| MeSH term | MeSH ID | Detail |
|---|---|---|
| Stomach Ulcer | D013276 | 75 associated lipids |
| Adenocarcinoma | D000230 | 166 associated lipids |
| Lung Diseases | D008171 | 37 associated lipids |
| Lung Neoplasms | D008175 | 171 associated lipids |
| Kidney Neoplasms | D007680 | 29 associated lipids |
| Inflammation | D007249 | 119 associated lipids |
| Fatty Liver | D005234 | 48 associated lipids |
| Body Weight | D001835 | 333 associated lipids |
| Esophageal Neoplasms | D004938 | 20 associated lipids |
| Precancerous Conditions | D011230 | 48 associated lipids |
fumonisin b1
fumonisin b1 is a lipid of Sphingolipids (SP) class. Fumonisin b1 is associated with abnormalities such as Infection, Kidney Diseases, Liver diseases, DERMATITIS HERPETIFORMIS, FAMILIAL and Malnutrition. The involved functions are known as Gene Expression, Anabolism, Signal, Biosynthetic Pathways and Regulation. Fumonisin b1 often locates in Body tissue, Microsomes, microsomal membrane, Protoplasm and Mitochondria. The associated genes with fumonisin b1 are Genome, P4HTM gene, FATE1 gene, BCL2 gene and TMEM132D gene. The related lipids are dihydroceramide, ceramide 1-phosphate, Sphingolipids, Fatty Acids and Palmitates.
Cross Reference
Introduction
To understand associated biological information of fumonisin b1, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with fumonisin b1?
fumonisin b1 is suspected in Infection, Kidney Diseases, Liver diseases, DERMATITIS HERPETIFORMIS, FAMILIAL, Malnutrition, Celiac Disease and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with fumonisin b1
PubChem Associated disorders and diseases
What pathways are associated with fumonisin b1
Lipid pathways are not clear in current pathway databases. We organized associated pathways with fumonisin b1 through full-text articles, including metabolic pathways or pathways of biological mechanisms.
Related references are published most in these journals:
| Pathway name | Related literatures |
|---|
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PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with fumonisin b1?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
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What functions are associated with fumonisin b1?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
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What lipids are associated with fumonisin b1?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
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What genes are associated with fumonisin b1?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with fumonisin b1?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with fumonisin b1
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Basso K et al. | Deoxynivanelol and fumonisin, alone or in combination, induce changes on intestinal junction complexes and in E-cadherin expression. | 2013 | Toxins (Basel) | pmid:24287571 |
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| Ficheux AS et al. | Co-exposure of Fusarium mycotoxins: in vitro myelotoxicity assessment on human hematopoietic progenitors. | 2012 | Toxicon | pmid:22921581 |
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| Sauviat MP et al. | Fumonisin, a toxin from the fungus Fusarium moniliforme sheld, blocks both the calcium current and the mechanical activity in frog atrial muscle. | 1991 | Toxicon | pmid:1658988 |
| Shephard GS et al. | Fate of a single dose of the 14C-labelled mycotoxin, fumonisin B1, in rats. | 1992 | Toxicon | pmid:1509495 |
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| Dambolena JS et al. | Inhibitory effect of cyclic terpenes (limonene, menthol, menthone and thymol) on Fusarium verticillioides MRC 826 growth and fumonisin B1 biosynthesis. | 2008 | Toxicon | pmid:18037463 |
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| Sun LH et al. | Individual and combined cytotoxic effects of aflatoxin B1, zearalenone, deoxynivalenol and fumonisin B1 on BRL 3A rat liver cells. | 2015 | Toxicon | pmid:25549941 |
| Abbas HK and Riley RT | The presence and phytotoxicity of fumonisins and AAL-toxin in Alternaria alternata. | 1996 | Toxicon | pmid:8835341 |
| Kouadio JH et al. | Effects of combinations of Fusarium mycotoxins on the inhibition of macromolecular synthesis, malondialdehyde levels, DNA methylation and fragmentation, and viability in Caco-2 cells. | 2007 | Toxicon | pmid:17109910 |
| Zhang H et al. | Toxicity of the mycotoxin fumonisin B on the insect Sf9 cell line. | 2017 | Toxicon | pmid:28153490 |
| Albonico M et al. | In vitro effects of the Fusarium mycotoxins fumonisin B and beauvericin on bovine granulosa cell proliferation and steroid production. | 2017 | Toxicon | pmid:28132864 |
