|
|
|
|
pmid:
|
Zhang TH et al. |
Ceramide induces apoptosis in human lung adenocarcinoma A549 cells through mitogen-activated protein kinases. |
2007 |
Acta Pharmacol. Sin. |
pmid:17303009
|
Hanna AN et al. |
Tumor necrosis factor-alpha, sphingomyelinase and ceramides activate tyrosine kinase, p21Ras and phosphatidylinositol 3-kinase: implications for glucose transport and insulin resistance. |
2001 |
Adv. Exp. Med. Biol. |
pmid:11900368
|
Chik CL et al. |
Ceramide inhibits L-type calcium channel currents in rat pinealocytes. |
1999 |
Adv. Exp. Med. Biol. |
pmid:10810500
|
Chmura SJ et al. |
Cross-talk between ceramide and PKC activity in the control of apoptosis in WEHI-231. |
1996 |
Adv. Exp. Med. Biol. |
pmid:8910670
|
Bielawska AE et al. |
Ceramide is involved in triggering of cardiomyocyte apoptosis induced by ischemia and reperfusion. |
1997 |
Am. J. Pathol. |
pmid:9358751
|
Kimura T et al. |
Inhibition of TSH-induced hydrogen peroxide production by TNF-alpha through a sphingomyelinase signaling pathway. |
1997 |
Am. J. Physiol. |
pmid:9316456
|
Ibitayo AI et al. |
Src kinase and PI 3-kinase as a transduction pathway in ceramide-induced contraction of colonic smooth muscle. |
1998 |
Am. J. Physiol. |
pmid:9756500
|
Yorek MA et al. |
Effect of TNF-alpha on SMIT mRNA levels and myo-inositol accumulation in cultured endothelial cells. |
1998 |
Am. J. Physiol. |
pmid:9458713
|
Su X et al. |
Differential activation of phosphoinositide 3-kinase by endothelin and ceramide in colonic smooth muscle cells. |
1999 |
Am. J. Physiol. |
pmid:10198327
|
Wang P and Bitar KN |
Rho A regulates sustained smooth muscle contraction through cytoskeletal reorganization of HSP27. |
1998 |
Am. J. Physiol. |
pmid:9843784
|
Bitar KN |
HSP27 phosphorylation and interaction with actin-myosin in smooth muscle contraction. |
2002 |
Am. J. Physiol. Gastrointest. Liver Physiol. |
pmid:11960785
|
Soltys CL et al. |
Phosphorylation of cardiac protein kinase B is regulated by palmitate. |
2002 |
Am. J. Physiol. Heart Circ. Physiol. |
pmid:12181135
|
Liu SJ and Kennedy RH |
Positive inotropic effect of ceramide in adult ventricular myocytes: mechanisms dissociated from its reduction in Ca2+ influx. |
2003 |
Am. J. Physiol. Heart Circ. Physiol. |
pmid:12730052
|
Sparkman L et al. |
Ceramide decreases surfactant protein B gene expression via downregulation of TTF-1 DNA binding activity. |
2006 |
Am. J. Physiol. Lung Cell Mol. Physiol. |
pmid:16183668
|
Liu J et al. |
Hypoxic preconditioning protects cultured neurons against hypoxic stress via TNF-alpha and ceramide. |
2000 |
Am. J. Physiol., Cell Physiol. |
pmid:10644522
|
Kawano Y et al. |
Synergistic effect of interleukin-1alpha and ceramide analogue on production of prostaglandin E2 and F2alpha by endometrial stromal cells. |
2001 |
Am. J. Reprod. Immunol. |
pmid:11775008
|
Chan C and Goldkorn T |
Ceramide path in human lung cell death. |
2000 |
Am. J. Respir. Cell Mol. Biol. |
pmid:10745027
|
Graf C et al. |
A secondary assay for ceramide kinase inhibitors based on cell growth inhibition by short-chain ceramides. |
2009 |
Anal. Biochem. |
pmid:18831956
|
Degnan BM et al. |
Sphingomyelinase inhibits in vitro Leydig cell function. |
1996 May-Jun |
Ann. Clin. Lab. Sci. |
pmid:8726216
|
Condrescu M et al. |
Cellular regulation of sodium-calcium exchange. |
2002 |
Ann. N. Y. Acad. Sci. |
pmid:12502564
|
Kristal BS and Brown AM |
Ganglioside GD3, the mitochondrial permeability transition, and apoptosis. |
1999 |
Ann. N. Y. Acad. Sci. |
pmid:10672258
|
Mizushima N et al. |
Ceramide, a mediator of interleukin 1, tumour necrosis factor alpha, as well as Fas receptor signalling, induces apoptosis of rheumatoid arthritis synovial cells. |
1998 |
Ann. Rheum. Dis. |
pmid:9797556
|
Shklyaev SS et al. |
Involvement of wild-type p53 in radiation-induced c-Jun N-terminal kinase activation in human thyroid cells. |
2001 Jul-Aug |
Anticancer Res. |
pmid:11724323
|
Ahn EH and Schroeder JJ |
Induction of apoptosis by sphingosine, sphinganine, and C(2)-ceramide in human colon cancer cells, but not by C(2)-dihydroceramide. |
2010 |
Anticancer Res. |
pmid:20683027
|
Wang J et al. |
Ceramide induces apoptosis via a peroxisome proliferator-activated receptor gamma-dependent pathway. |
2006 |
Apoptosis |
pmid:17036198
|
Woo KJ et al. |
