fumonisin b1

fumonisin b1 is a lipid of Sphingolipids (SP) class. Fumonisin b1 is associated with abnormalities such as Infection, Kidney Diseases, Liver diseases, DERMATITIS HERPETIFORMIS, FAMILIAL and Malnutrition. The involved functions are known as Gene Expression, Anabolism, Signal, Biosynthetic Pathways and Regulation. Fumonisin b1 often locates in Body tissue, Microsomes, microsomal membrane, Protoplasm and Mitochondria. The associated genes with fumonisin b1 are Genome, P4HTM gene, FATE1 gene, BCL2 gene and TMEM132D gene. The related lipids are dihydroceramide, ceramide 1-phosphate, Sphingolipids, Fatty Acids and Palmitates.

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Introduction

To understand associated biological information of fumonisin b1, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with fumonisin b1?

fumonisin b1 is suspected in Infection, Kidney Diseases, Liver diseases, DERMATITIS HERPETIFORMIS, FAMILIAL, Malnutrition, Celiac Disease and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with fumonisin b1

MeSH term MeSH ID Detail
Stomach Ulcer D013276 75 associated lipids
Adenocarcinoma D000230 166 associated lipids
Lung Diseases D008171 37 associated lipids
Lung Neoplasms D008175 171 associated lipids
Kidney Neoplasms D007680 29 associated lipids
Inflammation D007249 119 associated lipids
Fatty Liver D005234 48 associated lipids
Body Weight D001835 333 associated lipids
Esophageal Neoplasms D004938 20 associated lipids
Precancerous Conditions D011230 48 associated lipids
Per page 10 20 50 100 | Total 54

PubChem Associated disorders and diseases

What pathways are associated with fumonisin b1

Lipid pathways are not clear in current pathway databases. We organized associated pathways with fumonisin b1 through full-text articles, including metabolic pathways or pathways of biological mechanisms.

Related references are published most in these journals:

Pathway name Related literatures
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PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with fumonisin b1?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with fumonisin b1?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with fumonisin b1?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with fumonisin b1?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with fumonisin b1?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with fumonisin b1

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Per page 10 20 50 100 | Total 1278
Authors Title Published Journal PubMed Link
Luongo D et al. Effects of four Fusarium toxins (fumonisin B(1), alpha-zearalenol, nivalenol and deoxynivalenol) on porcine whole-blood cellular proliferation. 2008 Toxicon pmid:18620720
Ficheux AS et al. Co-exposure of Fusarium mycotoxins: in vitro myelotoxicity assessment on human hematopoietic progenitors. 2012 Toxicon pmid:22921581
van der Westhuizen L et al. The effect of a single gavage dose of fumonisin B(1) on the sphinganine and sphingosine levels in vervet monkeys. 2001 Feb-Mar Toxicon pmid:10978745
Caloni F et al. Evaluation of Fumonisin B(1) and its metabolites absorption and toxicity on intestinal cells line Caco-2. 2002 Toxicon pmid:12165322
Sauviat MP et al. Fumonisin, a toxin from the fungus Fusarium moniliforme sheld, blocks both the calcium current and the mechanical activity in frog atrial muscle. 1991 Toxicon pmid:1658988
Shephard GS et al. Fate of a single dose of the 14C-labelled mycotoxin, fumonisin B1, in rats. 1992 Toxicon pmid:1509495
Dambolena JS et al. Inhibitory effect of cyclic terpenes (limonene, menthol, menthone and thymol) on Fusarium verticillioides MRC 826 growth and fumonisin B1 biosynthesis. 2008 Toxicon pmid:18037463
Sheng Y et al. Development of a sensitive enzyme-linked immunosorbent assay for the detection of fumonisin B₁ in maize. 2012 Toxicon pmid:22960014
Shephard GS et al. Disruption of sphingolipid metabolism in non-human primates consuming diets of fumonisin-containing Fusarium moniliforme culture material. 1996 Toxicon pmid:8783447
He Q and Sharma RP Inhibition of tumor necrosis factor alpha signaling by anti-tumor necrosis factor alpha antibodies and pentoxifylline is unable to prevent fumonisin hepatotoxicity in mice. 2005 Toxicon pmid:16054185
Sun LH et al. Individual and combined cytotoxic effects of aflatoxin B1, zearalenone, deoxynivalenol and fumonisin B1 on BRL 3A rat liver cells. 2015 Toxicon pmid:25549941
Abbas HK and Riley RT The presence and phytotoxicity of fumonisins and AAL-toxin in Alternaria alternata. 1996 Toxicon pmid:8835341
Zhang H et al. Toxicity of the mycotoxin fumonisin B on the insect Sf9 cell line. 2017 Toxicon pmid:28153490
Albonico M et al. In vitro effects of the Fusarium mycotoxins fumonisin B and beauvericin on bovine granulosa cell proliferation and steroid production. 2017 Toxicon pmid:28132864
Clarke R et al. Cytotoxic assessment of the regulated, co-existing mycotoxins aflatoxin B1, fumonisin B1 and ochratoxin, in single, binary and tertiary mixtures. 2014 Toxicon pmid:25110174
Abbas HK et al. Biological activities of fumonisins, mycotoxins from Fusarium moniliforme, in jimsonweed (Datura stramonium L.) and mammalian cell cultures. 1993 Toxicon pmid:8470138
Ling S et al. Rapid detection of fumonisin B1 using a colloidal gold immunoassay strip test in corn samples. 2015 Toxicon pmid:26525659
Domijan AM et al. Standard and Fpg-modified comet assay in kidney cells of ochratoxin A- and fumonisin B(1)-treated rats. 2006 Toxicology pmid:16497426
Suzuki H et al. Inducible nitric oxide has protective effect on fumonisin B1 hepatotoxicity in mice via modulation of sphingosine kinase. 2007 Toxicology pmid:17095132
Sharma RP et al. Decreased fumonisin hepatotoxicity in mice with a targeted deletion of tumor necrosis factor receptor 1. 2001 Toxicology pmid:11250056