N-acetylsphingosine
N-acetylsphingosine is a lipid of Sphingolipids (SP) class. N-acetylsphingosine is associated with abnormalities such as Morphologically altered structure, Atherosclerosis, Cardiovascular Diseases, Hyperinsulinism and Gigantism. The involved functions are known as inhibitors, anti-apoptosis, Apoptosis, Dephosphorylation and immunoreactivity. N-acetylsphingosine often locates in Plasma membrane, Mitochondria, Pore, Membrane and Cytoplasmic matrix. The associated genes with N-acetylsphingosine are EGR3 gene, CFB gene, FATE1 gene, P4HTM gene and PFDN4 gene. The related lipids are Sphingolipids, Cardiolipins, Glycerophospholipids, dihydroceramide and Phosphatidic Acid.
Cross Reference
Introduction
To understand associated biological information of N-acetylsphingosine, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with N-acetylsphingosine?
N-acetylsphingosine is suspected in Morphologically altered structure, protrusion, DERMATITIS HERPETIFORMIS, FAMILIAL, Atherosclerosis, Cardiovascular Diseases, Hyperinsulinism and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with N-acetylsphingosine
PubChem Associated disorders and diseases
What pathways are associated with N-acetylsphingosine
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with N-acetylsphingosine?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
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What functions are associated with N-acetylsphingosine?
Related references are published most in these journals:
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What lipids are associated with N-acetylsphingosine?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
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What genes are associated with N-acetylsphingosine?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
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What common seen animal models are associated with N-acetylsphingosine?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with N-acetylsphingosine
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Huang Y et al. | [Ceramide participates in cell programmed death induced by Type II anti-CD20 mAb]. | 2015 | Zhong Nan Da Xue Xue Bao Yi Xue Ban | pmid:26739069 |
| Ogiso H et al. | Analysis of lipid-composition changes in plasma membrane microdomains. | 2015 | J. Lipid Res. | pmid:26116739 |
| Wehinger S et al. | Phosphorylation of caveolin-1 on tyrosine-14 induced by ROS enhances palmitate-induced death of beta-pancreatic cells. | 2015 | Biochim. Biophys. Acta | pmid:25572853 |
| Di Bartolomeo S et al. | Differential apoptotic effect and metabolism of N-acetylsphingosine and N-hexanoylsphingosine in CHP-100 human neurotumor cells. | 2015 | Biochem. Biophys. Res. Commun. | pmid:25656578 |
| Freed JK et al. | Ceramide changes the mediator of flow-induced vasodilation from nitric oxide to hydrogen peroxide in the human microcirculation. | 2014 | Circ. Res. | pmid:24920698 |
| Zhu W et al. | C2-ceramide induces cell death and protective autophagy in head and neck squamous cell carcinoma cells. | 2014 | Int J Mol Sci | pmid:24566153 |
| Tan KB et al. | Liposomal codelivery of a synergistic combination of bioactive lipids in the treatment of acute myeloid leukemia. | 2014 | Nanomedicine (Lond) | pmid:24294981 |
| Leanza L et al. | Correlation between potassium channel expression and sensitivity to drug-induced cell death in tumor cell lines. | 2014 | Curr. Pharm. Des. | pmid:23701546 |
| Hsieh CT et al. | Ceramide inhibits insulin-stimulated Akt phosphorylation through activation of Rheb/mTORC1/S6K signaling in skeletal muscle. | 2014 | Cell. Signal. | pmid:24650522 |
| Costanzi E et al. | Hypermethylation contributes to down-regulation of lysosomal β-hexosaminidase α subunit in prostate cancer cells. | 2014 | Biochimie | pmid:24389457 |