N-acetylsphingosine is a lipid of Sphingolipids (SP) class. N-acetylsphingosine is associated with abnormalities such as Morphologically altered structure, Atherosclerosis, Cardiovascular Diseases, Hyperinsulinism and Gigantism. The involved functions are known as inhibitors, anti-apoptosis, Apoptosis, Dephosphorylation and immunoreactivity. N-acetylsphingosine often locates in Plasma membrane, Mitochondria, Pore, Membrane and Cytoplasmic matrix. The associated genes with N-acetylsphingosine are EGR3 gene, CFB gene, FATE1 gene, P4HTM gene and PFDN4 gene. The related lipids are Sphingolipids, Cardiolipins, Glycerophospholipids, dihydroceramide and Phosphatidic Acid.
To understand associated biological information of N-acetylsphingosine, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
N-acetylsphingosine is suspected in Morphologically altered structure, protrusion, DERMATITIS HERPETIFORMIS, FAMILIAL, Atherosclerosis, Cardiovascular Diseases, Hyperinsulinism and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
---|
We collected disease MeSH terms mapped to the references associated with N-acetylsphingosine
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
---|
Function | Cross reference | Weighted score | Related literatures |
---|
Lipid concept | Cross reference | Weighted score | Related literatures |
---|
Gene | Cross reference | Weighted score | Related literatures |
---|
There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
---|---|---|---|---|
Martins I et al. | Chemotherapy induces ATP release from tumor cells. | 2009 | Cell Cycle | pmid:19855167 |
Jeng JY et al. | Functional modulation of mitochondria by eicosapentaenoic acid provides protection against ceramide toxicity to C6 glioma cells. | 2009 | J. Agric. Food Chem. | pmid:19921818 |
Masgrau R et al. | BM88/Cend1 regulates stimuli-induced intracellular calcium mobilization. | 2009 | Neuropharmacology | pmid:19061903 |
Gubern A et al. | Lipid droplet biogenesis induced by stress involves triacylglycerol synthesis that depends on group VIA phospholipase A2. | 2009 | J. Biol. Chem. | pmid:19117952 |
de Castro e Paula LA and Hansen PJ | Ceramide inhibits development and cytokinesis and induces apoptosis in preimplantation bovine embryos. | 2008 | Mol. Reprod. Dev. | pmid:18157869 |
Miñano A et al. | C2-ceramide mediates cerebellar granule cells apoptosis by activation of caspases-2, -9, and -3. | 2008 | J. Neurosci. Res. | pmid:18311838 |
Nicol GD | Nerve growth factor, sphingomyelins, and sensitization in sensory neurons. | 2008 | Sheng Li Xue Bao | pmid:18958367 |
Lim JY et al. | Investigation on C2-ceramide complexes with transition metal ions using electrospray ionization tandem mass spectrometry. | 2008 | Eur J Mass Spectrom (Chichester, Eng) | pmid:18493098 |
Chen CL et al. | Ceramide induces p38 MAPK and JNK activation through a mechanism involving a thioredoxin-interacting protein-mediated pathway. | 2008 | Blood | pmid:18270325 |
Elner SG et al. | Retinal flavoprotein autofluorescence as a measure of retinal health. | 2008 | Trans Am Ophthalmol Soc | pmid:19277237 |