Bcl-2 attenuates anticancer agents-induced apoptosis by sustained activation of Akt/protein kinase B in U937 cells. |
2005 |
Apoptosis |
pmid:16215670
|
Hearps AC et al. |
Mitochondrial cytochrome c release precedes transmembrane depolarisation and caspase-3 activation during ceramide-induced apoptosis of Jurkat T cells. |
2002 |
Apoptosis |
pmid:12207171
|
Jiang S et al. |
C2-ceramide enhances sorafenib-induced caspase-dependent apoptosis via PI3K/AKT/mTOR and Erk signaling pathways in HCC cells. |
2017 |
Appl. Microbiol. Biotechnol. |
pmid:27807662
|
Kolettas E et al. |
Bcl-2 but not clusterin/apolipoprotein J protected human diploid fibroblasts and immortalized keratinocytes from ceramide-induced apoptosis: role of p53 in the ceramide response. |
2006 |
Arch. Biochem. Biophys. |
pmid:16297852
|
Belichenko I et al. |
Caspase-resistant vimentin suppresses apoptosis after photodynamic treatment with a silicon phthalocyanine in Jurkat cells. |
2001 |
Arch. Biochem. Biophys. |
pmid:11368515
|
Phillips DC et al. |
Synthetic ceramides induce growth arrest or apoptosis by altering cellular redox status. |
2002 |
Arch. Biochem. Biophys. |
pmid:12392710
|
Kong JY and Rabkin SW |
Mitochondrial effects with ceramide-induced cardiac apoptosis are different from those of palmitate. |
2003 |
Arch. Biochem. Biophys. |
pmid:12667483
|
Ji L et al. |
Effects of endoglycoceramidase or D-threo-1-phenyl-2-decanoylamino-3-morpholino-1-propanol on glucose uptake, glycolysis, and mitochondrial respiration in HL60 cells. |
1998 |
Arch. Biochem. Biophys. |
pmid:9799567
|
Furuchi T et al. |
Apoptotic inducers activate the release of D-aspartate through a hypotonic stimulus-triggered mechanism in PC12 cells. |
2009 |
Arch. Biochem. Biophys. |
pmid:19720044
|
Müller-Wieprecht V et al. |
Bcl-2 transfected HaCaT keratinocytes resist apoptotic signals of ceramides, tumor necrosis factor alpha and 1 alpha, 25-dihydroxyvitamin D(3). |
2000 |
Arch. Dermatol. Res. |
pmid:11000289
|
Park JY et al. |
Ceramide induces apoptosis via caspase-dependent and caspase-independent pathways in mesenchymal stem cells derived from human adipose tissue. |
2011 |
Arch. Toxicol. |
pmid:21259059
|
Kim SK et al. |
Palmitate induces RIP1-dependent necrosis in RAW 264.7 cells. |
2012 |
Atherosclerosis |
pmid:23084711
|
Dekker MJ et al. |
Inhibition of sphingolipid synthesis improves dyslipidemia in the diet-induced hamster model of insulin resistance: evidence for the role of sphingosine and sphinganine in hepatic VLDL-apoB100 overproduction. |
2013 |
Atherosclerosis |
pmid:23466071
|
Adachi T et al. |
Membrane microdomain formation is crucial in epiboly during gastrulation of medaka. |
2007 |
Biochem. Biophys. Res. Commun. |
pmid:17511962
|
Ito Y et al. |
Reduction of airway anion secretion via CFTR in sphingomyelin pathway. |
2004 |
Biochem. Biophys. Res. Commun. |
pmid:15474513
|
Perks CM et al. |
A non-IGF binding mutant of IGFBP-3 modulates cell function in breast epithelial cells. |
2002 |
Biochem. Biophys. Res. Commun. |
pmid:12074574
|
Di Bartolomeo S et al. |
Differential apoptotic effect and metabolism of N-acetylsphingosine and N-hexanoylsphingosine in CHP-100 human neurotumor cells. |
2015 |
Biochem. Biophys. Res. Commun. |
pmid:25656578
|
Kim HS et al. |
Induction of apoptosis by all-trans-retinoic acid and C2-ceramide treatment in rat stromal-vascular cultures. |
2000 |
Biochem. Biophys. Res. Commun. |
pmid:10733907
|
Ito M |
Insulin or bFGF and C2 ceramide increase newborn rat retinal ganglion cell survival rate. |
2003 |
Biochem. Biophys. Res. Commun. |
pmid:12565900
|
Movsesyan VA et al. |
Ceramide induces neuronal apoptosis through the caspase-9/caspase-3 pathway. |
2002 |
Biochem. Biophys. Res. Commun. |
pmid:12437970
|
Mihai R et al. |
C2-Ceramide increases cytoplasmic calcium concentrations in human parathyroid cells. |
2000 |
Biochem. Biophys. Res. Commun. |
pmid:10679256
|
Migita K et al. |
Regulation of rheumatoid synovial cell growth by ceramide. |
2000 |
Biochem. Biophys. Res. Commun. |
pmid:10694479
|
Buisson-Legendre N et al. |
Involvement of the 92-kDa gelatinase (matrix metalloproteinase-9) in the ceramide-mediated inhibition of human keratinocyte growth. |
1999 |
Biochem. Biophys. Res. Commun. |
pmid:10403818
|
Cheng YL et al. |
Increased galectin-3 facilitates leukemia cell survival from apoptotic stimuli. |
2011 |
Biochem. Biophys. Res. Commun. |
pmid:21821001
|