N-acetylsphingosine is a lipid of Sphingolipids (SP) class. N-acetylsphingosine is associated with abnormalities such as Morphologically altered structure, Atherosclerosis, Cardiovascular Diseases, Hyperinsulinism and Gigantism. The involved functions are known as inhibitors, anti-apoptosis, Apoptosis, Dephosphorylation and immunoreactivity. N-acetylsphingosine often locates in Plasma membrane, Mitochondria, Pore, Membrane and Cytoplasmic matrix. The associated genes with N-acetylsphingosine are EGR3 gene, CFB gene, FATE1 gene, P4HTM gene and PFDN4 gene. The related lipids are Sphingolipids, Cardiolipins, Glycerophospholipids, dihydroceramide and Phosphatidic Acid.
To understand associated biological information of N-acetylsphingosine, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
N-acetylsphingosine is suspected in Morphologically altered structure, protrusion, DERMATITIS HERPETIFORMIS, FAMILIAL, Atherosclerosis, Cardiovascular Diseases, Hyperinsulinism and other diseases in descending order of the highest number of associated sentences.
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We collected disease MeSH terms mapped to the references associated with N-acetylsphingosine
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
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Lipid concept | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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Hashizume T et al. | Different effects of cell-permeable ceramide analogs on platelet activation. | 1998 | Biochem. Mol. Biol. Int. | pmid:9556209 |
Kirtikara K et al. | An accessory role for ceramide in interleukin-1beta induced prostaglandin synthesis. | 1998 | Mol. Cell. Biochem. | pmid:9562240 |
Galvan V and Roizman B | Herpes simplex virus 1 induces and blocks apoptosis at multiple steps during infection and protects cells from exogenous inducers in a cell-type-dependent manner. | 1998 | Proc. Natl. Acad. Sci. U.S.A. | pmid:9520470 |
Durrieu F et al. | Caspase activation is an early event in anthracycline-induced apoptosis and allows detection of apoptotic cells before they are ingested by phagocytes. | 1998 | Exp. Cell Res. | pmid:9596989 |
Yorek MA et al. | Effect of TNF-alpha on SMIT mRNA levels and myo-inositol accumulation in cultured endothelial cells. | 1998 | Am. J. Physiol. | pmid:9458713 |
Centeno F et al. | Partial lithium-associated protection against apoptosis induced by C2-ceramide in cerebellar granule neurons. | 1998 | Neuroreport | pmid:9926873 |
Jaffrézou JP et al. | Positive feedback control of neutral sphingomyelinase activity by ceramide. | 1998 | FASEB J. | pmid:9707172 |
Summers SA et al. | Regulation of insulin-stimulated glucose transporter GLUT4 translocation and Akt kinase activity by ceramide. | 1998 | Mol. Cell. Biol. | pmid:9710629 |
Hartfield PJ et al. | Neurotrophic factors prevent ceramide-induced apoptosis downstream of c-Jun N-terminal kinase activation in PC12 cells. | 1998 | J. Neurochem. | pmid:9648862 |
Zhang J et al. | Regulation of membrane release in apoptosis. | 1998 | Biochem. J. | pmid:9716508 |