| Abel S and Gelderblom WC | Oxidative damage and fumonisin B1-induced toxicity in primary rat hepatocytes and rat liver in vivo. | 1998 | Toxicology | pmid:9928627 |
| Romero A et al. | Mycotoxins modify the barrier function of Caco-2 cells through differential gene expression of specific claudin isoforms: Protective effect of illite mineral clay. | 2016 | Toxicology | pmid:27153755 |
| He Q et al. | Fumonisin B1 hepatotoxicity in mice is attenuated by depletion of Kupffer cells by gadolinium chloride. | 2005 | Toxicology | pmid:15590129 |
| Gumprecht LA et al. | Species and organ specificity of fumonisin-induced endothelial alterations: potential role in porcine pulmonary edema. | 2001 | Toxicology | pmid:11246126 |
| Sharma RP et al. | Decreased fumonisin hepatotoxicity in mice with a targeted deletion of tumor necrosis factor receptor 1. | 2001 | Toxicology | pmid:11250056 |
| Bhandari N et al. | Gender-related differences in subacute fumonisin B1 hepatotoxicity in BALB/c mice. | 2001 | Toxicology | pmid:11522378 |
| Mary VS et al. | Reactive oxygen species sources and biomolecular oxidative damage induced by aflatoxin B1 and fumonisin B1 in rat spleen mononuclear cells. | 2012 | Toxicology | pmid:22981896 |