| Clarke R et al. | Cytotoxic assessment of the regulated, co-existing mycotoxins aflatoxin B1, fumonisin B1 and ochratoxin, in single, binary and tertiary mixtures. | 2014 | Toxicon | pmid:25110174 |
| van der Westhuizen L et al. | The effect of repeated gavage doses of fumonisin B1 on the sphinganine and sphingosine levels in vervet monkeys. | 2001 | Toxicon | pmid:11223085 |
| Abbas HK et al. | Biological activities of fumonisins, mycotoxins from Fusarium moniliforme, in jimsonweed (Datura stramonium L.) and mammalian cell cultures. | 1993 | Toxicon | pmid:8470138 |
| Ling S et al. | Rapid detection of fumonisin B1 using a colloidal gold immunoassay strip test in corn samples. | 2015 | Toxicon | pmid:26525659 |
| Gelderblom WC et al. | Interaction of fumonisin B(1) and aflatoxin B(1) in a short-term carcinogenesis model in rat liver. | 2002 | Toxicology | pmid:11836022 |
| Bhandari N and Sharma RP | Fumonisin B(1)-induced alterations in cytokine expression and apoptosis signaling genes in mouse liver and kidney after an acute exposure. | 2002 | Toxicology | pmid:11882348 |
| Sharma N et al. | Augmented fumonisin B1 toxicity in co-cultures: evidence for crosstalk between macrophages and non-parenchymatous liver epithelial cells involving proinflammatory cytokines. | 2004 | Toxicology | pmid:15363598 |
| Stockmann-Juvala H et al. | Fumonisin B1-induced toxicity and oxidative damage in U-118MG glioblastoma cells. | 2004 | Toxicology | pmid:15337581 |
| Halloy DJ et al. | Oral exposure to culture material extract containing fumonisins predisposes swine to the development of pneumonitis caused by Pasteurellamultocida. | 2005 | Toxicology | pmid:15979225 |
| Stockmann-Juvala H et al. | Fumonisin B1-induced apoptosis in neuroblastoma, glioblastoma and hypothalamic cell lines. | 2006 | Toxicology | pmid:16860453 |
| Lock EA et al. | Caspase-dependent and -independent induction of phosphatidylserine externalization during apoptosis in human renal carcinoma Cak(1)-1 and A-498 cells. | 2007 | Toxicology | pmid:17097791 |
| Sharma N et al. | Amelioration of fumonisin B1 hepatotoxicity in mice by depletion of T cells with anti-Thy-1.2. | 2006 | Toxicology | pmid:16690192 |
| Gopee NV and Sharma RP | Sphingoid bases and their phosphates: transient activation and delayed repression of protein kinase C isoforms and their possible involvement in fumonisin B1 cytotoxicity. | 2003 | Toxicology | pmid:12699912 |
| Mobio TA et al. | Comparative study of the toxic effects of fumonisin B1 in rat C6 glioma cells and p53-null mouse embryo fibroblasts. | 2003 | Toxicology | pmid:12504343 |
| Theumer MG et al. | Immunobiological effects of AFB1 and AFB1-FB1 mixture in experimental subchronic mycotoxicoses in rats. | 2003 | Toxicology | pmid:12604180 |
| Rumora L et al. | Mycotoxin fumonisin B1 alters cellular redox balance and signalling pathways in rat liver and kidney. | 2007 | Toxicology | pmid:17949882 |
| Kouadio JH et al. | Comparative study of cytotoxicity and oxidative stress induced by deoxynivalenol, zearalenone or fumonisin B1 in human intestinal cell line Caco-2. | 2005 | Toxicology | pmid:16019124 |
| Sharma RP et al. | Tolerance to fumonisin toxicity in a mouse strain lacking the P75 tumor necrosis factor receptor. | 2000 | Toxicology | pmid:10755704 |
| Chuturgoon A et al. | Fumonisin B1 induces global DNA hypomethylation in HepG2 cells - An alternative mechanism of action. | 2014 | Toxicology | pmid:24280379 |
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| Voss KA et al. | The role of tumor necrosis factor alpha and the peroxisome proliferator-activated receptor alpha in modulating the effects of fumonisin in mouse liver. | 2006 | Toxicology | pmid:16574297 |
| Sharma RP et al. | Lupus-prone NZBWF1/J mice, defective in cytokine signaling, are resistant to fumonisin hepatotoxicity despite accumulation of liver sphinganine. | 2005 | Toxicology | pmid:16159691 |
| Abel S and Gelderblom WC | Oxidative damage and fumonisin B1-induced toxicity in primary rat hepatocytes and rat liver in vivo. | 1998 | Toxicology | pmid:9928627 |
| Romero A et al. | Mycotoxins modify the barrier function of Caco-2 cells through differential gene expression of specific claudin isoforms: Protective effect of illite mineral clay. | 2016 | Toxicology | pmid:27153755 |
| Gumprecht LA et al. | Species and organ specificity of fumonisin-induced endothelial alterations: potential role in porcine pulmonary edema. | 2001 | Toxicology | pmid:11246126 |
| Sharma RP et al. | Decreased fumonisin hepatotoxicity in mice with a targeted deletion of tumor necrosis factor receptor 1. | 2001 | Toxicology | pmid:11250056 |
| Mary VS et al. | Reactive oxygen species sources and biomolecular oxidative damage induced by aflatoxin B1 and fumonisin B1 in rat spleen mononuclear cells. | 2012 | Toxicology | pmid:22981896 |