N-acetylsphingosine is a lipid of Sphingolipids (SP) class. N-acetylsphingosine is associated with abnormalities such as Morphologically altered structure, Atherosclerosis, Cardiovascular Diseases, Hyperinsulinism and Gigantism. The involved functions are known as inhibitors, anti-apoptosis, Apoptosis, Dephosphorylation and immunoreactivity. N-acetylsphingosine often locates in Plasma membrane, Mitochondria, Pore, Membrane and Cytoplasmic matrix. The associated genes with N-acetylsphingosine are EGR3 gene, CFB gene, FATE1 gene, P4HTM gene and PFDN4 gene. The related lipids are Sphingolipids, Cardiolipins, Glycerophospholipids, dihydroceramide and Phosphatidic Acid.
To understand associated biological information of N-acetylsphingosine, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
N-acetylsphingosine is suspected in Morphologically altered structure, protrusion, DERMATITIS HERPETIFORMIS, FAMILIAL, Atherosclerosis, Cardiovascular Diseases, Hyperinsulinism and other diseases in descending order of the highest number of associated sentences.
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We collected disease MeSH terms mapped to the references associated with N-acetylsphingosine
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
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Lipid concept | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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Lecour S et al. | Ceramide-induced preconditioning involves reactive oxygen species. | 2006 | Life Sci. | pmid:16293265 |
Bianchi K et al. | Regulation of Ca2+ signalling and Ca2+-mediated cell death by the transcriptional coactivator PGC-1alpha. | 2006 | Cell Death Differ. | pmid:16239931 |
Schumacher AM et al. | Death-associated protein kinase phosphorylates mammalian ribosomal protein S6 and reduces protein synthesis. | 2006 | Biochemistry | pmid:17087515 |
MacRae VE et al. | Ceramide inhibition of chondrocyte proliferation and bone growth is IGF-I independent. | 2006 | J. Endocrinol. | pmid:17088406 |
Chen S et al. | Amyloid beta peptide increases DP5 expression via activation of neutral sphingomyelinase and JNK in oligodendrocytes. | 2006 | J. Neurochem. | pmid:16524368 |
Tabarean IV et al. | Interleukin-1beta induces hyperpolarization and modulates synaptic inhibition in preoptic and anterior hypothalamic neurons. | 2006 | Neuroscience | pmid:16777343 |
Strle K et al. | C-jun N-terminal kinase mediates tumor necrosis factor-alpha suppression of differentiation in myoblasts. | 2006 | Endocrinology | pmid:16777978 |
Xin M and Deng X | Protein phosphatase 2A enhances the proapoptotic function of Bax through dephosphorylation. | 2006 | J. Biol. Chem. | pmid:16679323 |
German OL et al. | Ceramide is a mediator of apoptosis in retina photoreceptors. | 2006 | Invest. Ophthalmol. Vis. Sci. | pmid:16565407 |
Sparkman L et al. | Ceramide decreases surfactant protein B gene expression via downregulation of TTF-1 DNA binding activity. | 2006 | Am. J. Physiol. Lung Cell Mol. Physiol. | pmid:16183668 |