| MeSH term | MeSH ID | Detail |
|---|---|---|
| Nerve Degeneration | D009410 | 53 associated lipids |
| Melanoma | D008545 | 69 associated lipids |
| Medulloblastoma | D008527 | 22 associated lipids |
| Lung Neoplasms | D008175 | 171 associated lipids |
| Leukemia | D007938 | 74 associated lipids |
| Insulin Resistance | D007333 | 99 associated lipids |
| Carcinoma, Hepatocellular | D006528 | 140 associated lipids |
| Glioma | D005910 | 112 associated lipids |
| Fever | D005334 | 35 associated lipids |
| Eye Abnormalities | D005124 | 7 associated lipids |
N-acetylsphingosine
N-acetylsphingosine is a lipid of Sphingolipids (SP) class. N-acetylsphingosine is associated with abnormalities such as Morphologically altered structure, Atherosclerosis, Cardiovascular Diseases, Hyperinsulinism and Gigantism. The involved functions are known as inhibitors, anti-apoptosis, Apoptosis, Dephosphorylation and immunoreactivity. N-acetylsphingosine often locates in Plasma membrane, Mitochondria, Pore, Membrane and Cytoplasmic matrix. The associated genes with N-acetylsphingosine are EGR3 gene, CFB gene, FATE1 gene, P4HTM gene and PFDN4 gene. The related lipids are Sphingolipids, Cardiolipins, Glycerophospholipids, dihydroceramide and Phosphatidic Acid.
Cross Reference
Introduction
To understand associated biological information of N-acetylsphingosine, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with N-acetylsphingosine?
N-acetylsphingosine is suspected in Morphologically altered structure, protrusion, DERMATITIS HERPETIFORMIS, FAMILIAL, Atherosclerosis, Cardiovascular Diseases, Hyperinsulinism and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with N-acetylsphingosine
PubChem Associated disorders and diseases
What pathways are associated with N-acetylsphingosine
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with N-acetylsphingosine?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
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What functions are associated with N-acetylsphingosine?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
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What lipids are associated with N-acetylsphingosine?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
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What genes are associated with N-acetylsphingosine?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with N-acetylsphingosine?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with N-acetylsphingosine
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
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| Ulrich S et al. | De novo ceramide biosynthesis is associated with resveratrol-induced inhibition of ornithine decarboxylase activity. | 2007 | Biochem. Pharmacol. | pmid:17521618 |
| Fillet M et al. | Mechanisms involved in exogenous C2- and C6-ceramide-induced cancer cell toxicity. | 2003 | Biochem. Pharmacol. | pmid:12754099 |
| Kowluru A | Friendly, and not so friendly, roles of Rac1 in islet β-cell function: lessons learnt from pharmacological and molecular biological approaches. | 2011 | Biochem. Pharmacol. | pmid:21300027 |
| Allan D et al. | Mechanisms by which short-chain ceramides cause apoptosis. | 1999 | Biochem. Soc. Trans. | pmid:10917615 |
| Schumacher AM et al. | Death-associated protein kinase phosphorylates mammalian ribosomal protein S6 and reduces protein synthesis. | 2006 | Biochemistry | pmid:17087515 |
| Singh IN et al. | Ceramide inhibition of mammalian phospholipase D1 and D2 activities is antagonized by phosphatidylinositol 4,5-bisphosphate. | 2001 | Biochemistry | pmid:11551222 |
| Simon CG and Gear AR | Membrane-destabilizing properties of C2-ceramide may be responsible for its ability to inhibit platelet aggregation. | 1998 | Biochemistry | pmid:9485333 |
| Galadari S et al. | Purification and characterization of ceramide-activated protein phosphatases. | 1998 | Biochemistry | pmid:9698369 |
| Ogura M and Handa S | Induction of apoptosis by novel synthesized acylamides of human lymphocytes. | 2000 | Biochim. Biophys. Acta | pmid:10601700 |