N-acetylsphingosine is a lipid of Sphingolipids (SP) class. N-acetylsphingosine is associated with abnormalities such as Morphologically altered structure, Atherosclerosis, Cardiovascular Diseases, Hyperinsulinism and Gigantism. The involved functions are known as inhibitors, anti-apoptosis, Apoptosis, Dephosphorylation and immunoreactivity. N-acetylsphingosine often locates in Plasma membrane, Mitochondria, Pore, Membrane and Cytoplasmic matrix. The associated genes with N-acetylsphingosine are EGR3 gene, CFB gene, FATE1 gene, P4HTM gene and PFDN4 gene. The related lipids are Sphingolipids, Cardiolipins, Glycerophospholipids, dihydroceramide and Phosphatidic Acid.
To understand associated biological information of N-acetylsphingosine, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
N-acetylsphingosine is suspected in Morphologically altered structure, protrusion, DERMATITIS HERPETIFORMIS, FAMILIAL, Atherosclerosis, Cardiovascular Diseases, Hyperinsulinism and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
---|
We collected disease MeSH terms mapped to the references associated with N-acetylsphingosine
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
---|
Function | Cross reference | Weighted score | Related literatures |
---|
Lipid concept | Cross reference | Weighted score | Related literatures |
---|
Gene | Cross reference | Weighted score | Related literatures |
---|
There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
---|---|---|---|---|
Nakao S et al. | C2-ceramide inhibits the prostaglandin E2-induced accumulation of cAMP in human gingival fibroblasts. | 2010 | Biomed. Res. | pmid:20460737 |
Lee YG et al. | Cell-permeable ceramides act as novel regulators of U937 cell-cell adhesion mediated by CD29, CD98, and CD147. | 2010 | Immunobiology | pmid:19576658 |
Martins I et al. | Chemotherapy induces ATP release from tumor cells. | 2009 | Cell Cycle | pmid:19855167 |
Jeng JY et al. | Functional modulation of mitochondria by eicosapentaenoic acid provides protection against ceramide toxicity to C6 glioma cells. | 2009 | J. Agric. Food Chem. | pmid:19921818 |
Fontés G et al. | Involvement of Per-Arnt-Sim Kinase and extracellular-regulated kinases-1/2 in palmitate inhibition of insulin gene expression in pancreatic beta-cells. | 2009 | Diabetes | pmid:19502418 |
Kang JH et al. | Ceramides: branched alkyl chains in the sphingolipid siblings of diacylglycerol improve biological potency. | 2009 | Bioorg. Med. Chem. | pmid:19171486 |
Graf C et al. | A secondary assay for ceramide kinase inhibitors based on cell growth inhibition by short-chain ceramides. | 2009 | Anal. Biochem. | pmid:18831956 |
Furuchi T et al. | Apoptotic inducers activate the release of D-aspartate through a hypotonic stimulus-triggered mechanism in PC12 cells. | 2009 | Arch. Biochem. Biophys. | pmid:19720044 |
Masgrau R et al. | BM88/Cend1 regulates stimuli-induced intracellular calcium mobilization. | 2009 | Neuropharmacology | pmid:19061903 |
Gubern A et al. | Lipid droplet biogenesis induced by stress involves triacylglycerol synthesis that depends on group VIA phospholipase A2. | 2009 | J. Biol. Chem. | pmid:19117952 |