| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| pmid: | ||||
| Salcedo M et al. | The marine sphingolipid-derived compound ES 285 triggers an atypical cell death pathway. | 2007 | Apoptosis | pmid:17191124 |
| Stokvis E et al. | A more sensitive MS detector does not obviously lead to a more sensitive assay: experiences with ES-285. | 2004 | Biomed. Chromatogr. | pmid:15273982 |
| Schöffski P et al. | Spisulosine (ES-285) given as a weekly three-hour intravenous infusion: results of a phase I dose-escalating study in patients with advanced solid malignancies. | 2011 | Cancer Chemother. Pharmacol. | pmid:21465314 |
| Cuadros R et al. | The marine compound spisulosine, an inhibitor of cell proliferation, promotes the disassembly of actin stress fibers. | 2000 | Cancer Lett. | pmid:10754202 |
| FabiÅ¡Ãková M et al. | Total synthesis and the anticancer activity of (+)-spisulosine. | 2016 | Carbohydr. Res. | pmid:27693911 |
| Merrill AH | Sphingolipid and glycosphingolipid metabolic pathways in the era of sphingolipidomics. | 2011 | Chem. Rev. | pmid:21942574 |
| Xu K et al. | A highly anti-selective asymmetric Henry reaction catalyzed by a chiral copper complex: applications to the syntheses of (+)-spisulosine and a pyrroloisoquinoline derivative. | 2012 | Chemistry | pmid:22907874 |
| Kowluru A | Deoxysphingolipids: β-cell, beware of these new kids on the block. | 2014 | Diabetes | pmid:24651803 |
| Zuellig RA et al. | Deoxysphingolipids, novel biomarkers for type 2 diabetes, are cytotoxic for insulin-producing cells. | 2014 | Diabetes | pmid:24379346 |
Spisulosine
Spisulosine is a lipid of Sphingolipids (SP) class. Spisulosine is associated with abnormalities such as Infection, Renal impairment and Lesion of brain. The involved functions are known as Gene Expression, Cell Cycle, Drug Kinetics, Signal Transduction and Cell Cycle Arrest. Spisulosine often locates in Body tissue, Microfilaments, Skin, Stress Fibers and Tissue specimen.
Cross Reference
Introduction
To understand associated biological information of Spisulosine, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with Spisulosine?
Spisulosine is suspected in Infection, Renal impairment, Lesion of brain and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
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No disease MeSH terms mapped to the current reference collection.
PubChem Associated disorders and diseases
What pathways are associated with Spisulosine
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with Spisulosine?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
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What functions are associated with Spisulosine?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with Spisulosine?
There are no associated biomedical information in the current reference collection.
What genes are associated with Spisulosine?
There are no associated biomedical information in the current reference collection.
What common seen animal models are associated with Spisulosine?
There are no associated biomedical information in the current reference collection.